姓名：程杉 性别：女 职称：副教授 招生院所：基础医学院 招生类型：科学学位(硕) 招生专业：遗传学(硕) 研究方向名称：肿瘤分子生物学 电子信箱：chengs@ccmu.edu.cn


社会任职
个人简历
1. 199609-200006:沈阳药科大学 学习
2. 200009-200306:沈阳药科大学 学习
3. 200309-200607:清华大学 学习
4. 200608-202012:首都医科大学 任职
重要学术论文
1. Yang F, Hu M, Chang S, Huang J, Si Y, Wang J, Cheng S*, Jiang WG.Alteration in the sensitivity to crizotinib by Na+/H+ exchanger regulatory factor 1 is dependent to its subcellular localization in ALK-positive lung cancers. BMC Cancer. 2020,20(1):202.SCI
2. Cui M, Lu Y, Tang C, Zhang R, Wang J, Si Y, Cheng S*, Ding W.A Generic Method for Fast and Sensitive Detection of Adeno-Associated Viruses Using Modified AAV Receptor Recombinant Proteins. Molecules. 2019,24(21):pii: E3973..SCI
3. 黄晶, 牛欢, 程杉*.真核基因剪接作用的调控机理及其在人类疾病中作用的研究进展. 生理科学进展. 2019,50(6):451.
4. Hao C, Cui Y, Chang S, Huang J, Birkin E, Hu M, Zhi X, Li W, Zhang L, Cheng S*, Jiang WG*.OPN promotes the aggressiveness of non-small-cell lung cancer cells through the activation of the RON tyrosine kinase. Sci Rep. 2019,9(1):18101.SCI
5. Huang J, Chang S, Lu Y, Wang J, Si Y, Zhang L, Cheng S*, Jiang WG.Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells. Cancer Cell Int. 2019,9:306.SCI
6. Yanan Gu#, Hefen Yu#, Chengcheng Hao, Tracey A Martin, Rachel Hargest, Junqi He, Shan Cheng*, Wen G Jiang*.NHERF1 regulates the progression of colorectal cancer through the interplay with VEGFR2 pathway. Oncotarget. 2017,8(5):7753-7765.
7. Yang F, Gu Y, Zhao Z, Huang J, Jiang WG, Cheng S*.NHERF1 Suppresses Lung Cancer Cell Migration by Regulation of Epithelial-Mesenchymal Transition. Anticancer Res. 2017,37(8):4405-4414.SCI
8. Hao C, Cui Y, Hu MU, Zhi X, Zhang L, Li W, Wu W, Cheng S*, Jiang WG*.OPN-a Splicing Variant Expression in Non-small Cell Lung Cancer and its Effects on the Bone Metastatic Abilities of Lung Cancer Cells In Vitro. Anticancer Res. 2017,37(5):2245-2254.SCI
9. Guifang Du, Yanan Gu, Chengcheng Hao, Zhu Yuan, Junqi He, Wen G Jiang, Shan Cheng *. .The cellular distribution of Na+/H+ exchanger regulatory factor 1 is determined by the PDZ-I domain and regulates the malignant progression of breast cancer. Oncotarget. 2016,7(20):29440-29453.
10. Hao C, Wang Z, Gu Y, Jiang WG, Cheng S*.Prognostic Value of Osteopontin Splice Variant-c Expression in Breast Cancers: A Meta-Analysis. Biomed Res Int. 2016,2016:**.SCI
11. Meng Zhao, Wang Jia, Wen G Jiang, Pilin Wang, Guifang Du, Shan Cheng*, Maomin Song*.ADAM29 expression in human breast cancer and its effects on breast cancer cells in vitro. Anticancer Res. 2016,36 (3):1251-1258.SCI
12. Guifang Du, Chengcheng Hao, Yanan Gu, Zhiyan Wang, Wen G Jiang, Junqi He*, Shan Cheng*.A mutation of PDZ protein NHERF1 isolated from human Breast cancer crippled inhibition on epidermal growth factor receptor signaling. Anticancer Res. 2016,36 (3):1165-1173.SCI
13. Guifang Du#, Xiaomei Yang#, Mu Hu, Chengcheng Hao, Yanan Gu, Xiuyi Zhi, Wen G. Jiang, Junqi He*, Shan Cheng*.Designing a novel high-throughput AlphaLISA assay to quantify plasma NHERF1 as a non-small cell lung cancer biomarker. RSC Adv. 2015,5:84164-84171.SCI
14. Shan Cheng#, Yang Li#, Ying Yang, Duiping Feng, Longyan Yang, Qian Ma, Shuai Zheng , Ran Meng, Shuhui Wang, Songlin Wang, Wen G. Jiang, Junqi He.Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling. Febs Lett. 2013,587:3289-3295.SCI
15. Cheng S, Martin TA, Teng X, Jiang WG*..Putative Breast Tumor Suppressor TACC2 Suppresses the Aggressiveness of Breast Cancer Cells through a PLCγ Pathway. Current Signal Transduction Therapy. 2011,6:55-64.SCI
主编或副主编的著作/译著
1. 《医学分子生物学》,主编,高等教育出版社,201703
2. 《Biochemistry》,副主编,高等教育出版社,201206
3. 《 基因克隆与操作》,主译,科学出版社,201005
重要奖项