中文关键词:温敏水凝胶抗菌制备控释 英文关键词:Temperature sensitive hydrogelAntibacterialPreparationControlled release 基金项目:国家自然科学基金项目（31870541，31370568）资助

作者	单位	E-mail
彭锐	浙江农林大学工程学院 杭州 311300
张晶晶	浙江农林大学工程学院 杭州 311300
杜春贵	浙江农林大学工程学院 杭州 311300	chunguidu@163.com
滑亚婷	浙江农林大学工程学院 杭州 311300

摘要点击次数:1145 全文下载次数:0 中文摘要: 温敏水凝胶是一类通过感知温度变化使自身发生相变的智能型聚合物凝胶，通过负载抗菌剂或抗菌性单体制备抗菌水凝胶是近年来药物控制释放、组织工程以及生物免疫等领域关注的热点。本文概述了负载抗菌剂型温敏性抗菌水凝胶的物理交联和化学交联制备技术的研究概况，着重阐述了温敏性抗菌水凝胶的孔径调控、制备材料调控、载药模式调控等技术的研究进展，并对温敏性抗菌水凝胶的控释技术应用前景，特别是在生物质材料领域的应用前景进行了展望。 英文摘要: Thermo-sensitive hydrogels are a class of intelligent polymer gels that undergo a phase change by sensing temperature changes. Preparation of antibacterial hydrogels by loading antibacterial agents or by antibacterial monomers is a hot spot in the fields of drug controlled release, tissue engineering and biological immunity in recent years. In this paper, the research progress in physical crosslinking and chemical crosslinking preparation technology of temperature-sensitive antibacterial hydrogels are reviewed. The control technology, such as the pore diameter, the preparation material and drug loading mode regulation is described. And the application of thermo-sensitive antibacterial hydrogel in controlled release technology, and especially the application prospect in the field of biomass materials are prospected. 查看全文查看/发表评论下载PDF阅读器 相关附件：版权转让声明书 -->