俞晓敏，女，教授、硕士生导师。福建省引进高层次B类人才、校****科研人才、代谢组学平台负责人。发表SCI论文16篇，其中第一作者或通讯作者论文9篇。在Journal of Agricultural and Food Chemistry、Plos One、Electronic Journal of Biotechnology、Computational and Structural Biotechnology Journal、Industrial Crops and Products、Plant Cell Reports、ACS Omega和Saudi Journal of Biological Sciences等期刊担任审稿人。



研究兴趣

本课题组的兴趣在于研究微生物源和植物源天然活性产物的合成和调控，研究植物相关微生物群体在植物代谢、抗逆以及生长发育过程中的功能和分子机制。主要研究课题有：
1.微生物群体功能、天然活性产物合成及其与植物的互作
2.茶树的次生代谢及其调控
3.茶叶的风味化学




教育经历
2009.12 – 2014.6：University of Illinois, Urbana-Champaign | 微生物| 博士
2007.08 – 2009.12：University of Illinois, Urbana-Champaign | 微生物| 硕士
2004.09 – 2007.7：福建农林大学| 生物化学与分子生物学| 硕士
2000.09 – 2004.7：福建农林大学| 生物科学| 学士


工作经历
2020.2-至今：教授，海峡联合研究院园艺植物生物学及代谢组学研究中心，福建农林大学
2014.9 –2020.1：副教授，海峡联合研究院园艺植物生物学及代谢组学研究中心，福建农林大学
2015.8 – 2015.9：访问****，Department of Plant Sciences，Weizmann Institute of Science, Israel
2014.11 – 2015.2：访问****，Department of Plant Sciences，Weizmann Institute of Science, Israel
2009.8 – 2010.12：教学助理，School of Molecular and Cellular Biology，University of Illinois，USA
2007.8 – 2014.6：科研助理，Department of Microbiology，University of Illinois，USA


发表论文（#第一作者，*通讯作者)
2020
Yu, X.^#, Xiao, J.^#, Chen, S.^#, Yu, Y., Ma, J., Lin, Y., Li, R., Lin, J., Fu, Z., Zhou, Q., Chao, Q., Chen, L.*, Yang, Z.*, & Liu, R*. (2020). Metabolite signatures of diverse Camellia sinensistea populations. Nature Communications, 11(1), 5586.DOI: 10.1038/s41467-020-19441-1.
Wang, Z.; Zeng, Y.; Wu, X.; Li, Z.; Tao, Y.; Yu, X.; Huang, Z.*; Chen, F.*, Access to chiral a-substituted-b-hydroxy arylphosphonates enabled by biocatalytic dynamicreductive kinetic resolution. Organic & Biomolecular Chemistry2020, 18(14): 2672-2677. DOI: 10.1039/d0ob00379d.
Zhao, X.^#; Chen, S.^#; Wang, S.; Wang, X.; Lin, Y.; Su, F.; Yang, Z.*; Yu, X.*, Defensive responses of tea plants (Camellia sinensis) against tea green leafhopper attack: A multi-omics study. Frontiers in Plant Science 2020, 10 (1705). DOI: 10.3389/fpls.2019.01705.
Chen, S.^#; Liu, H.^#; Zhao, X.; Li, X.; Shan, W.; Wang, X.; Wang, S.; Yu, W.; Yang, Z.*; Yu, X.*, Non-targeted metabolomics analysis reveals dynamic changes of volatile and non-volatile metabolites during oolong tea manufacture. Food Research International2020.DOI: 10.1016/j.foodres.2019.108778.
2019
徐邢燕，陈思，俞晓敏，赵小嫚，林宏政，刘国英，苏峰，高峰，孙云，郝志龙*. 不同烘焙程度与等级武夷肉桂茶品质差异分析. 2019.食品科学.
李鑫磊，俞晓敏，林军，赵小嫚，张妍，林宏政，郝志龙，金心怡*. 基于非靶向代谢组学的白茶与绿茶、乌龙茶和红茶代谢产物特征比较研究. 2019.食品科学.
Li, X.; Smid, S. D.; Lin, J.; Gong, Z.; Chen, S.; You, F.; Zhang, Y.; Hao, Z.; Lin, H.; Yu, X.*; Jin, X.*, Neuroprotective and anti-amyloid β effect and main chemical profiles of white tea: Comparison against green, oolong and black tea. Molecules 2019, 24(10), 1926.DOI: 10.3390/molecules**
2018
Liao, X.; Li, M.; Liu, B.; Yan, M.; Yu, X.; Zi, H.; Liu, R.; Yamamuro, C.*, Interlinked regulatory loops of ABA catabolism and biosynthesis coordinate fruit growth and ripening in woodland strawberry. PNAS 2018, 115, E11542-E11550.
Shan, W.^#; Zhou, Y.^#; Liu, H.; Yu, X.*, Endophytic actinomycetes from tea plants (Camellia sinensis): Isolation, abundance, antimicrobial, and plant-growth-promoting activities. Biomed Research International 2018, **.DOI: 10.1155/2018/**.
Chen, S.^#; Lin, J.^#; Liu, H.; Gong, Z.; Wang, X.; Li, M.; Aharoni, A.; Yang, Z.; Yu, X.*, Insights into tissue-specific specialized metabolism in Tieguanyin tea cultivar by untargeted metabolomics. Molecules2018, 23(7), 1817. DOI: 10.3390/molecules**.
Chen, S.; Li, M.; Zheng, G.; Wang, T.; Lin, J.; Wang, S.; Wang, X.; Chao, Q.; Cao, S.; Yang, Z.; Yu, X.*, Metabolite profiling of 14 Wuyi Rock tea cultivars using UPLC-QTOF MS and UPLC-QqQ MS combined with chemometrics. Molecules2018, 23(2), 104.DOI: 10.3390/molecules**.
2017
Yang, N.; Jiang, J.; Xie, H.; Bai, M.; Xu, Q.; Wang, X.; Yu, X.; Chen, Z.; Guan, Y.*, Metabolomics reveals distinct carbon and nitrogen metabolic responses to magnesium deficiency in leaves and roots of soybean [Glycine max(Linn.) Merr.]. Frontiers in Plant Science 2017, 8(2091).DOI: 10.3389/fpls.2017.02091.
龚智宏，陈思，高江涛，李梅红，汪厦霞，林军，俞晓敏*. 半制备型液相色谱法分离纯化茶叶鲜叶中7种儿茶素类化合物. 2017.色谱. 35(11): 1192-1197.DOI: 10.3724/SP.J.1123.2017.08002.
李瑞姿，林军，汪厦霞，俞晓敏，陈灿理，关跃峰*. 基于不同栽培阶段金线莲的代谢组学分析. 2017. 中国中药杂志. 42(23), 4624-4630.
Shan, W.; Liu, H.; Zhou, Y.; Yu, X.*, Draft genome sequence of Streptomycessp. XY006, an endophyte isolated from tea (Camellia sinensis). Genome Announcements2017, 5, e00971-17.DOI: 10.1128/genomeA.00971-17.
Liu, H.; Shan, W.; Zhou, Y.; Yu, X.*, Draft genome sequence of Paenibacillus sp. XY044, a potential plant growth promoter isolated from a tea plant. 2017. Genome Announcements2017, 5, e01016-17. DOI: 10.1128/genomeA.01016-17.
Zhang, Q.; Cai, M.; Yu, X.; Wang, L.; Guo, C.; Ming, R.; Zhang, J.*, Transcriptome dynamics of Camellia sinensisin response to continuous salinity and drought stress.2017. TreeGenetics & Genomes2017, 13, 78. DOI: 10.1007/s11295-017-1161-9.
2016
Blodgett, J. A.; Zhang, J. K.; Yu, X.; Metcalf, W. W.*, Conserved biosynthetic pathways for phosalacine, bialaphos and newly discovered phosphonic acid natural products. Journal ofAntibiotics2016, 69, 15-25. DOI:10.1038/ja.2015.77.
2015
Huang, T.; Yu, X.; Gelbic, I.; Guan, X.*, RAP-PCR fingerprinting reveals time-dependent expression of development-related genes following differentiation process of Bacillus thuringiensis. CanadianJournal ofMicrobiology2015, 61, 683-90. DOI: 10.1139/cjm-2015-0212.
2014
Yu, X.; Price, N. P.; Evans, B. S.; Metcalf, W. W.*, Purification and characterization of phosphonoglycans from Glycomycessp. strain NRRL B-16210 and Stackebrandtia nassauensisNRRL B-16338. Journal ofBacteriology2014, 196, 1768-79.DOI: 10.1128/JB.00036-14.
Gao, J.; Ju, K. S.; Yu, X.; Velasquez, J. E.; Mukherjee, S.; Lee, J.; Zhao, C.; Evans, B. S.; Doroghazi, J. R.; Metcalf, W. W.; van der Donk, W. A.*, Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster. Angewandte Chemie International Edition2014, 53, 1334-7.DOI: 10.1002/anie..
Cioni, J. P.; Doroghazi, J. R.; Ju, K. S.; Yu, X.; Evans, B. S.; Lee, J.; Metcalf, W. W.*, Cyanohydrin phosphonate natural product from Streptomyces regensis. Journal ofNaturalProduct2014, 77, 243-9.DOI: 10.1021/np400722m.
2013
Yu, X.; Doroghazi, J. R.; Janga, S. C.; Zhang, J. K.; Circello, B.; Griffin, B. M.; Labeda, D. P.; Metcalf, W. W.*, Diversity and abundance of phosphonate biosynthetic genes in nature. PNAS2013, 110, 20759-64.DOI: 10.1073/pnas..
2007
Yu, X.; Huang, T.; Huang, Z.; Powell, C. A.; Guan, X.*, Expression and characterization of inhA gene from Bacillus thuringiensis8010. World Journal of Microbiology and Biotechnology2007, 23, 1621-1625.DOI: 10.1007/s11274-007-9408-5.