郑辉性别:
男
职务:
职称:
研究员
学历:
博士通讯地址:
广州市开源大道190号
电话:
邮政编码:
510530
传真:
电子邮件:
zheng_hui@gibh.ac.cn
简历：
研究领域：
1。神经干细胞与学习和记忆
社会任职：
获奖及荣誉：
代表论著：
1.Zheng,H.,Chu,J.,Qiu,Y.,Loh,H.H.andLaw,P.Y.(2008a)Agonist-selectivesignalingisdeterminedbythereceptorlocationwithinthemembranedomains.ProcNatlAcadSciUSA,105,9421-9426.
2.Zheng,H.,Chu,J.,Zeng,Y.,Loh,H.H.andLaw,P.Y.(2010a)YinYang1phosphorylationcontributestothedifferentialeffectsofmu-opioidreceptoragonistsonmicroRNA-190expression.JBiolChem,285,21994-22002.
3.Zheng,H.,Loh,H.H.andLaw,P.Y.(2008b){beta}-Arrestin-Dependent{micro}-OpioidReceptor-ActivatedExtracellularSignal-RegulatedKinases(ERKs)TranslocatetoNucleusinContrasttoGProtein-DependentERKActivation.MolPharmacol,73,178-190.
4.Zheng,H.,Loh,H.H.andLaw,P.Y.(2010b)Agonist-selectivesignalingofGprotein-coupledreceptor:Mechanismsandimplications.IUBMBLife,62,112-119.
5.Zheng,H.,Zeng,Y.,Chu,J.,Kam,A.Y.,Loh,H.H.andLaw,P.Y.(2010c)ModulationsofNeuroDactivitycontributetothedifferentialeffectsofmorphineandfentanylondendriticspinestability.JNeurosci,30,8102-8110.
6.Zheng,H.,Zeng,Y.,Zhang,X.,Chu,J.,Loh,H.H.andLaw,P.Y.(2010d){micro}-OpioidReceptorAgonistsDifferentiallyRegulatetheExpressionofmiR-190andNeuroD.MolPharmacol,77,102-109.
7.Chu,J.,Zheng,H.,Loh,H.H.andLaw,P.Y.(2008)Morphine-inducedmu-opioidreceptorrapiddesensitizationisindependentofreceptorphosphorylationandbeta-arrestins.CellSignal,20,1616-1624.
8.Chu,J.,Zheng,H.,Zhang,Y.,Loh,H.H.andLaw,P.Y.(2010)Agonist-dependentmu-opioidreceptorsignalingcanleadtoheterologousdesensitization.CellSignal,22,684-696.
9。Pan,G.,Li,J.,Zhou,Y.,Zheng,H.andPei,D.(2006)Anegativefeedbackloopoftranscriptionfactorsthatcontrolsstemcellpluripotencyandself-renewal.FasebJ,20,1730-1732.
