重要学术研究成果与贡献：

学术论著与教材：

代表性论文

1.ErshengKuang,CherylY.M.Okumura,SharonSheffy-Levin,TalVarsano,VincentChih-WenShu,JianfeiQi,IngridR.Niesman,Huei-JiunYang,CarlosLópez-Otín,WeiYuanYang,JohnC.Reed,LimorBroday,VictorNizet,&Ze’evA.Ronai.RegulationofATG4BstabilitybyRNF5limitsbasallevelsofautophagyandinfluencessusceptibilitytobacterialInfection.PlosGenetics.2012,Accepted.

2.KuangE,FuB,LiangQ,MyoungJ,ZhuF.Phosphorylationofeukaryotictranslationinitiationfactor4B(EIF4B)byopenreadingframe45/p90ribosomalS6kinase(ORF45/RSK)signalingaxisfacilitatesproteintranslationduringKaposisarcoma-associatedherpesvirus(KSHV)lyticreplication.J.BiolChem.2011;286:41171-41182.

3.KuangE,WuF,ZhuF.MechanismofsustainedactivationofribosomalS6kinase(RSK)andERKbykaposisarcoma-associatedherpesvirusORF45:multiproteincomplexesretainactivephosphorylatedERKandRSKandprotectthemfromdephosphorylation.JBiolChem.2009;284(20):13958-68.

4.KuangE,TangQ,MaulGG,ZhuF.Activationofp90ribosomalS6kinase(RSK)byORF45ofKaposi'ssarcomaassociatedherpesvirusanditsroleinvirallyticreplication.JVirol.2008;82(4):1838-50.

5.WanQ*,KuangE*,DongW,ZhouS,XuH,QiY,LiuY.Reticulon3mediatesBcl-2accumulationinmitochondriainresponsetoendoplasmicreticulumstress.Apoptosis.2007;12(2):319-28.(*Co-firstauthor)

6.KuangE,WanQ,LiX,XuH,ZouT,QiY.ERstresstriggersapoptosisinducedbyNogo-B/ASYoverexpression.ExpCellRes.2006;312(11):1983-8.

7.LiX*,KuangE*,DaiW,ZhouB,YangF.EfficientinhibitionofhepatitisBvirusreplicationbyhammerheadribozymesdeliveredbyhepatitisdeltavirus.VirusRes.2005;114(1-2):126-32.(*Co-firstauthor)

8.KuangE,WanQ,LiX,XuH,LiuQ,QiY.ERCa2+depletiontriggersapoptoticsignalsforendoplasmicreticulum(ER)overloadresponseinducedbyoverexpressedreticulon3(RTN3/HAP).JCellPhysiol.2005;204(2):549-59.

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