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Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targ

本站小编 Free考研考试/2022-01-02
Meng Gao1,2,3,
Jian Huang1,2,3,
Xin Jiang2,3,4,5,
Yafei Yuan2,3,4,
Huanhuan Pang6,
Shuchen Luo1,2,3,
Nan Wang2,3,4,
Chengbo Yao1,2,3,
Zuwan Lin1,2,3,
Debing Pu2,3,6,
Shuo Zhang2,3,4,
Pengcheng Sun2,3,4,
Zhuoyi Liu1,2,3,
Yu Xiao7,
Qian Wang7,
Zeping Hu6,
Hang Yin2,3,6,
1 Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China;
2 Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China;
3 Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100084, China;
4 State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China;
5 Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA;
6 School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China;
7 Laboratory Medicine Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China
Funds: This work was funded by the National Natural Science Foundation of China (Nos. 20181371453, 81861138009, and 31630017) and Beijing Outstanding Young Scientist Program Grand No. BJJWZYJH01201910003013 (H.Y.).






Abstract



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