王波，博士 Wang Bo, Ph.D.
教授， Professor
神经生物学 (Neuroscience)
E-mail：bowang@xmu.edu.cn


简历 (Education and Work experience)
2007-2011年，华中科技大学生物技术专业，学士学位；
2011-2016年，田纳西健康医学中心神经生物学，博士学位；
2017-2019年，圣裘德儿童研究医院，博士后；
2020年，厦门大学生命科学学院，教授。
2007-2011, B.S. Biotechnology, Huazhong University of Science and Technology
2011-2016, PhD. Neuroscience, the University of Tennessee Health Science Center
2017-2019, Postdoc. St. Jude Children’s Research Hospital
2020, Professor, School of Life Sciences, Xiamen University


研究领域 (Research Area)
阐述RNA代谢的细胞和分子机制，以及代谢紊乱如何导致退行性疾病， 比如ALS/FTD/IBM
深入阐释自噬在神经退行性疾病发生过程中所扮演的角色
To elucidate the cellular and molecular mechanisms of RNA metabolism and how the dysfunction of RNA metabolism contributes to degenerative diseases, such as ALS/FTD/IBM
To uncover the role of autophagy in the pathogenesis of neurodegeneration


代表性论文 (Selected Publications)(* Corresponding author)：
1.Wang, B.,Maxwell, B., Joo, J.H., Gwon, Y., Messing, J., Mishra, A., Shaw, T., Ward, A., Quan, H., Sakurada, S.M., et al. (2019). ULK1/2 regulate stress granule disassembly through phosphorylation and activation of VCP. Mol Cell 74, 1-16. (Cover story)
*Highlighted in Williams ER. Turning off cellular stress. Sci Signal 12:eaax9738, 2019.
2.Wang, B.,Joo, JH., Mount, R., Teubner, BJW., Krenzer, A., Ward, AL., Ichhaporia, VP., Elizabeth AJ., Khoriaty, R., Peters ST., et al. (2018). The COPII cargo adapter SEC24C is essential for neuronal homeostasis.J Clin Invest128, 3319–3332.
3.Wang, B.,Iyengar, R., Li-Harms, X., Joo, J.H., Wright, C., Lavado, A., Yang, M., Guan, JL., Green, DR., Cao, X., and Kundu, M. (2017). The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway. Autophagy3, 1-16. (Cover story)
4.Wang, B.& Kundu, M. (2017). Canonical and noncanonical functions of ULK/Atg1. Curr. Opin. Cell Biol. 45, 47-54.
5.Joo, J.H.*, Wang, B.*, Frankel, E., Ge, L., Xu, L., Iyengar, R., Li-Harms, X., Wright, C., Shaw, T.I., Lindsten, T., et al. (2016). The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis. Mol Cell 62, 491-506. *authors contributed equally. (Cover story)
*Highlighted in Zhao YG and Zhang H. The Incredible ULKs: Autophagy and Beyond. Mol Cell63:475-476, 2016.
*Highlighted in Strzyz P. The second job of ULKs. Nat Rev Mol Cell Biol 17:396–397, 2016.
6.Kim, N.C., Tresse, E., Kolaitis, R.M., Molliex, A., Thomas, R.E., Alami, N.H., Wang, B., Joshi, A., Smith, R.B., Ritson, G.P., et al. (2013). VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. Neuron78, 65-80.
7.Xiao, L., Wang, B., Yang, G., and Gauthier, G. (2012). Poly(Lactic Acid)-Based Biomaterials: Synthesis, Modification and Applications, Biomedical Science, Engineering and Technology, Dhanjoo N. Ghista (Ed.), ISBN: 978-953-307-471-9.