姓名：张晨 性别：男 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：神经生物学(博) 神经生物学(硕) 研究方向名称：阿尔兹海默症和孤独症发病机制研究 电子信箱：**@163.com


社会任职
1. 中国实验动物学会第七届理事会-理事
2. 中国神经科学学会-理事
3. 中国生物物理学会-理事
4. 北京大学医学部孤独症研究中心
个人简历
1. 199409-199807:中国科学技术大学 学习
2. 199809-200307:中国科学院上海神经科学研究所 学习
3. 200407-200807:美国德克萨斯西南医学中心（达拉斯） 任职
4. 200808-200907:斯坦福大学 任职
5. 201009-201803:北京大学 任职
6. 201803-201805:首都医科大学 任职
重要学术论文
1. Chen YQ, Zhang C#, Dong W#, Yang XF#.Molecular Mechanisms of Neurotransmitter Release. Chinese Journal of Cell Biology. 2019,41(1): 33-41.核心期刊
2. Wang Y, Su F, Wang S, Yang C, Tian Y, Yuan P, Liu X, Xiong W, Zhang C#.Efficient Implementation of Convolutional Neural Networks in the Data Processing of Two-Photon In Vivo Imaging. Bioinformatics. 2019,23:3549-3562.SCI
3. Yang H#, Yang C#, Zhu Q, Wei M, Li Y, Cheng J, Liu F, Wu Y, Zhang J, Zhang C*, Wu H*. . Rack1 Controls Parallel Fiber-Purkinje Cell Synaptogenesis and Synaptic Transmission. Front Cell Neurosci . 2019,13:539.SCI
4. Zhang L, Wei M, Shao L, Li M, Dai W, Cui Y, Li Z, Zhang C#, Wang W#.Enhanced parylene-C fluorescence as a visual marker for neuronal electrophysiology applications. Lab on a chip. 2018,18(23):3539-3549.SCI
5. Tian Y#, Yang C#, Cui Y#, Su F#, Wang Y#, Wang Y#, Yuan P, Shang S, Li H7, Zhao J, Zhu D, Tang S, Cao P, Liu Y, Wang X, Wang L, Zeng W, Jiang H, Zhao F, Luo M, Xiong W, Qiu Z*, Li XY*, Zhang C*.An excitatory neural assembly encodes short-term memory in the prefrontal cortex. Cell Rep. 2018,22(7):1734-1744.SCI
6. Mengping Wei#, Moye Jia# , Jian Zhang# , Lulu Yu, Yunzhi Zhao,Yingqi Chen,Yimeng Ma, Wei Zhang,Yun S. Shi, Zhang C*.The inhibitory effect of α/β-hydrolase domain-containing 6 (ABHD6) on the surface targeting of GluA2- and GluA3-containing AMPA receptors. Front Mol Neurosci. 2017,10:55.SCI
7. Tian Y#, Yang C#, Shang S#, Cai Y#, Deng X#, Zhang J, Shao F, Zhu D, Liu Y, Chen G, Liang J*, Sun Q*, Qiu Z*, Zhang C*.Loss of FMRP Impaired Hippocampal Long-Term Plasticity and Spatial Learning in Rats. Front Mol Neurosci. 2017,10:269.SCI
8. Wei Jiang #,Mengping Wei# , Mengna Liu#,Yunlong Pan,Dong Cao,Xiaofei Yang*, Zhang C*.Identification of Protein Tyrosine Phosphatase Receptor Type O (PTPRO) as a Synaptic Adhesion Molecule that Promotes Synapse Formation. Journal of Neuroscience. 2017,37(41):9828-9843.SCI
9. Su F#, Yuan P#, Wang YZ#, Zhang C*.The superior fault tolerance of artificial neural network training with a fault/noise injection-based genetic algorithm. Protein& Cell. 2016,7(10):735-748.SCI
10. Wei M#, Zhang J#,Jia M#, Yang C#, PanY,Li S, Luo Y, Zheng J,Ji J,Chen J,Hu X, Xiong J, Shi Y, Zhang C*.α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors. Proceedings of the National Academy of Sciences of the United States of America. 2016,113(19): E2695-E2704.SCI
11. Shang S#, Wang C#, Guo C#, Huang X, Wang L*, Zhang C* .The formation and extinction of fear memory in tree shrews. Frontiers in behavioral neuroscience. 2015,9:204.SCI
12. Hua R, Wei MP, Zhang C*.The complex genetics in autism spectrum disorders. Sci China Life Sci. 2015,58:933–945.SCI
13. Jiang W#, Hua R#, Wei M#, Li C, Qiu Z, Yang X*,Zhang C*.An optimized method for high-titer lentivirus preparations without ultracentrifugation. Sci Rep. 2015,5:13875.SCI
14. Meng Y# , Li H #, Hua R #, Wang H, Lu J, Yu X* , Zhang C*.A correlativity study of plasma APL1beta28 and clusterin levels with MMSE/MoCA/CASI in aMCI patients. Scientific Reports. 2015,5:15546.SCI
15. Yang X*, Hou D, Jiang W, Zhang C*.Intercellular protein-protein interactions at synapses. Protein Cell. 2014,5(6):420-444.SCI
16. Cheng J, Dong J, Cui Y, Wang L, Wu B*, Zhang C*.Interacting partners of AMPA-type glutamate receptors. J Mol Neurosci. 2012,48: 441–447.SCI
17. Zhang C#, Atasoy D, Arac D, Yang X, Fucillo MV, Robison AJ, Ko J, Brunger AT, Südhof TC*.Neurexins physically and functionally interact with GABAA receptors. Neuron. 2010,66(3):403-416.SCI
18. Zhang D#, Zhang C#, Ho A#, Kirkwood A, Südhof TC, Shen J*.Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction. J Neurochem. 2010,115:1215–1221.SCI
19. Zhang C#, Wu B, Beglopoulos V, Wines-Samuelson M, Zhang D, Dragatsis I, Südhof TC, Shen J*.Presenilins are essential for regulating neurotransmitter release. Nature. 2009,460(7255):632–636.SCI
20. Zhang C#, Milunsky JM, Newton S, Ko J, Zhao G, Maher TA, Tager-Flusberg H, Bolliger MF, Carter AS, Boucard AA, Powell CM, Südhof TC*.A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export. J Neurosci . 2009,29(35): 10843–10854.SCI
21. Zhang C#, Xiong W#, Zheng H, Wang L, Lu B, Zhou Z*.Calcium- and dynamin-independent endocytosis in dorsal root ganglion neurons. Neuron . 2004,42(2):225–236.SCI
22. Bao L#, Jin SX#, Zhang C#, Wang LH, Xu ZZ, Zhang FX, Wang LC, Ning FS, Cai HJ, Guan JS, Xiao HS, Xu ZQ, He C, Hokfelt T, Zhou Z*, Zhang X..Activation of Delta Opioid Receptors Induces Receptor Insertion and Neuropeptide Secretion. Neuron. 2003,37(1):121-133.SCI
23. Fan CX#, Chen XK#, Zhang C#, Wang LX, Duan KL, He LL, Cao Y, Liu SY, Zhong MN, Ulens C, Tytgat J, Chen JS, Chi CW, Zhou Z*.A novel conotoxin from conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator. J Biol Chem. 2003,278(15):12624–12633.SCI
24. Zhang C, Zhou Z*.Ca(2+)-independent but voltage-dependent secretion in mammalian dorsal root ganglion neurons. Nat Neurosci. 2002,5:425–430.SCI
主编或副主编的著作/译著
1. 《孤独症谱系障碍》,主编,北京大学医学出版社,201803
重要奖项
1. 高等学校科学研究优秀成果奖 高等学校科学研究优秀成果奖 省部级一等奖 201712
2. 通化东宝生命科学奖 东宝老师奖 校级奖励 201512
3. 北京大学优秀班主任 北京大学优秀班主任 校级奖励 201506
4. 北京大学第七届实验技术成果奖 北京大学第七届实验技术成果奖 校级奖励 201310
5. 绿叶生物医药奖 绿叶生物医药奖 校级奖励 201212
6. 优秀青年科学基金项目 优秀青年科学基金项目 省部级奖励 201208
7. 新世纪优秀人才支持计划 新世纪优秀人才支持计划 省部级奖励 201101
8. 全国百篇优秀博士论文奖 全国百篇优秀博士论文奖 省部级奖励 200510
9. 上海市优秀博士论文奖 上海市优秀博士论文奖 省部级奖励 200501
10. 中国科学院优秀博士论文奖 中国科学院优秀博士论文奖 省部级奖励 200410
11. 中国科学院院长特别奖 中国科学院院长特别奖 省部级奖励 200209