研究生导师介绍
姓名：徐晓嵘性 别:男?院 系：第二临床学院
行政职务：专业技术职称：教授导师类别：硕士生导师
从事专业1：生物医学工程从事专业2：从事专业3：
最后学历：博士毕业 最后学位：博士任硕导年月：2012年10月
任博导年月：是否院士：否是否国务院学科评议组成员：否
毕业院校：中国科技大学毕业专业：080401 精密仪器及机械毕业时间：1992年6月
办公电话：E-mail：xu.ronald@hotmail.com是否停招：否
◇ 个人简历：
美国麻省理工学院博士， 斯坦福大学博士后，中科院百人计划，教授，博士生导师。现任重庆医科大学兼职教授， 中国科学技术大学教授，美国俄亥俄州立大学副教授；中国国家自然科学基金委医学部专家评委；美国国家科学基金会(NSF)生物光学组评委；美国科学促进会(AAAS)项目评委； 以及多家杂志的编辑及评审。曾任美国ViOptix 公司的技术总监以及俄州大医学院的兼职教授。主要研究方向包括生物医学光学、医疗器械、多模态医疗影像治疗、多功能载药微纳颗粒以及生物光学仿体的三维打印等。在高影响因子的期刊发表学术论文30余篇，特邀学术报告30余篇，会议论文20余篇，专利十余项。2010年被美国哥伦布CEO杂志评为十大最优秀的俄亥俄人物以及两个科研明星（R&D Superstar）之一。　2011年被授予该年度美国俄亥俄州唯一的年度发明家奖（Inventor of the Year）。
◇ 本人从事的主要研究方向：
医疗仪器， 生物光学，医疗影像导航治疗， 微纳制药， 生物光学仿体的三维打印
◇ ：在国内外核心期刊上发表学术论文情况
论文题目刊物名称刊物国家收录情况卷期排名
Ultrasound-Mediated Destruction of Lhrha-Targeted and Paclitaxel-Loaded Lipid Microbubbles Induces Proliferation Inhibition and Apoptosis in Ovarian Cancer CellsMol Pharm国外EI SCI11 (1)8
A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometryJ Chromatogr B Analyt Technol Biomed Life Sci国外EI SCI9492
Ultrasound-Mediated Destruction of Lhrha-Targeted and Paclitaxel-Loaded Lipid Microbubbles for the Treatment of Intraperitoneal Ovarian Cancer XenograftsMol Pharm国外EI SCI11 (1)8
Co-axial electrospray of microparticles and nanoparticles for biomedical applicationsExpert Review of Medical Devices国外 SCI9（6）1
Targeted microbubbles for ultrasound mediated gene transfection and apoptosis induction in ovarian cancer cells Ultrason Sonochem国外 SCI228
Indocyanine Green loaded microballoons for biliary imaging in cholecystectomyournal of Biomedical Optics国外 SCI17（11）1
Developing digital tissue phantoms for hyperspectral imaging of ischemic woundsBiomed Opt Express国外 SCI31
Multifunctional microbubbles and nanobubbles for photoacoustic imagingContrast Media Mol Imaging国外 SCI111
Drug-loaded biodegradable microspheres for image-guided combinatory epigenetic therapyJournal of Biomedical Optics国外 SCI16（2）1
Ultrasound and photoacoustic dual-modal imaging of thick biological tissue with microbubble enhancementJournal of Biomedical Optics国外 SCI15（1）1
An Automatic Occlusion Device for Remote Control of Tumor Tissue IschemiaTechnology in Cancer Research and Treatment国外 SCI1（9）1
Synthesizing and binding dual-mode poly (lactic-co-glycolic acid) (PLGA) nanobubbles for cancer targeting and imaging Biomaterials国外 SCI1（31）1
Heat-sensitive microbubbles for intraoperative assessment of cancerablation marginsBiomaterials国外 SCI6（31）1
Multifunctional microbubbles for image-guided antivascular endothelial growth factor therapyJournal of Biomedical Optics国外 SCI15（3）1
124I-HuCC49deltaCH2 for TAG-72 antigen-directed positron emission tomography (PET) imaging of LS174T colon adenocarcinoma tumor implants in xenograft mice: Preliminary resultsWorld Journal of Surgical Oncology国外 SCI88
Dual-mode imaging of cutaneous tissue oxygenation and tissue vascular thermal reactivityJournal of Visualized Experiments国外 SCI101
Targeted delivery of microbubbles and nanobubbles for image-guided thermal ablation therapy of tumorsExpert Rev Med Devices国外 SCI7（3）1
Near-Infrared Fluo-rescence Labeled Anti-TAG-72 Monoclonal Antibodies for Tumor Imaging in Colorectal Cancer Xenograft MiceMolecular Pharmaceutics国外 SCI6（2）1
Fabrication of indocyanine green encapsulated biodegradable micro－bubbles for structural and functional imaging of cancerJournal of Biomedical Optics国外 SCI14（3）1
Standardized and reproducible methodology for the comprehensive and systematic assessment of surgical resection margins during breast-conserving surgery for invasive breast cancerBMC Cancer国外 SCI9（1）6
Dynamic schema for near infrared detection of pressure-induced changes in solid tumorsApplied Optics国外 SCI17（16）1
Design and benchtop validation of a handheld integrated dynamic breast imaging system for noninvasive characterization of suspicious breast lesionsTechnology in Cancer Research and Treatment国外 SCI6（7）1
Rapid Thermal Cycling with Low Thermal Inertia Tools Polymer Engineering & Science国外 SCI2（49）1
Optical imaging and spectroscopy for cancer.Expert Rev Med Devices国外 SCI4（1）1
Development of a handheld near infrared imager for dynamic characterization of in vivo biological tissue systemsApplied Optics国外 SCI46（30）1
A prospective pilot clinical trial evaluating the utility of a dynamic near infrared imaging device for characterizing suspicious breast lesions.Breast Cancer Research国外 SCI91
Post-occlusive reactive hyperemia in patients with peripheral vascular diseaseClinical hemorheology and microcirculation国外 SCI1（31）3
The design of conformal cooling channels in injection molding toolingPolymer Engineering & Science国外 SCI41（31）1
Design of an optical probe for surface profile measurementOptical Engineering国外 SCI38（7）2
Fabricating Metal Tooling and Metal Parts by 3D PrintingNaval Research Reviews国外 SCI34
◇ ：出版专著教材情况(注：在书名后注明教材或专著)
名称类别出版单位日期排名
◇ ： 成果获奖情况
成果名称颁奖部门等级完成日期证书号排名
TechColumbus 2010 年度发明家奖校厅其它发明奖*1
Herman Weed教学优秀奖校厅其它其他*1
◇ ：主持重大科研项目情况
项目名称任务来源完成形式完成日期鉴定验收单位主要结论排名
多模态伤口影像的基础问题和标准化研究国家自然科学基金项目2016-12？？？？？？1
Alginate oligomers to treat infectious microbial biofilms其他2013-06？？？？？？1
Hyperspectral imaging of biological tissue其他2012-06？？???1
Ultrasound and fluorescence imaging in cholecystectomy to avoid bile duct injury其他2011-07??????1
Minimally invasive surgery with multimodal imaging guidance其他2011-07??????1
Targeted delivery of temperature-sensitive nanobubbles for intraprocedural assessment of thermal ablation margins in breast cancer其他2010-09??????1
Non-invasive, non-contact, in vivo imaging of tissue metabolism and vascular function其他2009-04??????1
◇ ：目前承担的主要项目
项目名称及下达编号项目类别项目来源起讫时间科研经费(万元)本人承担任务
生物光学仿体的三维打印制备与表征系统国家级国家自然科学基金项目2014-01-01 -2018-12-31 700.00项目负责人
多模态生物医疗影像国家级中央、国家各部门项目2013-01-01 -2015-12-31 100.00项目负责人
多模态伤口影像的基础问题和标准化研究国家自然科学基金项目2013.01-2016.0170.00项目负责人