中文关键词:玉米蛋白，吐温-20，姜黄素，包封率，稳定性，荧光光谱 英文关键词:zein, Tween-20, curcumin, encapsulation efficiency, stability, fluorescence 基金项目:国家自然科学基金项目(21573071)

作者	单位	E-mail
褚翔宇	华东理工大学	895538103@qq.com
王小永	华东理工大学	xiaoyong@ecust.edu.cn

摘要点击次数:1410 全文下载次数:0 中文摘要: 本文采用反溶剂沉淀法制备了玉米蛋白/吐温-20复合纳米颗粒。通过测定玉米蛋白/吐温-20复合纳米颗粒对姜黄素的包封率、稳定性及荧光光谱性质，考察了不同浓度吐温-20对玉米蛋白/吐温-20复合纳米颗粒包载姜黄素的影响规律。相比玉米蛋白纳米颗粒，玉米蛋白/吐温-20复合纳米颗粒能够显著提高姜黄素的包封率、稳定性、荧光发射光谱强度和各向异性。这些结果说明姜黄素通过疏水作用缔合于玉米蛋白/吐温-20复合纳米颗粒的疏水微区。吐温-20作为稳定剂不仅有助于生成较小粒径的玉米蛋白/吐温-20复合纳米颗粒，而且吐温-20与玉米蛋白的结合能够为姜黄素提供更适合的疏水缔合环境。 英文摘要: In this paper, zein/Tween-20 composite nanoparticles were prepared by anti-solvent precipitation. By measuring the encapsulation efficiency, stability, and fluorescence properties of curcumin in zein/Tween-20 composite nanoparticles, the influence of Tween-20 concentration on the interaction between zein/Tween-20 composite nanoparticles and curcumin was investigated. Compared to zein nanoparticles, zein/Tween-20 composite nanoparticles can significantly increase the encapsulation efficiency, stability, fluorescence emission intensity, and anisotropy of curcumin. These results indicate that curcumin is bound in hydrophobic domains of zein/Tween-20 composite nanoparticles via hydrophobic interactions. Tween-20 as a stabilizer not only helps to produce smaller zein/Tween-20 composite nanoparticles, but also provides a more suitable hydrophobic binding environment for curcumin. 查看全文查看/发表评论下载PDF阅读器 相关附件：版权转让声明书20180401002修改稿的标注版 -->