个人简介


范瑞芳


性别：女
职称：教授
学历：博士
学科：生态毒理学与环境毒理学
工作电话：
电子邮件：**@m.scnu.edu.cn
相关链接：
简历更新：2020-04-26

个人简历


华南师范大学生命科学院教授，博士研究生导师，1991年本科毕业于河南师范大学，2000年硕士毕业于北京理工大学，2007年从中科院广州地球化学所博士毕业，2010年9月-2012年3月获国家留学基金委资助，赴美国加州公共卫生局（California Department of Public Health）访学一年半。华南师范大学-番禺中心医院基础与转化医学联合实验室客座教授，广东省环境科学学会生态毒理学与环境毒理学分会委员，广东省环境诱变剂协会理事，国家自然科学基金、科技部、教育部以及广东省等国家和省级项目评审专家，长期担任Environment International, Environmental Science & Technology, Toxicology等国际知名杂志的审稿人。
长期从事环境持久性有机污染物人群暴露监测、环境污染物毒理及对人体健康的影响机制研究。主持国家和省部级基金10余项，在国内外发表中英文论文70余篇，其中60篇被SCI及EI收录，引用合计700余次，H指数为17。曾获得2014年度华南师范大学科研工作优秀奖等荣誉，培养的多名研究生获得“国家奖学金”、“广东省优秀硕士学生”以及校级“优秀硕士论文”等奖励和荣誉称号；2019年指导本科生获得“第15届《挑战杯》广东大学生课外学术科技作品竞赛二等奖”。




教育经历


1991年本科毕业于河南师范大学2000年硕士毕业于北京理工大学2007年从中科院广州地球化学所博士毕业

研究方向


（1）环境有机污染物污染与人体健康的关系以环境中常见的有机污染物，如多环芳烃、挥发性有机污染物、环境雌激素为研究对象，进行普通以及职业暴露人群的暴露监测，通过环境卫生流行病学研究方法寻找环境污染物暴露与人群健康有害结局之间的关系。（2）环境污染物的毒理效应与机制研究以大鼠、小鼠以及细胞为模型，研究多酚类环境雌激素的长期环境对学习记忆以及行为学改变的影响及其分子机制。

讲授课程


现代仪器分析技术，研究生，必修课物理化学，本科生，必修课

承担课题


承担课题(近5年)：[1]国家自然科学基金（**），2018.01-2021.12，64万元，主持，在研。[2]国家自然科学基金重点项目（**），2018.01-2022.12，60/323万元，子课题负责人，在研。[3]国家自然科学基金 (**)，2015.01-2018.12, 87万元，主持，已结题。[4]广州市科技计划项目 (7)， 2015.06-2018.06，20万，主持，已结题。[5]广东省自然科学基金 (S20**)， 2013.10-2015.10，5万元，主持，已结题。

论文专著


论文专著(^#第一作者，^*通讯作者，近5年)：
按照以下格式，按照时间倒序列出，论文中所有作者都要列出。
(1) Haibin Zhang, Zhouyu Wang, Lingxue Meng, Hongxuan Kuang, Jian Liu, Xuejing Lv, Qihua Pang, Ruifang Fan^*, Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations, Toxicology, 2020, 432:152393.
(2) Hongxuan Kuang, Yanyan Dai, Yonghong Li, Caihui Cha, Wenhui Jiang, Qihua Pang, Haibin Zhang, Ruifang Fan*. The association among blood BPDE-DNA adducts, serum interleukin-8 (IL-8) and overall DNA damage for children with pulmonary disease. International Journal of Environmental Health Research, 2019, 1-12. (SCI, IF₂₀₁₈=1.465)
(3) Hongxuan Kuang, Yonghong Li, Wenhui Jiang, Peiqiong Wu, Jianhua Tan, Haibin Zhang, Qihua Pang, Ruifang Fan*. Simultaneous determination of urinary 31 VOC metabolites，8-hydroxy-2′-deoxyguanosine and trans-3′-hydroxy-cotinine by UPLC-MS/MS: The effect of isotoped internal standards on elimination of matrix effect, Analytical and Bioanalytical Chemistry, 2019, 411:7841-7855. (SCI, IF₂₀₁₈=3.286)
(4) Haibing Zhang, Kuanghong Xuan, Yifan Luo, Shuhua Liu, Lingxue Meng, Qihua Pang, Ruifang Fan*. Low-dose bisphenol A exposure impairs learning and memory ability with alterations of neuromorphology and neurotransmitters in rats, Science of the Total Environment, 2019, 697:134036. （SCI, IF₂₀₁₈=5.589）
(5) Qihua Pang#, Yanru Li#, Lingxue Meng, Guanyong Li, Zhiwei Luo, Ruifang Fan*. Neurotoxicity of BPA, BPS and BPB for the hippocampal cell line (HT-22): an implication for the replace of BPA in plastics，Chemosphere, 2019, 226:545-552. (SCI, IF₂₀₁₈=5.108, 2区)
(6) Laiguo Chen, Guocheng Hu, Ruifang Fan*, Yanshan Lv, Yanyan Dai, Zhencheng Xu*. Association of PAHs and BTEX exposure with lung function and respiratory symptoms among non-occupational population near the coal-chemical industry in Northern China. Environment International, 2018, 120:480-488. (SCI, IF₂₀₁₈=7.943, 1区)
(7) Yanru Li, Haibin Zhang, Hongxuan Kuang, Ruifang Fan*, Caihui Cha*, Guanyong Li, Zhiwei Luo, Qihua Pang. Relationship between Bisphenol A exposure and Attention-deficit/ hyperactivity disorder: A case-control study for primary school children in Guangzhou, China. Environmental Pollution, 2018, 235:141-149. (SCI, IF₂₀₁₈=5.714, 2区)
(8) Yuanxiu Zhou, Zhouyu Wang, Minghan Xia, Siyi Zhuang, Xiaobing Gong*, Jianwen Pan, Chuhua Li, Ruifang Fan*, Qihuang Pang, Shaoyou Lu. Neurotoxicity of low bisphenol A (BPA) exposure for young male mice: An implication for children exposed to environmental level of BPA, Environmental Pollution, 2017, 229:40-48. (SCI, IF₂₀₁₇=4.358, 2区)
(9) Yanshan Lv#, Shaoyou Lu#, Yanyan Dai, Caiyan Rui, Yongjun Wang, Yanru Li, Yuanxiu Zhou, Qihua Pang, Ruifang Fan^*. Higher dermal exposure of cashiers to BPA and its association with DNA oxidative damage, Environment International, 2017, 98:69-74. (SCI, IF₂₀₁₇=7.297, 1区).
(10) Yanshan Lv, Caiyan Rui, Yanyan Dai, Qihua Pang, Yanru Li, Ruifang Fan^*, Shaoyou Lu^*. Children exposure to BPA through dust and the association of urinary BPA, triclosan with oxidative stress in Guangzhou, China. Environmental Science: processes & impact, 2016, 18: 1492-1499. (SCI, IF₂₀₁₆=2.592)
(11) Shaoyou Lu, Lu Ren, Jianzhang Fang, Jiajia Ji, Guihua Liu, Jianqing Zhang, Huimin Zhang, Ruorong Luo, Kai Lin, Ruifang Fan*. Trace elements can increase urinary 8-hydroxy-2’-deoxyguanosine level: a case study of college students in Guangzhou, China. Environmental Science and Pollution Research, 2016, 23:8484–8491. (SCI, IF₂₀₁₆=2.741)
(12) Junnan Li#, Shaoyou Lu#_, Guihua Liu, Yuanxiu Zhou, Yan Shan Lv, Jianwen She, Ruifang Fan*. Co-exposure to polycyclic aromatic hydrocarbons, benzene and toluene and their dose-effects on oxidative stress damage in kindergarten-aged children in Guangzhou, China. Science of the Total Environment, 2015, 524-525: 74-80. (SCI, IF₂₀₁₅=4.099, 2区).
(13) Ruifang Fan*, Biyan Zeng, Xiaosu Liu, Chao Chen, Qinwei Zhuang, Yongjun Wang, Mingli Hu, Yanshan Lv, Junnan Li, Yuanxiu Zhou, Zhi Yuan (William) Lin. Levels of bisphenol-A in different paper products in Guangzhou, China and assessment of human exposure via dermal contact. Environmental Science: Processes & Impacts, 2015, 17:667-673. (SCI, IF₂₀₁₅=2.401)
(14) Ruifang Fan*, Dongli Wang, Jianwen She. Method development for the simultaneous analysis of trans, trans-muconic acid, 1, 2-dihydroxybenzene, S-phenylmercapturic acid and S-benzylmercapturic acid in human urine by liquid chromatography/tandem mass spectrometery. Analytical Methods, 2015, 7: 573-580. (SCI, IF₂₀₁₅=1.821)
(15) Junnan Li, Ruifang Fan*, Shaoyou Lu*, Dongru Zhang，Yuanxiu Zhou, Yanshan Lv. Exposure to Polycyclic Aromatic Hydrocarbon could cause their oxidative DNA Damage: A Case Study for College Students in Guangzhou, China. Environmental Science and Pollution Research, 2015, 22: 1770-1777. (SCI, IF₂₀₁₅=2.828)

国家发明专利一项：
范瑞芳，液相色谱串联质谱分析尿液中苯和甲苯四种代谢产物的方法，授权专利号：ZL-0.3，授权日期：2014年4月2日。