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广州医科大学生物化学与分子生物学导师教师师资介绍简介-秦宝明

本站小编 Free考研考试/2021-05-31



秦宝明, 男,研究员,博士生导师,1975年生
简历:
1994.9-1998.6,北京大学生命科学学院生物化学与分子生物学学士
2007.9-2010.6,中国科学院广州生物医药与健康研究院细胞生物学博士
2004.9-2007.8,中科院广州生物医药与健康研究院 助理研究员
2010.7-2013.8,中科院广州生物医药与健康研究院副研究员
2013.9-现在,中科院广州生物医药与健康研究院研究员
研究领域:
代谢和细胞命运:
1-干细胞的代谢如何调节?
2-自噬如何维持干细胞稳态?
3-表观遗传学如何整合到代谢调节中?
获奖及荣誉
2010年,中国科学院“院长优秀奖”、“优秀毕业生”
2011年,中国科学院“优秀博士学位论文”
2013年,“国家自然科学奖”二等奖
2016年,“国家重点研发计划-干细胞及转化研究专项”首席科学家
代表论著
1-Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zhang M, Liu L, Xu Y, Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA, Qin B#, Pei D#. (2015) Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming. Nature Cell Biology, 17: 715-725.
2-Su J, Pei D, Qin B#. (2013) Roles of small molecules in somatic cell reprogramming. Acta Pharmacologica Sinica 34:719–24.
3-Bao X, Zhu X, Liao B, Benda C, Zhuang Q, Pei D, Qin B#, Esteban MA#. (2013) MicroRNAs in somatic cell reprogramming. Current Opinion in Cell Biology 25(2):208-14.
4-Esteban MA*, Wang T*, Qin B*, Yang J, Qin D, Cai J, Li W, Weng Z, Chen J, Ni S, Chen K, Li Y, Liu X, Xu J, Zhang S, Li F, He W, Labuda K, Song Y, Peterbauer A, Wolbank S, Redl H, Zhong M, Cai D, Zeng L, Pei D. (2010) Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 6:1–9. (Cover story)
5-Qin B, He M, Chen X, Pei D. (2006) Sorting Nexin 10 induces giant vacuoles in mammalian cells. Journal of Biological Chemistry 281 (48): 36891-6. (Cover story)
6-Qin B, Chen X, Zhu J, Pei D. (2005) Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy. Cell Research 15 (3): 212-7.
7-Cui P*, Qin B*, Liu N, Pan G, Pei D. (2004) Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. Experimental Cell Research 293: 154-63.
8-Li L, Zhang Q, Yang H, Zou Q, Lai C, Jiang F, Zhao P, Luo Z, Yang J, Chen Q, Wang Y, Newsome PN, Li W, Chen S, Wang D, Siu TS, Tam S, Tse HF, Qin B, Bao X, Esteban MA, Lai L. (2017) Fumarylacetoacetate hydrolase knock-out rabbit model for hereditary tyrosinemia type 1. Journal of Biological Chemistry 292:4755–4763.
9-Yang J, Wang Y, Zhou T, Wong LY, Tian XY, Hong X, Lai WH, Au KW, Wei R, Liu Y, Chen LH, Liang G, Huang Z, Fan W, Zhao P, Wang X, Ibanez DP, Luo Z, Li Y, Zhong X, Chen S, Wang D, Li L, Lai L, Qin B, Bao X, Hutchins AP, Siu CW, Huang Y, Esteban MA, Tse HF. (2017) Generation of human liver chimeric mice with hepatocytes from familial hypercholesterolemia induced pluripotent stem cells. Stem Cell Reports 8:605–618.
10-Xu Y, Zhang M, Li W, Zhu X, Bao X, Qin B, Hutchins AP, Esteban MA. (2016) Transcriptional control of somatic cell reprogramming. Trends in Cell Biology 26:272–288.


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