姓名：李俊发 性别：男 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：神经生物学(博) 神经生物学(硕) 研究方向名称：脑卒中损伤和干预分子机制研究 电子信箱：junfali@ccmu.edu.cn


社会任职
1. 《生理通讯》副主编
2. 《基础医学与临床》副主编
3. 北京生理科学会 理事长
4. 中国生理学会 秘书长
个人简历
1. 198109-198608:首都医科大学 医学学士
2. 198608-198908:北京医学高等专科学校(现首都医科大学燕京医学院) 助教，兼校团委书记
3. 198908-199206:中国协和医科大学 医学硕士
4. 199206-199602:北京医学高等专科学校(现首都医科大学燕京医学院) 讲师，兼教务处副处长
5. 199602-200102:美国国立卫生研究院(NIH) 访问
6. 200102-200612:首都医科大学神经生物学系 副研究员/副教授、副主任
7. 200308-200607:首都医科大学 神经生物学博士
8. 200501-200912:首都医科大学分子生物学实验测试室 主任
9. 200701-200712:首都医科大学神经生物学系 教授、博导、副主任
10. 200801-201812:首都医科大学神经生物学系 教授、博导、系常务副主任
11. 201901-:首都医科大学神经生物学系 教授、博导
重要学术论文
1. Lv Y, Lin Z, Li D, Han S, Zhang N, Zhang H, Li J(李俊发)*.cPKCβII is significant to hypoxic preconditioning in mice cerebrum. Front Biosci (Landmark Ed). 2020,25:683-698.SCI
2. Lv Y, He XY, Li D, Liu T, Wen GQ, Li J(李俊发)*.Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans. PLoS One. 2020,15(1):e**.SCI
3. Liu T, Han S, Dai Q, Zheng J, Liu C, Li S, Li J(李俊发)*.IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway. Front Immunol.. 2020,Dec 20:10.3389/fimmu.2019.02952.SCI
4. Wang J, Zhao Q, Zhou Y, Sun W, Han S, Peng Y, Li J(李俊发)*, Han R*.Subanesthetic Dose of Ketamine Improved CFA-induced Inflammatory Pain and Depression-like Behaviors Via Caveolin-1 in Mice. J Neurosurg Anesthesiol. 2019,May 17:doi: 10.1097/ANA.0610.SCI
5. Dai Q, Li S, Liu T, Zheng J, Han S, Qu A, Li J (李俊发)*.IL-17A-mediated alleviation of cortical astrocyte ischemic injuries affected the neurological outcome of mice with ischemic stroke. Journal of Cellular Biochemistry. 2019,2019:1-12.SCI
6. Wang S, Cui W, Zeng M, Ren Y, Han S, Li J (李俊发).The increased release of amino acid neurotransmitters of the primary somatosensory cortical area in rats contributes to remifentanil-induced hyperalgesia and its inhibition by lidocaine. Journal of Pain Research. 2018,11:1521-1529.SCI
7. Cui W, Ren Y, Wang S, Zeng M, Han S, Li J(李俊发)*.The role of caveolin-1 in morphine-induced structural plasticity in primary cultured mouse cerebral cortical neurons. Neuroscience Letters. 2018,665:38-42.SCI
8. Hua R, Han S, Zheng N, Dai Q, Liu T, Li J(李俊发)*.cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/ Reperfusion. International Journal of Molecular Sciences. 2018,19(5):1380.SCI
9. Zheng J, Wang Y, Han S, Luo Y, Sun X, Zhu N, Zhao L, Li J(李俊发)*.Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice. Journal of Diabetes Research. 2018,6:1-9.SCI
10. Zhang N, Zhu H, Han S, Sui L, Li J (李俊发)*.cPKCγ alleviates ischemic injury through modulating synapsin Ia/b phosphorylation in neurons of mice. Brain Res Bull. 2018,142:156-162.SCI
11. Luo YL, Bian JW, Zheng ZJ, Zhao L, Han S, Sun XH, Li JF (李俊发)*, Ni GX*.Effects of methamphetamine abuse on spatial cognitive function. Scientific Reports. 2018,8(1):5502.SCI
12. Wang Y, Han S, Han R, Su Y, Li J(李俊发)*.Propofol-induced down regulation of NR2B membrane translocation in hippocampus and spatial memory deficits of neonatal mice. Brain and Behavior. 2017,7(7):e00734.SCI
13. Liu S, Dai Q, Hua R, Liu T, Han S, Li S, Li J(李俊发)*.Determination of Brain-Regional Blood Perfusion and Endogenous cPKCγ Impact on Ischemic Vulnerability of Mice with Global Ischemia. Neurochemical Research. 2017,42(10):2814-2825.SCI
14. Li S, Dai Q, Yu J, Liu T, Liu S, Ma L, Zhang Y, Han S, Li J(李俊发)*.Identification of IL-17A-derived neural cell type and dynamic changes of IL-17A in serum/CSF of mice with ischemic stroke. Neurological Research. 2017,39(6):552-558.SCI
15. Wang X, Ma W, Han S, Meng Z, Zhao L, Yin Y, Wang Y, Li J(李俊发)*.TGF-β participates choroid neovascularization through Smad2/3-VEGF/TNF-α signaling in mice with Laser-induced wet age-related macular degeneration. Scientific Reports. 2017,7(1):9672.SCI
16. Zhang D, Han S, Wang S, Luo Y, Zhao L, Li J(李俊发)*.cPKCγ-mediated downregulation of UCHL1 alleviates ischemic neuronal injuries by decreasing autophagy via ERK-mTOR pathway. Journal of Cellular and Molecular Medicine. 2017,21(12):3641-3657.SCI
17. Fu T, Wang J, Moran Levin, Xi P, Li, D, Li J(李俊发)*.Clinical features of acute acquired comitant esotropia in the Chinese populations. Medicine. 2017,96(46):e8528.SCI
18. Wang X, Su J, Ding J, Han S, Ma W, Luo H, Hughes G, Meng Z, Yin Y, Wang Y, Li J(李俊发)*.α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension. Drug Des Devel Ther. 2016,10:3449-3457.SCI
19. Yang X, Zhang X, Li Y, Han S, Howells DW, Li S, Li J(李俊发)*.cPKCβ-mediated phosphorylation inhibits CRMP2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice. Journal of Neurochemistry. 2016,137:446-459.SCI
20. Cui W, Wang S, Han R*, Wang Q, Li J(李俊发)*.CaMKII Phosphorylation in Primary Somatosensory Cortical Neurons is Involved in the Inhibition of Remifentanil-induced Hyperalgesia by Lidocaine in Male Sprague-Dawley Rats. Journal of Neurosurgical Anesthesiology. 2016,28(1):44-50.SCI
21. Zhang N, Zhong J, Han S, Li Y, Yin Y, Li J(李俊发)* .MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3. International Journal of Molecular Sciences. 2016,17(9):1427.SCI
22. Meng F, Li Y, Chi W, Li J(李俊发)*.Morphine Preconditioning Downregulates MicroRNA-134 Expression Against Oxygen-Glucose Deprivation Injuries in Cultured Neurons of Mice. Journal of Neurosurgical Anesthesiology. 2016,28(3):195-202.SCI
23. Yang X, Zhang X, Li Y, Han S, Howells DW, Li S*, Li J(李俊发)*.cPKCβ-mediated phosphorylation inhibits CRMP2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice. Journal of Neurochemistry. 2016,137:446-459.SCI
24. Wei H, Li Y, Han S, Liu S, Zhang N, Zhao L, Li S, Li J(李俊发)*.cPKCγ-Modulated Autophagy in Neurons Alleviates Ischemic Injury in Brain of Mice with Ischemic Stroke Through Akt-mTOR Pathway. Translational Stroke Research. 2016,7(6):497-511.SCI
25. Liu C, Zhao L, Han S, Li J(李俊发)*, Li D*.Identification and Functional Analysis of MicroRNAs in Mice following Focal Cerebral Ischemia Injury. International Journal of Molecular Sciences. 2015,16:24302-24318.SCI
26. Wang P, Zhang N*, Liang J, Li J, Han S, Li J(李俊发)*.Micro-RNA-30a Regulates Ischemia- Induced Cell Death by Targeting Heat Shock Protein HSPA5 in Primary Cultured Cortical Neurons and Mouse Brain After Stroke. Journal of Neuroscience Research. 2015,93:1756-1768.SCI
27. Fu T, Su Q, Xi P, Han S, Li J(李俊发)*.Monocular deprivation delays the dynamic changes of phosphorylated synapsin Ia/b at site-1 in contralateral visual cortex of juvenile mice. Neurochemical Research. 2015, 40:524-530. Neurochemical Research. 2015,40:524-530.SCI
28. Wang P, Liang J, Li Y, Li J, Yang X, Zhang X, Han S, Li S, Li J(李俊发)*.Down-Regulation of miRNA-30a Alleviates Cerebral Ischemic Injury Through Enhancing Beclin 1-Mediated Autophagy. Neurochemical Research. 2014,39:1279–1291.SCI
29. Zhang Z#, Wang X#, Jonas JB, Wang H, Zhang X, Peng X, Ritch R, Tian G, Yang D, Li L, Li J(李俊发)*, Wang N*.Valsalva Manoeuver, Intraocular Pressure, Cerebrospinal Fluid Pressure, Optic Disc Topography: Beijing Intracranial and Intraocular Pressure Study. Acta Ophthalmologica. 2014,92(6):e475-480.SCI
30. Chi W#, Meng F#, Li Y, Li P, Wang G, Cheng H, Han S, Li J(李俊发)*.Impact of microRNA-134 on neural cell survival against ischemic injury in primary neural cell and mouse brain with ischemic stroke by targeting HSPA12B. Brain Research. 2014,1592:22-33.SCI
31. Ren X, Du H, Li Y, Yao X, Huang J, Li Z, Wang W, Li J(李俊发), Han S, Wang C, Huang K.Age-related activation of MKK/p38/NF-κB signaling pathway in lung: From mouse to human. Experimental Gerontology. 2014,57:29-40.SCI
32. Chi W#, Meng F#, Li Y, Li P, Wang Q, Wang G, Han S, Li J(李俊发)*.Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B. Neuroscience. 2014,277:111-122.SCI
33. Peng Z, Li J, Li Y, Yang X, Feng S, Han S, Li J (李俊发)*.Down-regulation of miR-181b in mice brain following ischemic stroke induces neuroprotection against ischemic injury through targeting HSPA5 and UCHL1. Journal of Neuroscience Research. 2013,91:1349-1362.SCI
34. Feng S, Li D, Li Y, Yang X, Han S, Li J (李俊发)*.Insight into hypoxic preconditioning and ischemic injury through determination of nPKCε-interacting proteins in mouse brain. Neurochemistry International. 2013,63(2):69-79.SCI
35. Huang J, Li Z, Yao X, Li Y, Reng X, Li J (李俊发), Wang W, Gao J, Wang C, Tankersley CG, Huang K.Altered Th1/Th2 commitment contributes to lung senescence in CXCR3-deficient mice. Experimental Gerontology. 2013,48(8):717-726.SCI
36. Zhao L, Chu CB, Li J (李俊发), Yang YT, Niu SQ, Qin W, Hao YG, Dong Q, Guan R, Hu WL, Wang Y.Glycogen synthase kinase-3 reduces acetylcholine level in striatum via disturbing cellular distribution of choline acetyltransferase in cholinergic interneurons in rats. Neuroscience. 2013,255:203-211.SCI
37. Wang Q, Zhao Q, Li S, Han S, Peng Z, Li J(李俊发)*.Phosphorylated CaMKII levels increase in rats' central nervous system after large-dose intravenous remifentanil. Medical Science Monitor Basic Research. 2013,19:118-125.SCI
38. Zhao L, Liu X, Liang J, Han S, Wang Y, Yin Y, Luo Y, Li J(李俊发)*.Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in mice. Brain Research. 2013,1503:78-88.SCI
39. Zhang E, Zhu X, Han S, Shan H, Qiu Z, Wang W, Li J(李俊发)*, Yang Y.Increased expressions of TNF ligand related molecule 1A and death receptor 3 in bladder tissues of patients with painful bladder syndrome/interstitial cystitis. Experimental and Therapeutic Medicine. 2013,5:282-286.SCI
40. Yin Y, Wang Y, Chen L, Han S, Zhao L, Luo Y, Li J (李俊发)*.Tat-Collapsin Response Mediator Protein 2 (CRMP2) Increases the Survival of Neurons After NMDA Excitotoxity by Reducing the Cleavage of CRMP2. Neurochemical Research. 2013,38:2095-2104.SCI
41. Zhang N, Li Y, Li J(李俊发)*.Molecular path finding: insight into cerebral ischemic/hypoxic injury and preconditioning by studying PKC-isoform specific signaling pathways. Science Supplemental. 2012,Suppl.:57-58.SCI
42. Shu L, Li T, Han S, Ji F, Pan C, Zhang B, Li J (李俊发)*.Inhibition of neuron-specific CREB dephosphorylation is involved in Propofol and Ketamine-induced neuroprotection against cerebral ischemic injuries of mice. Neurochemical Research. 2012,37:49-58.SCI
43. Shi Y, Wang C, Han S, Pang B, Zhang N, Wang J, Li J (李俊发)*.Determination of PKC isoform-specific protein expression in pulmonary arteries of rats with chronic hypoxia-induced pulmonary hypertension. Medical Science Monitor. 2012,18(2):BR69-75.SCI
44. Liu C, Peng Z, Zhang N, Yu L, Han S, Li D, Li J (李俊发)*.Identification of differentially expressed microRNAs and their PKC-isoform specific gene network prediction during hypoxic preconditioning and focal cerebral ischemia of mice. Journal of Neurochemistry. 2012,120:830-841.SCI
45. Bu X, Zhang N, Yang X, Liu Y, Du J, Liang J, Xu Q, Li J (李俊发)*.Proteomic analysis of cPKCbetaII-interacting proteins involved in HPC-induced neuroprotection against cerebral ischemia of mice. Journal of Neurochemistry. 2011,117(2):346-356.SCI
46. Zhang N, Yin Y, Han S, Jiang J, Yang W, Bu X, Li J (李俊发)*.Hypoxic preconditioning induced neuroprotection against cerebral ischemic injuries and its cPKCgamma-mediated molecular mechanism. Neurochemistry International. 2011,58(6):684-692.SCI
47. Wang Y, Mu X, Wu J, Wu A, Fang L, Li J (李俊发)*, Yue Y.Differential Roles of Phosphorylated AMPA Receptor GluR1 Subunits at Serine-831 and Serine-845 Sites in Spinal Cord Dorsal Horn in a Rat Model of Post-Operative Pain. Neurochemical Research. 2011,36(1):170-176.SCI
48. Li Z, Li J (李俊发), Bu X, Liu X, Tankersley CG, Wang C, Huang K.Age-induced augmentation of p38 MAPK phosphorylation in mouse lung. Experimental Gerontology. 2011,46:694-702.SCI
49. Zhang Y, Su P, Liang P, Liu T, Liu X, Liu XY, Zhang B, Han T, Zhu YB, Yin DM, Li J (李俊发), Zhou Z, Wang KW, Wang Y.The DREAM protein negatively regulates the NMDA receptor through interaction with the NR1 subunit. Journal of Neuroscience. 2010,30(22):7575-7586.SCI
50. Cui W, Li Y, Li S, Wang R, Li J(李俊发)*.Systemic administration of lidocaine reduces morphine requirements and postoperative pain of patients undergoing thoracic surgery after propofol-remifentanil-based anaesthesia. European Journal of Anesthesiology. 2010,27(1):41-46.SCI
51. Qu Y, Shi X, Zhang H, Sun W, Han S, Yu C, Li J(李俊发)*.VCAM-1 siRNA reduces neointimal formation after surgical mechanical injury of the rat carotid artery. Journal of Vascular Surgery. 2009,50(6):1452-1458.SCI
52. Cui X, Li J(李俊发)*, Li T, Ji F, Bu X, Zhang N, Zhang B.Propofol and ketamine induced anesthetic depth-dependent decrease of CaMKII phosphorylation levels in rat hippocampus and cortex. Journal of Neurosurgical Anesthesiology. 2009,21(2):145-154.SCI
53. Cui W, Li Y, Li S, Yang W, Jiang J, Han S, Li J(李俊发)*.Systemic lidocaine inhibits remifentanil-induced hyperalgesia via the inhibition of cPKCgamma membrane translocation in spinal dorsal horn of rats. Journal of Neurosurgical Anesthesiology. 2009,21(4):318-325.SCI
54. Jiang J, Yang W, Huang P, Bu X, Zhang N, Li J(李俊发)*.Increased phosphorylation of Ets-like transcription factor-1 in neurons of hypoxic preconditioned mice. Neurochemical Research. 2009,34:1443-1450.SCI
55. Ding J, Ding N, Wang N, Lu Q, Lu N, Yang D, Bu X, Han S, Li J(李俊发)*.Determination of conventional protein kinase C isoforms involved in high intraocular pressure-induced retinal ischemic preconditioning of rats. Vision Research. 2009,49(3):315-321.SCI
56. Wang Y, Wen Y, Fang Y, Pang H, Guo Z, Shi L, Li J(李俊发).Experimental vasoprotection by a novel erythrocyte-derived depressing factor in rats with arterial calcinosis. Vascul Pharmacol. 2009,50(1-2):65-70.SCI
57. Wu J, Zhang X, Nauta HJ, Lin Q, Li J(李俊发)*, Fang L.JNK1 regulates histone acetylation in trigeminal neurons following chemical stimulation. Biochem. Biophys. Res Commun.. 2008,376:781-786.SCI
58. Liu Y, Li J(李俊发)*, Yang J, Ji F, Bu X, Zhang N, Zhang B.Inhibition of PKCgamma membrane translocation mediated morphine preconditioning-induced neuroprotection against oxygen-glucose deprivationin the hippocampus slices of mice. Neuroscience Letters. 2008,444(1):87-91.SCI
59. Qi X, Lin W, Li J(李俊发), Li H, Wang W, Wang D, Sun M.Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiology of Disease. 2008,31(2):278-285.SCI
60. Qi Z, Bu X, Huang P, Zhang N, Han S, Fang L, Li J(李俊发)*.Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice. Neurochemical Research. 2007,32(9):1450-1459.SCI
61. Bu X, Huang P, Qi Z, Zhang N, Han S, Fang L, Li J(李俊发)*.Cell type-specific activation of p38 mitogen-activated protein kinases in the brain regions of hypoxic preconditioned mice. Neurochemistry International. 2007,51(8):459-466.SCI
62. Wu J, Li J(李俊发), Lin Q, Fang L.Signal transduction in chronic pain. International Anesthesiology Clinics. 2007,45(2):73-81.
63. Jia J, Wang X, Li H, Han S, Zu P, Li J(李俊发)*.Activations of nPKCe and ERK1/2 were involved in oxygen-glucose deprivation induced neuroprotection via NMDA receptors in hippocampal slices of mice. Journal of Neurosurgical Anesthesiology. 2007,19(1):18-24.SCI
64. Kadekaro M, Su G, Chu R, Lei Y, Li J(李俊发)*, Fang L.Effects of nitric oxide on expressions of nitrosocysteine and calcium-activated potassium channels in the supraoptic nuclei and neural lobe of dehydrated rats. Neuroscience Letters. 2007,411(2):117-122.SCI
65. Huang P, Qi Z, Bu X, Zhang N, Han S, Fang L, Li J(李俊发)*.Neuron-specific phosphorylation of mitogen- and stress-activated protein kinase-1 involved in cerebral hypoxic preconditioning of mice. Journal of Neuroscience Research. 2007,85(6):1279-1287.SCI
66. Wu J, Su G, Ma L, Zhang X, Lei Y, Lin Q, Nauta HJ, Li J(李俊发)*, Fang L.The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain. Neurochemistry International. 2007,50(5):710–718.SCI
67. Zhang N, Gao G, Bu X, Han X, Fang L, Li J(李俊发)*.Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2007,423(3):219-224.SCI
68. Wei Y, Wang N*, Lu Q, Zhang N, Zheng D, Li J(李俊发)*.Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia. Neuroscience Letters. 2007,429(2-3):169-174.SCI
69. Guo SW, Liu MG, Long YL, Ren LY, Lu ZM, Yu HY, Hou JF, Li H, Gao CY, Cui XY, An YY, Li JF(李俊发), Zhao LF, Chen J.Region- or state-related differences in expression and activation of extracellular signal-regulated kinases (ERKs) in naive and pain- experiencing rats. BMC Neuroscience. 2007,8(1):53.SCI
70. Kadekaro-M，Su G，Chu R，Lei Y，Li J(李俊发)*，Fang L.Nitirc oxide up-regulates the expression of calcium-dependent potassium channels in thesuproptic nuclei and neueal lobe of rats following dehdration. Neuroscience Letters. 2006,404(1-2):50-55.SCI
71. Li J(李俊发)* , Qu Y, Zu P, Han S, Gao G, Xu Q, Fang L.Increased isoform-specific membrane translocation of conventional and novel protein kinase C in human neuroblastoma SH-SY5Y cells following prolonged hypoxia. Brain Research. 2006,1093(1):25-32.SCI
72. Meng F, Li J(李俊发), Zhang B, Ji F.nPKCe and NMDA receptors participate in neuroprotection induced by morphine pretreatment. Journal of Neurosurgical Anesthesiology. 2006,18(2):119-124.SCI
73. Long C, Gao Y, Gao G, Han S, Zu P, Fang L, Li J(李俊发)*.Decreased phosphorylation and protein expression of ERK1/2 in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2006,397(3):307-312.SCI
74. Gao Y, Gao G, Long C, Han S, Zu P, Fang L, Li J(李俊发)*.Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure. Biochemical and Biophysical Research Communications. 2006,340(2):661-667.SCI
75. Qi X, Lin W, Li J(李俊发), Pan Y, Wang W.The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behavioural Brain Research. 2006,175(2):233-240.SCI
76. Zhao L, Wang N, Jiang L, Long C, Li J(李俊发)*.Unilateral optic nerve transection up-regulate Hsp70 protein expression in lateral geniculate nucleus of rats. Neuroscience Letters. 2006,404(1-2):44-49.SCI
77. Li J(李俊发)*, Yang C, Han S, Zu P, Wu J, Xu Q, Fang L.Increased phosphorylation of neurogranin in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2006,391(3):150-153.SCI
78. Li J(李俊发)*, Niu C, Han S, Zu P, Li H, Xu Q, Fang L.Identification of protein kinase C isoforms involved in cerebral hypoxic preconditioning of mice. Brain Research. 2005,1060(1-2):62-72.SCI
79. Niu C, Li J(李俊发)*, Cui X, Han S, Zu P, Li H, Xu Q.Changes in cPKC isoform-specific membrane translocation and protein expression in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2005,384(1-2):1-6.SCI
80. Wu J, Su G, Ma L, Zhang X, Lei Y, Li J(李俊发), Lin Q, Fang L.Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection. Molecular Pain. 2005,1:26-34.SCI
81. Huang KP, Huang FL, Jager T, Li J(李俊发), Reymann KG, Balschun D.Neurogranin/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling. Journal of Neuroscience. 2004,24(47):10660-10669.SCI
82. Wu J, Li J(李俊发), Huang KP, Huang FL.Attenuation of protein kinase C and camp-dependent protein kinase signal transduction in the neurogranin knockout mouse. Journal of Biological Chemistry. 2002,277(22):19498-19505.SCI
83. Li J(李俊发), Huang FL and Huang KP.Glutathiolation of proteins by glutathione disulfide S-oxide derived from S-nitrosoglutathione. Modifications of rat brain neurogranin/RC3 and neuromodulin/GAP-43. Journal of Biological Chemistry. 2001,276(5):3098-3150.SCI
84. Huang KP, Huang FL, Li J(李俊发), Schuck P, McPhie P.Calcium-sensitive interaction between calmodulin and modified forms of rat brain neurogranin/RC3. Biochemistry. 2000,39(24):7291-7299.SCI
85. Pak JH, Huang FL, Li J(李俊发), Balschun D, Reymann KG, Chiang C, Westphal H, and Huang KP.Involvement of neurogranin in the modulation of calcium/calmodulin- dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knockout mice. Proc Natl Acad Sci U S A (PNAS). 2000,97(21):11232-11237.SCI
86. Liu J, He L, Collins I, Ge H, Libutti D, Li J(李俊发), Egly J, and Levens D.The FBP interacting repressor targets TFIIH to inhibit activated transcription. Molecular Cell. 2000,5:331-341.SCI
87. Li J(李俊发), Pak JH, Huang FL and Huang KP.N-methyl-D-aspartate induces neurogranin/RC3 oxidation in rat brain slices. Journal of Biological Chemistry. 1999,274(3):1294-1300.SCI
主编或副主编的著作/译著
1. 《细胞信号转导研究技术》,主编,中国协和医科大学出版社,200808
重要奖项
1. 上肢远隔缺血适应新技术的建立及其防治缺血性脑卒中的临床应用 教育部科学技术进步奖 一等奖 201812