组长：孟颂东 研究员
研究方向
乙肝病毒、宿主因子、细胞免疫研究

研究队伍
课题组长：孟颂东　研究员 博士生导师
电子邮件：mengsd@im.ac.cn
通讯地址：北京市朝阳区北辰西路1号院3号，中国科学院微生物研究所
邮编：100101

组员
陈立钊，博士，助理研究员
胡　坤，博士，助理研究员


研究生
范红霞　2009-2012
邱立鹏　2007-2010
王赛锋　2008-2011
李星辉　2007-2012
任玉林　2007-2010
张　宇　2007-2012
王彦中　2008-2011
李　鑫　2008-2011
闫晓丽　2008-2011
赵　报　2008-2011
郝军利　2009-2012


博士后
张小俊
李长菲


主要履历及经历
1987 -1991 新疆大学生物系 学士
1991 -1994 中科院新疆生态与地理所 硕士
1995 -1998 中科院沈阳应用生态所 博士
1998 -2001 中科院微生物所分子病毒与免疫中心，博士后
2002 -2007 美国西南医学中心肿瘤免疫中心，博士后，后转成Instructor
2007 -迄今，中科院微生物所病原微生物与免疫院重点实验室研究员、博士生导师

发表论文
1
Zhen Liu, Xinghui Li, Lipeng Qiu, Xiaojun Zhang, Lizhao Chen, Sheng Cao, Fusheng Wang, Songdong Meng. 2009. Treg suppress CTL responses upon immunization with HSP gp96. European Journal of Immunology, 39:1-11
2
Sheng Cao, Yang Li，Jin Li, Changfei Li, Zhang Wei, Zhengqi Yang, Songdong Meng. 2009. Quantitative determination of HER2 expression by confocal microscopy assay in CTCs of breast cancer. Oncology Reports (accepted)
3
Songdong Meng, Debu Tripathy, Sanjay Shete, Raheela Ashfaq, Hossein Saboorian, Barbara Haley, Eugene Frenkel, David Euhus, Marilyn Leitch, Cynthia Osborne, Edward Clifford, Steve Perkins, Peter Beitsch, Amanullah Khan, Larry Morrison, Dorothee Herlyn, Leon WMM Terstappen, Nancy Lane, Jianqiang Wang, and Jonathan Uhr. 2006. uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues. Proceedings of the National Academy of Sciences of the United States of America，103(46): 17361-17365.
4
Fehm T, Solomayer EF, Meng S, Tucker T, Lane N, Wang J, Gebauer G. 2005. Methods of isolating circulating epithelial cells and criteria for their classification as carcinoma cells. Cytotherapy, 7(2):171-185
5
Songdong Meng, Debasish Tripathy, Eugene P Frenkel, Sanjay Shete, Elizabeth Z Naftalis, James F Huth, Peter D Beitsch, Marilyn Leitch, Susan Hoover, David Euhus, Barbara Haley, Larry Morrison, Timothy P Fleming, Dorothee Herylyn, Leon WMM Terstappen, Tanja Fehm, Thomas F Tucker, Nancy Lane, Jianqiang Wang, Jonathan W Uhr. 2004. Circulating tumor cells in patients with breast cancer dormancy. Clinical Cancer Research, 10(24):8152-8162.
6
Meng S, Tripathy D, Shete S, Ashfaq R, Haley B, Perkins S, Beitsch P, Khan A, Euhus D, Osborne C, Frenkel E, Hoover S, Leitch M, Clifford E, Vitetta E, Morrison L, Herlyn D, Terstappen LW, Fleming T, Fehm T, Tucker T, Lane N, Wang J, Uhr J. 2004. HER-2 gene amplification can be acquired as breast cancer progresses. Proceedings of the National Academy of Sciences of the United States of America, 101(25):9393-9398.
7
李燕，孟颂东，陈溥言,高福,田波.马立克氏病毒感染的鸡肝脏肿瘤中热应激蛋白108含量的增高及其基因序列分析和表达的研究. 自然科学进展 , 13(7): 698-702, 2003
8
Fehm T, Sagalowsky A, Clifford E, Beitsch P, Saboorian H, Euhus D, Meng S, Morrison L, Tucker T, Lane N, Ghadimi BM, Heselmeyer-Haddad K, Ried T, Rao C, Uhr J. 2002. Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant. Clinical Cancer Research. 8(7): 2073-2084
9
Meng S, Song J, Rao Z, Tien P, Gao G. 2002. Three-step purification of gp96 from human liver tumor tissues suitable for isolation of gp96-bound peptides. Journal of Immunological Methods, 264(1-2): 29-35.
10
Huang GC, Meng SD, Wang R, Yang HY, Tian B. 2002. Cloning of glutamate dehydrogenase cDNA from Chlorella sorokiniana and analysis of transgenic tobacco plants. Acta Botanic Sinica, 44(3): 318-324.
11
Songdong Meng, Tong Gao, George F. Gao, Po Tien. 2001. HBV-specific peptide associated with heat shock protein gp96. Lancet, 357(17): 528-529