所系名称
中国科学院南海海洋研究所，中国科学院热带海洋生物资源与生态重点实验室
性别
男
专业名称
海洋生物学
技术职务
副研究员
行政职务

Mail地址
chan1010@scsio.ac.cn
指导博士生总数
0
指导硕士生总数
0
通讯地址
广州市海珠区新港西路164号
目前博士生数
0
目前硕士生数
0
邮政编码
510301
研究方向
对虾卵巢发育调控与营养积累模式； 对虾抗病、抗逆良种选育；热带海参繁育与生态适应机制。

研究工作
1）利用比较基因组学、分子生物学手段，发掘对虾卵巢发育调控的新机制，建立“卵黄发生-运输-入卵”和“多器官、多激素调控”两个模型，对重要海水养殖经济品种凡纳滨对虾的卵巢发育模式进行了重新阐述，开发无损促进、延缓雌虾卵巢发育发明专利2项。
2）利用分子辅助育种、基因编辑育种技术对对虾抗病抗逆性状遗传改良，发掘多个抗逆、抗病性状重要功能基因，将优良性状分子标记应用于抗逆、抗病育种，作为重要完成人培育国家新品种“正金阳1号”凡纳滨对虾。
3）开发具有高经济价值热带海参新品种和新种质资源，首次突破重要珊瑚礁护礁种类玉足海参的全人工繁育和规模化育苗技术，并解析其生态适应机制。
获奖情况
1.广东省现代农业产业技术体系（虾蟹产业创新团队）病害防控与抗病育种岗位专家。
指导研究生情况
协助指导研究生16名，其中已毕业9名。

个人简介
教育经历：
2008/9–2013/2，香港大学，动物学，博士；
2004/9–2007/6，中山大学，水生生物学，硕士；
2000/9–2004/6，中山大学，生物科学，学士
科研经历：
2016/12-至今，中国科学院，南海海洋研究所，副研究员
2013/2-2016/12，中国科学院，南海海洋研究所，助理研究员
科研成果
发表论文（第一作者或通讯作者）
1. Chen T#, Rao YZ#, Li JX, Ren CH, Tang DS, Lin TH, Ji JT, Chen R*, Yan AF*. Two distinct C-type lysozymes in goldfish: Molecular characterization, antimicrobial potential, and transcriptional regulation in response to opposing effects of bacteria/lipopolysaccharide and dexamethasone/leptin. Int J Mol Sci. 2020 21(2):501
2. Wu X#, Chen T#, Huo D, Yu ZH, Ruan Y, Cheng CH, Jiang X, Ren CH*. Transcriptomic analysis of sea cucumber (Holothuria leucospilota) coelomocytes revealed the echinoderm cytokine response during immune challenge. BMC Genomics. 2020 21(1):306
3. Zhang XF#, Chen T#, Yan AF, Xiao J, Xie YL, Yuan J, Chen P, Wong AOL, Zhang Y*, Wong NK*. Poly(I:C) challenge alters brain expression of Oligodendroglia-related genes of adult progeny in a mouse model of maternal immune activation. Front Mol Neurosci. 2020 13:115
4. Li HP#, Chen T#, Sun HY, Wu XF, Jiang X, Ren CH* Functional characterisation of Holothuria leucospilota Fas-associated death domain in the innate immune-related signalling pathways. Innate Immunol. 2020 26(2):138-45
5. Ruan Y#, Wong NK#, Zhang X#, Zhu CH, Wu XF, Ren CH, Luo P, Jiang X, Ji JT, Wu XG*, Hu CQ*, Chen T* Vitellogenin receptor (VgR) mediates oocyte maturation and ovarian development in the Pacific white shrimp (Litopenaeus vannamei). Front Physiol. 2020 11:485
6. Wang L, Guo Q, Levy T, Chen T*, Wu XG*. Ovarian development pattern and vitellogenesis of ridgetail white prawn, Exopalaemon carinicauda. Cell Tissue Res. 2020 DOI: 10.1007/s00441-020-03223-8
7. Liu MM, Jiang XD, Chen AQ, Chen T*, Cheng YX, Wu XG*. Transcriptome analysis reveals the potential mechanism of dietary carotenoids improving antioxidative capability and immunity of juvenile Chinese mitten crabs Eriocheir sinensis. Fish Shellfish Immunol. 2020 104:359-73
8. Chen T, Wong MKH, Chan BCB, Wong AOL* Mechanisms for temperature modulation of feeding in goldfish and implications on seasonal changes in feeding behavior and food intake. Front Endocrinol. 2019 10:133
9. Li JX#, Chen T#, Rao YZ, Chen S, Wang B, Chen R, Ren CH, Liu L, Yang Y, Yu H, Tang DS, Yan AF*. Suppression of leptin-AI/AII transcripts by insulin in goldfish liver: A fish specific response of leptin under food deprivation. Gen Comp Endocrinol. 2019 283:113240
10. Li HP#, Chen T#, Sun HY, Wu XF, Jiang X, Ren CH* The first cloned echinoderm tumor necrosis factor receptor from Holothuria leucospilota: Molecular characterization and functional analysis. Fish Shellfish Immunol. 2019 93:542-50
11. Li HM, Ren CH, Jiang X, Cheng CH, Ruan Y, Zhang X, Huang W, Chen T*, Hu CQ*. Na+/H+ exchanger (NHE) in Pacific white shrimp (Litopenaeus vannamei): Molecular cloning, transcriptional response to acidity stress, and physiological roles in pH homeostasis. PLoS One. 2019 14(2):e**
12. Chen T#, Lin TH#, Li HM, Lu T, Li JX, Huang W, Sun HY, Jiang X, Zhang JQ, Yan AF, Hu CQ, Luo P*, Ren CH*. Heat shock protein 40 (HSP40) in Pacific white shrimp (Litopenaeus vannamei): Molecular cloning, tissue distribution and ontogeny, response to temperature, acidity/alkalinity and salinity stresses, and potential role in ovarian development. Front Physiol. 2018 9:1784
13. Chen T, Ren CH, Jiang X, Zhang LP, Li HM, Huang W*, Hu CQ*. Mechanisms for type-II vitellogenesis-inhibiting hormone suppression of vitellogenin transcription in shrimp hepatopancreas: Crosstalk of GC/cGMP pathway with different MAPK-dependent cascades. PLoS One. 2018 13(3): e**
Tian YS#, Chen T#, Luo P*, Huang W, Huo D, Yun L, Hu CQ, Cheng CH. A fibrinogen-related protein, Lv FREP2, from Litopenaeus vannamei facilitates the clearance of Vibrio harveyi. Fish Shellfish Immunol. 2018 78: 364-71
14. Huang W#, Huo D#, Yu ZH, Ren CH, Jiang X, Luo P, Chen T*, Hu CQ*. Spawning, larval development and juvenile growth of the tropical sea cucumber Holothuria leucospilota. Aquaculture. 2018 488:22-9
15. Huo D#, Jiang X#, Wu XF, Ren CH, Yu ZH, Liu JS, Li HM, Ruan Y, Wen J, Chen T*, Hu CQ*. First echinoderm trehalase from a tropical sea cucumber (Holothuria leucospilota): Molecular cloning and mRNA expression in different tissues, embryonic and larval stages, and under a starvation challenge. Gene. 2018 665:74-81
16. Cai YM#, Chen T#, Ren CH, Huang W, Jiang X, Gao Y, Huo D, Hu CQ*. Molecular characterization of Pacific white shrimp (Litopenaeus vannamei) sodium bicarbonate cotransporter (NBC) and its role in response to pH stress. Fish Shellfish Immunol. 2017 64: 226-33
17. Yan AF, Chen YF, Chen S, Li SS, Zhang Y, Jia JR, Yu H, Liu L, Liu F, Hu CQ, Tang DS*, Chen T*. Leptin stimulates prolactin mRNA expression in the goldfish pituitary through a combination of the PI3k/Akt/mTOR, MKK3/6/p38MAPK and MEK1/2/ERK1/2 signalling pathways. Int J Mol Sci. 2017 18(12):2781
18. Huang W, Ren CH, Li HM, Huo D, Wang YH, Jiang X, Tian YS, Luo P, Chen T*, Hu CQ*. Transcriptomic analyses on muscle tissues of Litopenaeus vannamei provide the first profile insight into the response to low temperature stress. PLoS One. 2017 12(6): e**
19. Chen T, Ren CH*, Wang YH, Luo P, Jiang X, Huang W, Chen C, Hu CQ*. Molecular cloning, inducible expression and antibacterial analysis of a novel i-type lysozyme (lyz-i2) in Pacific white shrimp, Litopenaeus vannamei. Fish Shellfish Immunol. 2016 54:197-203
20. Chen T, Ren CH, Wang YH, Gao Y, Wong NK, Zhang LP. Hu CQ*. Crustacean cardioactive peptide (CCAP) of the Pacific white shrimp (Litopenaeus vannamei): Molecular characterization and its potential roles in osmoregulation and freshwater tolerance. Aquaculture. 2016 451:405-12
21. Chen T#, Chen S#, Ren CH, Hu CQ, Tang DS, Yan AF*. Two isoforms of leptin in the White-clouds Mountain minnow (Tanichthys albonubes): Differential regulation by estrogen despite similar response to fasting. Gen Comp Endocrinol. 2016 225:174-84
22. Yan AF, Chen T*, Chen S, Tang DS, Liu F, Jiang X, Huang W, Ren CQ, Hu CQ. Signal transduction mechanism for glucagon-induced leptin gene expression in goldfish liver. Int J Biol Sci. 2016 12(12): 1544-54
23. Yan AF, Chen T*, Chen S, Ren CH, Hu CQ, Cai YM, Liu F, Tang DS. Goldfish leptin-AI and leptin-AII: function and central mechanism in feeding control. Int J Mol Sci. 2016 17(6):783
24. Chen T#, Wong NK#, Jiang X, Luo X, Zhang LP, Yang D, Ren CH*, Hu CQ. Nitric oxide as an antimicrobial molecule against Vibrio harveyi infection in the hepatopancreas of Pacific white shrimp, Litopenaeus vannamei. Fish Shellfish Immunol. 2015 42:114-20
25. Chen T#, Ren CH*, Li W, Jiang X, Xia JJ, Wong NK, Hu CQ. Calmodulin of the tropical sea cucumber: Gene structure, inducible expression and contribution to nitric oxide production and pathogen clearance during immune response. Fish Shellfish Immunol. 2015 45:231-8
26. Luo X#, Chen T#, Zhong M, Jiang X, Zhang LP, Ren CH, Hu CQ*. Differential regulation of hepatopancreatic vitellogenin (VTG) gene expression by two putative molt-inhibiting hormones (MIH1/2) in Pacific white shrimp (Litopenaeus vannamei). Peptides. 2015 68:58-63
27. Chen T#, Zhang LP, Wong NK, Zhong M, Ren CH*, Hu CQ. Pacific White Shrimp (Litopenaeus vannamei) vitellogenesis-inhibiting hormone (VIH) is predominantly expressed in the brain and negatively regulates hepatopancreatic vitellogenin (VTG) gene expression. Biol Reprod. 2014 90(3):47,1-10
28. Chen T, Tang ZG, Yan AF, Li WS*, Lin HR. Molecular cloning and mRNA expression analysis of two GH secretagogue receptor transcripts in orange-spotted grouper (Epinephelus coioides). J Endocrinol. 2008 199, 253-65
授权专利
陈廷、任春华、张吕平、黄文、江晓、胡超群，一种促进凡纳滨对虾卵巢发育的方法，中国发明专利，ZL6.2