职称 副教授
邮箱 zhouyang@mail.hzau.edu.cn
研究方向 水生动物细菌病原的致病机理及免疫逃逸机制，同时开展病原菌诊断及免疫防治研究
教育经历
2005/9-2009/7 华中农业大学，生命科学技术学院，生物技术，学士
2012/5-2013/3 美国蒙大拿州立大学，免疫与传染病，联合培养博士
2009/9-2013/6 华中农业大学，动物医学院，预防兽医学，博士
主要职历
2013/10-2015/11 华中农业大学，水产学院，博士后
2015/12-2017/05 University of Florida, Postdoctoral Associate
2015/11-至今 华中农业大学，水产学院，副教授，硕士生导师
科研成果
（一）研究兴趣：
1. 水生动物细菌性病原致病机制；
2. 水生动物细菌性病原疫苗；
3. 细菌耐药性机制。
（二）近5年主持的科研项目：
1. 国家自然科学基金面上项目（**），2018/01-2021/12
2. 国家自然科学基金青年项目（**），2015-2017
3. 中国博士后科学基金面上一等资助（2014M550400），2014-2016
4. 中国博士后科学基金特别资助（2015T80819），2015-2017
5. 淡水生态与生物技术国家重点实验室开放课题（2015FB05），2015
6. 农业部渔用药物创制重点实验室开放课题（201306），2014-2016
（三）发表文章(*corresponding author)
1.Zhou Y, Dong X, Li Z, Zou G, Lin L, Wang X, Chen H, Gasser RB, Li J.Predominance ofStreptococcus suisST1 and ST7 in human cases in China, and detection of a novel sequence type, ST658.Virulence. 2016 Sep 30:1-5SCI IF: 5.4
2. Ji Y, Li J, Qin Z, Li A, Gu Z, Liu X, Lin L,Zhou Y*. Contribution of nuclease to the pathogenesis ofAeromonas hydrophila. Virulence, 6(5):515-22, 2015,SCI IF: 5.4
3. Zheng F, Asim M, Lan J, Zhao L, Wei S, Chen N, Liu X,Zhou Y*, Lin L*. Molecular Cloning and Functional Characterization of Mannose Receptor in Zebra Fish (Danio rerio) during Infection withAeromonas sobria. Int J Mol Sci, 16(5):10997-1012, 2015,SCI IF: 3.3
4. Liu X, Tang X, Wang L, Li J, Wang H, Wei S, Fang R, Ji W, Yuan G, Chen N, Gu Z, Liu X, Wang W, Asim M,Zhou Y*, Lin L*. Molecular cloning and expression analysis of mannose receptor in blunt snout bream (Megalobrama amblycephala). Molecular Biology Reports, 41(7):4601-11, 2014,SCI IF: 2.5
5.Zhou Y, Hanks TS, Feng W, Li J, Liu G, Liu M, Lei B*, The sagA/pel locus does not regulate the expression of the M protein of the M1T1 lineage of group AStreptococcus,Virulence, 4(8):698-706, 2013,SCI IF: 5.4
6.Zhou Y, Li L, Chen Z, Yuan H, Chen H, Zhou R*, Adhesion protein ApfA ofActinobacillus pleuropneumoniaeis required for pathogenesis and is a potential target for vaccine development, Clin Vaccine Immunol, 20(2), 287-94, 2013,SCI IF: 2.5
7. Dong X, Qin Z, Hu X, Lan J, Yuan G, Asim M,Zhou Y, Ai T, Mei J, Lin L*. Molecular cloning and functional characterization of cyclophilin A in yellow catfish (Pelteobagrus fulvidraco). Fish Shellfish Immunol, 45(2):422-430, 2015,SCI IF: 3.0
8. Wang W, Asim M, Yi L, Hegazy AM, Hu X,Zhou Y, Ai T, Lin L*. Abortive infection of snakehead fish vesiculovirus in ZF4 cells was associated with the RLRs pathway activation by viral replicative intermediates. Int J Mol Sci, 16(3):6235-50, 2015, SCI IF: 2.8
9. Zhao X, Liu L, Hegazy A, Wang H, Li J, Zheng F,Zhou Y, Wang W, Li J, Liu X*, Lin L*. Mannose receptor mediated phagocytosis of bacteria in macrophages of blunt snout bream (Megalobrama amblycephala) in a Ca2+-dependent manner. Fish and Shellfish Immunology, 43(2):357-63. 2015,SCI IF: 3.0
10. Liu L, Zhu B, Wu S, Lin L, Liu G,Zhou Y, Wang W, Asim M, Yuan J, Li L, Wang M, Lu Y, Wang H, Cao J, Liu X*. Spring Viremia of Carp Virus Induces Autophagy for Necessary Viral Replication. Cell Microbiol, 17(4):595-605, 2015,SCI IF: 4.9
11. Zhou W, Zhang Y, Wen Y, Ji W,Zhou Y, Ji Y, Liu X, Wang W, Asim M, Liang X*, Ai T*, Lin L*. Analysis of the transcriptomic profilings of Mandarin fish (Siniperca chuatsi) infected withFlavobacterium columnarewith an emphasis on immune responses. Fish and Shellfish Immunology, 43(1):111-9, 2015,SCI IF: 3.0
12. Xu W, Qin Z, Shi H, Jiang N,Zhou Y, Liu X, Xie J, Wang G, Wang W, Asim M, Zeng L, Lin L*. Mass mortality associated with a viral-induced anaemia in cage-reared large yellow croaker,Larimichthys crocea(Richardson). Journal of Fish Diseases, 38(5):499-502, 2015,SCI IF: 2.0
13. Liu X, Huang J, Weng S, Hu X, Chen W, Qin Z, Dong X, Liu X,Zhou Y, Asim M, Wang W, He J, Lin L*. Infections of nervous necrosis virus in wild and cage-reared marine fish from South China Sea with unexpected wide host ranges. J Fish Dis, 38(6):533-40, 2015,SCI IF: 2.0
14. Liu L,Zhou Y, Zhao X, Wang H, Wang L, Yuan G, Asim M, Wang W, Zeng L, Liu X, Lin L. Oligochitosan stimulated phagocytic activity of macrophages from blunt snout bream (Megalobrama amblycephala) associated with respiratory burst coupled with nitric oxide production. Dev Comp Immunol, 47(1):17-24, 2014,SCI IF: 3.7
15. Li J, Liu G, Feng W,Zhou Y, Liu M, Wiley JA, Lei B*, Neutrophils select hypervirulent CovRS mutants of M1T1 group AStreptococcusduring subcutaneous infection of mice, Infect Immun, 82(4):1579-90, 2014,SCI IF: 4.2
16. Wang L, Liu L,Zhou Y, Zhao X, Xi M, Wei S, Fang R, Ji W, Chen N, Gu Z, Liu X, Wang W, Asim M, Liu X*, Lin L*, Molecular cloning and expression analysis of mannose receptor C type 1 in grass carp (Ctenopharyngodonidella), Dev Comp Immunol, 43(1):54-8, 2014,SCI IF: 3.7
17. Li J, Zhu H, Feng W, Liu M, Song Y, Zhang X,Zhou Y, Bei W, Lei B*, Regulation of inhibition of neutrophil infiltration by two-component regulatory system CovRS in subcutaneous mouse infection with Group AStreptococcus,Infect Immun, 81(3):974-83, 2013,SCI IF: 4.2
18. Li L, Xu Z,Zhou Y, Sun L, Liu Z, Chen H, Zhou R*,Global effects of catecholamines onActinobacillus pleuropneumoniaegene expression, PLoS ONE, 7(2): e31121, 2012,SCI IF: 3.7
19. Li J, Xia J, Tan C,Zhou Y, Wang Y, Zheng C, Chen H, Bei W*, Evaluation of the immunogenicity and the protective efficacy of a novel identified immunogenic protein, SsPepO, ofStreptococcus suisserotype 2, Vaccine, 29(38):6514-9, 2011,SCI IF: 3.6
20. Li L, Xu Z,Zhou Y, Li T, Sun L, Chen H, Zhou R*, Analysis onActinobacillus pleuropneumoniaeLuxS regulated genes reveals pleiotropic roles of LuxS/AI-2 on bio?lm formation, adhesion ability and iron metabolism, Microb Pathogenesis, 50(6): 293-302, 2011SCI IF: 2.0
21. Li J, Tan C,Zhou Y, Fu S, Hu L, Hu J, Chen H, Bei W*, The two-component regulatory system CiaRH contributes to the virulence ofStreptococcus suis2,Vet Microbiol, 148(1):99-104, 2011SCI IF: 3.3
备注
欢迎对水生动物细菌病害与免疫感兴趣的学生加盟。