崔勇 CUI Yong, Ph.D.
教授 博士生导师
植物细胞生物学 (Plant Cell Biology)
课题组组长
E-mail：cuiyong@xmu.edu.cn
2009年，武汉大学，生物学学士
2011年，香港中文大学，生物学硕士
2014年，香港中文大学，生物学博士
2014-2020年，香港中文大学生命科学学院，博士后
2020年至今，厦门大学生命科学学院，教授、博士生导师
2009, B.Sc., Wuhan University
2011, M.Phil., The Chinese University of Hong Kong
2014, Ph.D., The Chinese University of Hong Kong
2014-2020, Postdoctoral Fellow, School of Life Sciences, The Chinese University of Hong Kong
2020-present, Professor, School of Life Sciences, Xiamen University
研究领域(Research Area)
本课题组主要围绕植物内膜系统针对细胞器的生物发生及囊泡运输的分子机制开展研究。所有植物细胞都含有一套由多种细胞器组成的内膜系统，包括内质网、高尔基体、反式高尔基体网络、多囊泡体、自噬体和液泡等。这些细胞器在植物体各类信号有序调控下，准确而高效地产生，参与细胞内物质运输，对维持植物体生长发育和完成环境应答有着重要的生物学意义。本课题组应用植物细胞生物学、遗传学和生物化学等方法并结合前沿的3D电子断层扫描技术，探索发掘植物体生理及应激状态下，调控细胞器的生成及囊泡运输过程中的关键分子，为改良农作物抗逆提供新思路。
Our research interests are organelle biogenesis and vesicle trafficking in plants. All plant cells contain an endomembrane system with functionally distinct membrane-bound organelles, including the endoplasmic reticulum (ER), Golgi apparatus, trans-Golgi network (TGN), multivesicular body (MVB), autophagosome and vacuole. These organelles are generated accurately and efficiently in a well-organized way so as to exert their essential functions in protein transport, plant growth and responses to the environment. In our study, we use plant cell biological, genetic, biochemical approaches in combination with 3D electron tomography technique to investigate key genes that regulate organelle biogenesis and vesicle trafficking under developmental and stressful conditions in plants, in the hope of providing novel insights for stress resistance in agriculture.
代表性论文(Selected Publications)
1. Cui, Y.*, Zhao, Q., Hu, S., and Jiang, L.* (2020). Vacuole biogenesis in plants: how many vacuoles, how many models?Trends in Plant Science, 25, 538-548.
2. Cui, Y.*, Gao, J., He, Y., and Jiang, L.* (2020). Plant extracellular vesicles.Protoplasma, 257, 3-12.
3. Cui, Y.*, Cao, W., He, Y., Zhao, Q., Wakazaki, M., Zhuang, X., Gao, J., Zeng, Y., Gao, C., Ding, Y., Wong, H.Y., Wong, W.S., Lam, H.K., Wang, P., Ueda, T., Rojas-Pierce, M., Toyooka, K., Kang, B.-H., and Jiang, L*. (2019). A whole-cell electron tomography model of vacuole biogenesis in Arabidopsis root cells.Nature Plants,5, 95-105.
4. Zhao, Q.¹, Shen, J.¹, Gao, C.¹,Cui, Y.¹, Wang, Y., Cui, J., Cheng, L., Cao, W., Zhu, Y., Huang, S., Zhou, Q., Leong, C.K., Leung, P., Chen, X., and Jiang, L.* (2019). RST1 is a FREE1 suppressor that negatively regulates vacuolar trafficking in Arabidopsis.Plant Cell,31, 2152-2168. (1Co-first Authors).
5. Cui, Y.*, Zhuang, X.*, Shen, J.*, Gao, C.*, and Jiang, L.* (2019). Organelle biogenesis and function in plants. SCIENTIA SINICA Vitae,49, 1679–1694.
6. Cui, Y.*, He, Y., Cao, W., Gao, J., and Jiang, L.* (2018). The multivesicular body and autophagosome pathways in plants.Frontiers in Plant Science, 9, 1837.
7. Cui, Y., Zhao, Q., Xie, H.T., Wong, W.S., Wang, X., Gao, C., Ding, Y., Tan, Y., Ueda, T., Zhang, Y., and Jiang, L.* (2017). MONENSIN SENSITIVITY1 (MON1)/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-mediated Rab7 activation regulates tapetal programmed cell death and pollen development in Arabidopsis.Plant Physiology, 173, 206-218.
8. Zhuang, X.¹, Chung, K.P.¹,Cui, Y.¹, Lin, W., Gao, C., Kang, B.H., Jiang, L.* (2017). ATG9 regulates autophagosome progression from the endoplasmic reticulum in Arabidopsis. Proc. Natl. Acad.Proc. Natl. Acad. Sci. USA 114, E426-E435. (1Co-first Authors).
9. Cui, Y., Shen, J., Gao, C., Zhuang, X., Wang, J., and Jiang, L.* (2016). Biogenesis of Plant Prevacuolar Multivesicular Bodies.Molecular Plant, 9, 774-786. (Cover Article).
10. Cui, Y.*, Gao, C., Zhao, Q., and Jiang, L.* (2016). Using fluorescent protein fusions to study protein subcellular localization and dynamics in plant cells.Methods in Molecular Biology, DOI: 10.1007/978-1-4939-6352-2_7.
11. Zhuang, X.¹,Cui, Y.¹, Gao, C., and Jiang, L.* (2015). Endocytic and autophagic pathways crosstalk in plants. Curr. Opin.Current Opinion in Plant Biology, 28, 39-47. (1Co-first Authors).
12. Cui, Y., Zhao, Q., Gao, C., Ding, Y., Zeng, Y., Ueda, T., Nakano, A., and Jiang, L.* (2014). Activation of the Rab7 GTPase by the MON1-CCZ1 Complex Is Essential for PVC-to-Vacuole Trafficking and Plant Growth in Arabidopsis.Plant Cell, 26, 2080-2097.