Zhen Yang
Yang Group Admin
ZHEN YANG, Ph.D.
Changjiang Professor of Chemistry
Department of Chemistry
Peking University
CV
EDUCATION
1989-1992 Ph.D., Chemistry, The Chinese University of Hong Kong,with Professor Henry N. C. Wong
1983-1986 M.S., Pharmaceutical Chemistry, Shenyang College of Pharmacy,with Professor Qihuai Chen
1978-1982 B.S., Pharmaceutical Chemistry, Shenyang College of Pharmacy
PROFESSIONAL EXPERIENCE
2002- Changjiang Professor of Chemistry, Dept. of Chemistry, Peking University
2005-2008 Director of Chemistry, XTL biopharmaceutical Inc. NY
2001-2005 Co-founders and Director of Chemistry, VivoQuest Inc. NY
1998-2001 Institute Fellow, Dept. of Cell biology, Harvard Medical School
1995-1998 Assistant professor, Dept. of Chemistry, The Scripps Institute
1992-1995 Postdoctoral Fellow, Dept. of Chemistry, The Scripps Research Institute, with Professor K. C. Nicolaou
HONORS AND AWARDS
2000 The National Science Fund for Distinguished Young Investigator Award (abroad),NSF of China;
2004 The National Science Fund for Distinguished Young Investigator Award, NSF of China;
2005 Eli Lilly Scientific Excellence Award (China);
2008 The Asian Core Program Lectureship Award, the Asian Cutting-Edge Organic Chemistry programs;
2009 Baogang Distinguished Teaching Award of Peking University;
2010 Wuxi Pharma Life Science Excellence Award (Golden Metal)
EDITORAL BOARDS
2007 Advisory Board, Chinese Journal of Organic Chemistry
2010 Advisory Board, Combinatorial Science of ACS
2011 Advisory Board, Advanced Synthesis & Catalysis of Wiley-VCH
2011 Advisory Board, Natural Products and Bioprospecting of Springer
2011 Advisory Board, MedChemComm of RSC Publishing
SELECTIVE PUBLICATIONS
1. Total Syntheses of Drimane-Type Sesquiterpenoids Enabled by a Gold-Catalyzed
Tandem Reaction
H. Shi, L. C. Fang, C. H. Tan, L. L. Shi, W. B. Zhang, C. C. Li, T. P. Luo, Yang, Z.
J. Am. Chem. Soc. 2011, 132, ASAP.
2. Diastereoselective Total Synthesis of (±)-Schindilactone A
Q. Xiao, W. W. Ren, Z. X. Chen, T. W. Sun, Y. Li, Q. D. Ye, J. X. Gong, F. K. Meng, L.
You, Y. F. Liu, M. Z. Zhao, L. M. Xu, Z. H. Shan, Y. Shi, Y. F. Tang, J. H. Chen, Yang, Z.
Angew. Chem. Int. Ed. 2011, 50, 7373.
3. Formal Synthesis of Cortistatins
L. C. Fang, Y. Chen, J. Huang, L. Z. Liu, J. M. Quan, C. C. Li, Yang, Z.
J. Org. Chem. 2011, 76, 2479.
4. A Concise Approach for the Total Synthesis of Pseudolaric Acid A
T. Xu, C. C. Li, Yang, Z.
Org. Lett. 2011, 13, 2630.
5. Asymmetric Total Synthesis and Structural Elucidation of NFAT-68
L. Wang, Y. M. Xi, S. L. Yang, R. Zhu, Y. F. Liang, J. H. Chen, Yang, Z.
Org. Lett. 2011, 13, 74.
6. Total Synthesis of Maoecrystal V
Gong, J.; Lin, G.; Sun, W.; Li, C.-C.; Yang, Z.
J. Am. Chem. Soc., 2010, 132, 16745.
7. Asymmetric Total Synthesis of Caribenol A
Liu, L.; Han, J.; Yue, G.; Li, C.-C.; Yang, Z.
J. Am. Chem. Soc., 2010, 132, 13608.
8. A model study for the concise construction of the oxapentacyclic core of cortistatins
through intramolecular Diels-Alder and oxidative dearomatization-cyclization reaction
Liu, L. Z.; Gao, Y. X.; Che, C.; Wu, N.; Wang, D. Z.; Li, C. C.;Yang, Z.
Chemical Communications 2009, 662-664.
9. Total synthesis of crisamicin A
Li, Z. T.; Gao, Y. X.; Tang, Y. F.; Dai, M. J.; Wang, G. X.; Wang, Z. G.; Yang, Z.
Org. Lett. 2008, 10, 3017-3020.
10. Diversity-Oriented Synthesis of Fused Pyran gamma-Lactones via an Efficient Pd-
Thiourea-Catalyzed Alkoxycarbonylative Annulation
Li, Z. T.; Gao, Y. X.; Jiao, Z. D.; Wu, N.; Wang, D. Z.; Yang, Z.
Org. Lett. 2008, 10, 5163-5166.
11. A One-Pot Synthesis of Quinoline-based Tetracycles by a Tandem Three-Component
Reaction
Che, C.; Xiang, J.; Wang, G. X.; Quan, J.-M.; Yang, Z.
J. Comb. Chem. 2007, 9, 982.
12. Development of a Concise and Diversity-Oriented Approach for the Synthesis of
Plecomacrolides via the Diene-Ene RCM
Lu, K.; Huang, M.; Xiang, Z.; Liu, Y.; Chen, J.; Yang, Z.
Org. Lett. 2006, 8, 1193.
13. Synthetic Study of 1,3-Butadiene-Based IMDA Approach to Construct a [5-7-6]
Tricyclic Core and Its Application to the Total Synthesis of C8-epi-Guanacastepene O
Li, C. ; Wang, C. ; Liang, B. ; Zhang, X. ; Deng, L. ; Liang, S. ; Chen, J. ; Wu, Y. ;
Yang, Z.
J. Org. Chem. 2006, 71, 6892.
14. Thioureas as Ligands in the Pd-Catalyzed Intramolecular Pauson-Khand Reaction
Tang, Y.; Deng, L.; Zhang, Y.; Dong, G.; Chen, J.; Yang, Z.
Org. Lett. 2005, 7, 1657.
15. A Highly Efficient Synthesis of the FGH Ring of Micrandilactone A. Application of
Thioureas as Ligands in the Co-catalyzed Pauson-Khand Reaction and Pd-Catalyzed
Carbonylative Annulation
Tang, Y.; Zhang, Y.; Dai, M.; Luo, T.; Deng, L.; Chen, J.; Yang, Z.
Org. Lett. 2005, 7, 885-888.
16. Total synthesis of Brevetoxin A
Nicolaou, K. C.; Yang, Z.; Shi, G.-Q.; Gunzner, J. L.; Agrios, K. A.; Garttner, P.
Nature 1998, 392, 264-269.
17. Total synthesis of Taxol
Nicolaou, K.C.; Yang, Z.; Liu, J.-J.; Ueno, H.; Nantermet, P.G.; Guy, R.K.; Claiborne,
C.F.; Renaud, J.; Couladouros, E.A.; Paulvannan,K.; Sorensen, E.J.
Nature, 1994, 367, 630-634.
For full publications see CV (PDF)
