殷平 【教授】 姓名殷平性别男
职称教授学位博士
电话 **邮箱yinping@mail.hzau.edu.cn
工作单位华中农业大学生命科学技术学院
研究方向结构生物学；植物发育调控蛋白的结构与功能；RNA识别工具开发
教育经历2006/09-2009/06武汉大学，生命科学学院生物化学系，博士
2003/09-2006/06武汉大学，生命科学学院生物化学系，硕士
1999/09-2003/06武汉大学，生命科学学院生物技术系，学士

主要职历2013.09?PresentProfessor
SchoolofLifeSciencesandTechnology,NationalkeyLaboratoryofCropGeneticImprovement,HuazhongAgriculturalUniversity,Wuhan,P.R.China.

2009.07?2013.08PostdoctoralFellow
CenterofStructuralBiology,SchoolofLifeSciences,TsinghuaUniversity,Beijing,P.R.China.




科研成果




1) PPR

Yin P^*, Li Q^*, Yan C, Liu Y, Liu J, Yu F,Wang Z, Long J, He J, Wang H, Wang J, Zhu J, Shi Y, Yan N. Structural basis forthe modular recognition of single-stranded RNA by PPR proteins. Nature 2013 Dec 5; 504 (7478): 168-171. (Equal contribution)

Li Q, Yan C, Xu H, Wang Z, LongJ, LiW, Wu J, Yin P^#, YanN^#. Examination ofthe dimerization states of the single-stranded RNA-recognition protein PPR10. JBiol Chem. 2014 Nov 7; 289 (45):31503-12. (#Corresponding Author)



Shen C, Wang X, Liu Y, Li Q, Yang Z, Yan N, Zou T, Yin P^#. Specific RNA Recognition by Designer Pentatricopeptide RepeatProtein. Mol Plant. 2015 Jan 7. [Epub ahead of print] (#CorrespondingAuthor)



2) ABAreceptor



Yin P^*, Fan H^*, Hao Q^*,Yuan X^*, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N. Structuralinsights into the mechanism of abscisicacid signaling by PYL proteins. NatStruct Mol Biol. 2009 Dec; 16 (12): 1230-6. (Equalcontribution) (Cover Paper)(Breakthrough of the year in Science )

Hao Q^*, Yin P^*, Li W, Wang L, Yan C, Lin Z, Wu JZ, Wang J, Yan SF,Yan N. The molecular basis of ABA-independent inhibition of PP2Cs by a subclassof PYL proteins. Mol Cell. 2011 Jun 10;42(5):662-72. (Equal contribution)



Yuan X^*, Yin P^*, Hao Q^*, Yan C, Wang J, Yan N.Single amino acid alteration between valine and isoleucine determines thedistinct pyrabactin selectivity by PYL1 and PYL2. J Biol Chem. 2010 Sep 10;285 (37): 28953-8. (Equal contribution)

Hao Q^*, Yin P^*, Yan C^*, Yuan X, Li W, Zhang Z, LiuL, Wang J, Yan N. Functional mechanism of the abscisic acid agonist pyrabactin. JBiol Chem. 2010 Sep 10; 285 (37): 28946-52. (Equal contribution)



Li W,Wang L, Sheng X, Yan C, Zhou R, Hang J, YinP, Yan N. Molecular basis for the selective and ABA-independent inhibitionof PP2CA by PYL13. Cell Research. 2013 Dec;23(12):1369-79.



He Y,Hao Q, Li W, Yan C, Yan N^#, YinP^#. Identificationand characterization ofABAreceptors in Oryza sativa. PloSONE. 2014 Apr 17; 9(4): e95246. (#CorrespondingAuthor)



3) TAL effector (TALE)



Yin P*, Deng D*, Yan C,Pan X, Xi J, Yan N, Shi Y. Specific DNA-RNA hybrid recognition by TALeffectors. Cell Reports. 2012 Oct 25; 2 (4):707-13. (Equal contribution) (The Best of Cell Reports in 2012)
DengD*, Yin P*, Yan C, Pan X, Gong X, QiS, Xie T, Mahfouz M, Zhu Jian-Kang, Yan N, Shi Y. Recognition of methylated DNAby TAL effectors. Cell Research. 2012 Oct; 22 (10):1502-4. (Equal contribution)



4) mRNA-splicing Prp19-associated complex

Lu P,Lu G, Yan C, Wang L, Li W and Yin P^#.Structure of the mRNA splicing complex component Cwc2: insights intoRNA-recognition. Biochem J. 2012 Jan 15;441(2):591-7. (#Corresponding Author)




5) Mechanism of plasmidstability



Yin P, Li TY, Xie MH,Jiang L, Zhang Y. A Type Ib ParB protein involved in plasmid partitioning in agram-positive bacterium. J Bacteriol. 2006 Dec; 188 (23):8103-8.

Li TY^*, Yin P^*, Zhou Y, Zhang Y, Zhang YY, Chen TA. Characterizationof the replicon of a 51-kb native plasmid from the gram-positive bacterium Leifsonia xyli subsp. cynodontis. FEMS Microbiol Lett. 2004Jul 1; 236 (1): 33-9. (Equalcontribution)

HuangL, Yin P, Zhu X, Zhang Y, Ye K.Crystal structure and centromere binding of the plasmid segregation proteinParB from pCXC100. Nucleic Acids Res. 2011 Apr 39; (7): 2954-68.

Li TY,Zeng HL, Yin P, Lin H, Fan XL, GuoZG, Zhang CF. Construction of a stable expression vector for Leifsonia xylisubsp. cynodontis and its application in studying the effect of the bacteriumas an endophytic bacterium in rice. FEMS Microbiol Lett. 2007 Feb; 267(2):176-83.




6) Others

Zhou L,Hang J, Zhou Y, Wan R, Lu G, Yin P,Yan C, Shi Y. Crystal structures of the Lsm complex bound to the 3' endsequence of U6 small nuclear RNA. Nature. 2014 Feb 6;506(7486):116-20.

Ma D,Lu P, Yan C, Fan C, Yin P, Wang J,Shi Y. Structure and mechanism of a glutamate-GABA antiporter. Nature.2012Mar 11;483(7391):632-6.





备注实验室在第二综合楼A102，欢迎对结构生物学有兴趣的学生加入！

本实验常年招收博士后。

---

CLST

---

---