翁江，男，1982年11月生，博士，副教授，博士生导师。主要研究领域为药物合成化学和有机合成化学。先后承担国家自然科学基金、广东省自然科学基金重等多项基金项目，在国内外重要学术期刊上发表高水平论文50余篇，申请和获得授权发明专利4项。
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联系方式
办公电话：
E-mail: wengj2@mail.sysu.edu.cn
研究方向不对称催化和手性技术
手性药物的高效合成
活性天然产物的全合成
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学习和工作经历
2012/7-至今，中山大学药学院，历任讲师和副教授
2017/12-2018/12，美国Scripps研究所，访问****
2010/07 – 2012/07，中山大学药学院，博士后
2007/09 – 2010/06，中山大学药学院，有机化学专业，博士
2005/09 – 2007/06，中山大学化工学院，有机化学专业，硕士
2001/09 – 2005/06，湖北大学化材学院，应用化学专业，学士
教学情况有机化学；有机化学实验
科研项目近年主持的纵向科研项目：
1. 国家自然科学基金-青年科学基金项目：环戊烯酮类前列腺素的合成新方法及其靶向白血病干细胞活性研究；**；2016.1-2018.12；
2. 广东省自然科学基金项目-自由申请项目：基于有机催化串联反应构建环状DPP-4抑制剂及其降血糖活性研究；2015A；2015.8.1-2018.8.1；
3. 广东省自然科学基金项目-博士启动项目：有机催化串联Michael/Wittig/Aldol反应及其在前列腺素合成中的应用；S20**；2013.10-2015.10；
4. 广东省医学科学基金项目：前列腺素F的高效合成新方法研究；A**；2015.7-2017.6；
5. 中央高校基本科研业务费-中山大学青年教师培育计划项目：2012.11-2015.11；
6. 中山大学青年教师起步资助计划；2012.12-2013.12
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论著专利发表论文：
1. Tao Zhong, Zhi-Da Chen, Ji-Tao Yi,?Gui Lu,*? Jiang Weng.* Recent progress in the synthesis of sulfonyl fluorides for SuFEx click chemistry. Chin. Chem. Lett. 2021, DOI: 10.1016/j.cclet.2021.03.035.
2.?Tao Zhong, Meng-Ke Pang,?Zhi-Da Chen, Bin Zhang, Jiang Weng,*?Gui Lu. Copper-free Sandmeyer-type Reaction for the Synthesis of Sulfonyl Fluorides. Org. Lett. 2020, 22, 3072-3078.
3.?Wen-Run Zhu,?Qiong Su, Hong-Juan Diao, Er-Xuan Wang,?Feng Wu, Yun-Long Zhao, Jiang Weng,*?Gui Lu.*? Enantioselective Dehydrative gamma-Arylation of alpha-Indolyl Propargylic Alcohols with Phenols: Access to Chiral Tetrasubstituted Allenes and Naphthopyrans. Org. Lett. 2020, 22, 6873-6878.?
4. Wen-Run Zhu,?Kai Liu, Jiang Weng,*?Wei-Hua Huang,?Wei-Jie Huang, Qing Chen,?Ning Lin,*?Gui Lu.*?Catalytic Asymmetric Synthesis of Vicinal Tetrasubstituted Diamines via Umpolung Cross-Mannich Reaction of Cyclic Ketimines.?Org. Lett. 2020, 22, 5014-5019
5. Jing Guo, Ying Xie,? Wen-Tian Zeng, Qiao-Lei Wu, Jiang Weng,*?Gui Lu.*? Visible-Light Catalyzed [1+2+2] Cycloaddition Reactions Enabled by the Formation of Methylene Nitrones. Adv. Synth. Catal. 2020, 362: 5450-5456.
6. Wei-Hua Huang,?Gong-Bin Huang, Wen-Run Zhu, Jiang Weng,*?Gui Lu.*?Transition Metal-free Synthesis of α-Aryl Ketones via Oxyallyl Cation Capture with Arylboronic Acids.?Org. Chem. Front.?2020,?7,?2480-2485.
7.??Hang Shi, Yi Lu,?Jiang Weng,?Katherine L. Bay, Xiangyang Chen, Keita Tanaka, Pritha Verma, Kendall N. Houk,* Jin-Quan Yu.* Differentiation and functionalization of remote C-?H bonds in adjacent positions. ?Nature Chem. 2020,?12,?399-404.
8. Yan-Shi Xiong, Bin Zhang,?Yang Yu, Jiang Weng,*?Gui Lu.*?Construction of sulfonyl phthalides via copper-catalyzed oxysulfonylation of 2-vinylbenzoic acids with sodium sulfinates. J. Org. Chem. 2019, 84, 13465-13472.
9. Guoqin Xia,?Jiang Weng,?Luoyan Liu,Pritha?Verma, Ziqi?Li, Jin-Quan Yu.* Reversing conventional site-?selectivity in C(sp3)?-?H bond activation. Nature Chem. 2019,?11,?571-577.
10.Jing Guo, Gong-Bin Huang, Qiao-Lei Wu,?Ying Xie,?Jiang Weng,*?Gui Lu.*?An efficient approach to access 1,1,2-triarylethanes enabled by the organo-photoredox-catalyzed decarboxylative addition reaction. Org. Chem. Front. 2019, 6, 1955-1960.
11.?Gong-Bin Huang, Wei-Hua Huang,?Jing Guo, Xu Dong-Liang, Xiao-Chen Qu, Pei-Hong Zhai, Xiu-Hua Zheng, Jiang Weng,*?Gui Lu.*?Enantioselective synthesis of? triarylmethanes via organocatalytic 1,6-addition of arylboronic acids to para-quinone methides. Adv. Synth.?Catal. 2019, 361, 1241-1246.
12. Yan-Shi Xiong, Jiang Weng,*?Gui Lu.*?Manganese(III)-mediated and -catalyzed decarboxylative hydroxysulfonylation of arylpropiolic acids with sodium sulfinates in water. Adv. Synth. Catal. 2018, 360, 1611-1616.
13. Jing Guo, Qiao-Lei Wu, Ying Xie, Jiang Weng,*?Gui Lu.*?Visible-light-mediated decarboxylative benzylation of imines with arylacetic acids. J. Org. Chem. 2018, 83, 12559-12567.
14.?Yan-Shi Xiong,?Yang Yu, Jiang Weng,*?Gui Lu.*?Copper-?catalyzed peri-?selective direct sulfenylation of 1-?naphthylamines with disulfides. Org. Chem. Front.?2018,?5,?982-989.
15. Jun-Ming Li,?Yong-Heng Wang,?Yang Yu,?Ruibo Wu,?Jiang Weng,*?Gui Lu.*?Copper-catalyzed remote C–H functionalizations of naphthylamides through coordinating activation strategy and single-electron-transfer (SET) mechanism.?ACS Catalysis,?2017,?7, 2661-2667.
16. Jing Guo, Zi-Hui Lin, Kai-Bin Chen, Ying Xie; Albert S. C.Chan, Jiang Weng,*?Gui Lu.*?Asymmetric amination of 2-substituted indolin-3-ones catalyzed by natural cinchona alkaloids. Org. Chem. Front. 2017, 4, 1400-1406.
17.?Wei-Jie Huang, Qing Chen, Ning Lin*, Xian-Wen Long, Wei-Gao Pan, Yan-Shi Xiong,?Jiang Weng*, Gui Lu* Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions.?Org. Chem. Front.,?2017,?4, 472-482.
18.?Can Liu,?Jiang Weng*, Zi-Hui Lin, Wei-Jie Huang, Jing Guo, Lin-Jie Huang, Gui Lu*, Asymmetric synthesis of vicinal amino alcohols via organocatalytic sequential α-amination/Grignard addition reactions of aldehydes.?Tetrahedron: Asymmetry,?2017,?28, 41-46.
19. Ji-Quan Zhang, Yong-Jie Luo, Yan-Shi Xiong, Yang Yu, Zheng-Chao Tu, Zi-Jie Long, Xiao-Ju Lai, Hui-Xuan Chen, Yu Luo,?Jiang Weng, Gui Lu. Design, Synthesis, and Biological Evaluation of Substituted Pyrimidines as Potential Phosphatidylinositol 3-Kinase (PI3K) Inhibitors.?J. Med. Chem.?2016, 59, 7268–7274.?
20. Jun-Ming Li,?Jiang Weng,* Gui Lu, Albert S.C. Chan. Copper-catalyzed C5-regioselective C-H sulfonylation of 8-aminoquinoline amides with aryl sulfonyl chlorides.?Tetrahedron Lett.,?2016,?57, 2121-2124.?
21.?Jing Guo,?Jiang?Weng,* Gong-Bin?Huang,??Lin-Jie?Huang, Albert S. C.?Chan,??Gui Lu.*?Indoxyl-based umpolung strategy for the synthesis of unsymmetrical 3,3'-biindoles.?Tetrahedron Lett.,?2016,?57,?5493-5496.?
22.?Jiang Weng,* Sheng Wang, Lin-Jie Huang , Zhang-Yi Luo, Gui Lu.* ?Stereoselective Synthesis of Epoxyisoprostanes: An Organocatalytic and "Pot-economy" Approach.?Chem. Commun.?2015,?51, 10170-10173.?(Highlighted?by?Organic?Chemistry?Portal)
23.?Lin-Jie Huang,?Jiang Weng,*?Sheng Wang, Gui Lu.*?Organocatalytic Diels-Alder Reaction of 2-Vinylindoles with Methyleneindolinones: An Efficient Approach to Functionalized Carbazolespirooxindoles.?Adv. Synth. Catal.?2015,?357(5), 993-1003.??(Highlighted?by?X-MOL)
24.?Jiang Weng, Jun-Ming Li, Feng-Quan Li, Zhi-Sheng Xie, Gui Lu.*?Asymmetric domino nitro-Michael/Horner-Wadsworth-Emmons reaction for disubstituted cyclohexenecarboxylate annulation: efficient synthesis of DPP-4 inhibitor ABT-341 and influenza neuraminidase inhibitors.?Adv. Synth. Catal.,?2012,?354, 1961-1970.
25.?Jiang Weng, Yong-Bo Li, Rui-Bin Wang, Gui Lu.?Organocatalytic Michael reaction of nitroenamines with aldehydes: efficient asymmetric synthesis of (?)-oseltamivir.?ChemCatChem,?2012,?4, 1007-1012. (Invited paper)
26.?Jiang Weng,?Yong-Bo Li, Rui-Bin Wang, Feng-Quan Li, Can Liu, Albert S. C. Chan, Gui Lu.?A practical and azide-free synthetic approach to oseltamivir from diethyl D-tartrate.?J. Org. Chem.,?2010,?75, 3125-3128. (Highlighted by?SYNFACTS, 2010,?8, 857)?
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发明专利：
■??授权专利：
1. Process for the preparation of 1-nitro-4-oxobutanylamides. European Patent application, EP **.9. Juraj Rehak, Gui Lu, Julius Durmis,?Jiang Weng, Henrich Brath, Yong-Bo Li, Martin Hutka, Stefan Toma, Attila Latika.?（欧洲发明专利）
2.?一种具有流感病毒神经胺酸酶抑制活性的环己烯衍生物的制备，中国发明专利。?7.X.?发明人：鲁桂、黎逢权、翁江、李勇波
3.??一种3，3’-双?吲哚化合物的制备方法，中国发明专利。申请号：5.9?发明人：翁江、鲁桂、郭靖
■??申请专利：
1.??一种醋酸阿比特龙酯的制备方法，中国发明专利。申请号：8.X.?发明人：翁江、鲁桂、黄琳杰、王尧