基本信息
Alberto Macho男博导中国科学院分子植物科学卓越创新中心（植物生理生态研究所）
电子邮件： alberto.macho@sibs.ac.cn
通信地址： 松江区辰花路3888号科研中心317A
邮政编码：
部门/实验室：逆境中心
研究领域植物与细菌相互作用研究

招生信息
招生专业071010-生物化学与分子生物学

招生方向植物与细菌性病原体的交互作用


教育背景2005-01--2010-07西班牙马拉加大学博士
2004-09--2006-09西班牙马拉加大学硕士
1999-09--2004-09西班牙马拉加大学本科学士

学历
学位

工作经历
工作简历2015-01~现在,中国科学研究院上海生命科学研究院,研究员
2011-02~2014-12,英国诺维奇塞恩斯伯里实验室,博士后
2010-08~2011-01,西班牙马拉加大学,博士后

社会兼职

教授课程Plant-Bacteria Interaction
Salicylic Acid
Type III-secreted effectors
Plant Stress Biology


专利与奖励
奖励信息（1） FEBS科学家奖, 一等奖, 其他, 2015
（2） 获得FEBS长期博士后奖, 一等奖, 其他, 2011
（3） 马拉加大学杰出博士生奖, 一等奖, 研究所（学校）, 2010
（4） EMBO 短期奖学金, 一等奖, 其他, 2008

专利成果

出版信息
发表论文（1）Impaired PSII proteostasis promotes retrograde signaling via salicylic acid,Plant Physiology,2019,其他（合作组作者）
（2）TTL proteins scaffold brassinosteroid signaling components at the plasma membrane to optimize signal transduction in Arabidopsis,The Plant Cell,2019,其他（合作组作者）
（3）Molecular dialogues between viruses and receptor-like kinases in plants,Molecular Plant Pathology,2019,通讯作者
（4）Ionic stress enhances ER-PM connectivity via phosphoinositide-associated SYT1 contact site expansion in Arabidopsis.,PNAS,2019,第6作者
（5）A systematic screen of conserved R. solanacearum effectors reveals the role of RipAB, a nuclear-localized effector that suppresses immune responses in potato.,Molecular Plant Pathology,2019,其他（合作组作者）
（6）Cautionary notes on the use of Agrobacterium-mediated transient expression upon SGT1 silencing in Nicotiana benthamiana,New Phytologist,2019,通讯作者
（7）The IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING 9 protein is a regulator of basal immunity in Arabidopsis thaliana,Molecular Plant-Microbe Interactions,2019,通讯作者
（8）Phosphocode-dependent functional dichotomy of the common co-receptor BAK1 in plant signaling,Nature,2019,其他（合作组作者）
（9）Suppression of HopZ effector-triggered plant immunity in a natural pathosystem,Frontiers in Plant Science,2018,第8作者
（10）Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity,Cell Reports,2018,其他（合作组作者）
（11）The Ralstonia solanacearum csp22 peptide, but not flagellin-derived peptides, is perceived by plants from the Solanaceae family,Plant Biotechnology Journal,2018,通讯作者
（12）Confocal microscopy reveals?in planta?dynamic interactions?between pathogenic, avirulent and?non-pathogenic?Pseudomonas syringae?strains.?,Molecular Plant Pathology,2017,第2作者
（13）Transcriptomes of Ralstonia solanacearum?during root colonization of Solanum commersonii,Frontiers in?Plant Science,2017,第5作者
（14）Genome sequencing and analysis of?Ralstonia solanacearum phylotype I strains FJAT-91, FJAT-452 and?FJAT-462?isolated from tomato, eggplant, and chilli pepper in China,Standards in Genomic Sciences,2017,通讯作者
（15）Bacterial?Wilt in China: history, current status and future perspectives,Frontiers in Plant Science,2017,第7作者
（16）The Ralstonia solanacearum type III effector RipAY is phosphorylated in plant cells to modulate its enzymatic activity,Frontiers in Plant Science,2017,通讯作者
（17）Analysis of PAMP-triggered ROS?Burst in Plant Immunity,Methods in Molecular Biology,2017,通讯作者
（18）SUMO proteases?ULP1c and?ULP1d are required for development and osmotic stress responses in?Arabidopsis thaliana,Plant Molecular Biology,2016,第5作者
（19）The Ralstonia solanacearum type-III effector RipAY targets plant redox?regulators to suppress immune responses,Molecular Plant Pathology,2016,通讯作者
（20）The C2 Protein from the Geminivirus Tomato Yellow Leaf Curl Sardinia Virus Decreases Sensitivity to Jasmonates and Suppresses Jasmonate-Mediated Defences,Plants,2016,第2作者
（21）Competitive Index: Mixed Infection-Based Virulence Assays for Genetic Analysis in Pseudomonas syringae-Plant Interactions,Methods in Molecular Biology,2016,第1作者
（22）Immunoprecipitation of Plasma Membrane Receptor-Like Kinases for Identification of Phosphorylation Sites and Associated Proteins,Methods in Molecular Biology,2016,第2作者
（23）Subversion of plant cellular functions by bacterial type-III effectors: beyond suppression of immunity,New Phytologist,2016,第1作者
（24）Targeting of PRR-triggered immunity by type-III effectors from plant pathogenic bacteria,Current Opinion in Microbiology,2015,第1作者
（25）Importance of tyrosine phosphorylation in receptor kinase complexes,Trends in Plant Science,2015,通讯作者
（26）Auto-acetylation on K289 is not essential for HopZ1a-mediated plant defense suppression,Frontiers in Microbiology,2015,第3作者
（27）Plant PRRs and the activation of innate immune signaling,Molecular Cell,2014,第1作者
（28）A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation,Science,2014,第1作者
（29）Negative control of BAK1 by Protein Phosphatase 2A during plant innate immunity,EMBO Journal,2014,第2作者
（30）The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth,eLife,2013,第2作者
（31）Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex,Science,2013,第3作者
（32）Aspartate Oxidase plays an important role in Arabidopsis stomatal immunity,Plant Physiology,2012,第1作者
（33）Genetic analysis of the individual contribution to virulence of the type III effector inventory of Pseudomonas syringae pv. Phaseolicola,PLoS One,2012,第1作者
（34）Insights into plant immunity signaling: The bacterial competitive index angle,Plant Signaling & Behavior,2010,第1作者
（35）The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunity,New Phytologist,2010,第1作者
（36）A competitive index assay identifies several Ralstonia solanacearum Type III effector mutant strains with reduced fitness in host plants,Molecular Plant-Microbe Interactions,2010,第1作者
（37）Approaching the role of the type III effector inventory of Pseudomonas syringae pv. phaseolicola 1448a in the interaction with the plant,Journal of Bacteriology,2010,第2作者
（38）Positive regulation of the Hrp type III secretion system in Pseudomonas syringae pv. Phaseolicola,Molecular Plant-Microbe Interactions,2010,第3作者
（39）Identification of new type III effectors and analysis of the plant response by competitive index,Molecular Plant Pathology,2009,第1作者
（40）Early detection of bean infection by Pseudomonas syringae in asymptomatic leaf areas using chlorophyll fluorescente imaging,Photosynthesis research,2008,第4作者
（41）Competitive index in mixed infections: a sensitive and accurate assay for the genetic analysis of Pseudomonas syringae-plant interactions,Molecular Plant Pathology,2007,第1作者
（42）Suicide vectors for antibiotic marker exchange and rapid generation of multiple knockout mutants by allelic exchange in Gram-negative bacteria,Journal of Microbiological Methods,2006,第2作者

发表著作（1）Competitive Index in Mixed Infection: A Sensitive and Accurate Method to Quantify Growth of Pseudomonas syringae in Different Plants, in Pseudomonas syringae Pathovars and Related Pathogens,Springer,2008-06,第1作者
（2）Chlorophyll Fluorescence Imaging for Detection of Bean Response to Pseudomonas syringae in Asymptomatic Leaf Areas, in Pseudomonas syringae Pathovars and Related Pathogens,Springer,2008-06,第4作者


科研活动
科研项目（ 1 ） 植物细菌病原体毒性的激活机制研究, 主持,国家级,2016-01--2019-12
（ 2 ） 中央**** 青年项目, 主持,国家级,2015-01--2018-12
（ 3 ） 病原体侵染与植物营养代谢相互作用的机制研究, 主持,部委级,2018-06--2023-05

参与会议（1）The molecular interface between plants and Ralstonia solanacearum: beyond activation and suppression of immunity2019-06-26
（2）An immune receptor complex evolved to perceive the polymorphic flagellin from Ralstonia solanacearum2019-06-24
（3）Ralstonia solanacearum subverts plant metabolism to support bacterial nutrition and cause bacterial wilt disease2019-06-19
（4）The molecular interface between plants and Ralstonia solanacearum: beyond activation and suppression of immunity2018-08-01
（5）Deciphering the molecular interface between plants and bacterial pathogens.2018-05-01
（6）Deciphering the subversion of plant cellular functions by Ralstonia solanacearum type-III effectors2017-09-15
（7）Analyses of plant immunity and the disruption by bacterial effectors2016-11-30
（8）current work on thé plant pathogen Ralstonia solanacearum2016-07-05
（9）Characterizing bacterial type-III effectors to decipher the molecular interface between plants and bacterial pathogensAlberto Macho2016-01-10
（10）Bacterial type-III effectors and the suppression of plant immune signallingAlberto Macho2015-06-04
（11）A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activationAlberto Macho2014-10-01
（12）A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activationAlberto Macho2014-09-01
（13）Role of phosphorylation in the activation of plant innate immune receptorsAlberto Macho2014-08-01
（14）A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activationAlberto Macho2014-07-01
（15）Role of phosphorylation in surface immune receptor complexes and its targeting by a bacterial effector proteinAlberto Macho2012-10-01
（16）The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunityAlberto Macho2012-07-15
（17）The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunityAlberto Macho2012-07-01
（18）The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunityAlberto Macho2012-05-01
（19）The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunityAlberto Macho2010-08-01


合作情况
项目协作单位

指导学生已指导学生
王远征博士研究生071010-生物化学与分子生物学
现指导学生
鲜刘博士研究生071010-生物化学与分子生物学
王亚如博士研究生071010-生物化学与分子生物学
罗佳敏博士研究生071010-生物化学与分子生物学
魏雅丽博士研究生071010-生物化学与分子生物学
薛好硕士研究生071010-生物化学与分子生物学
刘昕硕士研究生0710J3-生物信息学
于文佳博士研究生071010-生物化学与分子生物学
赵阿晨硕士研究生071007-遗传学