教师姓名：钟莉
邮箱地址：jlzhong@cqu.edu.cn
工作电话：未公开
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钟莉?教授(Li/Julia?Zhong，PhD,?MD)，博士生导师?

2009-?迄今?重庆大学生物工程学院教授；重庆市“百人计划”特聘专家

1981-1997华西医科大学（四川大学）临床医学系本科及四川省人民医院

1997-2008英国巴斯大学药理学系博士；国王学院、UEA、巴斯大学任初级、高级博士后；2008-迄今?兼巴斯大学博士副导师

主要研究方向

再生医学及转化医学，皮肤组织修复-光生物学等。皮肤干细胞的运用；新型生物材料：包括微/纳米生物医学及药物靶向输送治疗肿瘤及其药理机制，功能活性蛋白分子的研究。

在读博士研究生：刘永，边春象，Farrukh?Muhammad,?吴燕；硕士研究生4名?

主要基金?国家自然科学基金面上项目；863国家高科技研究计划

主要学术兼职?中国自由基与医学专业委员会委员等

招收学生?热忱欢迎勤奋好学对跨学科研究有浓厚兴趣生物工程、技术或生物学以及临床医学、化学、化工、物理等背景的学生。重大招生目录071000，083121，083123等。与国内外单位建立了良好合作关系并个性化培养学生。联系jlzhong@cqu.edu.cn;?电话：**?

主要研究成果：共发表学术论文30余篇。?其中第一及通讯作者文章共15?篇，IF?累计近40分，他引共130余次。

1.??????Zhong?JL(钟莉)*,?Raval?CM,?Nisar?MF,?Zhang?J,?Tyrrell?R.?Development?of?Refractoriness?of?HO-1?Induction?to?a?Second?Treatment?with?UVA?Radiation?and?the?Involvement?of?Nrf2?in?Human?Skin?Fibroblasts.?Photochemistry?and?photobiology.?Nov?2014;90(6):1340-1348.?

2.??????Nisar?MF,?Parsons?KSG,?Bian?CX,?Julia?Li?Zhong.*?Invited?Review：Induction?of?heme?oxygenase-1?in?skin?fibroblasts?by?UVA:?a?potential?phototherapeutic?strategy?of?scleroderma.?Photobiology?and?photochemistry.?2015,?91:?210–220

3.??????Huang?X,?Wang?X,?Wang?S,?Yang?J,?Zhong?L,?Pan?J.?UV?and?dark-triggered?repetitive?release?and?encapsulation?of?benzophenone-3?from?biocompatible?ZnO?nanoparticles?potential?for?skin?protection.?Nanoscale.?2013?Jun?21;5(12):5596-601.?IF-6.9（JCR?1区)

4.??????Raval?CM,?Zhong?JL,?Mitchell?SA.?Tyrrell?RM.?The?role?of?Bach1?in?ultraviolet?a?mediated?human?heme?oxygenase?1?regulation?in?human?skin?fibroblasts.?Free?Radic?Biol?Med.?2012,?52(1):227-36.?

5.??????Aroun?A^#,?Zhong?JL^#?,?Tyrrell?RM,?Pourzand?C.?Iron,?oxidative?stress?and?the?example?of?solar?ultraviolet?A?radiation.?Photochem?Photobiol?Sci.,?2012,?11(1):118-134.

6.??????Zhong?JL,?Yang?L,?Lü?F,?Xiao?H,?Xu?R,?Wang?L,?Zhu?F,?Zhang?Y.?UVA,?UVB?and?UVC?induce?differential?response?signaling?pathways?converged?on?the?eIF2α?phosphorylation.?Photochemistry?Photobiology,?2011,?87(5):?1092-1104.

7.??????Chiang?MY,?Yangben?Y,?Lin?NJ,?Zhong?JL,?Yang?L.?Relationships?among?cell?morphology,?intrinsic?cell?stiffness?and?cell-substrate?interactions.?Biomaterials.?2013?;34(38):9754-62.

8.??????Xiang?Y,?Liu?G,?Yang?L,?Zhong?JL*.?UVA-induced?protection?of?skin?through?the?induction?of?heme?oxygenase-1.?Review.?BioScience?Trends.?2011,?5(6):239-244.?

9.??????Tian?FF,?Zhang?FF,?Lai?XD,?Wang?LJ,?Yang?L,?Wang?X,?Singh?G,?Zhong?JL*.?Nrf2-mediated?protection?against?UVA?radiation?in?human?skin?keratinocytes.?BioscienceTrend.?2011,?5(1):23-29.?

10.??Zhong?JL,?Raval?C,?Edwards?GP,?Tyrrell?RM.?A?role?of?Bach1?and?HO-2?in?suppression?of?basal?and?UVA-induced?HO-1?expression?in?human?skin?keratinocytes.?Free?Radic?Biol?Medicine,?2010,?48(2):196-206.

11.??Zhong?JL,?Edwards?GP,?Raval?C,?Li?H,?Tyrrell?RM.?The?Role?of?Nrf2?in?Ultraviolet?A?Mediated?Heme?oxygenase?1.?Induction?in?Human?Skin?Fibroblasts.?Photochem.?Photobiol?Sci,?2010,?9(1):18-24.

12.??Zhang?X^#,?Zhong?JL^#,?Sun?LR,?Xun?Li?X,?Ward?SG,?Shi?YQ,?Zhang?XF,?Cheng?YN,?Gao?JJ,?Qu?X.?N(3)-o-toluyl-fluorouracil?inhibits?human?hepatocellular?carcinoma?cell?growth?via?sustained?release?of?5-FU.?Cancer?Chemother?Pharmacol.?2010,?66(1):11-19.?

13.??Sun?LR^#,?Zhong?JL^#,?Cui?SX,?Li?X,?Ward?SG,?Shi?YQ,?Zhang?XF,?Cheng?YN,?Gao?JJ,?Qu?XJ.?Modulation?of?P-glycoprotein?activity?by?substituted?quinoxalinones?compound?QA3?in?adriamycin-?resistant?K562/A02?cells.?Pharmacological?Reports.?2010,?62(2):333-342.

14.??Zhong?JL,?Yiakouvaki?A,?Holley?P,?Tyrrell?RM,?Pourzand?C.?Susceptibility?of?skin?cells?to?UVA-induced?necrotic?cell?death?reflects?the?intracellular?level?of?labile?iron.?J?Invest?Dermatol.?2004,?123(4):771-780.?

15.??Moss?ML,?Powell?G,?Miller?MA,?Bin?Q,?Sang?QX,?De?Strooper?B,?Tesseur?I,?Lichtenthaler?SF,?Taverna?M,?Zhong?JL,?Dingwall?C,?Ferdous?T,?Schlomann?U,?Zhou?P,?Griffith?L,?Lauffenberger?D,?Petrovich?R,?Bartsch?JW.?ADAM9?inhibition?increases?membrane?activity?of?ADAM10?and?controls?²?secretase?processing?of?amyloid?precursor?protein.?J?Biol?Chem,?2011,?286(47):40443-40451.?

16.??Li?L,?Li?H,?Qian?Y,?Li?X,?Singh?GK,?Zhong?L,?Liu?W,?Lv?Y,?Cai?K,?Yang?L.?Electrospun?poly?(-caprolactone)/silk?fibroin?core-sheath?nanofibers?and?their?potential?applications?in?tissue?engineering?and?drug?release.?Int?J?Biological?Macromolecules,?2011,?49(2):223-232.

17.??Li?L,?Qian?Y,?Jiang?C,?Lv?Y,?Liu?W,?Zhong?L,?Cai?K,?Li?S,?Yang?L.?The?use?of?hyaluronan?to?regulate?protein?adsorption?and?cell?infiltrationin?nanofibrous?scaffolds.?Biomaterials.?2012,?33(12):3428-3445.

参加会议、特邀发言及主持会议：

1.??????特邀发言：“The?8th?Pong?Ding?Yuen?Int.?Symposium?on?Traditional?Chinese?Medicine?cum;?The?2nd?International?Chinese?Symposium?on?Free?Radical?Research;?The?6th?Symposium?for?Three?Districts?of?Cross-straits?on?Free?Radical?Research”.?2014.11.14-17?Hong?Kong.

2.??????主持第三届自由基生物学与自由基医学发展战略研讨会2013.11.13－16,云南·腾冲

3.??????特邀发言：第八届全国光生物学学术会议2013.11.11－14,云南·腾冲

4.??????发言获奖“SM1-017,?Development?of?refractoriness?of?HO-1?induction?to?a?second?treatment?with?UVA?radiation?and?the?involvement?of?Nrf2.?Winner?of?the?Young?Investigator?Travel?Award?of?4th?international?symposium?on?natural?antioxidants.?A?satellite?meeting?of?The?17th?IUPAB?International?Biophysics?Congress?(17th?IBC).中国北京国家会议中心.?2011.10.

5.??????主持分会Optics?in?health?care?and?biomedical?Optics?IV:?Optical?techniques:?Advance?in?research?9A.?Photonics?Asia?2010?(2010亚洲光电子会议)?中国北京国家会议中心.2010.10.18-21.

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