童梦莎，博士 TONG Mengsha, Ph.D.
特任副研究员
生物信息学 (Bioinformatics)
E-mail：mstong@xmu.edu.cn


简历 (Education and Work experience)


2013年，福建医科大学药学专业，学士学位；
2016年，福建医科大学生物信息专业，硕士学位；
2019年，清华大学生物信息专业，博士学位；
2019年，厦门大学生命科学学院，助理教授；
2021年，厦门大学生命科学学院，特任副研究员。
B.Sc. Pharmacy, Fujian Medical University, 2013
M.Sc. Bioinformatics, Fujian Medical University, 2016
Ph.D. Bioinformatics, Tsinghua University, 2019


研究领域 (Research Area)

?利用生物信息学技术整合分析单细胞转录组学数据，筛选肿瘤预后标志物与药物靶点
?Using bioinformatics technology to identify cancer prognostic markers and drug targets based on single cell-omics data


代表性论文 (Selected Publications)(* Corresponding author)：

1.Tong M^#,Yu C#, Shi J#, Huang W#, Ge S#, Liu M, Song L, Zhan D, Xia X, Liu W, Feng J, Shi W, Ji J, Gao J, Shi T, Zhu W, Ding C, Wang Y, He F*, Shen L*, Li T*, Qin J*.Phosphoproteomics Enables Molecular Subtyping and Nomination of Kinase Candidates for Individual Patients of Diffuse-Type Gastric Cancer. iScience. 2019 Nov 6;22:44-57. doi: 10.1016/j.isci.2019.11.003.
2.Tong M^#, Yu C#, Zhan D, Zhang M, Zhen B, Zhu W, Wang Y, Wu C, He F*, Qin J*, Li T* Molecular subtyping of cancer and nomination of kinase candidates for inhibition with phosphoproteomics: reanalysis of CPTAC ovarian cancer. EBioMedicine. 2019 Feb;40:305-317. doi: 10.1016/j.ebiom.2018.12.039
3.Tong M^#, Zheng W#, Li H, Li X, Ao L, Shen Y, Liang Q, Li J, Hong G, Yan H, Cai H, Li M, Guan Q, Guo Z.*. Multi-omics landscapes of colorectal cancer subtypes discriminated by an individualized prognostic signature for 5-fluorouracil- based chemotherapy. Oncogenesis.2016 Jul 18;5(7):e242. doi: 10.1038/onc sis.2016.51.
4.Tong M, Zheng W, Lu X, Ao L, Li X, Guan Q, Cai H, Li M, Yan H, Guo Y, Chi P, Guo Z* Identifying clinically relevant drug resistance genes in drug-induced resistant cancer cell lines and post-chemotherapy tissues. Oncotarget2015 Dec 1;6(38):41216-27. doi: 10.18632/ oncotarget.5649.
5.Shen Y#,Tong M^#, Liang Q, Guo Y, Sun HQ, Zheng W, Ao L, Guo Z*, She F*. Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells. The pharmacogenomics journal 2018 Jan;18 (1):23-28. doi: 10.1038/tpj.2016.91.