郭玲 生物医药研究院 研究副教授 guol@sustc.edu.cn



教育经历
2005.9-2010.7 南方医科大学，医学博士
2000.9-2005.7 济宁医学院，医学学士


工作经历
2014.9-至今 南方科技大学 历经高级研究****、研究助理教授、研究副教授
2013.11-2014.9 清华大学深圳研究生院 讲师
2010.9-2013.11 清华大学 博士后


交叉研究领域
三维微环境构建及其调控干细胞和组织再生的机制研究


代表文章
1.Guo L, Cai T, Chen K, Wang R, Wang J, Cui C, Yuan J, Zhang K, Liu Z, Deng Y, Xiao G, Wu C. Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ. Journal of Cell Biology. 2018Apr 2;217(4):1431-1451.（该文章被Nature reviews cell and molecular biology发文介绍其成果）.
2.Guo L, Zhou Y, Wang S and Wu Y. Epigenetic changes of mesenchymal stem cells in 3D spheroids. Journal of Cellular and Molecular Medicine. 2014 Oct;18(10):2009-19. (引用38次).
3.Guo L, Ge JF, Zhou Y, Wang S and Wu Y. 3D Spheroid Cultured Mesenchymal Stem Cells Devoid of Embolism Attenuate Brain Injury after Stroke. Stem Cells and Development. 2014 May 1;23(9):978-89. (引用27次).
4.Guo L, Ge J, Wang S, et al. A novel method for efficient delivery of stem cells to the ischemic brain [J]. Stem cell research & therapy, 2013, 4(5): 116. (引用15次).
5.Guo L, Zhao RC, Wu Y. The role of miRNAs in self-renewal and differentiation of mesenchymal stem cells. Exp Hematol. 2011 Jun; 39 (6):608-16.（封面文章，引用130次）。
6.Guo L, Huang ZX, Chen XW, Deng QK, Yan W, Zhou MJ, Ou CS, Ding ZH. Differential expression profiles of microRNAs in NIH3T3 cells in response to UVB irradiation. Photochem Photobiol. 2009; 85(3):765-773. （引用82次）。
7.Ge J*, Guo L*, Wang S, et al. The Size of Mesenchymal Stem Cells is a Significant Cause of Vascular Obstructions and Stroke [J]. Stem Cell Reviews and Reports, Stem Cell Rev. 2014 Apr;10(2):295-303. （共同第一, 引用66次）。
8.Wang X, Wang J, Guo L, Wang X1, Chen H, Wang X, Liu J, Tredget EE, Wu Y. Self-assembling peptide hydrogel scaffolds support stem cell-based hair follicle regeneration. Nanomedicine. 2016 Jun 9. pii: S1549-9634(16)30068-5.
9.Wang S, Guo L, Ge J, Yu L, Cai T, Tian R, Jiang Y, Zhao RCh, Wu Y. Excess Integrins Cause Lung Entrapment of Mesenchymal Stem Cells. Stem Cells. 2015 Nov; 33(11):3315-26.
10.Song P, Xie Z, Guo L, Wang C, Xie W, Wu Y. Human genome-specific real-time PCR method for sensitive detection and reproducible quantitation of human cells in mice. Stem Cell Rev Rep. 2012; 8(4):1155-62.
11.Han B, Li J, Guo L, Wang S, Liu P and Wu Y. Trichostatin A stabilizes the expression of pluripotent genes in human mesenchymal stem cells during ex vivo expansion. PLoS ONE. 2013 Nov 27;8(11): e81781.
12.Wang X, Wang X, Liu J, Cai T, Guo L, Wang S, Wang J, Cao Y, Ge J, Jiang Y, Tredget EE, Cao M, Wu Y. Hair Follicle and Sebaceous Gland De Novo regeneration with Cultured pidermal Stem Cells and Skin-Derived Precursors. Stem Cells Transl Med. 2016 Dec;5(12):1695-1706.
13.Zhou M, Liu W, Ma S, Cao H, Peng X, Guo L, Zhou X, Zheng L, Guo L, Wan M, Shi W, He Y, Lu C, Jiang L, Ou C, Guo Y, Ding Z. A novel onco-miR-365 induces cutaneous squamous cell carcinoma. Carcinogenesis. 2013; 34(7):1653-9.
14.Li Z, Liu C, Xie Z, Song P, Zhao RC, Guo L, Liu Z, Wu Y. Epigenetic dysregulation in mesenchymal stem cell aging and spontaneous differentiation. PLoS One. 2011; 6(6): e20526.


联系方式
guol@sustech.edu.cn