杨连东　副研究员博士研究生

职　　称： 副研究员
学　　历： 博士研究生
联系方式： 86-
电子邮件： yangld#ihb.ac.cn(请改#为@)
办公室： 标本馆307
个人网页： https://www.researchgate.net/profile/Liandong-Yang


教育经历
2006.9-2010.6 安徽师范大学 生物科学专业 本科
2010.9-2015.6 中国科学院大学 水生生物学专业博士（硕博连读）
2013.10-2014.10 多伦多大学生物信息学专业 联合培养博士


主要职历
2015.9-2019.12 中国科学院水生生物研究所 助理研究员
2019.12-至今 副研究员


招生专业
动物学（硕士生）


研究方向
1.鱼类系统发育基因组学
2.鱼类进化基因组学
3.鱼类适应性进化


承担项目情况
2021.1-2023.7 东亚特有鲤科鱼类辐射分化的遗传基础，200万元，中国科学院战略性先导科技专项（B类）子课题，主持
2021.1-2024.12 中国科学院青年创新促进会会员，80万元，主持
2021.9-2022.8 东亚特有鲤科鱼类适应性进化研究，10万元，淡水生态与生物技术国家重点实验室开放课题，主持
2020.1-2023.12 青藏高原鱼类物种网状进化及高原适应的遗传基础：以高原鳅为例，75.4万元，国家自然科学基金委员会面上项目，主持
2018.1-2019.12 裂腹鱼类适应青藏高原极端环境的分子机制，8万元，中国科学院水生生物研究所青年人才项目，主持
2017.1-2019.12 裂腹鱼类基因组多倍化及其对青藏高原极端环境的适应机制研究，22.8万元，国家自然科学基金委员会青年科学基金项目，主持
2015.7-2018.12 斑马鱼中新基因的功能研究，30万元，中国科学院水生生物研究所特色所自由探索，主持


科研成果
　　十多年来一直以鱼类为研究对象，在鱼类基因组进化和适应辐射领域取得了系列研究进展。包括：1)共同发起万种鱼类基因组计划，搭建了鱼类整合基因组数据库;2)通过整合多种组学数据，发现基部辐鳍鱼类已经具备从水生到陆生适应的重要基因功能元件;3)发现变温动物鱼类适应青藏高原极端环境的遗传基础，证实生物高原适应的趋同现象;4)揭示骨鳔鱼类适应淡水环境的分子机制。以第一或通讯作者(含共同)发表研究论文22篇，包括2篇Cell，4篇Genome Biology and Evolution，2篇Molecular Ecology Resources，1篇GigaScience，1篇Communications Biology等，获得2020年度湖北省自然科学奖一等奖。主持2项国家自然科学基金、1项中国科学院先导专项子课题、入选中国科学院青年创新促进会会员，受邀担任国际期刊Frontiers in genetics的客座主编，负责组建编辑团队发起“生物适应极端环境的遗传机制”的主题专刊。
　　代表性论文：
1. Xupeng Bi^#, Kun Wang^#, Liandong Yang^#, Hailin Pan^#, Haifeng Jiang^#, Qiwei Wei^#, Miaoquan Fang, Hao Yu, Chenglong Zhu, Yiran Cai, Yuming He, Xiaoni Gan, Honghui Zeng, Daqi Yu, Youan Zhu, Huifeng Jiang, Qiang Qiu, Huanming Yang, Yong E. Zhang, Wen Wang*, Min Zhu*, Shunping He*, and Guojie Zhang*, Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes. Cell, 2021, 184 (5), 1377-1391
2. Kun Wang^#, Jun Wang^#, Chenglong Zhu^#, Liandong Yang^#, Yandong Ren^#, Jue Ruan^#, Guangyi Fan^#, Jiang Hu^#, Wenjie Xu, Xupeng Bi, Youan Zhu, Yue Song, Huatao Chen, Tiantian Ma, Ruoping Zhao, Haifeng Jiang, Bin Zhang, Chenguang Feng, Yuan Yuan, Xiaoni Gan, Yongxin Li, Honghui Zeng, Qun Liu, Yaolei Zhang, Feng Shao, Shijie Hao, He Zhang, Xun Xu, Xin Liu, Depeng Wang, Min Zhu, Guojie Zhang, Wenming Zhao*, Qiang Qiu*, Shunping He*, and Wen Wang*, African lungfish genome sheds light on the vertebrate water-to-land transition. Cell, 2021, 184 (5), 1362-1376
3. Yu Deng^#, Minghui Meng^#, Jian Fang, Haifeng Jiang, Ning Sun, Wenqi Lv, Yi Lei, Cheng Wang, Jing Bo, Chun Liu, Ying Wang*, Liandong Yang*, and Shunping He*, Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life. Molecular Ecology Resources, 2021
4. Jianbo Jian^#, Liandong Yang^#, Xiaoni Gan^#, Bin Wu^#, Li Gao, Honghui Zeng, Xuzhen Wang, Zhiqiang Liang, Ying Wang, Lihua Fang, Jie Li, Sanjie Jiang, Kang Du, Beide Fu, Mingzhou Bai, Ming Chen, Xiaodong Fang, Huanzhang Liu & Shunping He*, Whole genome sequencing of silver carp (Hypophthalmichthys molitrix) and bighead carp (Hypophthalmichthys nobilis) provide novel insights into their evolution and speciation. Molecular Ecology Resources, 2021, 21(3):912-923
5. Ying Wang and Liandong Yang*, Genomic evidence for convergent molecular adaptation in electric fishes. Genome biology and evolution, 2021, 13: 3
6. Wenqi Lv, Yi Lei, Yu Deng, Ning Sun, Xin Liu, Liandong Yang*, and Shunping He*, Accelerated evolution and positive selection of rhodopsin in Tibetan loaches living in high altitude. International Journal of Biological Macromolecules, 2020, 165, 2598-2606
7. Liandong Yang, Zetan Xu, Honghui Zeng, Ning Sun, Baosheng Wu, Cheng Wang, Jing Bo, Lin Li, Yang Dong, and Shunping He*, FishDB: an integrated functional genomics database for fishes. BMC Genomics, 2020, 21: 1
8. Guangyi Fan^#, Yue Song^#, Liandong Yang^#, Xiaoyun Huang, Suyu Zhang, Mengqi Zhang, Xianwei Yang, Yue Chang, He Zhang, Yongxin Li, Shanshan Liu, Lili Yu, Jeffery Chu, Inge Seim, Chenguang Feng, Thomas J Near, Rod A Wing, Wen Wang, Kun Wang, Jing Wang, Xun Xu, Huanming Yang, Xin Liu, Nansheng Chen, and Shunping He*, Initial data release and announcement of the 10,000 Fish Genomes Project (Fish10K). GigaScience, 2020, 9 (8), 1-8
9. Wenqi Lv, Haifeng Jiang, Jing Bo, Cheng Wang, Liandong Yang*, and Shunping He*, Comparative mitochondrial genome analysis of Neodontobutis hainanensis and Perccottus glenii reveals conserved genome organization and phylogeny. Genomics, 2020, 112, 3862–3870
10. Ying Wang, Haifeng Jiang, and Liandong Yang*, Transcriptome Analysis of Zebrafish Olfactory Epithelium Reveal Sexual Differences in Odorant Detection. Genes, 2020, 11, 592
11. Juan Chen, Yanjun Shen, Jing Wang, Gang Ouyang, Jingliang Kang, Wenqi Lv, Liandong Yang*, and Shunping He*, Analysis of multiplicity of hypoxia-inducible factors in the evolution of Triplophysa fish (Osteichthyes: Nemacheilinae) reveals hypoxic environments adaptation to Tibetan plateau. Frontiers in genetics, 2020, 11: 433
12. Juan Chen^#, Liandong Yang^#, Renyi Zhang, Cunfang Zhang, Haifeng Jiang, Yi Lei, Wenqi Lv, Fei Tian*, Kai Zhao*, and Shunping He*, Transcriptome-wide patterns of the genetic and expression variation in two sympatric schizothoracine fishes in a Tibetan Plateau glacier lake. Genome biology and evolution, 2020, 12: 3725-3737
13. Liandong Yang^#, Haifeng Jiang^#, Juan Chen, Yi Lei, Ning Sun, Wenqi Lv, Thomas J. Near*, and Shunping He*, Comparative genomics reveals accelerated evolution of fright reaction genes in Ostariophysan fishes. Frontiers in genetics, 2019, 10: 1283
14. Haifeng Jiang, Kang Du, Xiaoni Gan, Liandong Yang*, Shunping He*, Massive loss of olfactory receptors but not trace amine-associated receptors in the world’s deepest-living fish (Pseudoliparis swirei). Genes, 2019, 10: 910
15. Liandong Yang, Ying Wang, Tai Wang, Shengchang Duan, Yang Dong, Yanping Zhang, Shunping He*, A Chromosome-Scale Reference Assembly of a Tibetan Loach, Triplophysa siluroides. Frontiers in genetics, 2019, 10: 991
16. Liandong Yang, Haifeng Jiang, Ying Wang, Yi Lei, Juan Chen, Ning Sun, Wenqi Lv, Cheng Wang, Thomas J. Near*, and Shunping He*, Expansion of vomeronasal receptor genes (OlfC) in the evolution of fright reaction in Ostariophysan fishes. Communications Biology, 2019, 2:235
17. Liandong Yang, Zhaolei Zhang, Shunping He*, Both Male-Biased and Female-Biased Genes Evolve Faster in Fish Genomes. Genome biology and evolution, 2016, 8: 3433-3445
18. Liandong Yang, Ying Wang, Zhaolei Zhang, Shunping He*, Comprehensive transcriptome analysis reveals accelerated genic evolution in a Tibet fish, Gymnodiptychus pachycheilus. Genome biology and evolution, 2015, 7: 251-261
19. Liandong Yang, Zhaolei Zhang, Shunping He*, Bichir microRNA repertoire suggests a ray-finned fish affinity of Polypteriforme. Gene, 2015, 566: 242-247
20. Liandong Yang, David M. Irwin, Shunping He*, Genome-wide identification and characterization of teleost-specific microRNAs within zebrafish. Gene, 2015, 561: 181-189
21. Liandong Yang, Shunping He*, A bioinformatics-based update on microRNAs and their targets in rainbow trout (Oncorhynchus mykiss). Gene, 2014, 533: 261-269
22. Liandong Yang, Ming Zou, Beide Fu, Shunping He*, Genome-wide identification, characterization, and expression analysis of lineage-specific genes within zebrafish. BMC Genomics, 2013, 14: 65


获奖及荣誉
2021年度中国科学院青年创新促进会会员
2020年度湖北省自然科学奖一等奖（排名4/4）
2020年度水生所突出学术贡献奖优秀创新奖（排名2/3）
2015年度中国科学院院长优秀奖
2015年度国科大优秀毕业生
2013年度博士研究生国家奖学金
2013年度“中国科学院武汉教育基地昌华奖学金暨武汉分院院长奖学金”优秀奖


社会任职
湖北省动物学会常务理事兼秘书长
Frontiers in genetics期刊客座主编


备注
欢迎有生物学，计算机，基因组学背景的考生报考