中文关键词:高效液相色谱固定相聚合物整体柱 英文关键词:HPLCstationary phasepolymeric monolith 基金项目:

作者	单位	E-mail
李旻昊	河北工业大学化工学院	liminhao1026@163.com
王泽溟	河北工业大学化工学院
杨杰	河北工业大学化工学院
王家喜	河北工业大学化工学院	wangjiaxi@hebut.edu.cn

摘要点击次数:1264 全文下载次数:0 中文摘要: 高效液相色谱整体柱作为一种新型的分离介质，由于其制备工艺简单、易于修饰改性和分离性能优异，近年来引起了人们的广泛关注。聚合物整体柱具有生物相容性好、柱效高、寿命长、选材范围广、重现性好及使用不受pH值限制等优势，广泛应用于食品、化工、农业、环境及生物医学领域小分子化合物及蛋白质的分离和检测，显示出较好的应用前景。本文就近10年液相色谱整体柱的制备、改性方法及应用的研究成果进行了综述，并对其在不同应用领域的未来发展前景作了展望。 英文摘要: As a new type of separating medium, high performance liquid chromatography (HPLC) monolithic columns have attracted considerable attention on account of its own characteristics, such as the simple preparation process, easy to be modified and excellent separation properties. Especially, due to its favorable biocompatibility, high column efficiency, long life, wide of the raw material source, good repeatability, unrestricted by pH, polymer-based monolithic columns are frequently used to separate and detect some small molecules compounds and proteins in food, chemical industry, agriculture, environment and biomedical science, which have shown a promising application prospect. Refer to the latest reports about HPLC, this review will focus on the research achievements of the preparation, modification method and application of monolithic columns in recent ten years. In addition, the future prospects for development regarding monolithic columns in various fields are expected also. 查看全文查看/发表评论下载PDF阅读器 相关附件：版权 -->