宋彦龄
职称：教授
电话：
Email：ylsong@xmu.edu.cn
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:: 个人简历
厦门大学化学系化学生物学专业 理学学士 （2006.9–2010.6）
厦门大学化学系化学生物学专业 理学博士 （2010.9–2016.6）
福州大学生物科学与工程学院 助理研究员 （2016.9–2018.1）
上海交通大学分子医学研究院 特任副研究员/副研究员（2018.2–2019.10）
厦门大学化学系 副教授、特任研究员 （2019.11–）

:: 工作方向
复杂体系生物标志物分离分析新方法及新器件 1. 分子定向进化
2. 微纳界面组装及识别机制
液体活检与单细胞分析

:: 承担的基金
1. 国家自然科学基金面上项目（**）：基于可控组装微纳界面的循环肿瘤细胞多维度分型富集及临床应用，2019-2022，主持
2、国家重点研发计划（2018YFC**）：新型生物识别材料库的构建及其制备关键技术研究，2018-2021，子课题负责人
3、国家自然科学基金青年项目（**）：肿瘤外泌体标志物核酸适体的筛选及其在液态活检中的应用，2018-2020，主持

:: 代表性文章
1、 Jialu Zhang, Bingqian Lin, Lingling Wu, Mengjiao Huang, Xingrui Li, Huimin Zhang, Jia Song, Wei Wang, Gang Zhao,*Yanling Song,* and Chaoyong Yang*, DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells,Angew. Chem. Int. Ed.2020,DOI: 10.1002/anie.
2、 Wu L.L.;^#Ding H.M.;^#Qu X.;^#Shi X.A.; Yang J.M.; Huang M.J.; Zhang J.L.; Zhang H.M.; Song J.; Zhu L.;Y.L. Song*, Ma Y.Q.*, Yang C.Y.*, Fluidic Multivalent Membrane Nanointerface Enables Synergetic Enrichment of Circulating Tumor Cells with High Efficiency and Viability, J. Am. Chem. Soc. J. 2020, 142(10), 4800
3、 Huang M.J.; Yang J.J.; Wang T.; Song J.; Xia J.L.; Wu L.L.; Wang W.; Wu Q.Y.; Zhu Z.;Song Y.L.*, Yang C.Y.*, Homogeneous, Low-volume, Efficient and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction. Angew. Chem. Int. Ed. 2020, 59(12), 4800
4、Zheng Y.; Zhang J. L.; Huang M. J.; Wang T.; Qu X.; Wu L. l.; Song J.; Wang W.;Y.L. Song*; Yang C.Y., Selection of Aptamers Against Vimentin for Isolation and Release of Circulating Tumor Cells Undergoing Epithelial Mesenchymal Transition, Anal. Chem. 2020, 92(7), 5178
5、Song, Y;Shi, Y; Huang, M; Wang, W; Wang, Y; Cheng, J; Lei, Z; Zhu, Z and Yang, C*. Bioinspired Engineering of a Multivalent Aptamer-Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells.Angewandte Chemie International Edition2019, 58 (8), 2236 (Inside Cover)
6、 Song, J; Zheng, Y; Huang, M; Wu, L; Zhu, Z;Song, Y* and Yang, C. A Sequential Multi-dimensional Analysis Algorithm for Aptamer Identification based on Structure Analysis and Machine Learning.Analytical Chemistry2019, doi.org/10.1021/acs.analchem.9b05203
7、 Huang, M; Song, J; Huang, P; Chen, X; Wang, W; Zhu, Z;Song, Y* and Yang, C*. Molecular Crowding Evolution for Enabling Discovery of Enthalpy-Driven Aptamers for Robust Biomedical Applications.Analytical Chemistry2019, 91 (16), 10879
8、 Lin, B^#; An, Y^#; Meng, L; Zhang, H; Song, J; Zhu, Z; Wen Liu; *Song, Y* and Yang, C*. Control of CRISPR-Cas9 with Small Molecule-activated Allosteric Aptamer Regulating sgRNAs.Chemical Communications2019, 55 (81), 12223
9、Song, Y; Lin, B; Tian, T; Xu, X; Wang, W; Ruan, Q; Guo, J; Zhu, Z and Yang, C.* Recent Progress in Microfluidics-Based Biosensing.Analytical Chemistry2019, 91 (1), 388
10、 Gao, M; Guo, J;Song, Y*; Zhu, Z* and Yang, C*. Detection of T4 Polynucleotide Kinase via Allosteric Aptamer Probe Platform,ACS Appl. Mater. Interfaces2017, 9 (44), 38356
11、Song, Y; Tian, T; Shi, Y; Liu, W; Zou, Y, Khajavand, T; Zhu, Z and Yang, C*. Enrichment and Single-Cell Analysis of Circulating Tumor Cells,Chemical Science2017, 8 (3),1736
12、 Tian, T; An, Y; Wu, Y;Song, Y*; Zhu, Z and Yang, C*.Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis,ACS Applied Materials Interfaces2017, 9 (36), 30480
13、Song, Y; An, Y; Liu, W; Hou, W; Li, X; Lin B; Zhu, Z; Ge, S*; Yang, H* and Yang, C*. Centrifugal Micropipette-tip with Pressure Signal Readout for Portable Quantitative Detection of Myoglobin,Chemical Communications2017, 53 (86), 11774
14、Song, Y; Shi, Y; Li, X; Ma, Y; Gao, M; Liu, D, Mao, Y, Zhu, Z and Yang, C*. Afi-Chip: An Equipment-free, Low-cost and Universal Binding Ligand Affinity Evaluation Platform,Analytical Chemistry2016, 88 (16), 8294




:: 获奖情况

:: 学术职务