姓 名:
　缪炜 性 别:
　男
职 称:
　研究员 学 历:
　博士
电 话:
　86-** 电子邮件:
　miaowei@ihb.ac.cn

简历：
缪炜，男，1974年5月生。中国科学院水生生物研究所研究员、博士生导师，原生动物功能基因组学学科组PI；中国动物学会理事，原生动物学分会理事、秘书长，亚洲原生生物学大会委员会委员，Tetrahymena Research Advisory Committee当然委员。

1996年和1999年在武汉大学分获学士学位和硕士学位；2002年于中国科学院水生生物研究所获博士学位，遂留所工作；2003年6月和2009年8月先后晋升为副研究员和研究员。2004年7月至2005年1月和2007年1月至2008年12月以高级访问学者身份分别在美国加洲大学圣巴巴拉分校Orias教授实验室和罗切斯特大学Gorovsky教授实验室开展合作研究。

2002以来，先后发表了40余篇学术论文；主持了国家自然科学基金重大研究计划、国家国际合作专项等一批科研项目；招收培养了10余名博士生和硕士生；与美国、奥地利、意大利、德国、日本和加拿大的多个实验室建立了长期合作；主持建立了四膜虫功能基因组学数据库（Tetrahymena Functional Genomics Database，TetraFGD，http://tfgd.ihb.ac.cn/）。2009年中国动物学会青年科技奖获得者，2010年武汉市学科带头人获得者，2011年湖北省自然科学基金杰出青年人才项目获得者。

研究方向：
1）原生动物进化基因组学与系统发育学；2）四膜虫进化与生态功能基因组学；3）四膜虫表观基因组学；4）四膜虫基因工程

专家类别：


职务：


社会任职：


获奖及荣誉：

代表论著：
（1）Feng J, Xiong J, Zhang J, Yang Y, Yao B, Zhou Z*, Miao W*. 2014. New Phylogenomic and Comparative Analyses Provide Corroborating Evidence that Myxozoa is Cnidaria. Molecular Phylogenetics and Evolution, 80: online

（2）Chang Y, Liu G, Guo L, Liu H, Yuan D, Xiong J, Ning Y, Fu C, Miao W*. 2014. Cd-Metallothioneins in Three Additional Tetrahymena Species: Intragenic Repeat Patterns and Induction by Metal Ions. J Eukaryot Microbiol, 61(4): 333-342.

（3）Feng L, Fu C, Yuan D, Miao W*. 2014. A P450 gene associated with robust resistance to dichlorodiphenyltrichloroethane (DDT) in ciliated protozoan, Tetrahymena thermophila by efficient degradation. Aquatic Toxicology, 149(3): 126-132.

（4）Ye J, Chang Y, Yan Y, Xiong J, Xue X, Yuan D, Sun G, Zhu Y*, Miao W*. 2014. Identification and characterization of the arsenite methyltransferase from a protozoan, Tetrahymena pyriformis. Aquatic Toxicology, 149(2): 50-57.

（5）Tian M, Chen X, Xiong Q, Xiong J, Xiao C, Ge F*, Yang* F, Miao W*. 2014. Phosphoproteomic Analysis of Protein Phosphorylation Networks in Tetrahymena thermophila, a Model Single-celled Organism. Molecular & Cellular Proteomics, 13(2): 503-19.

（6）Gao S, Xiong J, Zhang C, Berquist B, Yang R, Zhao M, Molascon A, Kwiatkowski S, Yuan D, Qin Z, Wen J, Kapler G, Andrews P, Miao W*, Liu Y*. 2013. Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & Devolpment, 27(15): 1662-79.

（7）Cervantes M,Hamilton E,Xiong J,Lawson M,Yuan D,Hadjithomas M,Miao W*,Orias E*. 2013. Selecting One of Several Mating Types through Gene Segment Joining and Deletion in Tetrahymena thermophila. PLoS Biology, 11(3): e**.

（8）Xiong J,Lu Y,Feng J,Yuan D,Tian M,Chang Y,Fu C,Wang G,Zeng H*,Miao W*. 2013. Tetrahymena functional genomics database (TetraFGD): an integrated resource for Tetrahymena functional genomics. Database(Oxford), bat008

（9）Xiong J, Lu XY, Zhou ZM, Chang Y, Yuan DX, Tian M, Zhou ZG, Wang L, Fu CJ, Orias E, Miao W*. 2012. Transcriptome Analysis of the Model Protozoan, Tetrahymena Thermophila, Using Rna-Seq [J]. PLoS One, 7(2): e30630.

（10) Xiong J, Yuan D, Fillingham JS, Garg J, Lu X, Chang Y, Liu Y, Fu C, Pearlman RE, Miao W*. 2011. Gene Network Landscape of the Ciliate Tetrahymena Thermophila [J]. PLoS One, 6(5): e20124.

（11）Chang Y, Feng LF, Miao W*. 2011. Toxicogenomic Investigation of Tetrahymena Thermophila Exposed to Dichlorodiphenyltrichloroethane (DDT), Tributyltin (TBT), and 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) [J]. Sci China Life Sci, 54(7): 617-625.

（12）Xiong J, Lu X, Lu Y, Zeng H, Yuan D, Feng L, Chang Y, Bowen J, Gorovsky M, Fu C, Miao W*. 2011. Tetrahymena Gene Expression Database (TGED): A Resource of Microarray Data and Co-Expression Analyses for Tetrahymena [J]. Sci China Life Sci, 54(1): 65-67.

（13）Liu Y, Zhou Z, Miao W, Zhang Y, Cao Y, He S, Bai D, Yao B. 2011. A Chitinase from Aeromonas Veronii Cd3 with the Potential to Control Myxozoan Disease [J]. PLoS One, 6(12): e29091.

（14）Xiong J, Feng L, Yuan D, Fu C, Miao W*. 2010. Genome-Wide Identification and Evolution of Atp-Binding Cassette Transporters in the Ciliate Tetrahymena Thermophila: A Case of Functional Divergence in a Multigene Family [J]. BMC Evol Biol, 10: 330.

（15）Fu C, Xiong J, Miao W*. 2009. Genome-Wide Identification and Characterization of Cytochrome P450 Monooxygenase Genes in the Ciliate Tetrahymena Thermophila [J]. BMC Genomics, 10:208.

（16）Miao W*, Xiong J, Bowen J, Wang W, Liu Y, Braguinets O, Grigull J, Pearlman RE, Orias E, Gorovsky MA*. 2009. Microarray Analyses of Gene Expression During the Tetrahymena Thermophila Life Cycle [J]. PLoS One, 4(2): e4429.

（17）Guo L, Fu C, Miao W*. 2008. Cloning, Characterization, and Gene Expression Analysis of a Novel Cadmium Metallothionein Gene in Tetrahymena Pigmentosa [J]. Gene, 423(1): 29-35.

（18）Feng LF, Miao W*, Wu YX. 2007. Difterentially Expressed Genes of Tetrahymena Thermophila in Response to Tributyltin (TBT) Identified by Suppression Subtractive Hybridization and Real Time Quantitative Pcr [J]. Aquatic Toxicology, 81(1): 99-105.

（19）Fu CJ, Miao W*. 2006. Cloning and Characterization of a New Multi-Stress Inducible Metallothionein Gene in Tetrahymena Pyriformis [J]. Protist, 157(2): 193-203.

（20）Miao W*, Yu T, Orias E, Wan ML, Fu CJ. 2006. Identification of Differentially Expressed Genes in Tetrahmena Thermophila in Response to Dichlorodiphenyltrichloroethane (DDT) by Suppression Subtractive Hybridization [J]. Environmental Microbiology, 8(6): 1122-1129.

（21）Miao W, Fen WS, Yu YH, Zhang XY, Shen YF. 2004. Phylogenetic Relationships of the Subclass Peritrichia (Oligohymenophorea, Ciliophora) Inferred from Small Subunit rRNA Gene Sequences [J]. J Eukaryot Microbiol, 51(2): 180-186.

（22）Miao W, Yu YH, Shen YF, Zhang XY. 2004. Intraspecific Phylogeography of Carchesium Polypinum (Peritrichia, Ciliophora) from China, Inferred from 18s-ITS1-5.8s Ribosomal DNA [J]. Sci China Ser C, 47(1): 11-17.

　　*：通讯作者（corresponding Author）