张勇

Submitted on 周一, 10/30/2017 - 20:51


性别
男

工作电话


电子邮件
lsszy@mail.sysu.edu.cn

职称
教授

导师类型
博士生导师

学历
博士研究生

学科方向
0710生物学-04水生生物学


研究方向
水生经济动物繁殖与育种；水生经济动物重要生产性状的形成与控制

个人经历
1995年9月至1999年7月，中山大学生命科学学院生物化学系获理学学士学位
1999年9月至2004年7月，中山大学生命科学学院水生经济动物研究所获理学博士学位
2004年7月至2009年12月，中山大学生命科学学院水生经济动物研究所，讲师
2010年1月至2014年12月，中山大学生命科学学院水生经济动物研究所，副教授
2015年1月至今，??????? 中山大学生命科学学院水生经济动物研究所，教授
2016年5月至今，??????? 中山大学广东省水生经济动物良种繁育重点实验室，主任
2005年2月至2005年3月， 香港城市大学生物化学系访问****
2008年8月至2008年12月，香港中文大学生物化学系访问****
2011年7月至2012年1月， 加拿大约克大学生物系访问****

讲授课程
《生物安全》、《动物学实验》、《食品安全与日常生活》
《水生经济动物繁殖与育种》、《鱼类繁殖与育种》、《鱼类生理学》

学术成就
2004年获得理学博士学位，2008年获得中山大学硕士研究生导师资格，2010年1月聘为副教授，2015年1月聘为教授。从事水生经济动物繁殖和育种的研究工作，对水生经济动物重要生产性状的形成与控制开展研究。在水生经济动物繁殖机理方面，系统地分析了鱼类新型神经肽编码基因的在摄食调节和生殖调控中的功能，筛选出对鱼类性腺发育成熟、性别转换、排卵和产精、生长和发育起重要促进作用的功能基因。在水生经济动物优良品种培育方面，将传统育种技术与现代生物技术相结合，开展了家系选择育种，杂交育种和细胞工程育种研究，培育出了优良杂交新品种；建立了水生经济动物性别控制技术，构建了草鱼和石斑鱼全基因组精细图谱和高密度遗传连锁图谱，筛选出与表型性状存在显著关联的标记，应用于良种的分子选育，现已主持国家级项目5项、主持和参加省部级科研项目22项；已发表159篇SCI收录学术论文，其中第一或通讯作者60篇；申请专利42项，授权22项；获得教育部自然科学奖一等奖1项，教育部科技进步奖一等奖2项，广东省科技进步奖一等奖1项，广东省农业技术推广奖一等奖1项，全国农牧渔业丰收奖二等奖1项。
现任广东省水生经济动物良种繁育重点实验室主任；广东省青年科协常务理事；教育部高等学校水产类专业教学指导委员会委员；中国动物学会理事；中国动物学会比较内分泌学专业委员会秘书长；中国水产学会水产生物技术专业委员会委员；“领航100”广东亿元级青年领军企业实力提升计划“青年科技特派员”。

承担课题
1. 2018.12-2022.12，“金钱鱼/鳜鱼性别控制与单性苗种研制”，国家重点研发计划“蓝色粮仓科技创新”专项“重要养殖鱼类优良种质创制与生殖操作技术研究”项目“重要养殖鱼类基因组编辑与性别转换技术”子课题，课题编号：2018YFD**，125万元；
2. 2018.5-2021.4，“促性腺激素调控石斑鱼性别分化的分子机制”，广东省自然科学基金重点项目(2018B)，50万元；
3. 2020.1-2022.12，“翘嘴鳜性别决定的分子基础研究”，广东省基础与应用基础研究基金区域联合基金-重点项目(2019B)，100万元；
4. 2020.1-2023.12，“促卵泡激素FSH调控斜带石斑鱼性别分化的机制研究”，国家自然科学基金(**)，58万元；

论文专著
1. Wang Yaping, Lu Ying, Zhang Yong(共同第一作者), Ning Zemin, Li Yan, Zhao Qiang, Lu Hengyun, Huang Rong, Xia Xiaoqin, Feng Qi, Liang Xufang, Liu Kunyan, Zhang Lei, Lu Tingting, Huang Tao, Fan Danlin, Weng Qijun, Zhu Chuanrang, Lu Yiqi, Li Wenjun, Wen Ziruo, Zhou Congcong, Tian Qilin, Kang Xiaojun, Shi Mijuan, Zhang Wanting, Jang Songhun, Du Fukuan, He Shan, Liao Lanjie, Li Yongming, Gui Bin, He Huihui, Ning Zhen, Yang Cheng, He Libo, Luo Lifei, Yang Rui, Luo Qiong, Liu Xiaochun, Li Shuisheng, Huang Wen, Xiao Ling, Lin Haoran*, Han Bin*, Zhu Zuoyan*. The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation. Nature Genetics.2015,47(6):625-632;
2. Qi Xin, Zhou Wenyi, Li Shuisheng, Liu yun, Ye Gang, Liu Xiaochun, Peng Chun*, Zhang Yong*, Lin Haoran*. Goldfish neurokinin B: Cloning, tissue distribution, and potential role in regulating reproduction. General and Comparative Endocrinology. 2015, 221(15):267-277. (2015 Impact Factor: 2.667)
3. Yang Huirong, Chen Huapu, Zhao Huihong, Liu Li, Xie Zhenzhen, Xiao Ling, Li Shuisheng*, Zhang Yong*, Lin Haoran. Molecular cloning of the insulin-like growth factor 3 and difference in the expression of igf genes in orange-spotted grouper (Epinephelus coioides). Comparative Biochemistry and Physiology, Part B 2015,186: 68–75.
4. Xie Zhenzhen, Li Shuisheng, Yao Mi, Lu Danqi, Li Zhihao, Meng Zining, Zhang Yong*, Lin Haoran*. The complete mitochondrial genome of the Trachinotus ovatus (Teleostei, Carangidae).Mitochondrial DNA. 2015, 26(4):644-646.
5. Li Shuisheng, Xiao Ling, Liu Qiongyu, Zheng Binbin, Chen Huapu*, Liu Xiaochun, Zhang Yong*, Lin Haoran. Distinct functions of neuromedin u and neuromedin s in orange-spotted grouper. Journal of Molecular Endocrinology. 2015, 55(2), 95–106.
6. Sun Ying, Guo Chuanyu, Wang Dengdong, Li Xiaofeng, Xiao Ling, Zhang Xinhui, You Xinxin, Shi Qiong, Hu Guojun, Fang Chang, Lin Haoran*, Zhang Yong*. Transcriptome analysis reveals the molecular mechanisms underlying growth superiority in a novel grouper hybrid (Epinephelus fuscogutatus♀ × E. lanceolatus♂). BMC Genetics. 2016, 17:24.
7. Yu Hui, You Xinxin, Li Jia, Li Hankui, Meng Zining, Xiao Ling, Zhang Haifa, Lin Haoran*, Zhang Yong*, Shi Qiong*. Genome-Wide Mapping of Growth-Related Quantitative Trait Loci in Orange-Spotted Grouper (Epinephelus coioides) Using Double Digest Restriction-Site Associated DNA Sequencing (ddRADseq). International Journal of Molecular Sciences. 2016 (17), 501-512.
8. Wang Qing, Wang Xiang, Xie Zhenzhen, Li Yiqi, Xiao Ling, Peng Cheng, Zhang Haifa, Li Shuisheng, Zhang Yong*, Lin Haoran. Microsatellite analysis of the genetic relationships between wild and cultivated giant grouper in the South China Sea. Journal of Genetics. 2016 (95),369-376.
9. Huang Wen, Liu Qizhi, Xie Junfeng, Li Yu, Wang Weimin, Xiao Jun, Li Shuisheng, Zhang Haifa, Zhang Yong*, Liu Shaojun*, Lin Haoran. Characterization of Triploid Hybrid Groupers from Interspecies Hybridization (Epinephelus coioides ♀ × Epinephelus lanceolatus ♂). Aquaculture Research. 2016 (47), 2195–2204.
10. Huang Wen, Qin Qinbo, Yang Huirong, Li Shuisheng, Hu Chaoqun, Wang Yude, Zhang Yong*,? Liu Shaojun*, Lin Haoran. Formation of diploid and triploid hybrid groupers and their 5S gene analysis. BMC Genetics. 2016, 17(1):136.
11. Xu Wen, Liu Yuchen, Liu Yali, Liu Li, Zhan Yonghao, Zhuang Chengle, Lin Junhao, Chen Mingwei, Li Jianfa, Cai Zhiming*, Huang Weiren*, Zhang Yong*. Artificial Small RNA for SequenceSpecific Repression of Gene Expression through RNase IIIEndonuclease Dicer. Oncotarget. 2016; 34(7): 54549–54554.
12. Sun Ying, Huang Yu, Hu Guojun, Zhang Xinhui, Ruan Zhiqiang, Zhao Xiaomeng, Guo Chuanyu, Tang Zhujing, Li Xiaofeng, You Xinxin, Lin Haoran*, Zhang Yong*,Shi Qiong*. Comparative Transcriptomic Study of Muscle Provides New Insights into the Growth Superiority of a Novel Grouper Hybrid. PLOS ONE. 2016, 11(12):e**.
13. Liu Yun,?Tang Haipei,?Xie Rui,? Li Shuisheng, Liu Xiaochun,?Lin Haoran,?Zhang Yong*,?Christopher H. K. Cheng*. Genetic Evidence for Multifactorial Control of the Reproductive Axis in Zebrafish. Endocrinology. 2017, 158(3):604–611.
14. Wang Qing, Liu Yun, Peng Cheng, Wang Xiang, Xiao Ling, Wang Dengdong, Chen Jiaxing, Zhang Haifa, Zhao Huihong, Li Shuisheng, Zhang Yong*, Lin Haoran. Molecular?and?cellular?investigation?of?sex?change?induced?by MT-feeding and MT-feeding?withdrawal?in?the?protogynous?orange-spotted?grouper, Epinephelus coioides. Biology of Reproduction, 2017, 97(2), 324–333.
15. Zheng Binbin, Li Shuisheng, Liu Yun, Li Yu, Chen Huapu, Tang Haipei, Liu Xiaochun, Lin Haoran, Zhang Yong*, Christopher H.K. Cheng*. Spexin Suppress Food Intake in Zebrafish: Evidence from Gene Knockout Study. Scientific Reports. 2017, 7: 14643
16. Ding Xu, Liang Yaosi, Peng Wan, Li Ruozhu, Lin Haoran, Zhang Yong*, Lu Danqi*. Intracellular TLR22 acts as an inflammation equalizer via suppression of NF-κB and selective activation of MAPK pathway in fish. Fish and Shellfish Immunology. 2018 (72), 646–657.
17. Liu Yali, Li Shuisheng*, Wang Qing, Chen Yu, Qi Xin，Liu Yun, Liu Xiaochun, Lin Haoran Zhang Yong*. Molecular identification of the Dyn/Kor system and its potential role in the reproductive axis of goldfish. General and Comparative Endocrinology. 2018, 257: 29–37.
18. Li Shuisheng, Liu Qiongyu, Xiao Ling, Tao Min, Shu Hu, Zhang Haifa, Lin Haoran, Zhang Yong*. Comparison of Gonadal Development in Diploid and Triploid Hybrid Groupers, Epinephelus coioides♀ × Epinephelus lanceolatus♂. Journal of the World Aquaculture Society. 2018, 49(2): 328–337.
19. Peng Cheng, Xiao Ling, Chen Huimin, Han Yulong，Huang Minwei, Zhao Mi, Li Shuisheng*, Liu Yun, Yang Yuqing, Zhang Haifa, Zhang Yong*, Lin Haoran. Cloning, expression and functional characterization of a novel luteinizing hormone receptor in the orange-spotted?grouper, Epinephelus coioides. General and Comparative Endocrinology. 2018, 267: 90–97.
20. Wang Qing, Huang Minwei, Peng Cheng, Wang Xiang, Xiao Ling, Wang Dengdong, Chen Jiaxing, Zhao Huihong, Zhang Haifa, Li Shuisheng, Yang Huirong*, Liu Yun*, Lin Haoran, Zhang Yong*. MT-feeding-induced impermanent sex reversal in the orange-spotted grouper during sex differentiation. International Journal of Molecular Sciences. 2018 (19), 2828.
21. Wang Mei, Deng Siping, Chen Huapu, Jiang Dongneng, Tian ChangXu, Yang Wei, Wu Tianli, Zhu Chunhua, Zhang Yong*, Li Guangli*. Phoenixin participated in regulation of food intake and growth in spotted scat, Scatophagus argus. Comparative Biochemistry and Physiology, Part B 2018(226): 36–44.
22. He Liangge, Liang Yaosi, Yu Xue, Peng Wan, He Jianan, Fu Lijun, Lin Haoran, Zhang Yong*, Lu Danqi*. Vibrio parahaemolyticus flagellin induces cytokines expression via toll-like receptor 5 pathway in orange-spotted grouper, Epinephelus coioides. Fish and Shellfish Immunology. 2019 (87), 573–581.
23. Han Chong, Li Qiang, Chen Qinghua, Zhou Guofeng, Huang Jianrong?, Zhang Yong*. Transcriptome analysis of the spleen provides insight into the immunoregulation of Mastacembelus armatus under Aeromonas veronii infection. Fish and Shellfish Immunology. 2019 (88), 272–283.
24. Han Chong, Li Qiang, Liu Jinmei, Hao Zhiqiang, Huang Jianrong?, Zhang Yong*. Characterization, evolution, and expression analysis of TLR7 gene subfamily members in Mastacembelus armatus (Synbranchiformes: Mastacembelidae). Developmental and Comparative Immunology. 2019 (95), 77–88.
25. Huang Minwei, Wang Qing, Chen Jiaxing, Chen Huimin, Xiao Ling, Zhao Mi, Zhang Haifa, Li Shuisheng, Liu Yun, Zhang Yong*, Lin Haoran. The co-administration of estradiol/17α-methyltestosterone leads to male fate in the protogynous orange-spotted grouper,?Epinephelus coioides. Biology of Reproduction, 2019, 100(3), 745–756.
26. Chen jiaxing, Xiao Ling , Peng Cheng, Ye Zhifeng, Wang Dengdong, Yang Yuqing, Zhang Haifa, Zhao Mi, Li Shuisheng, Zhang Yong*, Lin Haoran. Socially controlled male-to-female sex reversal in the protogynous orange-spotted grouper, Epinephelus coioides. Journal?of?Fish?Biology. 2019; 94:414–421.
27. Han Yulong, Zhao Mi*, Wang Le, Yu Zeshu, Wang Jing, Yu Qi, Xiao Ling, Lu Mingwei,?Zhang Yong*, Lin Haoran. Overexpression of anti-müllerian hormone gene?in vivo affects gonad sex differentiation in undifferentiated orange-spotted groupers (Epinephelus coioides). Frontiers in Endocrinology. 2019 Apr 5; 10:210.
28. Huang Minwei,?Chen Jiaxing, Liu ?Yun, Chen Huimin, Yu?Zeshu, Ye Zhifeng,?Peng Cheng, Xiao Ling, Zhao Mi, Li Shuisheng*, Lin Haoran, Zhang Yong*. New insights into the role of follicle-stimulating hormone in sex differentiation of the protogynous orange-spotted grouper, Epinephelus coioides. Frontiers in Endocrinology. 2019 May 15; 10:304.
29. Xiao Ling, Wang Dengdong, Guo Yin, Tang Zhujing, Liu Qiongyu, Li Shuisheng*, Zhang Yong*, Lin Haoran. Comparative transcriptome analysis of diploid and triploid hybrid groupers (Epinephelus coioides♀ × E.lanceolatus♂) reveals the mechanism of abnormal gonadal development in triploid hybrids. Genomics. 2019, 111(3):251-259.
30. Liu Yali, Wang Qing, Wang Xiang, Meng Zining, Liu Yun, Li Shuisheng*, Zhang Yong*, Lin Haoran. NKB/NK3 system negatively regulates the reproductive axis in sexually immature goldfish (Carassius auratus). General and Comparative Endocrinology. 2019, 281: 126–136.
31. Tang Lin, Chen Jiaxing, Ye Zhifeng, Zhao Mi, Meng Zining, Lin Haoran, Li Shuisheng*, Zhang Yong*. Transcriptomic Analysis Revealed the Regulatory Mechanisms of Oocyte Maturation and Hydration in Orange-Spotted Grouper (Epinephelus coioides). Marine Biotechnology. 2019, 19(1):11-21
32. Wang Dengdong, Chen Xiyang, Zhang Xinhui, Li Jia, Yi Yunhai, Bian Chao, Shi Qiong, Lin haoran, Li Shuisheng*, Zhang Yong*, You Xinxin*. Whole Genome Sequencing of the Giant Grouper (Epinephelus lanceolatus) and High-Throughput Screening of Putative Antimicrobial Peptide Genes. Marine Drugs.?2019,?17(9), 503.
33. Lyu Qingji, Hu Juan, Yang Xiankuan, Liu Xiaochun, Chen Yibin, Xiao Ling, Liu Yali, Wang Qing, Chen Jiaxing, Huang Minwei, Yu Zeshu, Yang Huirong, Shi Herong, Zhang Yong*, Zhao Huihong*. Expression profiles of dmrts and foxls during gonadal development and sex reversal induced by 17α-methyltestosterone in the orange-spotted grouper. General and Comparative Endocrinology. 2019, 274: 26–36.
34. Zhang Kewei, Wu TianLi, Chen Huapu, Jiang Dongneng, Zhu Chunhua, Deng Siping, Zhang Yong*, Li Guangli*. Estradiol-17β regulates the expression of insulin-like growth factors 1 and 2 via estradiol receptors in spotted scat (Scatophagus argus). Comparative Biochemistry and Physiology, Part B 2019(237): 110328.
35. Wang Xiang, Jiang Shoujia, Zheng Leyun, Xiao Ling, Zhang Xinhui, Wang Dengdong, Li Shuisheng, Shi Qiong, Wu Shuiqing, Lin Haoran, You Xinxin*, Zhang Yong*. An SNP-based genetic map and QTL mapping for growth traits in the red-spotted grouper Epinephelus akaara.?Genes. 2019,?6, 793.
36. Chen jiaxing, Chen Huapu, Peng Cheng, Ye Zhifeng, Zhao Mi, Xiao Ling, Zhang Haifa, Li Shuisheng*, Lin Haoran, Zhang Yong*. A highly efficient method of inducing sex change using social control in the protogynous orange-spotted grouper (Epinephelus coioides). Aquaculture. 2020; 517:734787.
37. Tang Ling, Xiao Xinxun, Shi Herong, Chen Jiaxing, Han Chong, Huang Hai, Lin Haoran, Zhang Yong*, Li Shuisheng*. Induction of oocyte maturation and changes in the biochemical composition, physiology and molecular biology of oocytes during maturation and hydration in the orange-spotted grouper (Epinephelus coioides). Aquaculture. 2020; 522:735115.
38. Han Chong, Zhu Qiaoying, Lu Haoming, Wang Chongwei, Zhou Xingni, Peng Cheng, Tang Lin, Han Linqiang, Chen Jiehu, Li Shuisheng, Li Guifeng, Lin Haoran, Zhang Yong*, Li Shuisheng*. Screening and characterization of sex-specific markers developed by a simple NGS method in mandarin fish (Siniperca chuatsi). Aquaculture. 2020; 527:735495.
39. Yu Qi, Peng Cheng, Ye Zhifeng, Tang Zhujing, Li Shuisheng, Xiao Ling, Liu Su, Yang Yuqing, Zhao Mi*, Zhang Yong*, Lin Haoran. An estradiol-17β/miRNA-26a/cyp19a1a?regulatory feedback loop in the protogynous hermaphroditic fish,?Epinephelus coioides. Molecular and Cellular Endocrinology. 2020, 504: 110689.
40. Qiao Xifeng, Li Pingchao, He Jianan, Yu Zeshu, Chen Jiaxing, He Liangge, Yu Xue, Lin Haoran, Lu Danqi*, Zhang Yong*. Type F scavenger receptor expressed by endothelial cells (SREC)-II from Epinephelus coioides is a potential pathogen recognition receptor in the immune response to Vibrio parahaemolyticus infection. Fish and Shellfish Immunology. 2020 (98), 262–270.
41. Yu Xue, Li Ruozhu,He Liangge, Ding Xu, Liang Yaosi, Peng Wan, Shi Herong, Lin Haoran, Zhang Yong*, Lu Danqi*. MicroRNA-29b modulates the innate immune response by suppressing IFNγs production in orange-spotted grouper (Epinephelus coioides). Fish and Shellfish Immunology. 2020(104), 537–544.
42. Chen jiaxing, Peng Cheng, Yu Zeshu, Xiao Ling, Yu Qi, Li Shuisheng*, Zhang Haifa, Lin Haoran, Zhang Yong*. The administration of cortisol induces female-to-male sex change in the protogynous orange-spotted grouper, Epinephelus coioides. Frontiers in Endocrinology. 2020 Apr 5; 10:210.
43. Xiao Ling, Gui Yin, Wang Dengdong, Zhao Mi, Hou Xin, Li Shuisheng*, Lin Haoran, Zhang Yong*. Beta-Hydroxysteroid Dehydrogenase Genes in Orange-spotted Grouper (Epinephelus coioides): Genome-wide Identification and Expression Analysis During Sex Reversal. Frontiers in Genetics. 2020 May 4; 11:161.
44. Peng Cheng, Wang Qing, Chen Jiaxing, Han Yulong，Zhang Wenrui, Wang Dengdong, Li Shuisheng, Tao Min, Shi Herong, Lin Haoran, Zhao Huihong*, Zhang Yong*. Retinoic acid and androgen influence germ cells development and meiotic initiation in juvenile orange-spotted grouper, Epinephelus coioides. General and Comparative Endocrinology. 2020, 281: 126–136.
45. Peng Cheng, Wang Qing, Shi Herong, Chen Jiaxing, Li Shuisheng, Zhao Huihong*, Lin Haoran, Yang Jianchun*, Zhang Yong*. Natural sex change in mature protogynous orange-spotted grouper (Epinephelus coioides): gonadal restructuring, sex hormone shifts and gene profiles. Journal?of?Fish?Biology. 2020.