1. 西北大学化工学院，陕西 西安 7100692. 中国科学院过程工程研究所绿色过程与工程重点实验室，北京 100190
收稿日期:2018-02-19修回日期:2018-04-11出版日期:2018-12-22发布日期:2018-12-19通讯作者:刘庆芬基金资助:水体污染控制与治理科技重大专项;国家自然科学基金资助项目;中国科学院重点部署项目Recovery of cephalexin with complexation
Xin WANG1, Zhengsheng MA1, Qingfen LIU2*1. School of Chemical Engineering, Northwest University, Xi'an, Shaanxi 710069, China; 2. CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
Received:2018-02-19Revised:2018-04-11Online:2018-12-22Published:2018-12-19Contact:Qing-Fen LIU Supported by:Major Science and Technology Project of Water Pollution Control and Management in China摘要/Abstract
摘要： 以苯系和萘系化合物为络合剂，研究头孢氨苄结晶母液中头孢氨苄的富集回收过程，考察了络合剂种类、剂量、pH、温度、残留原料和副产物浓度对头孢氨苄络合过程的影响，确定了关键影响因素，建立和优化了工艺过程. 结果表明，络合剂种类、剂量和pH是影响头孢氨苄络合率的关键因素，其它因素对头孢氨苄络合率无明显影响. 最佳络合工艺为1-萘酚剂量4.4 g/L，pH为4.72，温度293 K，此时头孢氨苄的络合率大于97.0%，比目前生产工艺提高了5.0%.
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王新 马政生 刘庆芬. 头孢氨苄络合回收工艺[J]. 过程工程学报, 2018, 18(6): 1232-1238.
Xin WANG Zhengsheng MA Qingfen LIU. Recovery of cephalexin with complexation[J]. Chin. J. Process Eng., 2018, 18(6): 1232-1238.
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