一、基本情况
孙丽娟，博士，副教授，硕士研究生导师
办公电话：
电子邮件：lijuansun1212@163.com
研究领域：细胞药理学、分子药理学
二、教育背景
2006.09–2010.03 华东理工大学药学院，获理学博士学位
2003.09–2006.07 湖北中医药大学药学系，获理学硕士学位
1999.09–2003.07 湖北中医药大学药学系，获理学学士学位
三、工作经历
2010.04至今 湖北大学生命科学学院，讲师、副教授
四、科研项目
1. 武汉市科技局青年晨光计划（5）：黄芪抗骨质疏松物质基础及其作用机理的研究，2011.01–2013.12，主持人
2. 湖北省教育厅优秀中青年人才项目（Q**）：黄芪抗骨质疏松物质基础及其作用机理研究, 2011.01–2013.12，主持人
3. 湖北省自然科学基金（2012FFB00303）：Withangulatin A 调节骨代谢作用机理的研究, 2013.01–2015.12，主持人
五、代表性论文
1. Sun L, Liu J, Cui D, Li J, Yu Y, Ma L, Hu L. (2009) Anti-inflammatoty of Withagulatin A via COX-2 through MAPK and NF-κB pathways. Journal of cellular biochemistry 109, 523–541.
2. Sun L, Liu J, Ma L, Li J, Yu Y, Hu L. (2011) Evaluation of immunosuppressive activity of Withangulatin A via ERK/MAPK pathway. Process Biochemistry. 2011, 46: 482–488.
3. Sun L, Zhou L, Liu J, Chen M. (2011) Amelioration of systemic lupus erythematosus by Withangulatin A in MRL/lpr Mice. Journal of cellular biochemistry 112, 2376–2382.
4. Sun L, Yu Y, Hu L, Liu J. (2008) Cell-immunosuppressive mechanism of X5 from Withania coagulans. 12th Asia Pacific Confederation of Chemical Engineering Congress, 2008. 08, I–P–026: 0388.
5. Zhou L, Sun L, Wu H, Zhang L, Chen M, Liu J, Zhong R. (2013) Oridonin ameliorates lupus-like symptoms of MRLlpr/lpr mice by inhibition of B-cell activating factor (BAFF). European Journal of Pharmacology 715, 230–237.
6. Yu Y, Sun L, Lei Ma L, Hu L, Liu J. (2010) Investigation of the immunosuppressive activity of Physalin H on T lymphocytes. International Immunopharmacology 10, 290–297.
7. Huang CF, Ma L, Sun L, Ali M. (2009) Immunosuppressive Withanolides from Withania coagulans. Chemistry & Biodiversity 6, 1415–1426.
8. Li J, Du J, Sun L, Liu J, Quan Z. (2010) The immune-suppressive effect of Nordosin via inhibition of IL-2. The American Journal of Chinese Medicine 38, 127–142.
9. Ye Y, Liu J, Xu J, Sun L, Chen M, Lan M. (2010) Nano-SiO₂ induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cells. Toxicology in Vitro 24, 751–758.
10. Ye Y, Liu J, Chen M, Sun L, Lan M. (2010) In vitro toxicity of silica nanoparticles in myocardial cells. Environmental Toxicology and Pharmacology 29, 131–137.
11. Chen M, Gu H, Ye Y, Lin B, Sun L, Deng W, Zhang J, Liu J. (2010) Protective effects of hesperidin against oxidative stress of tert-butyl hydroperoxide in human hepatocytes. Food and Chemical Toxicology. 48, 2980–2987.
六、专利
1. 马磊，刘建文，胡立宏，孙丽娟，于有军, 等. 含Withanolide型化合物的免疫抑制剂ZL3.0。
七、获奖
1. 2010年3月 荣获华东理工大学 蒋华良论文一等奖
2. 2008年10月 荣获华东理工大学 科研实践综合奖