首页 > 导师简介 > 病理学系
段雅琦

段亚琦 1976年出生，博士，副教授，硕士研究生导师。德国干细胞协会会员。1999年本科毕业于华中科技大学同济医学院，同年留校任教。2001.01-2005.05德国科隆大学攻读心血管生理专业博士，以优秀人才引进回华中科技大学同济医学院。现从事病理学教学、科研和临床诊断工作。




主要研究方向：心血管病理学；从事胚胎、成年心肌细胞及胚胎干细胞分化的心肌细胞、离子通道的表达、信号转导机制，胚胎干细胞移植的研究

科研工作：主持并完成国家自然科学基金青年基金（**）；现主持国家教委归国留学人员启动基金，武汉市晨光计划人才基金（**6）、教育部新世纪人才基金（NCET-07-0321）的资助开展相关研究；另参与多项国家自然科学基金项目。




个人作品：




1. Fleischmann BK, Duan Y, Fan Y, Schoneberg T, Ehlich A, Lenka N, Viatchenko-Karpinski S, Pott L, Hescheler J, Fakler B. Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development. J Clin Invest 2004 Oct;114(7):994-1001. 第一作者同等贡献




2．DUAN Ya-Qi. TANG Ming, LIANG Hua-Min, SONG Yuan-Long, LUO Hong-Yan, Jürgen. Hescheler. Investigation on spontaneous electrical activity of murine embryonic heart using microelectrode arrays. Acta Physiologica Sinica 2006 Feb 25;58(1):65-70




3. Kolossov E, Lu Z, Drobinskaya I, Gassanov N, Duan Y, Sauer H, Manzke O, Bloch W, Bohlen H, Hescheler J, Fleischmann BK. Identification and characterization of ES cell-derived pacemaker- and atrial cardiomyocytes. FASEB J. 2005 Apr; 19(6):577-9. Epub 2005 Jan 19.




4. Reppel M, Sasse P, Piekorz R, Tang M, Roell W, Duan Y, Kletke A, Hescheler J, Nurnberg B, Fleischmann BK. S100A1 Enhances the L-type Ca2+ Current in Embryonic Mouse and Neonatal Rat Ventricular Cardiomyocytes. J Biol Chem. 2005 Oct 28;280(43):36019-28. Epub 2005 Aug 28.




5．Frank Pillekamp , Michael Reppel, Vera Dinkelacker, Yaqi Duan, Nathalie Jazmati, Wilhelm Bloch, Konrad Brockmeier, Jürgen Hescheler, Bernd K. Fleischmann, Rüdiger K?hling. Establishment and characterization of heart slices from mouse embryos. Cell Physiol Biochem. 2005;16(1-3):127-32.




6．*Eugen Kolossov, * Toktam Bostani, *Wilhelm R?ll, *Martin Breitbach, Frank Pillekamp, Jens M. Nygren, Philipp Sasse, Olga Rubenchik, Jochen W. U. Fries, Daniela Wenzel, Caroline Geisen, Ying Xia, Zhongju Lu, Yaqi Duan, Ralf Kettenhofen, Stefan Jovinge, Wilhelm Bloch, Heribert Bohlen, Armin Welz, Juergen Hescheler, Sten Eirik Jacobsen, Bernd K. Fleischmann. Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium. JEM, Volume 203, Number 10, 2315-2327




7. Yan-Qiu Yu, Ya-Qi Duan, Yi-Xia Zhang, Ming Tang, J. Hesheler, Hai-Peng Zhang. Genes Expression and Electrophysiological Characterization of ES cell-derived Cardiomyocytes Chinese Journal of Pathophysiology. 2006 Vol.22 No.4 P.666-669




8. LI Jing, WANG Ming-Huan, WANG Le1;TIAN Yang, DUAN Ya-Qi, LUO Hong-Yan, HU Xin-Wu, Jüergen Hescheler, TANG Ming. Role of transient receptor potential vanilloid 4 in the effect of osmotic pressure on myocardial contractility in rat. Acta Physiologica Sinica; April 25, 2008, 60 (2): 181-188