夏斌职务：教育部“****奖励计划”特聘教授
北京核磁共振中心主任兼首席科学家
北京大学化学与分子工程学院分析化学专业博士生导师
北京大学生命科学学院生物化学与分子生物学专业博士生导师

个人简历：1989年毕业于北京大学生物系获学士学位
1997年在美国UniversityofWisconsin-Madison
获博士学位
1997年至2001年在美国TheScrippsResearchInstitute
博士后

联系方式：Tel:010－62758127
Fax：010－62753790
E-mail:binxia@pku.edu.cn

研究兴趣：蛋白质结构与功能关系的核磁共振谱学研究
蛋白质的结构基因组学研究
疾病的代谢组学研究


2005年以来主要代表文献：

1. C-terminaldomainofSARS-CoVmainproteasecanforma3Ddomain-swappeddimer.ZhongN,ZhangS,XueF,KangX,ZouP,ChenJ,LiangC,RaoZ,JinC,LouZ,XiaB.ProteinSci.2009Apr;18(4):839-44.PMID:19319935
2. Automics:anintegratedplatformforNMR-basedmetabonomicsspectralprocessinganddataanalysis.WangT,ShaoK,ChuQ,RenY,MuY,QuL,HeJ,JinC,XiaB.BMCBioinformatics.2009Mar16;10:83.PMID:19291281
3. AnovelBcl-XLinhibitorZ36thatinducesautophagiccelldeathinHelacells.
   LinJ,ZhengZ,LiY,YuW,ZhongW,TianS,ZhaoF,RenX,XiaoJ,WangN,LiuS,WangL,ShengF,ChenY,JinC,LiS,XiaB.Autophagy.2009Apr;5(3):314-20.Epub2009Apr16.PMID:19242113
   
4. Solutionstructureofhumanzeta-COP:directevidencesforstructuralsimilaritybetweenCOPIandclathrin-adaptorcoats.YuW,LinJ,JinC,XiaB.JMolBiol.2009Mar6;386(4):903-12.PMID:19167404
   
5. SolutionstructureofGSP13fromBacillussubtilisexhibitsanS1domainrelatedtocoldshockproteins.YuW,HuJ,YuB,XiaW,JinC,XiaB.JBiomolNMR.2009Apr;43(4):255-9.PMID:19152054
   
6. Solutionstructureandcatalyticmechanismofhumanproteinhistidinephosphatase1.GongW,LiY,CuiG,HuJ,FangH,JinC,XiaB.BiochemJ.2009Mar1;418(2):337-44.PMID:18991813
   
7. WithoutitsN-finger,themainproteaseofsevereacuterespiratorysyndromecoronaviruscanformanoveldimerthroughitsC-terminaldomain.ZhongN,ZhangS,ZouP,ChenJ,KangX,LiZ,LiangC,JinC,XiaB.JVirol.2008May;82(9):4227-34.Epub2008Feb27.PMID:18305043
   
8. ¹H,¹³C,and¹⁵Nresonanceassignmentsofhumanζ-COP.WenyuYu,ChangwenJinandBinXia(2008)BiomolecularNMRAssignments20082:73–75.
   
9. ¹H,¹³C,and¹⁵NresonanceassignmentsofageneralstressproteinGSP13fromBacillussubtilis.WenyuYu,BingkeYu,JichengHu,WeiXia,ChangwenJin,BinXia(2008)BiomolecularNMRAssignments20082:163–165
   
10. ¹H,¹³C,and¹⁵Nresonanceassignmentsofhumanphosphohistidinephosphatase1(PHPT1)Weibin,GaofengCui,ChangwenJinandBinXiaBiomolecularNMRAssignments20071:229-231
    
11. GossypolinducesBax/Bak-independentactivationofapoptosisandcytochromecreleaseviaaconformationalchangeinBcl-2.LeiX,ChenY,DuG,YuW,WangX,QuH,XiaB,HeH,MaoJ,ZongW,LiaoX,MehrpourM,HaoX,ChenQ.FASEBJ.2006Oct;20(12):2147-9.Epub2006Aug25.PMID:16935937
    
12. StructuralinsightintopoplarglutaredoxinC1withabridgingiron-sulfurclusterattheactivesite.FengY,ZhongN,RouhierN,HaseT,KusunokiM,JacquotJP,JinC,XiaB.Biochemistry.2006Jul4;45(26):7998-8008.PMID:16800625
    
13. Identificationandsolutionstructuresofasingledomainbiotin/lipoylattachmentproteinfromBacillussubtilis.CuiG,NanB,HuJ,WangY,JinC,XiaB.JBiolChem.2006Jul21;281(29):20598-607.Epub2006May14.PMID:16699181
    
14. PeriplasmicproteinHdeAexhibitschaperone-likeactivityexclusivelywithinstomachpHrangebytransformingintodisorderedconformation.HongW,JiaoW,HuJ,ZhangJ,LiuC,FuX,ShenD,XiaB,ChangZ.JBiolChem.2005Jul22;280(29):27029-34.Epub2005May23.PMID:15911614
    
15. ¹H,¹⁵N,and¹³CresonanceassignmentsofreducedglutaredoxinC1fromPopulustremulaxtremuloides.FengY,RouhierN,JacquotJP,XiaB.JBiomolNMR.2005Mar;31(3):263-4.Noabstractavailable.PMID:15803403
    
16. ¹H,¹³C,and¹⁵NresonanceassignmentsoftheN-terminaldomainoftheSARSCoVnucleocapsidprotein.ZhongN,HuangQ,JinC,XiaB.JBiomolNMR.2005Jan;31(1):79-80.Noabstractavailable.PMID:15692748
    
    
    

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