所系名称
中国科学院南海海洋研究所，中国科学院热带海洋生物资源与生态重点实验室
性别
男
专业名称
海洋生物学
技术职务
责任研究员
行政职务

Mail地址
carlzyu@scsio.ac.cn
指导博士生总数
14
指导硕士生总数
18
通讯地址
广州市新港西路164号3号楼600
目前博士生数
3
目前硕士生数
3
邮政编码
510301
研究方向
贝类遗传学与育种研究、贝类功能基因与基因组学和 贝类生物多样性与比较线粒体基因组学。

研究工作
主要从事海洋贝类的遗传育种、分子生物学及功能基因组学研究，主要包括通过性状相关功能基因克隆、表达分析，功能和调控研究，为性状解析和良种培育提供可供利用的基因/基因组信息和工具；利用分子生物学、生物信息学、基因组、转录组、蛋白组学方法，研究贝类免疫、抗逆等性状表达的分子机理、解析基因组特征；通过实验生物学方法，进行牡蛎、砗磲等贝类的人工繁育研究，利用家系选择、群体选择、杂交和多倍体和分子辅助选育进行牡蛎等贝类优良品种培育。
获奖情况
1. 广东省劳动模范称号（2014）
2. 中国科学院广州分院“优秀研究生导师”称号（2014）

指导研究生情况
博士研究生：周梓华（2017）、ZOHAIB NOOR（2018）、周银银（2019）
硕士研究生：林玥（2017）、黎幸有（2018）、廖庆良（2019）
已培养博士研究生11名；硕士研究生15名

个人简介
学历和学位 Education history & Degrees
1979.09-83.06, 湖南师范大学, 生物学, 学士(BSc);
1983.09-86.06, 山东大学, 发育生物学, 硕士(MSc);
1994.09-97.06, 青岛海洋大学,海洋生物遗传学, 博士(Ph. D).
国外工作经历 Overseas Experience
1997.08-98.12，博士后 (Postdoctoral fellow),美国特拉华大学海洋学院 (College of Marine Studies, University of Delaware, USA)
2000.09-01.02，访问学者 (Visiting scholar),美国新泽西州立大学海洋与海岸科学学院 (IMCS, State University of New Jersey, USA)
2001.06-04.12，高级研究助理 (Senior research associate),美国新泽西州立大学海洋与海岸科学学院 (IMCS, State University of New Jersey, USA).
工作简历 Work history
1986.07-89.11助教，青岛海洋大学水产学院
1989.12-94.11 讲师，青岛海洋大学水产学院
1994.12-97.11 副教授，青岛海洋大学水产学院
1997.12-03.10 教授，青岛海洋大学水产学院
2005.01- 现在 责任研究员，中国科学院南海海洋研究所
学术兼职 Professional Affiliations
1. 广东海洋学会水生生物专业委员会副主任委员（2013-至今）
2. 中国贝类学会常务理事（2015-2019）
3. 世界牡蛎学会（World Oyster Soceity）执委/理事（2009-至今）
4. 广东省水产学会专家咨询委员会委员（2013-至今）
5. 《热带海洋学报》（2014-至今）
6. Aquatic Living Receources 副主编（Associate Editor）（2014-至今）

科研成果
论文发表
113. Yue Lin, Fan Mao, Xiangyu Zhang, Duo Xu, Zhiying He, Jun Li, Zhiming Xiang,Yang Zhang？, Ziniu Yu？ TRAF suppresses the apoptosis of hemocytes by activating Pellino in Crassostrea hongkongensis. Developmental & Comparative Immunology 2020, 103:103501
112. Yanping Qin, Yuehuan Zhang*, Riguan Mo, Yang Zhang, Jun Li, Yingli Zhou, Haitao Ma, Shu Xiao, Ziniu Yu* Influence of ploidy and environment on grow-out traits of diploid and triploid Hong Kong oysters Crassostrea hongkongensis in southern China. Aquaculture 2019, 507: 108-118
111. Yuehuan Zhang, Yanping Qin, Haitao Ma, Zihua Zhou, Shu Xiao, Ying Pan, Jun Li*., Ziniu Yu* Gametogenesis from the early history life stages of the Kumamoto oyster Crassostrea sikamea and their breeding potential evaluation. Frontiers in Physiology 2019, 10: 524
110. Xiangwei Wu, Yuehuan Zhang*, Shu Xiao, Yanping Qin, Haitao Ma, Ziniu Yu* Comparative studies of the growth, survival, and reproduction of diploid and triploid Kumamoto oyster, Crassostrea sikamea. Journal of the World Aquaculture Society 2019, 1-12
109. Haitao Ma, Yuehuan Zhang, Shu Xiao, Shixi Chen, Yang Zhang, Zhiming Xiang, Jun Li, Ziniu Yu* The complete mitochondrial genome of giant clam, Hippopus hippopus (Cardiidae: Tridacninae). Conservation Genetics Resources 2019, 11(3): 263-266
108. Xiangwei Wu, Xiande Liu, Ziniu Yu* Analysis of novel immune–related genes and microsatellite markers in the transcriptome of Paphia undulate. Journal of Oceanology and Limnology 2019, 37(4):1301-1316
107. Haitao Ma,Yuehuan Zhang,Yang Zhang,Shu Xiao,Chenghui Han,Shixi Chen, Ziniu Yu* The complete mitochondrial genome of the giant clam, Tridacna maxima (Tridacnidae Tridacna). Mitochondrial DNA Part B 2019, 4(1):1051-1052
106. Mao, F., Lin, Y., He, Z., Li, J., Xiang, Z., Zhang, Y*., Yu, Z* Dual roles of cystatin A in the immune defense of the pacific oyster, Crassostrea gigas. Fish and Shellfish Immunology 2018,75:190-197
105. Qin, Y., Xiao, S., Ma, H., Mo, R., Zhou, Z., Wu, X., Zhang Y*., Yu, Z* Effects of salinity and temperature on the timing of germinal vesicle breakdown and polar body release in diploid and triploid Hong Kong oysters, Crassostrea hongkongensis, in relation to tetraploid induction. Aquaculture Research 2018,49(11):3647-3657
104. Ma, H., Zhang, Y., Xiao, S., Chen, S., Zhang, Y., Xiang, Z., Li, J., Yu, Z* The complete mitochondrial genome of giant clam, Hippopus hippopus (Cardiidae: Tridacninae). Conservation Genetics Resources 2018,1-4
103. Zhou, Y., Mao, F., He, Z., Li, J., Zhang, Y., Xiang, Z., Zhang Y*., Yu, Z* The molecular mechanism underlying pro-apoptotic role of hemocytes specific transcriptional factor Lhx9 in Crassostrea hongkongensis. Frontiers in physiology 2018,9:612
102. Ma, H., Lin, L., Zhang, Y., Chen, S., Shi, W., Yu, Z* The complete mitochondrial genome sequence of the giant clam Tridacna derasa (Tridacnidae: Tridacna). Mitochondrial DNA Part B 2018,3(2),911-912
101. Mao, F., Lin, Y., Zhou, Y., He, Z., Li, J., Zhang, Y*., Yu, Z* Structural and functional analysis of interferon regulatory factors (IRFs) reveals a novel regulatory model in an invertebrate, Crassostrea gigas. Developmental & Comparative Immunology 2018,89:14-22
100. Li Jun, Zhang Yang, Zhang Yuehuan, Mao Fan, Xiao Shu, Xiang Zhiming, Ma Haitao, Yu Ziniu*. A Lysin motif (LysM)-containing protein from Hong Kong oyster, Crassostrea hongkongensis functions as a pattern recognition protein. Gene 2018,674:134-142
99. Qin, Y., Zhang, Y*., Ma, H., Wu, X., Xiao, S., Li, J., Yu, Z* Comparison of the biochemical composition and nutritional quality between diploid and triploid Hong Kong oysters, Crassostrea hongkongensis. Frontiers in physiology 2018,9:1674
98. Xiao, S., Wong, N. K., Li, J., Lin, Y., Zhang, Y., Ma, H., Zhang Y*., Yu, Z* Analysis of in situ transcriptomes reveals divergent adaptive response to hyper-and hypo-salinity in the Hong Kong Oyster, Crassostrea hongkongensis. Frontiers in physiology 2018,9:1491
97. Jun Li#, Yuehuan Zhang#, Fan Mao, Yue Lin, Shu Xiao, Zhiming Xiang, Haitao Ma, YangZhang*, ZiniuYu* The first morphologic and functional characterization of hemocytes in Hong Kong oyster, Crassostrea hongkongensis Fish and Shellfish Immunology 2018,81:423-429
96. Li J, Zhang Y, Zhang Y, Mao F, Xiang Z, Xiao S, Ma H, Yu Z. The first invertebrate NFIL3 transcription factor with role in immune defense identified from the Hong Kong oyster, Crassostrea hongkongensis Developmental and Comparative Immunology, 2017, 76: 1-8.
95. Li J, Zhang Y, Mao F, Tong Y, Liu Y, Zhang Y, Yu Z. Characterization and Identification of Differentially Expressed Genes Involved in Thermal Adaptation of the Hong Kong Oyster Crassostrea hongkongensis by Digital Gene Expression Profiling Frontiers in Marine Science, doi: 10.3389/fmars.2017.00112
94. Zhang Y, Li J, Zhang Y, Ma H, Xiao S, Xiang Z, Yu Z. Performance evaluation of reciprocal hybrids derived from the two brackish oysters, Crassostrea hongkongensis and C. sikamea in southern China Aquaculture 2017, 473: 310-316
93. Zhang Y, Su J, Li J, Zhang Y, Xiao S, Yu Z. Survival and growth of reciprocal crosses between two stocks of the Ho ng Kong oyster Crassostrea hongkongensis (Lam & Morton, 2003) in southern China Aquaculture Research, 2017, 48, 2344-2354.
92. Zhang Y, Li J, Qin Y, Zhou Y, Zhang Y, Yu Z. A comparative study of the survival, growth and gonad development of the diploid and triploid Hong Kong oyster, Crassostrea hongkongensis (Lam &Morton 2003) Aquaculture Research, 2017, 48, 2453–2462.
91. Zhang Y, Zhang Y, Li J, Wang Z, Yan X, Yu Z. Incomplete sterility of hybrids produced by Crassostrea hongkongensis female 3 Crassostrea gigas male crosses Aquaculture Research, 2017, 48, 1351–1358.
90. Zhang Y, Zhang Y, Li J, Yu Z. Morphological and molecular evidence of hybrid- dization events between two congeneric oysters, Crassostrea hongkongensis and C. ariakensis, in southern China Journal of Molluscan Studies, 2017, 83: 129-131.
89. Mao F, Li J, Zhang Y, Xiang Z, Zhang Y, Yu Z. Molecular cloning and functional analysis of tumor necrosis factor receptor-associated factor 6 (TRAF6) in C.gigas Fish & Shellfish Immunology, 2017, 68: 37-45.
88. Qu F, Xiang Z, Li J, Xiao S, Mao F, Qin Y, Zhou Y, Ma H, Yu Z. A molluscan extracellular signal-regulated kinase is involved in host response to immune challenges in vivo and in vitro Fish & Shellfish Immunology 2017,62:311-319.
87. Zhang, Y., Y. Zhang, J. Li, Z. Yu*, 2016, Morphological and molecular evidence of hybridization events between two congeneric oysters, Crassostrea hongkongensis and C. ariakensis , in southern China. J. Mollus. Stud. In press.
86. Zhang, Y., Y. Zhang, J. Li, S. Xiao, Z. Xiang, Z. Wang*, X. Yan, Z. Yu*, 2016, Artificial interspecific backcrosses between the hybrid of female Crassostrea hongkongensis × male C. gigas and the two parental species. Aquaculture, 450:95-101.
85. Zhang, Y., J. Su, J. Li, Y. Zhang, S. Xiao, Z. Yu*, 2016, Survival and growth of reciprocal crosses between two stocks of the Hong Kong oyster Crassostrea hongkongensis (Lam & Morton, 2003) in southern China. Aquaculture Research, DOI: 10.1111/are.13070
84. Zhang, Y., J. Li, Y. Qin, Y. Zhou, Y. Zhang, Z. Yu*, 2016, A comparative study of the survival, growth and gonad development of the diploid and triploid Hong Kong oyster, Crassostrea hongkongensis (Lam & Morton 2003). Aquaculture Research, DOI: 10.1111/are.13081
83. Li, J. , Y. Zhang, Y. Liu, Y. Zhang, S. Xiao, Z. Yu*, 2016, Co-expression of heat shock protein (HSP) 40 and HSP70 in Pinctada martensii response to thermal, low salinity and bacterial challenges. Fish Shellfish Immunol. 48: 239-243.
82. Zhang, Y., Y. Zhang, J. Li, S. Xiao, Z. Xiang, Z. Wang*, X. Yan, Z. Yu*, 2016，Artificial interspecific backcrosses between the hybrid of female Crassostrea hongkongensis × male C. gigas and the two parental species. Aquaculture, 450:95-101.
81. Tong, Y., Y. Zhang*, J. Huang, S. Xiao, Y. Zhang, Jun Li, J. Chen, Z. Yu*, 2015, Transcriptomics Analysis of Crassostrea hongkongensis for the Discovery of Reproduction-Related Gene. PLoS One, 10(8):e**.
80. Xu, F., Y. Zhang*, J. Li, Y. Zhang, Z. Xiang, Z. Yu, 2015, Expression and Function analysis of two Naturally Truncated MyD88 variants in the Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 45:510-516.
79. Xu, F., J. Li, Y. Zhang, X. Li, Y. Zhang*, Z. Xiang, Z. Yu*, 2015, CgIκB3, the third novel inhibitor of NF-kappa B (IκB) protein, is involved in the immune defense of the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 46:648-655.
78. Qu, F., Z. Xiang, F. Wang, Y. Zhang, J. Li, Y. Zhang, S. Xiao, Z. Yu*, 2015, Identification and function of an evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) from Crassostrea hongkongensis. Develop. Comp. Immunol.
77. Zhang, Y., Y. Zhang, Li J., Z. Wang*, X. Yan, Z. Yu*, 2015, Phenotypic trait of Crassostrea hongkongensis♀× C. angulata♂ hybrids in southern China. Aquaculture Research, DOI:10.1111/are.12787.
76. Qu, , F., Z. Xiang, F. Wang, Y. Zhang, Y. Tong, J. Li, Y. Zhang, Z. Yu*, 2015, A novel molluscan Fos gene with immune defense function identified in the Hong Kong oyster, Crassostrea hongkongensis. Develop. Comp. Immunol. 51:194-201.
75. Li, J. , Y. Zhang, Y. Zhang, Y. Liu, Z. Xiang, F. Qu, Z. Yu, 2015, Cloning and characterization of three suppressors of cytokine signaling (SOCS) genes from the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 44: 525–532.
74. Zhang, Y., J. Sun , H. Mu , J. Li ,Y. Zhang , F. Xu , Z. Xiang, P Y. Qian , J. W. Qiu* and Z. Yu*, 2015, Proteomic basis of stress responses in the gills of the Pacific oyster Crassostrea gigas. J. Proteome Res. 14, 304？317.
73. Qu, F., Xiang, Z., F. Wang, L. Qi, F. Xu, S. Xiao and Z. Yu*, 2015, Prostaglandin E receptor 4 (PTGER4) involved in host protection against immune challenge in oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 42: 316–324.
72. Xiang, Z., F. Qu, F. Wang, Y. Tong, S. Xiao, J. Li, Y. Zhang and Z. Yu*, 2015, ChBax/Bak as key regulators of the mitochondrial apoptotic pathway: Cloned and characterized in Crassostrea hongkongensis. Fish Shellfish Immunol. 42:225-232.
71. Zhang, Y., Y. Zhang, Z. Wang*, X. Yan and Z. Yu*, 2014, Phenotypic trait analysis of diploid and triploid hybrids from female Crassostrea hongkongensis × male C. gigas. Aquaculture 434: 307-314.
70. Qu, F., Xiang Z., Zhang Y, Li J., Zhang Y, Z. Yu*, 2014, The identification of the first molluscan Akirin2 with immune defense function in the Hong Kong oyster Crassostrea hongkongensis. Fish Shellfish Immunol. 41: 455-465.
69. Xiang, Z., F. Qu, J. Li, F. Wang, Y. Zhang and Z. Yu*, 2014, Characteristic and functional analysis of a ficolin-like protein from the oyster Crassostrea hongkongensis. Fish Shellfish Immunol. 40: 514-523.
68. Li, J., Y. Zhang, Y. Zhang, Z. X.iang, Y. Tong, F. Qu and Z. Yu*, 2014, Genomic characterization and expression analysis of five novel IL-17 genes in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 40: 455-465.
67. Zhang, Y., F. Yu, J. Li, Y. Tong, Y. Zhang and Z. Yu*, 2014, The first invertebrate RIG-I-like receptor (RLR) homolog gene in the pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 40: 466-471.
66. Zhang, Y., J. Li, F. Yu, Y. Tong, Y. Zhang, Z. Xiang and Z. Yu*, 2014, Identification and functional characterization of SIMPL in Crassostrea gigas reveals its ancient origin and involvement in the regulation of Rel/NF-κB transcription activity. Fish Shellfish Immunol. 40: 239-244.
65. Xia, J. X. Wu, S. Xiao, Z. Yu*, 2014, Mitochondrial DNA and morphological identification of a new cupped oyster species Crassostrea dianbaiensis (Bivalvia: Ostreidae) in the South China Sea. Aquat. Living Resour. 27: 41-48.
64. Qu, F., Xiang, Z., Z. Yu*, 2014, The first molluscan acute phase serum amyloid A (A-SAA) identified from oyster Crassostrea hongkongensis: Molecular cloning and functional characterization. Fish Shellfish Immunol. 39: 145-151.
63. Huang, J., Y. Zhang, J. Li, Z. Yu*, 2014, Development of SNP markers in Crassostrea hongkongensis based on the next-generation sequencing and high resolution melting analysis. Conservation Genet Resour. 6:559–562.
62. Xiang, Z., F. Qu, L. Qi, Y. Tong, J. Li, S. Xiao, Z. Yu*, 2014, Cloning and characterization of an apoptosis-related DNA fragmentation factor (DFF) from oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 38: 119–126.
61. Wu, X., S. Xiao, X. Li, L. Li, W. Shi, Z. Yu*, 2014, Evolution of the tRNA gene family in mitochondrial genomes of five Meretrix clams (Bivalvia, Veneridae). Gene 533(1): 439–446.
60. Xiang, Z., F. Qu, L. Qi, Y. Zhang, S. Xiao, Z. Yu*, 2014, A novel ortholog of serum response factor (SRF) with immune defense by a novel ortholog of serum response factor (SRF) in C. hongkongensis. Fish Shellfish Immunol. 36: 75-82.
59. Xiang, Z., F. Qu, J. Li, L. Qi, Y. Zhang, Z. Yu*, 2014, Activator Protein-1 (AP-1) and Response to Pathogen Infection in the Hong Kong Oyster (Crassostrea hongkongensis). Fish Shellfish Immunol. 36: 83-89
58. Wu, X., S. Xiao, Z. Yu*, 2013, Mitochondrial DNA and morphological identification of Crassostrea zhanjiangensis sp. nov. (Bivalvia: Ostreidae): a new species in Zhanjiang, China. Aquat. Living Resour. 26(4): 273-280.
57. Xiao, S., X. Wu, L. Li, Z. Yu*, 2013, Complete mitochondrial genome of the Olympia oyster Ostrea lurida (Bivalvia, Ostreidae). Mitochondrial DNA DOI: 10.3109/**.2013.834428 56. Zhang, Y., X. He, F. Yu, Z. Xiang, J. Li, K. L. Thorpe, Z. Yu*. 2013, Characteristic and functional analysis of Toll-like receptors (TLRs) in the lophotrocozoan, Crassostrea gigas, reveals ancient origin of TLR-mediated innate immunity. PLoS One. 8(10): e76464.
55. Wu, X., X. Li, Z. Yu*, 2013, The mitochondrial genome of the scallop Mimachlamys senatoria (Bivalvia, Pectinidae). Mitochondrial DNA DOI: 10.3109/**.2013.823181
54. Xiang, Z., F. Qu, L. Qi,Y. Zhang, Z. Yu*, 2013, Cloning, characterization and expression analysis of a caspase-8 like gene from the Hong Kong oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 36:1797-1803.
53. Li, L., X. Wu and Z. Yu*, 2013, Genetic diversity and substantial population differentiation in Crassostrea hongkongensis revealed by mitochondrial DNA. Mar. Genomics. 11:31-37.
52. Ginger, W. K. Ko, B. S. Vera Chan, R. Dineshram, K. S. Dennis Choi, J. Adela Li, Z. Yu, V. Thiyagarajan. 2013, Larval and post-larval stages of Pacific oyster (Crassostrea gigas) are resistant to elevated CO2. PLoS One, 8(5): e64147
51. Li, J., Y. Zhang, Z. Xiang, S. Xiao, F. Yu, Z. Yu*, 2013, High mobility group box 1 can enhance NF-κb activation and act as a pro-inflammatory molecule in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 35:63-70.
50. Dineshram, R. V. Thiyagarajan, A. Lane, Z. Yu, S. Xiao, Priscilla T. Y. Leung. 2013, Elevated CO2 alters larval proteome and its phosphorylation status in the commercial oyster, Crassostrea hongkongensis. Mar Biol. 160 (8):2189-2205.
49. Zhang, Y., J. Li, F. Yu, X. He and Z. Yu*, 2013, Allograft inflammatory factor-1 stimulates hemocyte immune activation by enhancing phagocytosis and expression of inflammatory cytokines in Crassostrea gigas. Fish Shellfish Immunol. 34:1071-1077. 5
48. Zhang, Y., Z. Yu*, 2013, The first evidence of positive selection in peptidoglycan recognition protein (PGRP) genes of Crassostrea gigas. Fish Shellfish Immunol. 34:1352-1355.
47. Li, J., J. Chen, Y. Zhang and Z. Yu*, 2013, Expression of Allograft inflammatory factor-1 (AIF-1) in response to bacterial challenge and tissue injury in the pearl oyster, Pinctada martensii. Fish Shellfish Immunol. 34:365- 371.
46. Dineshram R, Wong K, Xiao S, Yu Z, Qian PY, Thiyagarajan V. 2012, Analysis of Pacific oyster larval proteome and its response to high-CO2. Mar. Pollution Bull. 64 (10): 2160-7.
45. Wu, X., X. Li, L. Li, Z. Yu*, 2012, A unique tRNA gene family and a novel, highly expressed ORF in the mitochondrial genome of the silver-lip pearl oyster, Pinctada maxima (Bivalvia: Pteriidae). Gene 510: 22-31.
44. Yu, F., Y. Zhang and Z. Yu*, 2012, Characteristics and expression patterns of the Lipopolysaccharide-induced TNF-α factor (LITAF) gene family in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 33:899-908. 5
43. Wu, X., X. Li, L. Li, X. Xu, J. Xia, Z. Yu*, 2012, New features of Asian Crassostrea oyster mitochondrial genomes: a novel alloacceptor tRNA gene recruitment and two novel ORFs. Gene 507: 112-118. 3
42. Li, X., X. Wu and Z. Yu*, 2012, Complete mitochondrial genome of the Asian green mussel Perna viridis (Bivalvia, Mytilidae). Mitochondrial DNA. 23(5): 358-60.
41. Xu, X., X. Wu and Z. Yu*, 2012, Comparative studies of the complete mitochondrial genomes of four Paphia clams and reconsideration of subgenus Neotapes (Bivalvia: Veneridae). Gene 494:17-23. 10
40. Fu, D., Y. Zhang, S. Xiao and Z. Yu*, 2011, The first homolog of a TRAF7 (TNF receptor-associated factor 7) gene in a mollusk, Crassostrea hongkongensis. Fish Shellfish Immunol. 31: 1208-1210.
39. Li, L., Xiao S. and Z. Yu*, 2011, Development of twenty-six microsatellite loci from Crassostrea hongkongensis and cross-species amplification in two closely related species. J Genetics 90 (2): e58-61.
38. Yu Z.*, X. He, F. Yu and Y. Zhang, 2011, Two superoxide dismutase (SOD) with different subcellular localizations involved in innate immunity in Crassostrea hongkongensis. Fish Shellfish Immunol. 31: 533-539. 10
37. Chen J, Xiao S, Z. Yu*, 2011, Cloning of a novel glutathione S-transferase 3 (GST3) gene and expression analysis in pearl oyster, Pinctada martensii. Fish Shellfish Immunol. 31: 823-830. 7
36. Chen, J., Xiao S., Z. Yu*, 2011, Molecular cloning, characterization and expression analysis of receptor for activated C kinase 1 (RACK1) from pearl oyster (Pinctada martensii) challenged with bacteria and exposed to cadmium. Fish Shellfish Immunol. 31: 781-787.
35. Zhang, Y., D. Fu, F. Yu, Q. Liu, Z. Yu*, 2011, Two catalase homologs are involved in host protection against bacterial infection and oxidative stress in Crassostrea hongkongensis. Fish Shellfish Immunol. 31:894-903. 4
34. He, X., Y. Zhang, F. Yu, Z. Yu*, 2011, A novel sialic acid binding lectin from Hong Kong oyster (Crassostrea hongkongensis) with anti-bacterial activity. Fish Shellfish Immunol. 31:1247-1250. 5
33. Fu, D., J. Chen, Y. Zhang, Z. Yu*, 2011, Cloning and expression of a heat shock protein (HSP) 90 gene in the haemocytes of Crassostrea hongkongensis under osmotic stress and bacterial challenge. Fish Shellfish Immunol. 31: 118-125. 20
32. Zhang, Y., X. He, Z. Yu*, 2011, Two homologues of inhibitor of NF-kappa B (IκB) are involved in the immune defense of the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol 30: 1354-1361. 18
31. He, X., Y. Zhang, Z. Yu*, 2011, An Mpeg (Macrophage expressed gene) from the Pacific oyster Crassostrea gigas: molecular characterization and gene expression. Fish Shellfish Immunol. 30:870-876. 10
30. Zhang, Y., X. He, X. Li, D. Fu, Chen, J., Z. Yu*, 2011, The second bactericidal permeability increasing protein (BPI) and its revelation of the gene duplication in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 30:954-963. 10
29. Chen, J., Xiao S., Z. Yu*, 2011, F-type lectin involved in defense against bacterial infection in the pearl oyster (Pinctada martensii). Fish Shellfish Immunol. 30: 750-754. 11
28. Fu, D., Y. Zhang, Z. Yu*, 2011, Cloning and expression analysis of an ubiquitin gene (UbL40) in the haemocytes of Crassostrea hongkongensis under bacterial challenge. Chinese J. Oceano. Limno. 29 (1):80-86.
27. He, X., Y. Zhang, X. Wu; S. Xiao; and Z. Yu*, 2011, Cloning and characterization of two ferritin subunit genes from bay scallop, Argopecten irradians (Lamarck 1819). Mol. Biol. Rep. 38: 2125-2132. 6
26. Xiao, S., H. Ma, Z. Yu, 2011, Development of 20 novel microsatellite markers in the Hong Kong oyster, Crassostrea hongkongensis. Conserv. Genet. Res. 3:413-415.
25. Xu, X., X. Wu, Z. Yu*, 2010, The mitogenome of Paphia euglypta (Bivalvia: Veneridae) and comparative mitogenomic analyses of three venerids. Genome 53 (12): 1041–1052. 8
24. Li, L. and Z. Yu*, 2010, Isolation and characterization of twenty-four microsatellite loci in oyster Crassostrea hongkongensis. Conserv. Genet. Res. 2:93–96.
23. Wu, X., X. Xu, Z. Yu*, X. Kong, Z. Wei, J. Xia, 2010, Comparison of seven Crassostrea mitogenomes and phylogenetic analyses. Mol. Phylogenet. Evol. 57: 448–454. 14
22. Yu, Z*., Y. Wang and D. Fu, 2010, Development of Fifty-one novel EST-SSR loci in the Pacific oyster, Crassostrea gigas by data mining from the public EST database. Conserv. Genet. Res. 2:13–18.
21. He, X., Y. Zhang and Z. Yu*, 2010, In silico cloning, expression of Rieske-like apoprotein gene and protein subcellular localization in the Pacific oyster, Crassostrea gigas. Mol. Biol. Rep. 37:3259–3264.
20. Kong, X., X. Dong, Y. Zhang, W. Shi, Z. Wang and Z. Yu, 2009, A novel rearrangement in the mitochondrial genome of tongue sole, Cynoglossus semilaevis: control region translocation and a tRNA gene inversion. Genome 52: 975-984.
19. Ma, H. and Z. Yu*, 2009, Isolation and characterization of twenty-three microsatellite loci in the noble scallop, Chlamys nobilis. Conserv. Genet. Res. 1: 131-134.
18. Wu, X, X. Xu, Z. Yu*, J. Xia and X. Kong, 2009. Comparative mitogenomic analyses of three scallops (Bivalvia: Pectinidae) reveal high level variation of genomic organization and a diversity of transfer RNA gene sets. BMC Res. Note 2, 69: 7 pp.
17. Li, Y., X. Kong, Z. Yu et al., 2009, Genetic diversity and historical demography of Chinese shrimp Feneropenaeus chinensis in Yellow Sea and Bohai Sea based on mitochondrial DNA analysis. Afr. J. Biotechnol. 8 (7): 1193-1202.
16. Wang, Y., Z. Yu* and Z. Liu, 2009, Isolation and characterization of twelve microsatellite loci in the noble scallop, Chlamys nobilis. Aquac. Res. 40: 744-747.
15. Ma, H. and Z. Yu*, 2009, Development of twenty-two polymorphic microsatellite loci in the noble scallop, Chlamys nobilis. Conserv. Genet. 10: 1587-1590.
14. Xia, J. X. He and Z. Yu*, 2009, Isolation and characterization of fourteen novel microsatellite loci in the Hong Kong oyster, Crassostrea hongkongensis Conserv. Genet. 10: 1829-1832.
13. Xia, J. and Z. Yu*, 2009, Identification of seven Crassostrea oysters from the South China Sea using PCR- RFLP analysis. J. Mollus. Stud. 75: 139-146. 12
12. Yu, Z., Z. Wei, X. Kong, W. Shi, 2008, Complete mitochondrial DNA sequence of oyster Crassostrea hongkongensis - a case of “Tandem duplication -random loss” for genome rearrangement in Crassostrea? BMC Genomics 9, 477: 13 pp.
11. Wang, Y., R. Ren and Z. Yu*, 2008, Bioinformatic mining of EST-SSR loci in the Pacific oyster, Crassostrea gigas. Anim. Genet. 39: 287-289.
10. Yu, Z.*, X. Kong, X. Wei, 2007, Application of the first internal transcribed spacer (ITS-1) of ribosomal DNA as a molecular marker to population analysis in Zhikong scallop, Chlamys farreri. Acta Oceanol. Sinica. 26: 93-100.
9. Kong, X., J. Yu, Z. Yu* et al., 2007, Comparative analysis of 5’-end sequence of mitochondrial control region of six flatfish species (Pleuronectidae) from the Yellow Sea and phylogentic analysis of Pleuronectiformes. Raffles Bull. Zool. Suppl. 14: 111-120.
8. Yu, Z. and X. Guo, 2006, Identification and mapping of disease-resistance QTLs in the Eastern oyster, Crassostrea virginica Gmelin. Aquaculture 54:160-170.
7. Yu, Z., Kong, X., Y. Jiang et al., 2005, Mitochondrial DNA sequence variation of Japanese anchovy (Engraulis japonicus) from the Yellow Sea and East China Sea. Fish. Sci. 71: 299-307.
6. Zhang, L., X. Kong, Z. Yu* et al., 2004, A survey of genetic changes and search for sex-specific markers by AFLP and SAMPL in a breeding program of Chinese shrimp (Penaeus chinensis). J. Shellfish Res. 23: 897-902.
5. Lapègue, S., F. M. Batista, S. Heurtebise, Z. Yu and P. Boudry, 2004, Evidence for the presence of the Portuguese oyster, C. angulata, in Northern China. J. Shellfish Res. 23: 759-764.
4. Yu, Z. and X. Guo, 2004, Genetic analysis of selected strains of the Eastern oyster (Crassostrea virginica Gmelin) using AFLP and microsatellite markers. Mar. Biotechnol. 6:575-586.
3. Yu, Z. and X. Guo, 2003, Genetic linkage map of the Eastern oyster, Crassostrea virginica Gmelin. Biol. Bull. 204: 327-338.
2. Yu, Z.*, X. Kong, L. Zhang, X. Guo and J. Xiang, 2003, Taxonomic status of four Crassostrea oysters from China as inferred from mitochondrial DNA sequences. J. Shellfish Res. 22: 31-38. 1. Kong, X., Z. Yu*, Y. Liu and L. Chen, 2003, Intraspecific genetic variation in mitochondrial 16S ribosomal gene of Zhikong scallop Chlamys farreri. J. Shellfish Res. 22: 655-660.
授权专利
1. 喻子牛、夏建军. 华南沿海七种巨蛎属牡蛎的PCR-RFLP鉴别方法. 授权日: 2010.07.21专利号: ZL 5.7
2. 喻子牛、王艳红. 太平洋牡蛎EST微卫星标记的筛选方法. 授权日: 2009.08.26专利号: ZL 8.8
3. 王艳红、喻子牛. 华贵栉孔扇贝微卫星标记的构建方法. 授权日: 2009.10.21专利号: ZL 9.2
4. 张跃环、肖述、张扬、喻子牛. 一种华南沿海香港牡蛎室内大规模人工繁育方法. 授权日: 2015.07.29专利号: ZL 9.0
5. 张跃环、肖述、喻子牛. 一种适用于华南沿海香港牡蛎稚贝生态育成的方法. 授权日: 2015.05.20专利号: ZL 0.2
6. 张跃环、肖述、张扬、喻子牛. 一种僧帽牡蛎的人工繁育方法. 授权日: 2016.01.13专利号: ZL 3.4
7. 肖述、张跃环、张扬、喻子牛. 一种提高香港牡蛎天然采苗效率的预报方法. 授权日: 2015.09.30专利号: ZL 1.9
8. 张跃环、肖述、张扬、喻子牛. 一种适用于华南沿海盐度渐变式熊本牡蛎室内大规模人工繁育新方法. 授权日: 2016.01.13专利号: ZL 6.4
9. 张跃环、肖述、向志明、李军、张扬、喻子牛. 一种以左壳放射嵴数目为标记的熊本牡蛎制种方法. 授权日: 2015.09.02专利号: ZL 0.6
10. 张跃环、喻子牛、肖述、张扬. 一种以鳃孔游离度为标记的香港牡蛎制种方法. 授权日: 2015.09.02专利号: ZL 9.7
11. 张跃环、肖述、李琼珍、张扬、李军、喻子牛. 一种香港牡蛎薄壳新品系的制种方法. 授权日: 2015.07.15专利号: ZL 3.2
12. 张跃环、肖述、李琼珍、张扬、李军、喻子牛. 一种香港牡蛎耐高盐新品系的制种方法. 授权日: 2015.08.19专利号: ZL 1.X
13. 张跃环、喻子牛、苏家齐、张扬、李军、李琼珍. 一种生产香港牡蛎全三倍体的时间点定量处理方法. 授权日: 2016.01. 20专利号: ZL 0.9
14. 张跃环、苏家齐、肖述、喻子牛. 一种获取牡蛎属间远缘杂种的方法. 授权日: 2015.05.20专利号: ZL 8.4
15. 张跃环、喻子牛、肖述、张扬. 一种香杂回交牡蛎新品系的培育方法. 授权日: 2015.12.02专利号: ZL 3.3
16. 张跃环、喻子牛、肖述、张扬. 一种香长杂交牡蛎品系的培育方法. 授权日: 2016.01.20专利号: ZL 2.6
17. 张跃环、喻子牛、肖述、张扬. 一种长杂回交牡蛎品系的培育方法. 授权日: 2016.01.20专利号: ZL 0.1
18. 张跃环、肖述、张扬、喻子牛. 一种牡蛎远缘杂种不育的育性恢复方法. 授权日: 2015.09.02专利号: ZL 9.2
19. 张跃环、喻子牛、肖述、张扬. 一种固定牡蛎远缘杂种回交优势的育种方法. 授权日: 2016.05.11专利号: ZL 5.7
20. 张跃环、喻子牛、肖述、张扬. 一种牡蛎种间核质互换品系的制种方法. 授权日: 2015.09.23专利号: ZL 0.0
21. 张跃环、肖述、张扬、李军、向志明、喻子牛. 一种利用冰点前临界低温长期保存香港牡蛎眼点幼虫的方法. 授权日: 2015.10. 28专利号: ZL 2.1
22. 肖述、张跃环、李琼珍、喻子牛. 一种水泥贝壳复合式香港牡蛎固着基制作及应用方法. 授权日: 2015.10.28专利号: ZL 3.7
23. 张跃环、肖述、向志明、李军、张扬、李琼珍、喻子牛. 一种水泥结式香港牡蛎固着基制作及其应用方法. 授权日: 2015.12. 09专利号: ZL 0.6
24. 肖述、张跃环、李琼珍、张扬、李军、喻子牛. 一种防御香港牡蛎大规模死亡的逐级淡泡方法. 授权日: 2015.08.19专利号: ZL 5.8
25. 张跃环、肖述、李琼珍、张扬、李军、喻子牛. 一种回避香港牡蛎冬季大规模死亡的露空防御方法. 授权日: 2016.01. 13专利号: ZL 0.1
26. 张扬、张跃环、李军、喻子牛. 一种新型特异结合LPS的贝类模式识别受体LRRP. 授权日: 2016.01.13专利号: ZL 3.5
27. 张扬、徐凤娇、张跃环、李军、喻子牛.一种新型贝类促进血淋巴细胞吞噬作用的调理素DCP. 授权日: 2016.05. 11专利号: ZL 9.X
28. 向志明、瞿符发、肖述、喻子牛. 一种血清淀粉样蛋白A及其编码基因和应用. 授权日: 2015.12. 02专利号: ZL 3.2
29. 一种判断香港牡蛎存活力的方法，ZL 0.2，肖述，喻子牛，向志明，马海涛，张跃环，符政君
30. 一种有效避免砗磲贝自体受精的化学方法，ZL 20**，肖述，喻子牛，张跃环，马海涛，向志明
31. 一种砗蠔人工繁育方法，ZL 2.X，肖述，张跃环，喻子牛
32. 一种砗磲人工繁育方法，ZL 9.9，张跃环，肖述，喻子牛
33. 一种双黑壳熊本牡蛎品系的制种方法，ZL 20**，张跃环，喻子牛，秦艳平，李军，张扬