夏之宁 Title：教授/博导,重庆大学校长助理
E-mail Address：znxia@cqu.edu.cn
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个人/团队介绍 夏之宁，教授/博士生导师，重庆大学校长助理，1995年毕业于丹麦哥本哈根大学，获博士学位。教育部“跨世纪优秀人才”，教育部“高等学校青年教师奖”，国务院政府特殊津贴获得者。中国色谱学会理事，重庆市分析化学学科学术带头人，重庆市色谱学会理事长，重庆市分析测试学会副理事长。《色谱》、《环境化学》等杂志编委。先后主持科技部国际科技合作项目、科技部国家基础研究规划项目（973计划）、国家自然科学基金项目、教育部“高校骨干教师基金”项目以及重庆市重点项目20余项；在SCI收录期刊上发表论文100余篇，出版专著2本，教材3本，获8项专利。主要研究方向包括以下三个方面。1活性天然产物：创新方法筛选中药中的活性成分；改进及应用现代制备技术从中药中获得活性单体成分；活性成分的分子、细胞及动物水平评价。2药物分析化学：手性分离分析方法研究；药物亲和分析；功能化毛细管电泳分析方法的建立及应用。3 微波化学与波谱：微波化学反应的机理、微波热与非热作用、微波在有机化学、分析化学、材料化学中的应用。
学习工作经历
研究领域
项目成果
代表性文章 1. Q.F. Fu, F.Q. Yang, H. Chen,Z.N. Xia, Enhancement of enantioselectivity in chiral capillary electrophoresis using hydroxypropyl-beta-cyclodextrin as chiral selector under molecular crowding conditions induced by dextran or dextrin.Electrophoresis, 2014, 35(20): 2938-2945.
2. F. Li, R. Liu, F.Q. Yang, W. Xiao, C. Chen,Z.N. Xia, Determination of three curcuminoids inCurcuma longaby microemulsionelectrokinetic chromatography with protective effects on the analytes,Analytical Methods, 2014, 6(8): 2566-2571.
3. Q. Gou, L.B. Favero, S.S. Bahamyirou,Z.N. Xia, W. Caminati, Interactions between Carboxylic Acids and Aldehydes: A Rotational Study of HCOOH-CH2O.Journal of Physical Chemistry A, 2014, 118(45): 10738-10741.
4. G. Feng, Q. Gou, L. Evangelisti,Z.N. Xia, W. Caminati, Conformational equilibria in carboxylic acid bimolecules: a rotational study of acrylic acid-formic acid.Physical Chemistry Chemical Physics, 2013, 15(8): 2917-2922.
5. F.Q. Yang, J. Yang, X.M. Zhang, P. Xu,Z.N. Xia, Analysis of volatile components in Curcuma rhizome by microemulsionelectrokinetic chromatography,Journal of Chromatographic Science, 2013, 51(2): 155-160.
6. J. Du,Z.N. Xia, Measurement of the catalytic activity of gold nanoparticles synthesized by a microwave-assisted heating method through time-dependent UV spectra,Analytical Methods, 2013, 5(8): 1991-1995.
7. F. Li, F.Q. Yang,Z.N. Xia, Simultaneous Determination of Ten Nucleosides and Related Compounds by MEEKC with [BMIM]PF6 as Oil Phase,Chromatographia, 2013, 76 (15-16): 1003-1011.
8. Z.N. Xia, Y.X. Lin, L.X. Guo, F.Q. Yang, P. Xu, Y.L. Zhang, J.H. Liu, Development of a cell-based high-throughput peroxisome proliferator-activated receptors (PPARs) screening model and its application for evaluation of the extracts from RhizomaCoptis,Journal of Asian Natural Products Research, 2013, 15(3): 225-234.
9. Z.H. Li, G. Chen, S. Qiao, R.H. Liang, C. Lan,Z.N. Xia, Design and Synthesis of Some New N-Phenylanthranilic Acids from Highly Sterically Hindered Anilines,Synthetic Communications, 2013, 43 (9): 10.
10. H.L. Zuo, F.Q. Yang, W.H. Huang,Z.N. Xia, Preparative gas chromatography and its applications,Journal of Chromatographic Science, 2013, 51(7): 704-715.
11. H.L. Zuo, S.J. Chen, D.L. Zhang, J. Zhao, F.Q. Yang,Z.N. Xia, Quality evaluation of natural Cordycepssinensis from different collecting places in China by the contents of nucleosides and heavy metals,Analytical Methods, 2013, 5(20): 5450-5456.
12. C. Chen, F.Q. Yang, H.L. Zuo, Y.L. Song,Z.N. Xia, W. Xiao, Applications of biochromatography in the screening of bioactive natural products,Journal of Chromatographic Science, 2013, 51(8): 780-790.
13. L.X. Li,Z.N. Xia, F.Q. Yang, H. Chen, Y.L. Zhang, Enantioselective analysis of ofloxacin enantiomers by partial-filling capillary electrophoresis with bacteria as chiral selectors,Journal of Separation Science, 2012, 35(16): 2101-2107.
14. F.Q. Yang, R. Lv, Y.L. Zhang, andZ.N. Xia, Comparison study on nucleosides and nucleotides in edible mushroom species by capillary zone electrophoresis,Analytical Methods, 2012, 4(2): 546-549.
15. L.X. Guo,Z.N. Xia, X. Gao, F. Yin, J.H. Liu, Glucagon-like peptide 1 receptor plays a critical role in geniposide-regulated insulin secretion in INS-1 cells,ActaPharmacologicaSinica, 2012, 33(2): 237-241.
16. J. Du,Z.N. Xia, Interactions of gold nanoparticles and lysozyme by fluorescence quenching method,Analytical Letters, 2012, 45 (15): 2236-2245.
17. P. Xu,Z.N. Xia, Y.X. Lin, Chemical constituents from Edgeworthiagardneri (Thymelaeaceae),Biochemical Systematics and Ecology, 2012, 45: 148-150.
18. Z.T. Chen, Z.B. Zhong,Z.N. Xia, F.Q. Yang, X.J. Mu, Separation of Fluoroquinolones by MEKC Modified with Hydrophobic Ionic Liquid as a Modifier, Chromatographia, 2012, 75 (1-2): 65-70.
19. Z.H. Li, S.Y. Xiao, R.H. Liang,Z.N. Xia, Synthesis of 2-(arylamino)nicotinic acids in high-temperature water,Research on Chemical Intermediates, 2012, 38(7): 1691-1697.
20. H.L. Zuo, F.Q. Yang, X.M. Zhang,Z.N. Xia, Separation of cis- and trans-Asarone from Acorustatarinowii by Preparative Gas Chromatography,Journal of Analytical Methods in Chemistry, 2012, 2012: 402081.
21. X.J. Mu, N.N. Yu, C.S. Wang, X.B. Zou, Z. Abulimite,Z.N. Xia, Evaluation of a new substrate for measurement of serum PON arylesterase activity,Talanta, 2012, 88 :711-716.
22. X.M. Jiang,Z.N. Xia, L.H. Deng, W.L. Wei, J. Chen, J.M. Xu, H.Y. Li, Evaluation of Accuracy for the Measurement of Octanol-Water Partition Coefficient by MEEKC,Chromatographia, 2012, 75 (7-8): 347-352.
23. Y. Wang, F. Li, F.Q. Yang, H.L. Zuo,Z.N. Xia, Simultaneous determination of α-, β- and γ-asarone in Acorustatarinowii by microemulsionelectrokinetic chromatography with [BMIM]PF6 as oil phase,Talanta, 2012, 101: 510-515.
24. G. Feng, L. Evangelisti, L.B. Favero, J.U. Grabow,Z.N. Xia, W. Caminati, On the weak O-H···halogen hydrogen bond: a rotational study of CH3CHClF···H2O.Physical Chemistry Chemical Physics, 2011, 13(31): 14092-14096.
25. F.Q. Yang, H.K. Wang, H. Chen, J.D. Chen,Z.N. Xia, Fractionation of volatile constituents from curcuma rhizome by preparative gas chromatography,Journal of Automated Methods & Management in Chemistry, 2011, 2011:942467.
26. J. Yang,Z.N. Xia, F.Q. Yang, R. Lv, Use of Relative Mobility to Estimate Octanol-Water Partition Coefficients of Drugs by MicroemulsionElectrokinetic Chromatography,ActaChimicaSinica, 2011, 69 (7): 810-814.
27. Z.H. Li,Z.N. Xia, G. Chen, Catalyst-free amination of 2-chloronicotinic acid in water under microwave irradiation,Journal of Chemical Research, 2011, (12): 709-711.
28. K.Y. Shi,Z.N. Xia, T.T. Gan, X.M. Jiang, C. Xia, Applications of real-time monitoring techniques in chemical synthetic ingredients,Spectroscopy and Spectral Analysis, 2010, 30(2): 499-503.
29. G.H. Chen,Z.N. Xia, Y. Lu, Prediction of Cell-Penetrating Peptides Using both Support Vector Machine and Linear Discriminant Analysis,ActaChimicaSinica, 2010, 68(11): 1137-1142.
30.Z.N. Xia, J. Yang, L.X. Li, F.Q. Yang, X.M. Jiang, Determination of Octanol-Water Partition Coefficients by MEEKC Based on Peak-Shift Assay,Chromatographia, 2010, 72 (5-6): 495-501.
31. G.H. Chen,Z.N. Xia, Y. Lu, Three-dimensional vector of pharmacophore atomic interaction and its applications to stereoisomeric description,Chemometrics and Intelligent Laboratory Systems, 2010, 102 (2): 91-99.
32. Y.H. Zhang,Z.N. Xia, L.T. Qin, S.S. Liu, Prediction of blood-brain partitioning: A model based on molecular electronegativity distance vector descriptors,Journal of Molecular Graphics & Modelling, 2010, 29(2): 214-220.
33.Z.N. Xia, T.T. Gan, H. Chen, R. Lv, W.L. Wei, F.Q. Yang, A new open tubular capillary microextraction and sweeping for the analysis of super low concentration of hydrophobic compounds,Journal of Separation Science, 2010, 33(20): 3221-3230.
34. J.H. Jing, G.Z. Liang, H. Mei, S.Y. Xiao,Z.N. Xia, Quantitative structure-mobility relationship studies of dipeptides in capillary zone electrophoresis using three-dimensional holographic vector of atomic interaction field,Molecular Simulation, 2009, (5): 263-269.
35.Z.N. Xia, S. Long, S.Y. Xiao, X.B. Zou, A. D'Aurizio, M. Panunzio, Microwave-Assisted Carbonyl-Carbonyl Coupling Route for the Preparation of a Useful Intermediate in the Synthesis of Carbapenems,Synthetic Communications, 2009, 39 (12): 2151-2160.
36. L.X. Guo, J.H. Liu,Z.N. Xia, Geniposide inhibits COCl2-induced PC12 cells death via the mitochondrial pathway,Chinese Medical Journal, 2009, 122(23): 2886-2892.
37. X.M. Jiang,Z.N. Xia, W.L. Wei, Q. Gou, Direct UV detection of underivatized amino acids using capillary electrophoresis with online sweeping enrichment,Journal of Separation Science, 2009, 32 (11): 1927-1933.
38.Z.N. Xia, L.X. Li, J. Yang, C.Q. Xiong,Investigation of interaction between the drug and cell membrane by capillary electrophoresis,Science in China Series B-Chemistry, 2009, 52 (12): 2200-2204.