高锦豪/Jinhao Gao
教授、博士生导师
电话：86-
传真：86-
办公室：卢嘉锡楼528室
电子邮箱：jhgao@xmu.edu.cn
课题组网站： https://jhgao.xmu.edu.cn/
个人简历：

学士（南京大学 2004）
博士（香港科技大学 2008）
博士后（斯坦福大学 2010）
教授（厦门大学 2010.6-）

香港青年科学家奖 (2007)，教育部“新世纪优秀人才支持计划”（2010），福建省“闽江****”****（2011），国家基金委优秀青年科学基金项目资助（2012），福建省****科学基金资助（2012），福建省青年拔尖创新人才（2014），中国化学会青年化学奖（2014），霍英东教育基金会青年教师奖（2016）
研究兴趣：
影像化学生物学；磁共振造影剂；¹⁹F磁共振探针；金属化学生物学；肿瘤诊疗；分子探针
近期主要代表论著：
(1). Luo, X.; Gong, X.; Su, L.; Lin, H.; Yang, Z.; Yan, X.; Gao, J. H.* Activatable Mitochondria-Targeting Organoarsenic Prodrugs for Bioenergetic Cancer Therapy. Angew. Chem. Int. Ed. 2021, 60, 1403-1410.
(2). Lin, H. Y.; Tang, X.; Li, A.; Gao, J. H.* Activatable ¹⁹F MRI Nanoprobes for Visualization of Biological Targets in Living Subjects. Adv. Mater. 2021, 33, **.
(3). Sun, C. J.; Lin, H. Y.; Gong, X. Q.; Yang, Z.; Mo, Y.; Chen, X.; Gao, J. H.* DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators. J. Am. Chem. Soc. 2020, 142, 198-206.
(4). Zhu, X. L.; Tang, X.; Lin, H. Y.; Shi, S.; Xiong, H.; Zhou, Q.; Li, A.; Wang, Q.; Chen, X.; Gao, J. H.* A Fluorinated Ionic Liquid-Based Activatable ¹⁹F MRI Platform Detects Biological Targets. Chem 2020, 6, 1134-1148.
(5). Tang, X.; Gong, X. Q.; Li, A.; Lin, H. Y.; Peng, C.; Zhang, X.; Chen, X.; Gao, J. H.* Cascaded Multiresponsive Self-Assembled ¹⁹F MRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification. Nano Lett. 2020, 20, 363-371.
(6). Zhou, Z.; Yang, L.; Gao, J. H.;* Chen, X.* Structure–Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging. Adv. Mater. 2019, 31, **.
(7). Zhang, Y. J.;* Zhang, L.; Gao, J. H.;* Wen, L. P.* Pro-Death or Pro-Survival: Contrasting Paradigms on Nanomaterial-Induced Autophagy and Exploitations for Cancer Therapy. Acc. Chem. Res. 2019, 52, 3164-3176.
(8). Wei, R.; Gong, X.; Lin, H.; Zhang, K.; Li, A.; Liu, K.; Shan, H.; Chen, X.; Gao, J. H.* Versatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform for Real-Time Visualization of Cargo Delivery. Nano Lett. 2019, 19, 5394-5402.
(9). Li, A.; Tang, X.; Gong, X.; Chen, H.; Lin, H. Y.;* Gao, J. H.* A Fluorinated Bihydrazide Conjugate for Activatable Sensing and Imaging of Hypochlorous Acid by ¹⁹F NMR/MRI. Chem. Commun. 2019, 55, 12455-12458.
(10). Yang, L.; Wang, Z.; Ma, L.; Li, A.; Xin, J.; Wei, R.; Lin, H.; Wang, R.; Chen, Z.; Gao, J. H.* The Roles of Morphology on the Relaxation Rates of Magnetic Nanoparticles. ACS Nano 2018, 12, 4605-4614.
(11). Zhou, Z.; Wu, C.; Liu, H.; Zhu, X.; Zhao, Z.; Wang, L.; Xu, Y.; Ai, H.; Gao, J. H.* Surface and Interfacial Engineering of Iron Oxide Nanoplates for Highly Efficient Magnetic Resonance Angiography. ACS Nano 2015, 9, 3012-3022.
(12). Zhao, Z.; Wang, X.; Zhang, Z.; Zhang, H.; Liu, H.; Zhu, X.; Li, H.; Chi, X.; Yin, Z.; Gao, J. H.* Real-Time Monitoring of Arsenic Trioxide Release and Delivery by Activatable T₁ Imaging. ACS Nano 2015, 9, 2749-2759.
(13). Zhou, Z.; Zhao, Z.; Zhang, H.; Wang, Z.; Chen, X.; Wang, R.; Chen, Z.; Gao, J. H.* Interplay between Longitudinal and Transverse Contrasts in Fe₃O₄ Nanoplates with (111) Exposed Surfaces. ACS Nano 2014, 8, 7976-7985.
(14). Zhao, Z. H.; Zhou, Z. J.; Bao, J. F.; Wang, Z. Y.; Hu, J.; Chi, X. Q.; Ni, K. Y.; Wang, R. F.; Chen, X. Y.; Chen, Z.; Gao, J. H.* Octapod Iron Oxide Nanoparticles as High-Performance T₂ Contrast Agents for Magnetic Resonance Imaging. Nat. Commun. 2013, 4, 2266.
(15). Zhou, Z. J.; Wang, L. R.; Chi, X. Q.; Bao, J. F.; Yang, L. J.; Zhao, W. X.; Chen, Z.; Wang, X. M.; Chen, X. Y.; Gao, J. H.* Engineered Iron-Oxide-Based Nanoparticles as Enhanced T₁ Contrast Agents for Efficient Tumor Imaging. ACS Nano 2013, 7, 3287-3296.
(16). Zhou, Z. J.; Huang, D. T.; Bao, J. F.; Chen, Q. L.; Liu, G.; Chen, Z.; Chen, X. Y.; Gao, J. H.* A Synergistically Enhanced T₁-T₂ Dual-Modal Contrast Agent. Adv. Mater. 2012, 24, 6223-6228.
(17). Gao, J. H.; Gu, H. W.; Xu, B.* Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications. Acc. Chem. Res. 2009, 42, 1097-1107.
(18). Gao, J. H.; Liang, G. L.; Cheung, S. C.; Pan, Y.; Kuang, Y.; Zhao, F.; Zhang, B.; Zhang, X. X.; Wu, E. X.; Xu, B.* Multifunctional Yolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent. J. Am. Chem. Soc. 2008, 130, 11828-11833.
(19). Gao, J. H.; Zhang, W.; Huang, P. B.; Zhang, B.; Zhang, X. X.; Xu, B.* Intracellular Control of Fluorescent Magnetic Nanoparticles. J. Am. Chem. Soc. 2008, 130, 3710-3711.
(20). Gao, J. H.; Liang, G. L.; Zhang, B.; Kuang, Y.; Zhang, X. X.; Xu, B.* FePt@CoS₂ Yolk-shell Nanocrystals as a Potent Agent to Kill HeLa Cells. J. Am. Chem. Soc. 2007, 129, 1428-1433.