招生信息
教育背景
工作经历
专利与奖励
出版信息
科研活动
指导学生
基本信息
吴垠女博导中国科学院深圳先进技术研究院
电子邮件： yin.wu@siat.ac.cn
通信地址： 中国科学院深圳先进技术研究院
邮政编码： 518055
研究领域
医学成像与信号处理
磁共振成像
招生信息
招生专业
081104-模式识别与智能系统083100-生物医学工程081002-信号与信息处理招生方向
医学成像与信号处理教育背景
2004-09--2008-11香港大学博士2002-09--2004-07哈尔滨工业大学硕士1998-09--2002-07哈尔滨工业大学学士工作经历
2017-12~今，中国科学院深圳先进技术研究院, 研究员
2014-08~2015-08，哈佛医学院/麻省总医院,Research Fellow
2010-02~2017-11，中国科学院深圳先进技术研究院,副研究员
2009-02~2010-01，中国科学院深圳先进技术研究院,助理研究员
专利与奖励
奖励信息
（1） Distinguished Reviewer of Journal of Magnetic Resonance Imaging, 其他, 2018（2） Distinguished Reviewer of Journal of Magnetic Resonance Imaging, 其他, 2016（3） Distinguished Reviewer of Magnetic Resonance in Medicine, , 其他, 2015（4） ISMRM E. K. Zavoisky Stipend, , 其他, 2014（5） SCMR Regional Scholarship, , 其他, 2013（6） ISMRM E. K. Zavoisky Stipend, , 其他, 2012（7） ISMRM E. K. Zavoisky Stipend, , 其他, 2011（8） ISMRM Educational Stipend, , 其他, 2008（9） ISMRM Educational Stipend, , 其他, 2007（10） ISMRM Educational Stipend, , 其他, 2006专利成果
（ 1 ） 磁共振弥散张量成像方法和系统, 发明, 2012, 第 1 作者, 专利号: ZL 6.1（ 2 ） 横向弛豫时间测量方法及系统, 发明, 2013, 第 5 作者, 专利号: ZL 4.X（ 3 ） 磁共振动态成像方法, 发明, 2012, 第 5 作者, 专利号: ZL 9.5（ 4 ） 磁共振弥散张量成像方法及系统, 发明, 2015, 第 2 作者, 专利号: ZL 4.8（ 5 ） 测量肿瘤组织吸入卡波金气体后氧浓度的方法及系统, 发明, 2012, 第 5 作者, 专利号: ZL 9.0（ 6 ） 弥散加权成像方法及系统, 发明, 2012, 第 5 作者, 专利号: ZL 13（ 7 ） 弥散张量成像方法及系统, 发明, 2012, 第 1 作者, 专利号: ZL 8.3（ 8 ） 弥散张量成像方法及系统, 发明, 2014, 第 1 作者, 专利号: ZL 8.0（ 9 ） 心脏磁共振实时电影成像的数据处理方法及系统, 发明, 2015, 第 1 作者, 专利号: ZL 5.5（ 10 ） 一种心脏磁共振实时电影成像方法及系统, 发明, 2016, 第 1 作者, 专利号: ZL 3.1（ 11 ） 磁共振成像采集系统和磁共振成像采集方法, 发明, 2015, 第 1 作者, 专利号: ZL 7.7（ 12 ） 一种实现快速弥散张量成像的方法, 发明, 2014, 第 1 作者, 专利号: ZL 6.6（ 13 ） 基于机器学习的并行磁共振成像GRAPPA方法, 发明, 2015, 第 3 作者, 专利号: 3.4（ 14 ） 磁共振系统的自适应有源自动匀场方法和系统, 发明, 2017, 第 2 作者, 专利号: ZL 3.X（ 15 ） 化学交换饱和转移效应定量方法、装置及电子设备, 发明, 2017, 第 1 作者, 专利号: CN2.6（ 16 ） pH定量方法, 发明, 2017, 第 1 作者, 专利号: PCT/CN2017/120104（ 17 ） 氨基质子转移效应的确定方法及装置, 发明, 2019, 第 1 作者, 专利号: ZL 8.5（ 18 ） 一种医学图像参数的拟合方法和装置, 发明, 2019, 第 1 作者, 专利号: ZL 6.4（ 19 ） 心脏实时电影成像图像处理方法和系统, 发明, 2015, 第 1 作者, 专利号: ZL 9.2（ 20 ） 大脑纵向弛豫值测量方法和装置, 发明, 2019, 第 2 作者, 专利号: ZL 4.3（ 21 ） 磁共振化学交换饱和转移成像方法和系统, 发明, 2019, 第 2 作者, 专利号: ZL 6.0（ 22 ） 多b值弥散张量成像采样方法, 发明, 2012, 第 2 作者, 专利号: ZL 1.2（ 23 ） 一种磁共振心脏血流速度的测量方法及装置, 发明, 2019, 第 3 作者, 专利号: ZL 2.3出版信息
发表论文
（1）Automated segmentation of the left ventricle from MR cine imaging based on deep learning architecture,Biomedical Physics & Engineering Express,2020,第1作者（2）Diagnostic performance of multiparametric MRI in the evaluation of treatment response in glioma patients at 3T,J Magn Reson Imaging,2020,通讯作者（3）Direct saturation corrected amide proton transfer tumor MRI at 3 Tesla,Magnetic Resonance in Medicine,2019,第1作者（4）Mapping tissue pH in an experimental model of acute stroke - Determination of graded regional tissue pH changes with non-invasive quantitative amide proton transfer MRI,Neuroimage,2019,第1作者（5）A Generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol,Magnetic Resonance in Medicine,2018,第1作者（6）pH-sensitive amide proton transfer (APT) effect dominates the magnetization transfer asymmetry contrast during acute ischemia — Quantification of multi-pool contribution to in vivo CEST MRI,Magnetic Resonance in Medicine,2018,第1作者（7）Assessment of chemoradiotherapy response in glioma with magnetic resonance amide proton transfer imaging in a rodent model,Proceedings of IEEE EMBC,2017,通讯作者（8）Direct diffusion tensor estimation using model-based method with spatial and parametric constraints,Medical Physics,2017,第3作者（9）Fast T1 mapping of the brain at high field using Look-Locker and fast imaging,Magnetic Resonance Imaging,2017,第4作者（10）Improved workflow for quantifying left ventricular function via cardiorespiratory-resolved analysis of free-breathing MR real-time cines,Journal of Magnetic Resonance Imaging,2017,第1作者（11）pH imaging reveals worsened tissue acidification in diffusion kurtosis lesion than the kurtosis/diffusion lesion mismatch in an animal model of acute stroke,J Cereb Blood Flow Metab,2017,第1作者（12）Comparison of image sensitivity between conventional tensor-based and fast diffusion kurtosis imaging protocols in a rodent model of acute ischemic stroke,NMR Biomed,2016,第1作者（13）A review of optimization and quantification techniques for chemical exchange saturation transfer MRI toward sensitive in vivo imaging,Contrast Media and Molecular Imaging ,2015,第1作者（14）Efficient method for analyzing MR real-time cines: toward accurate quantification of left ventricular function,Journal of Magnetic Resonance Imaging,2015,第1作者（15）Importance of saturation power optimization in improving the estimation accuracy of chemical exchange rates with the omega plot: a simulation study,2015 Proceedings of International Society of Magnetic Resonance in Medicine,2015,通讯作者（16）Investigation of the performance of variable-density Z-spectrum acquisition scheme in MR chemical exchange saturation transfer effect quantification,IEEE EMBC,2015,通讯作者（17）Accelerated MR diffusion tensor imaging using distributed compressed sensing,Magn Reson Med,2014,第1作者（18）An efficient algorithm for volumetric measurement of left ventricle using real time cines,2014 Proceedings of International Society of Magnetic Resonance in Medicine ,2014,第1作者（19）A robust and fast SSFP cine for the evaluation of LV function at 3T,2014 Proceedings of International Society of Magnetic Resonance in Medicine,2014,第1作者（20）Importance of high temporal resolution in peak flow velocity quantification by phase-contrast imaging,2014 Proceedings of International Society of Magnetic Resonance in Medicine,2014,第1作者（21）Effect of b-value in revealing postinfarct myocardial microstructural remodeling using MR diffusion tensor imaging,Magnetic Resonance Imaging,2013,第1作者（22）Investigation of muscle degeneration process in young rats with ischemia injury using MR diffusion tensor imaging,IEEE EMBC,2013,通讯作者（23）Preliminary MR DTI study of age-related regeneration process of skeletal muscle with ischemia injury,2013 Proceedings of International Society of Magnetic Resonance in Medicine,2013,通讯作者（24）An efficient approach for analysis of real-time cine for LV function quantification,2013 Proceedings of International Society of Magnetic Resonance in Medicine,2013,第1作者（25）Robust and fast SSFP for the evaluation of LV function at 3T,2013 SCMR Annual Sessions,2013,第1作者（26）Feasibility study of fast diffusion tensor imaging based on distributed compressed sensing.,19th ISMRM Annual Meeting Exhibition,2012,第1作者（27）Biexponential diffusion tensor analysis of myocardial structural alteration in rabbit models with myocardium infarction,19th ISMRM Annual Meeting Exhibition,2012,第1作者（28）Effect of b-value on DTI sensitivity in revealing myocardial structure degradation in rabbit models with acute myocardium infarction,19th ISMRM Annual Meeting Exhibition,2012,第1作者（29）Reduced transverse relaxation rate (RR2) for improved sensitivity in monitoring myocardial iron in thalassemia,Journal of Magnetic Resonance Imaging,2011,通讯作者（30）Statistical evaluation of fitting models of diffusion tensor imaging in characterizing normal porcine myocardium,The 4th International Conference on BioMedical Engineering and Informatics,2011,通讯作者（31）MR diffusion tensor investigation of transmural heterogeneity of myocardium structural remodeling in postinfarct porcine model,2011 Proceedings of International Society of Magnetic Resonance in Medicine,2011,第1作者（32）Impact of b-value on DTI indices of left ventricular porcine myocardium: a preliminary study,2011 Proceedings of International Society of Magnetic Resonance in Medicine,2011,第1作者（33）Transmural heterogeneity of left ventricular myocardium remodeling in postinfarct porcine model revealed by MR diffusion tensor imaging,Journal of Magnetic Resonance Imaging,2011,第1作者（34）C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease,Hypertension,2010,第4作者（35）MR study of the effect of infarct size and location on left ventricular functional and structural remodeling in porcine models,Journal of Magnetic Resonance Imaging,2009,第1作者（36）MR investigation of the coupling between myocardial fiber architecture and cardiac contraction,Conf Proc IEEE Eng Med Biol Soc.,2009,第1作者（37）MR study of postnatal development of myocardial structure and left ventricular function,Journal of Magnetic Resonance Imaging,2009,第1作者（38）Measurement of common carotid artery lumen dynamics during cardiac cycle using MR TrueFISP cine imaging,Journal of Magnetic Resonance Imaging,2008,第3作者（39）MR diffusion tensor imaging study of postinfarct myocardium structural remodeling in a porcine model,Magnetic Resonance in Medicine,2007,第2作者（40）Study of myocardial fiber pathway using magnetic resonance diffusion tensor imaging,Magnetic Resonance Imaging,2007,第2作者（41）In vivo MR coronary artery imaging in mice,Conf Proc IEEE Eng Med Biol Soc.,2007,第1作者（42）Diffusion tensor MRI study of myocardium remodeling after infarction in porcine model,Conf Proc IEEE Eng Med Biol Soc.,2006,第1作者（43）Myocardial fiber length mapping with MR diffusion tensor imaging,Conf Proc IEEE Eng Med Biol Soc.,2005,第1作者发表著作
（1）磁共振功能成像及临床应用,Functional Magnetic Resonance Imaging and Clinical Applications,人民军医出版社,2012-03,第1作者科研活动
科研项目
（ 1 ） 高端磁共振成像技术创新团队, 参与,省级,2011-01--2015-12（ 2 ） 基于磁共振氨基质子转移成像的急性脑中风缺血半影区定量pH研究, 主持,省级,2014-12--2016-12（ 3 ） 脑胶质瘤治疗后分子影像学评估, 参与,国家级,2015-01--2019-12（ 4 ） 多模态分子影像团队, 参与,国家级,2014-01--2015-12（ 5 ） 缺血存活心肌定量检测的磁共振化学交换饱和转移成像研究, 主持,国家级,2016-01--2019-12（ 6 ） 脑胶质瘤疗效精准评估的磁共振氨基质子转移成像研究, 主持,省级,2016-07--2018-06（ 7 ） 48 通道头颈联合血管线圈的研制, 主持,国家级,2016-07--2018-09（ 8 ） 基于磁共振氨基质子转移成像的缺血心肌损伤定量评估研究, 主持,省级,2017-05--2019-05（ 9 ） 广东省科技创新青年拔尖人才, 主持,省级,2017-06--2020-06（ 10 ） 基于磁共振氨基质子和弥散峰度联合成像的脑胶质瘤真假进展诊断研究, 主持,省级,2017-09--2020-08（ 11 ） 缺血缺氧脑损伤的磁共振pH定量成像研究, 主持,国家级,2019-01--2022-12（ 12 ） 磁共振pH定量成像无创监测胶质瘤乏氧微环境的关键技术研究, 主持,国家级,2019-01--2021-12参与会议
（1）Effect of b-value on DTI sensitivity in revealing myocardial structure degradation in rabbit models with acute myocardium infarctionY Wu, C Zou, W Liu, WQ Liao, EX Wu2012-05-05（2）Biexponential diffusion tensor analysis of myocardial structural alteration in rabbit models with myocardium infarctionY Wu, C Zou, W Liu, W Yang, K Jiang, EX Wu2012-05-05（3）Feasibility study of fast diffusion tensor imaging based on distributed compressed sensingY Wu, YJ Zhu, W Liu, QY Tang, YS An, EX Wu, L Ying, D Liang2012-05-05（4）Impact of b-value on DTI indices of left ventricular porcine myocardium: a preliminary studyY Wu, C Zou, L Zhang, W Liu, R Dai, N Zhang, X Liu2011-05-09（5）MR diffusion tensor investigation of transmural heterogeneity of myocardium structural remodeling in postinfarct porcine modelY Wu, EX Wu.2011-05-09（6）Diffusion tensor shape measurements of infarcted myocardium in porcine models using three phase geometric analysisY Wu, EX Wu2010-05-03（7）Investigation of myocardium structure of postinfarct porcine model using superquadric glyphsY Wu, EX Wu2010-05-03（8）Relation of myocardial fiber structure with cardiac wall motion using DTI and MR taggingY Wu, TY Chow, KX Cai, EX Wu2008-05-05（9）MR study of postnatal development of left ventricular myocardium structure and function in ratsY Wu, KX Cai, KH Cheung, EX Wu2008-05-05（10）Myocardium structural remodeling with relation of infarct location and size in porcine model using DTIY Wu, HF Tse, EX Wu2008-05-05指导学生
已指导学生杨沙沙硕士研究生083100-生物医学工程
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