胡莉娟,
沈沁浩,
陈章悦,
周家豪,
热法提,
吴奕帆,
王成聪,
费承鑫^,,
李华玲^,
扬州大学医学院, 扬州 225009

作者简介: 胡莉娟(1996-),女,本科生,研究方向为纳米材料生物毒性,E-mail:1226594560@qq.com.

通讯作者: 费承鑫,1083803086@qq.com ; 李华玲,2274292599@qq.com

基金项目: 国家自然科学基金项目(81671056)；江苏省高校基金项目(18KJA320014)


中图分类号: R73-34

Toxicity of Magnetic Nanoparticles to Different Model Organisms

Hu Lijuan,
Shen Qinhao,
Chen Zhangyue,
Zhou Jiahao,
Re Fati,
Wu Yifan,
Wang Chengcong,
Fei Chengxin^,,
Li Hualing^,
Medical College, Yangzhou University, Yangzhou 225009, China

Corresponding authors: Fei Chengxin,1083803086@qq.com ; Li Hualing,2274292599@qq.com

CLC number: R73-34

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摘要:磁性纳米颗粒在生物医学等领域应用广泛，而其毒性研究尚未深入，对生物的影响及作用机制仍未阐明。本文综述了磁性纳米颗粒近年来对于细胞、鼠、家兔和秀丽隐杆线虫的毒理学研究，为磁性纳米颗粒的应用提供参考。
关键词: 磁性纳米颗粒/
秀丽隐杆线虫/
细胞/
鼠/
家兔/
毒性

Abstract:Magnetic nanoparticles (MNPs) have been widely used in biomedical science and other fields. However, little research has been done on their toxicity. The biological effects and mechanisms of MNPs on organisms are still unknown. This review summarizes the toxicological researchs of MNPs on cells, mice, rabbits and Caenorhabditis elegans in recent years, providing a reference for the application of MNPs.
Key words:magnetic nanoparticles (MNPs)/
Caenorhabditis elegans/
cell/
mice/
rabbit/
toxicity.