姓名：张建亮 性别：男 职称：副教授 招生院所：基础医学院 招生类型：科学学位(硕) 招生专业：神经生物学(硕) 研究方向名称：帕金森病相关蛋白的结构-功能关系 电子信箱：jlzhang@ccmu.edu.cn


社会任职
个人简历
1. 200109-200408:中国科学院动物研究所 攻读博士
2. 200411-200503:澳大利亚联邦科学和工业研究组织（CSIRO） 访问
3. 200504-200603:中国科学院植物所 助理研究员
4. 200604-200905:美国Barrow神经研究所 博士后
5. 200906-201006:比利时鲁汶大学医学院 博士后
重要学术论文
1. Xiaoxi Ren, Yun Zhao, Fenqin Xue, Yan Zheng, Haixia Huang, Wei Wang, Yongchang Chang, Hui Yang, Jianliang Zhang*.Exosomal DNA Aptamer Targeting a-Synuclein Aggregates Reduced Neuropathological Deficits in a Mouse Parkinson’s Disease Model. Molecular Therapy-Nucleic Acids. 2019,17:726-740.SCI
2. Jing Qu, Hongxia Yan, Yuan Zheng, Fenqin Xue, Yan Zheng, Hongjuan Fang, Yongchang Chang, Hui Yang, Jianliang Zhang*.The molecular mechanism of alpha-synuclein dependent regulation of protein Phosphatase 2A activity. Cellular Physiology and Biochemistry. 2018,47(6):2613-2625.SCI
3. Qi Wang, Bing Xiao, Shuqin Cui, Hailong Song, Yanjing Qian, Lin Dong, Haiting An, Yanqiu Cui, Wenjing Zhang, Yi He, Jianliang Zhang, Jian Yang, Feilong Zhang, Guanzheng Hu, Xiaoli Gong, Zhen Yan, Yan Zheng, and Xiaomin Wang.Triptolide with multiple modes of action improves learning performance in the 5XFAD Alzheimer's disease mouse model. Disease Models & Mechanisms. 2014,7:1385-1395.SCI
4. Jiamei Shen, Tingting Du, Xue Wang, Chunli Duan, Ge Gao, Jianliang Zhang, Lingling Lu, Hui Yang.α-Synuclein amino terminus regulates mitochondrial membrane permeability. Brain Research. 2014,1591:14-26.SCI
5. Jianliang Zhang*, Fenqin Xue, Yujun Liu, Hui Yang, Xiaomin Wang.The Structural Mechanism of the Cys-Loop Receptor Desensitization. Molecular Neurobiology. 2013,48(3):97–108.SCI
6. Qiang Liu, Yao Huang, Fenqin Xue, Alain Simard, Jamie Dechon, Guohui Li, Jiangliang Zhang, Linda Lucero, Min Wang, Michael Sierks, Gang Hu, Yongchang Chang, Ron Lukas, and Jie Wu.A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. Journal of Neuroscience. 2009,29(4):918-929.SCI
7. Jianliang Zhang, Fenqin Xue, Yongchang Chang.Agonist- and antagonist-induced conformational changes of loop F and their contributions to the ρ1 GABA receptor function. Journal of Physiology (London). 2009,587(1):139-153.SCI
8. Jianliang Zhang, Fenqin Xue, and Yongchang Chang.Structural Determinants for Antagonist Pharmacology That Distinguish the rho1 GABARCR Receptor from GABARAR Receptors. Molecular Pharmacology. 2008,74(4) :941-951.SCI
9. Jie Wu, Yongchang Chang, Guohui Li, Fenqin Xue, Jamie DeChon, Kevin Ellsworth, Qiang Liu, Kechun Yang, Nasim Bahadroani, Chao Zheng, Jianliang Zhang, Harold Rekate, Jong M. Rho, and John F. Kerrigan.Electrophysiological Properties and Subunit Composition of GABAA Receptors in Patients With Gelastic Seizures and Hypothalamic Hamartoma. Journal of Neurophysiology. 2007,98:5–15.SCI
主编或副主编的著作/译著
重要奖项