姓名：尤红 性别：女 职称：研究员、教授 招生院所：附属友谊医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：内科学（消化系病）(博) 内科学（消化系病）(硕) 研究方向名称：肝纤维化/肝硬化的临床诊治和发病机理 电子信箱：youhong30@sina.com


社会任职
1. 中华肝脏病杂志 编委
2. American Journal of Physiology-Gastrointestinal and Liver Physiology 编委
3. Journal of Medical Virology 副主编
4. 国际肝脏病理Laennec组织 中国大陆成员
5. 中华医学会肝病学分会临床流行病学与循证医学协作组 组长
6. 亚太肝病学会（APASL） 执行委员
7. 中华医学会肝病学分会 副主任委员
个人简历
1. 198908-199406:首都医科大学临床医学系 本科
2. 199409-199907:首都医科大学内科(消化） 博士
3. 199907-200011:首都医科大学附属北京友谊医院肝病中心 助理研究员
4. 200011-200311:美国阿肯色州立医科大学基因治疗中心 博士后
5. 200312-201011:首都医科大学附属北京友谊医院肝病中心 副研究员
6. 201011-:首都医科大学附属北京友谊医院肝病中心 研究员
7. 201111-:首都医科大学附属北京友谊医院肝病中心 教授，主任医师
8. 201512-:首都医科大学附属北京友谊医院肝病实验中心 院长助理
9. 201606-:首都医科大学附属北京友谊医院肝病实验中心 科技处处长、实验中心主任
重要学术论文
1. Wei Chen, Aiting Yang, Jidong Jia, Yury V Popov, Detlef Schuppan*, Hong You*.Lysyl oxidase (LOX) family members: rationale and their potential as therapeutic targets for liver fibrosis. Hepatology. 2020,【未填写卷（期）】:【未填写起止页码】.SCI
2. Sun Y, Wu X, Zhou J, Meng T, Wang B, Chen S, Liu H, Wang T, Zhao X, Wu S, Kong Y, Ou X, Wee A, Theise ND, Qiu C, Zhang W, Lu F, Jia J, You H*..Persistent Low Level of Hepatitis B Virus Promotes Fibrosis Progression During Therapy.. Clin Gastroenterol Hepatol. 2020,【未填写卷（期）】:【未填写起止页码】.SCI
3. Wang B, Sun Y, Zhou J, Wu X, Chen S, Shi Y, Wu S, Liu H, Ren Y, Ou X, Jia J, You H*..SHG/TPEF-based image technology improves liver fibrosis assessment of minimally sized needle biopsies. . Hepatol Int. 2019,13(4):501-509.SCI
4. She S#, Wu X#, Zheng D, Pei X, Ma J, Sun Y, Zhou J, Nong L, Guo C, Lv P, Song Q, Zheng C, Liang W, Huang S, Li Q, Liu Z, Song Z, Li Y, Zhang Y, Kong W, You H*, Xi J*, Wang Y*..PSMP/MSMP promotes hepatic fibrosis through CCR2 and represents a novel therapeutic target.. J Hepatol. 2019,72(3):506-518.SCI
5. Liu T, Sun Y, Zhou J, Yang F, Zou X, Wang L, Wu X, Chen Y, Piao H, Lu L, Jiang W, Xu Y, Feng B, Nan Y, Xie W, Chen G, Zheng H, Li H, Ding H, Liu H, Wang T, Ou X, Wu S, Kong Y, Wang P, Cong M, Zhang Y, You H*, Jia J*..On-treatment changes of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein are associated with the regression of liver fibrosis in chronic hepatitis B patients on interferon α add-on therapy. . J Med Virol. 2019,91(8):1499-1509.SCI
6. Kong Y, Sun Y, Zhou J, Wu X, Chen Y, Piao H, Lu L, Ding H, Nan Y, Jiang W, Xu .Early steep decline of liver stiffness predicts histological reversal of fibrosis in chronic hepatitis B patients treated with entecavir. . J Viral Hepat. 2019,26(5):576-585.SCI
7. Sun Y, Zhou J, Wu X, Chen Y, Piao H, Lu L, Ding H, Nan Y, Jiang W, Wang T, Liu H, Ou X, Wee A, Theise ND, Jia J, You H*..Quantitative assessment of liver fibrosis (qFibrosis) reveals precise outcomes in Ishak . Sci Rep. 2018,8(1):2989.SCI
8. Wang B, Sun Y, Zhou J, Wu X, Chen S, Wu S, Liu H, Wang T, Ou X, Jia J, You H*..Advanced septa size quantitation determines the evaluation of histological fibrosis outcome in chronic hepatitis B patients.. Mod Pathol. 2018,31(10):1567-1577.SCI
9. Wu S, Yang Z, Zhou J, Zeng N, He Z, Zhan S, Jia J, You H*..Systematic review: diagnostic accuracy of non-invasive tests for staging liver fibrosis in autoimmune hepatitis.. Hepatol Int. 2018,13(1):91-101.SCI
10. Wu S, Kong Y, Piao H, Jiang W, Xie W, Chen Y, Lu L, Ma A, Xie S, Ding H, Shang J, Zhang X, Feng B, Han T, Xu X, Huo L, Cheng J, Li H, Wu X, Zhou J, Sun Y, Ou X, Zhang H, You H*, Jia J*..On-treatment changes of liver stiffness at week 26 could predict 2-year clinical outcomes in HBV-related compensated cirrhosis.. Liver Int. 2018,38(6):1045-1054.SCI
11. Wu X#, Shi Y#, Zhou J, Sun Y, Piao H, Jiang W, Ma A, Chen Y, Xu M, Xie W, Cheng J, Xie S, Shang J, Cheng J, Xie Q, Ding H, Zhang X, Bai L, Zhang M, Wang B, Chen S, Ma H, Ou X, Jia J*, You H*..Combination of entecavir with thymosin alpha-1 in HBV-related compensated cirrhosis: A prospective multicenter randomized open-label study.. Expert Opinion on Biological Therapy. 2018,18(sup1):61-69.SCI
12. Zhao W, Yang A, Chen W, Wang P, Liu T, Cong M, Xu A, Yan X, Jia J, You H*..Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.. Biochim Biophys Acta.. 2018,1864:1129-1137..SCI
13. Chen W#, Zhao W, Yang A, Xu A, Wang H, Cong M, Liu T, Wang P, You H*..Integrated analysis of microRNA and gene expression profiles reveals a functional regulatory module associated with liver fibrosis.. Gene. 2017,636:87-95.SCI
14. Wang P, Cong M, Liu T, Xu H, Wang L, Sun G, Yang A, Zhang D, Huang J, Sun Y, Zhao W, Ma H, Jia J*, You H*..Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation. Stem Cell Res Ther.. 2017,14;8:183.SCI
15. Sun Y, Zhou J, Wang L, Wu X, Chen Y, Piao H, Lu L, Jiang W, Xu Y, Feng B, Nan Y, Xie W, Chen G, Zheng H, Li H, Ding H, Liu H, Lv F, Shao C, Wang T, Ou X, Wang B, Chen S, Wee A, Theise ND*, You H*, Jia J*..New classification of liver biopsy assessment for fibrosis in chronic hepatitis B patients before and after treatment.. Hepatology.. 2017,65(5):1438-1450.SCI
16. Yang AT, Hu DD, Wang P, Cong M, Liu TH, Zhang D, Sun YM, Zhao WS, Jia JD, You H*..TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis. Stem Cells Int.. 2016,2016:**..SCI
17. You H#, Kong Y#, Hou J, Wei L, Zhang Y, Niu J, Han T, Ou X, Dou X, Shang J, Tang H, Xie Q, Ding H, Ren H, Xu X, Xie W, Liu X, Xu Y, Li Y, Li J, Chow SC, Zhuang H, Jia J*..Female gender lost protective effect against disease progression in elderly patients with chronic hepatitis B.. Sci Rep. . 2016,6:37498. .SCI
18. Wang P*, Yang AT, Cong M, Liu TH, Zhang D, Huang J, Tong XF, Zhu ST, Xu Y, Tang SZ, Wang BE, Ma H, Jia JD, You H*..EGF Suppresses the Initiation and Drives the Reversion of TGF-β1-induced Transition in Hepatic Oval Cells Showing the Plasticity of Progenitor Cells.. J Cell Physiol.. 2015,230(10):2362-70.SCI
19. Wu X, Jia J*, You H*..Thymosin alpha-1 treatment in chronic hepatitis B.. Expert Opin Biol Ther. 2015,2:1-4.SCI
20. You H, Jia J*..Telbivudine treatment in chronic hepatitis B: experience from China.. J Viral Hepat.. 2013,Suppl 1:3-8. .SCI
21. Cong M, Liu T, Wang P, Fan X, Yang A, Bai Y, Peng Z, Wu P, Tong X, Chen J, Li H, Cong R, Tang S, Wang B, Jia J, You H*..Antifibrotic Effects of a Recombinant Adeno-Associated Virus Carrying Small Interfering RNA Targeting TIMP-1 in Rat Liver Fibrosis.. Am J Pathol. . 2013,3:1-8.SCI
22. You H*, Wu X, Ou X, Ma H, Wang Q, Liu T, Cong M, Wang P, Wang B, Jia J..Two patterns of alanine aminotransferase increase to predict long-term viral response in chronic hepatitis B patients: virus- or host-induced? . Antiviral Therapy. 2011,16:299-307.SCI
23. Wang P, Cong M, Liu TH, Yang AT, Cong R, Wu P, Tang SZ, Xu Y, Wang H, Wang BE, Jia JD, You H（责任作者）*..Primary isolated hepatic oval cells maintain progenitor cell phenotypes after two-year prolonged cultivation. J Hepatol. 2010,53(5):863-71.SCI
24. Tianhui Liu, Min Cong, Ping Wang, Jidong Jia, Yong Liu,Paul L. Hermonat,You H（责任作者）*. .Adeno-associated virus Rep78 protein inhibits hepatitis B virus replication through regulation of the HBV core promoter. BBRC. 2009,385:106-111.SCI
25. Wang P, Liu TH, Cong M, Wu XN, Bai YF, Yin CH, An W, Wang BE, Jia JD, You H.(责任作者)*.Expression of Extracellular Matrix Genes in Cultured Hepatic Oval Cells: an origin of hepatic stellate cells through TGF beta. Liver Int.. 2009,29:575-584.SCI
26. You H *, Ma H , Liu T, Cong M, Wang P, Ou XJ, Wang XM, Ren JB, Li HY, Wang BE and Jia JD*.Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles.. J Viral Hepatitis. 2009,16:676-682.SCI
27. Cong M, Liu T, Wang P, Xu Y, Tang S, Wang B, Jia J, Liu Y, Hermonat PL, You H.(责任作者)* .Suppression of tissue inhibitor of metalloproteinase-1 by recombinant adeno-associated viruses carrying siRNAs in hepatic stellate cells.. Int J Mol Med.. 2009,24:685-692.SCI
28. You H, Liu Y, Cong M, Ping W, You C, Zhang D, Mehta JL, Hermonat PL*..HBV genes induce cytotoxic T lymphocyte response upon adeno-associated virus (AAV) vector delivery into dendritic cells.. J Viral Hepatitis. 2006,13:605-612.SCI
主编或副主编的著作/译著
1. 《《自身免疫性肝脏疾病》》,副主编,人民卫生出版社,201808
重要奖项
1. 延边朝鲜族对HCV流行病学及临床转归特点在HCV防控中的应用 吉林省科学技术奖 三等奖 201910
2. 国务院政府特殊津贴 国务院政府特殊津贴 - 2018
3. 乙肝相关性肝病肝移植受者抗乙肝措施应用性研究和临床结局改善 华夏医学科技奖 二等奖 201611
4. 肝纤维化显型表达与非创伤性诊断和临床干预 国家科学技术进步奖 二等奖 201112
5. 肝纤维化防治新靶点与非创伤性诊断及干预措施的应用 中华医学科技奖 三等奖 201112
6. 亚太肝病学会青年研究者奖 亚太肝病学会青年研究者奖 青年研究者奖 2008