简单介绍
邹滔滔，博士，中山大学教授，博士生导师。中山大学“****”中青年杰出人才。2010年毕业于武汉大学化学学院（导师：杨楚罗教授），2015年2月毕业于香港大学化学系（导师：支志明院士），其后三年时间，分别在斯科利普斯研究所（导师：Xiang-Lei Yang教授、Paul Schimmel教授)、香港大学（导师：支志明教授）、华威大学（导师Peter J Sadler教授）从事博士后研究工作，研究方向为药物化学生物学和生物无机化学，长期致力于含金属抗癌药物的开发，近期研究方向集中在设计新型抗癌前体药物和发展具有抗癌免疫活性的小分子药物等领域。以第一作者或通讯（含共同）在Nature Commun, Angew Chem Int Ed, Chem Soc Rev, Chem Sci, Adv Mater, Chem Commun等期刊发表多篇论文。
scan for English version
ORCID:?https://orcid.org/0000-0001-9129-4398

Researcher ID: G-2044-2018?
Group website:?ttzouchem.wixsite.com/zoulab

?
招生招聘信息课题组长期招聘具有化学生物学、药物化学背景，对无机药物感兴趣的博士后。
课题组2021年尚有学硕和专硕士各1名，欢迎联系。
?
所获荣誉
2020年? AsBIC Graeme Hanson Early Career Award
2019年 “珠江人才计划”引进青年拔尖人才
2019年 ?深圳市自然科学一等奖（排名第五）
2016年? CAS/SciFinder Future Leaders
2015年??Reaxys PhD Prize (Finalist)
2015年??Springer Theses Prize
2015年??Li Ka Shing Prize
2014年??Hong Kong Young Scientist Award（winner）?
?

代表性论文
Long, Y.?; Cao, B.?; Xiong, X.; Chan, A. S. C.; Sun, R. W.-Y.; Zou, T.*, Bioorthogonal Activation of Dual Catalytic and Anti-Cancer Activities of Organogold(I) Complexes in Living Systems. Angew. Chem. Int. Ed. 2021, 60, 4133-4141. (Hot Paper)
Luo, H.; Cao, B.; Chan, A. S. C.; Sun, R. W.-Y.; Zou, T.*, Cyclometalated Gold(III)-Hydride Complexes Exhibit Visible Light-Induced Thiol Reactivity and Act as Potent Photo-Activated Anti-Cancer Agents. Angew. Chem. Int. Ed. 2020, 59, 11046-11052. (Hot Paper, highlighted as?inside back cover)
Huang, K.-B.?; Wang, F.-Y.?; Feng, H.-W.; Luo, H.; Long, Y.; Zou, T.*; Chan, A. S. C.; Liu, R.; Zou, H.; Chen, Z.*; Liu, Y.-C.; Liu, Y.-N.; Liang, H.*, An Aminophosphonate Ester Ligand-Containing Platinum(II) Complex Induces Potent Immunogenic Cell Death In Vitro and Elicits Effective Anti-Tumour Immune Responses In Vivo. Chem. Commun. 2019. 55, 13066-13069. (Inside front cover)
Zou, T.;? Lok, C.-N.,? Wan, P.-K., Zhang, Z.-F., Fung, S.-K., Che, C.-M.* Anticancer Metal N-Heterocyclic carbene complexes of gold, platinum and palladium, Curr. Opin. Chem. Bio., 2018, 43, 30-36.
Fung, S. K.;? Zou, T.;? Cao, B.; Lee, P.-Y.; Fung, Y. M. E.; Hu, D.; Lok, C.-N.; Che, C.-M.*, Cyclometallated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets, Angew. Chem. Int. Ed. 2017, 56, 3892-3896. (Very Important Paper).
Fung, S. K.;? Zou, T.;? Cao, B.; Chen, T.; To, W.-P.; Yang, C.; Lok, C.-N.; Che, C.-M.*, Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA, Nat. Commun. 2016, 7, 10655.
Zou, T.; Lum, C. T.; Lok, C.-N.; Zhang, J.-J.; Che, C.-M.*, Chemical biology of anticancer gold(III) and gold(I) complexes. Chem. Soc. Rev. 2015, 44, 8786-8801 (Outside Front Cover).
Tsai, J. L.-L.;? Zou, T.;? Liu, J.; Chen, T.; Chan, A. O.-Y.; Yang, C.; Lok, C.-N.; Che, C.-M.*, Luminescent platinum(ii) complexes with self-assembly and anti-cancer properties: hydrogel, pH dependent emission color and sustained-release properties under physiological conditions. Chem. Sci. 2015, 6, 3823-3830.
Zou, T.; Lum, C. T.; Lok, C.-N.; To, W.-P.; Low, K.-H.; Che, C.-M.*, A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo. Angew. Chem. Int. Ed. 2014, 53, 5810-5814.
Zou, T.;? Liu, J.;?Lum, C. T.; Ma, C.; Chan, R. C.-T.; Lok, C.-N.; Kwok, W.-M.; Che, C.-M.*, Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double Stranded DNA and RNA: Differential Emissions and Anticancer Activities. Angew. Chem. Int. Ed. 2014, 53, 10119-10123.
Lok, C.-N.;? Zou, T.;? Zhang, J.-J.; Lin, I. W.-S.; Che, C.-M.*, Controlled-Release Systems for Metal-Based Nanomedicine: Encapsulated/Self-Assembled Nanoparticles of Anticancer Gold(III)/Platinum(II) Complexes and Antimicrobial Silver Nanoparticles. Adv. Mater. 2014, 26, 5550-5557.
Zou, T.; Lum, C. T.; Chui, S. S.-Y.; Che, C.-M.*, Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol “Switch-on” Fluorescent Probes and Anti-Cancer Agents. Angew. Chem. Int. Ed. 2013, 52, 2930-2933 (Very Important Paper)
(? equal contribution, * Corresponding author)
?
书籍（章节）
Zou, T., Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II): Thiol "Switch-on" Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents; Springer Theses, Springer, 2016,?ISBN 978-981-10-0657-9.
Zou, T., Hung, F.-F., Yang, C., Che, C.-M.* Strongly Phosphorescent Transition-Metal Complexes with N-Heterocyclic Carbene Ligands as Cellular Probes. In: Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents Vol. 165 (Ed.: Lo, K. K.-W.). Springer Berlin Heidelberg, 2015, pp. 181-203.
?
专利
?邹滔滔，罗和江，陈新滋，一种光响应的环金属金(III)氢化物及其制备方法和应用。中国发明专利申请，专利号0.1.
Chi Ming Che, Taotao Zou, Novel gold(III) complexes containing N-heterocyclic carbene ligand, synthesis, and applications in cancer treatment and thiol detection. PCT Int. Appl. US 14/078,742, US** B2 (granted), EP**A1, EP**A4, US, WOA1.
?Chi Ming Che, Taotao Zou, A method of using binuclear gold(I) compounds for cancer treatment. PCT Int. Appl. US 14/070,096, US** B2 (granted), CNA, EP**A1, EP**A4, US, WOA1.
Chi Ming Che, Sin Ki Fung, Taotao Zou, A method of using d⁸ square planar metal complexes to target mismatched DNA. PCT Int. Appl. US 2-A1?.?