蔡倩性别:
男
职务:
职称:
研究员
学历:
博士通讯地址:
广州萝岗区科学城开源大道190号
电话:
邮政编码:
510530
传真:
电子邮件:
cai_qian@gibh.ac.cn
简历：
2001-2006中国科学院上海有机化学研究所博士
2006-2009美国密歇根大学博士后
2009-中国科学院广州生物医药与健康研究院
研究领域：
1、药物合成工艺和有机化学研究
2、基于结构基础合理设计合成小分子化合物做为抗肿瘤以及其它疾病药物，例如蛋白质激酶小分子抑制剂，聚糖蛋白质小分子抑制剂等。
社会任职：
获奖及荣誉：
代表论著：
1.Cai,Qian;Sun,Haiying;Peng,Yuefeng,Lu,Jianfeng;Nikolovaks-Coleska,Zaneta;McEachern,Donna;Liu,Liu;Qiu,Su;Yang,Chao-Yie;Miller,Rebecca;Yi,Han;Zhang,Tao;Sun,Duxin;Kang,Sanmao;Guo,Ming;Leopold,Lance;Yang,Dajun;Wang,Shaomeng.APotentandOrallyActiveAngagonist(SM-406/AT-406)ofMultipleInhibitorofApoptosisProteins(IAPs)inClinicalDevelopmentforCancerTreatment.J.Med.Chem.2011,dx.doi.org/10.1021/jm101505d.
2.Cai，Qian；Zhou,Fengtao;Xu,Tianfeng;Fu,Liangbing;Ding,Ke.Copper-CatalyzedTandemReactionsof1-(2-Iodoary)-2-yn-1-oneswithIsocyanidesfortheSynthesisof4-Oxo-indeno[1,2-b]pyrroles.Org.Lett.2011,13,340.
3.Cai,Qian;Li,Zhengqiu;Wei,Jiajia;Fu,Liangbin;Ha,Chengyong;Pei,Duanqing;Ding,Ke.SynthesisofAza-FusedPolycyclicQuinolinesthroughCopper-CatalyzedCascadeReactionsOrg.Lett.2010,12,1500.
4.Cai,Qian;Li,Zhengqiu;Wei,Jiajia;Ha,Chengyong;Pei,Duanqing;Ding,Ke.AssemblyofIndole-2-CarboxylicAcidEstersthroughaLigand-FreeCopper-CatalysedCascadeProcess.Chem.Commun.2009，7581.
5.Wang,Deping;Cai,Qian;Ding,Ke.AnEfficientCopper-CatalyzedAminationofArylHalidesbyAqueousAmmonia.Adv.Synth.Catal.2009,351,1722.
6.Cai,Qian;Zhang,Hui;Zou,Benli;Xie,Xiaoan;Zhu,Wei;He,Gang;Wang,Jing;Pan,Xianhua;Chen,Yu;Yuan,Qiliang;Liu,Feng;Lu,Biao;Ma,Dawei.AminoAcid-PromotedUllmann-typeCouplingReactionsandTheirApplicationsinOrganicSynthesis.PureAppl.Chem.,2009,81,227.
7.Ma,Dawei;Cai,Qian.Copper/AminoAcidCatalyzedCross-CouplingsofArylandVinylHalideswithNucleophiles.Acc.Chem.Res.2008,41,1450.
8.Sun,Haiying;Nikolovska-Coleska,Zaneta;Yang,Chao-Yie;Qin,Dongguang;Lu,Jianfeng;Qiu,Su;Bai,Longchuan;Peng,Yuefeng;Cai,Qian;Wang,Shaomeng.DesignofSmall-MoleculePeptidicandNonpeptidicSmacMimetics.Acc.Chem.Res.2008,41,1264.
9.Cai,Qian;Zou,Benli;Ma,Dawei.MildUllmann-typebiaryletherformationreactionviaCombinationofortho-substituentandligandeffects.Angew.Chem.Int.Ed.2006,45,1276.
