林必桂^1,2,3,
于云江^1,2,3,
陈希超²,
李良忠²,
乔静⁴,
马瑞雪²,
向明灯²
1. 有机地球化学国家重点实验室, 中国科学院广州地球化学研究所, 广州 510640;
2. 国家环境保护环境污染健康风险评价重点实验室, 环境保护部华南环境科学研究所, 广州 510655;
3. 中国科学院大学, 北京 100049;
4. 清远市人民医院, 清远 511518

作者简介: 林必桂(1982-),男,工程师,研究方向为环境与健康,E-mail:linbigui@scies.org.

基金项目: 国家自然科学基金(NSFC)-广东联合基金(U1401233)；中央级公益性科研院所基本科研业务费专项资金项目(PM-zx703-201602-042；PM-zx703-201701-013；PM-zx703-201701-034)


中图分类号: X171.5

Human Exposure of Halogenated Persistent Organic Pollutants (Hal-POPs) and Its Potential Effect on Reproductive Health in Indoor Environment

Lin Bigui^1,2,3,
Yu Yunjiang^1,2,3,
Chen Xichao²,
Li Liangzhong²,
Qiao Jing⁴,
Ma Ruixue²,
Xiang mingdeng²
1. State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China;
2. State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou 510655, China;
3. University of Chinese Academy of Sciences, Beijing 100049, China;
4. The People's Hospital of Qingyuan, Qingyuan 511518, China

CLC number: X171.5

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摘要:卤代持久性有机污染物(Hal-POPs)，如多溴联苯醚(PBDEs)、多氯联苯(PCBs)、滴滴涕(DDT)等是环境中广泛存在的全球性有机污染物，同时它们又是内分泌干扰物，是威胁人类生殖健康的重要因素之一。由于人们每天约有 80%以上的时间在室内度过，且室内环境是Hal-POPs人体暴露的主要来源之一，因此室内环境中Hal-POPs对人体内分泌系统的干扰作用及其机理等问题亟待研究，但目前这方面的研究很有限。本文通过综述Hal-POPs在室内环境中的赋存水平和在人体体内的负荷水平及其半衰期，探讨了其对人体内分泌系统尤其是男性生殖健康的影响情况及其可能的机理，并分析了目前研究的不足之处及研究前景，为进一步开展这方面的研究提供借鉴。
关键词: 室内积尘/
卤代持久性有机污染物/
多溴联苯醚/
生殖健康/
健康风险

Abstract:Typical halogenated persistent organic pollutants (Hal-POPs), including polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and DDT etc., are a group of ubiquitous organic pollutants. Hal-POPs are also endocrine disruptors, which are one of the important factors that threaten human endocrine system. People usually spend more than 80% of their time indoor, and indoor environment is one of the main sources for human exposure to Hal-POPs. However, there are few studies about the effect of Hal-POPs on human endocrine system in indoor environment，especially on male reproductive health. Therefore, it is urgent to study the effect of Hal-POPs from indoor environment on human endocrine system, as well as to explore its mechanism. In order to explore such problems, this review summarizes the levels and half-lives of Hal-POPs in indoor environments and in human body. The effect of Hal-POPs to the human endocrine system, especially to male reproductive health, and its possible mechanism are also discussed. Finally, the deficiencies and prospects of the present study are analyzed.
Key words:indoor dust/
halogenated persistent organic pollutants (Hal-POPs)/
polybrominated diphenyl ethers (PBDEs)/
reproductive health/
health risk.