一、基本信息
李圣纯，博士，副教授，博士生导师
办公电话：-8069
电子邮件：shengchun_li(at)163.com
研究领域：质体（叶绿体）基因工程，植物氧化还原信号转导
二、教育背景
2009.03–2013.07 法国巴黎十一大学植物研究所，理学博士
2011.04–2011.05 英国利兹大学生物科学学院，访问研究
2008.09–2009.01 中国科学院武汉病毒所，博士研究生（无学位）
2006.09–2008.07 华中科技大学生命科学与技术学院，理学硕士
2002.09–2006.07 武汉轻工大学生命科学与技术学院，工学学士
三、工作经历
2017.07至今 湖北大学生命科学学院，副教授
2015.07–2017.06 湖北大学生命科学学院，讲师
2014.07–2015.05 武汉生命之美科技有限公司，部门主管
2013.10–2014.06 中国农业科学院作物研究所，林辰涛教授课题组，访问研究
四、科研项目
1. 国家自然科学基金面上基金（**）：氧化应激增强质体介导RNAi抗棉铃虫效果的分子机制及应用研究，58万元，2021.01–2024.12，主持
2. 国家自然科学基金青年基金（**）：PP2A-B'γ在过氧化氢诱导的细胞死亡中的机理研究，23万元，2018.01–2020.12，主持
3. 湖北省人才项目，10万元，2017.07–2022.06，主持
4. 湖北大学启动基金（080/170039）：内源H₂O₂诱导拟南芥光照周期依赖性细胞死亡的分子机理研究，2万元，2016.01–2017.12，主持
五、发表论文（^#共同第一作者，^*通讯作者）
（一）第一或通讯作者论文
1. Li S, Chang L, Zhang J. (2021) Advancing organelle genome transformation and editing for crop improvement. Plant Communications 2, 100141.
2. Ding H, Wang B, Han Y, Li S*. (2020) Dehydroascorbate reductase, a pivotal regulator in ascorbate-glutathione pathway in plants. Journal of Experimental Botany 71, 3405–3416.
3. Zhang Y, Xu L, Li S*, Zhang J*. (2019) Bacteria-mediated RNA interference for management of Plagiodera versicolora (Coleoptera: Chrysomelidae). Insects 10, 415.
4. Wang B, Ding H, Chen Q, Ouyang L, Li S*, Zhang J*. (2019) Enhanced tolerance to methyl viologen-mediated oxidative stress via AtGR2 expression from chloroplast genome. Frontiers in Plant Science 10, 1178.
5. Chen Q, Wang B, Ding H, Zhang J*, Li S*. (2019) The role of NADP-malic enzyme in plants under stress. Plant Science 281, 206–212.
6. Rahantaniaina MS^#, Li S^#, Chatel-Innocenti G, Andrée Tuzet A, Issakidis-Bourguet E, Mhamdi A, Noctor G. (2017) Chloroplastic and cytosolic dehydroascorbate reductases co-operate in oxidative stress-driven activation of the salicylic acid pathway. Plant Physiology 174, 956–971.
7. Li S, Mhamdi A, Trotta A, Kangasj?rvi S, Noctor G (2014) The protein phosphatase subunit PP2A-B'γ is required to suppress daylength-dependent pathogenesis responses triggered by intracellular oxidative stress. New Phytologist 202, 145–160.
8. Li S, Mhamdi A, Dizengremel P, Jolivet Y, Noctor G. (2013) Analysis of knockout mutants suggests that Arabidopsis NADP-MALIC ENZYME2 does not play an essential role in determining phenotypes or regulating redox state in response to oxidative stress of intracellular or extracellular origin. Journal of Experimental Botany 64, 3605–3614.
（二）共同作者论文
1. Fu J, Xu W, Huang W, Wang B, Li S, Zhang J, Chang L. (2021) Importation of taxadiene synthase into chloroplast improves taxadiene production in tobacco. Planta 253, 107.
2. Xu S, Zhang Y, Li S, Chang L, Wu Y, Zhang J. (2020) Plastid-expressed Bacillus thuringiensis (Bt) cry3Bb confers high mortality to a leaf eating beetle in poplar. Plant Cell Reports 39, 317–323.
3. Zhang T, Ma M, Chen T, Zhang L, Fan L, Zhang W, Wei B, Zhang D, Li S, Xuan W, Noctor G, Han Y. (2020) Arabidopsis S-nitrosoglutathione reductase1 coordinates glutathione-mediated activation of salicylic acid pathway in response to intracellular oxidative stress. Plant Cell & Environment 43, 1175–1191.
4. Durian G, Jeschke V, Vuorinen K, Rahikainen M, Gollan P, Glawischnig E, Winter Z, Li S, Noctor G, Aro EM, Kangasj?rvi J, Overmyer K, Burow M, Kangasj?rvi S. (2020) Protein phosphatase 2A-B′γ controls Botrytis cinerea resistance and developmental leaf senescence. Plant Physiology 182, 1161–1181.
5. Wu Y, Xu L, Chang L, Ma M, You L, Jiang C, Li S, Zhang J. (2019) Bacillus thuringiensis (Bt) cry1C expression from the plastid genome of poplar leads to high mortality of leaf eating caterpillars. Tree Physiology 39, 1525–1532.
6. You L, Song Q, Wu Y, Li S, Jiang C, Chang L, Yang X, Zhang J. (2019) Accumulation of glycine betaine in transplastomic potato plants expressing choline oxidase confers improved drought tolerance. Planta 249, 1963–1975.
7. Wu Y, You L, Li S, Ma M, Wu M, Ma L, Bock R, Chang L, Zhang J. (2017) In vivo assembly in Escherichia coli of transformation vectors for plastid genome engineering. Frontiers in Plant Science 8, 1454.
8. Rahantaniaina MS, Li S, Chatel-Innocenti G, Tuzet A, Mhamdi A, Vanacker H, Noctor G. (2017) Glutathione oxidation in response to intracellular H₂O₂: key but overlapping roles for dehydroascorbate reductases. Plant Signaling & Behavior 12, e**.
9. Kangasj?rvi S, Neukermans J, Li S, Aro E, Noctor G. (2012) Photosynthesis, photorespiration, and light signalling in defence responses. Journal of Experimental Botany 63, 1619–1636.
10. Noctor G, Hager J, Li S. (2011) Biosynthesis of NAD and its manipulation in plants. Advances in Botanical Research 58, 153–201.
11. Gao J, Li J, Luo C, Yin L, Li S, Yang G, He G. (2010) Callus induction and plant regeneration in Alternanthera philoxeroides. Molecular Biology Reports 38, 1413–1417.
12. Ding L, Li S, Gao J, Wang Y, Yang G, He G. (2009) Optimization of Agrobacterium-mediated transformation conditions in mature embryos of elite wheat. Molecular Biology Reports 36, 29–36.