姓名：谢萍 性别：女 职称：副教授 招生院所：基础医学院 招生类型：科学学位(硕) 招生专业：细胞生物学(硕) 研究方向名称：蛋白质泛素化和类泛素化修饰研究 电子信箱：xiep@ccmu.edu.cn


社会任职
1. 中华医学会细胞生物学会青年委员会委员
2. 北京专家联谊会会员
3. 中国细胞生物学会会员
个人简历
1. 200809-201107:清华大学生命科学学院 博士
2. 201108-201508:北京蛋白质组研究中心 助理研究员/副研究员
3. 201511-:首都医科大学基础医学院 副教授
重要学术论文
1. Xin Zhang#, Yutao Zhan#,Wenjun Lin,Fei Zhao,Chaojing Guo,Yujiao Chen,Mengge Du,Dongnian Li,Wei An*,Hong-Rui Wang*,Ping Xie*.Smurf1 aggravates non-alcoholic fatty liver disease by stabilizing SREBP-1c in an E3 activity independent manner. The FASEB Journal . 2020,accepted:in publish.SCI
2. Liu L#, Xie P#, Li W, Wu Y, An W*.Augmenter of Liver Regeneration Protects against Ethanol-Induced Acute Liver Injury by Promoting Autophagy. Am J Pathol. 2019,189(3):552-567.SCI
3. Tan Y#, Chen Y#, Du M, Peng Z*, Xie P*. USF2 inhibits the transcriptional activity of Smurf1. Cellular Signalling. 2019,53:49-58.SCI
4. Benoit Miotto,Claire Marchal,Guillaume Adelmant,Nadège Guinot,Ping Xie,Jarrod A. Marto,Lingqiang Zhang,Pierre-Antoine Defossez.Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells. nucleic acids research. 2018,46(9): 4392-4404.SCI
5. Yang Li#, Ping Xie#, Liang Lu#, Jian Wang, Lihong Diao, Zhongyang Liu, Feifei Guo, Yangzhige He, Yuan Liu, Qin Huang, Han Liang, Dong Li & Fuchu He.An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network. Nature Communications. 2017,8(1):347.SCI
6. Shuai Tong, Yang Si, Hefen Yu, Lingqiang Zhang, Ping Xie*,Wenguo Jiang*.MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma. Scientific Reports. 2017,7(1):5599.SCI
7. Zhan Y#, Xie P#, Li D, Li L, Chen J, An W, Zhang L, Zhang C*..Deficiency of CKIP-1 aggravates high-fat diet-induced fatty liver in mice. Experimental Cell Research. 2017,355(1):40-46 .SCI
8. Li H#, Zhu H, Liu Y, He F, Xie P*, Zhang L*. .Itch promoters the neddylation of JunB and regulates JunB-dependent transcription. Cellular Signalling. 2016,28(9):1186-95.SCI
9. Li D#, Xie P#, Zhao F, Shu J, Li L, Zhang L*, Zhan Y*. .F Box Protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation. Biochemical and Biophysical Res Communications. 2015,458(4):941-945.SCI
10. Zhao F#, Xie P#, Jiang J, Zhang L, An W, Zhan Y*. .Effect and mechanism of tamoxifen inducing hepatocyte steatosis in vitro. International Journal of Molecular Sciences. 2014,15(3):4019-4030.SCI
11. Miotto B#, Chibi M#, Xie P#, Koundrioukoff S, Moolman-Smook H, Pugh D, Debatisse M, He F, Zhang L*, Defossez PA*. .A new pathway regulating DNA replication and common fragile site stability: the RBBP6/ZBTB38/MCM10 axis. Cell Reports. 2014,7(2):575-87.SCI
12. Xie P#, Zhang M#, He S#, Lu K, Chen Y, Xing G, Lu Y, Liu P, Li Y, Wang S, Chai N, Wu J, Deng H, Wang H, Cao Y, Zhao F, Cui Y, Wang J, He F*, Zhang L*..Covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis. Nature Communications. 2014,5(13):3733.SCI
13. Xie P#, Li L, Xing G, Tian C, Yin Y, He F*, Zhang L*. .ATM-mediated NuSAP phosphorylation induces mitotic arrest. Biochemical and Biophysical Research Communications. 2011,404(1):413-418.SCI
14. Xie P#, Tang Y, Shen S, Wang Y, Xing G, Yin Y, He F*, Zhang L*..Smurf1 ubiquitin ligase targets Kruppel like factor KLF2 for ubiquitination and degradation in human lung cancer H1299 cell. Biochemical and Biophysical Research Communications. 2011,407(1):254-259.SCI
15. Xie P#, Tian C, An L, Nie J, Lu K, Xing G, Zhang L*, He F*. .Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes. Cellular Signalling. 2008,20(9):1671-1678.SCI
主编或副主编的著作/译著
重要奖项
1. 北京市科学技术一等奖 蛋白质稳态调控的翻译后修饰机制 1 201712
2. 第八批北京市优秀青年人才 北京市优秀青年人才 1 201701
3. 2016年北京市科技新星 北京市科技新星 1 201601