肖波涛发布者：huake 发布时间：2013-11-07 23:13 浏览次数：次编辑
肖波涛，教授，美国西北大学博士，哈佛大学医学院Research Fellow。湖北人，本科毕业于重庆大学，硕士是中国科学院力学研究所和重庆大学联合培养的（课程在北京大学和清华大学完成），曾在美国伊利诺大学学习。主持和参与中国国家自然科学基金面上项目、美国国立卫生研究院、美国自然科学基金等多个项目。负责和参与研制过磁镊、激光光镊、生物膜力探针、脑肿瘤电磁成像等仪器，以通讯作者和第一作者在Nucleic Acids Res.、 Mol. Biol. Cell等杂志发表多篇论文，在多个国际国内会议做大会报告，获得多个奖项。研究方向涉及单分子仪器研发和精密测量、核酸组装和重组、多种疾病有关的蛋白质-配体相互作用、PM2.5与细胞的相互作用等。欢迎物理、力学、生物医学/光学/机械/电气工程等相关背景的人士加盟课题组。
Botao Xiao

Professor, Principal Investigator, Huazhong University of Science and Technology

PhD, Northwestern University (USA)

Research Fellow, Harvard Medical School (USA)

BXiao lab uses advanced physical tools to measure, manipulate, and visualize the movements of single molecules in order to solve compelling biomedical problems. The research includes single molecule instrumentation and measurements, nucleic acids organization and recombination, protein-ligand interactions, and PM2.5 and cell interactions.



Email: bxiao(at)hust.edu.cn or botaoxiao(at)gmail.com

Address: S509, School of Physics

Huazhong University of Science and Technology

1037 Luoyu Road, Wuhan, Hubei 430074, China

通讯地址: 湖北省武汉市珞喻路1037号，华中科技大学物理学院，邮编430074

科技楼南509
Selected publication:

B. Xiao*, B.S. Freedman, R. Heald, and J. F. Marko. Histone H1 compacts DNA under force and during chromatin assembly, Mol. Biol. Cell, 23, 4864-71, 2012
B. Xiao, C. Tong, X. Jia, R. Guo, S. Lü, Y. Zhang, R.P. McEver, C. Zhu, and M. Long. Tyrosine Replacement of PSGL-1 Reduces Association Kinetics with P- and L-Selectin on the Cell Membrane, Biophys. J., 103, 777-85, 2012
B. Xiao*, H. Zhang, R.C. Johnson, and J.F. Marko. Force-driven unbinding of proteins HU and Fis from DNA quantified using a thermodynamic Maxwell relation, Nucleic Acids Res., 39, 5568-77, 2011
B. Xiao*, R.C. Johnson, and J.F. Marko. Modulation of HU-DNA interactions by salt concentration and applied force, Nucleic Acids Res., 38, 6176-85, 2010
L. Wu^, B. Xiao^, X. Jia, Y. Zhang, S. Lü, J. Chen, and M. Long. Impact of carrier stiffness and microtopology on two-dimensional kinetics of P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) interactions, J. Biol. Chem., 282, 9846-54, 2007