姓名：刘文虎 性别：男 职称：主任医师、教授 招生院所：附属友谊医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：内科学（肾病）(博) 内科学（肾病）(硕) 研究方向名称：肾小球疾病，血液净化 电子信箱：wenhuliu@mail.ccmu.edu.cn


社会任职
1. 中华医学会北京分会肾脏病学专业委员会 副主任委员
2. 中华医学会肾脏病分会 常委
3. 首都医科大学肾病学系 主任
4. 中国医师协会肾脏病医师分会 常委
5. 西城区血液净化质量控制与持续改进中心专家委员
6. 北京中西医结合学会第三届肾脏病专业委员会常务委员
7. 临床荟萃杂志第五届编委
8. 中央保健委员会第四届中央保健会诊专家
9. 北京市血液净化质量控制与持续改进中心主任
10. 中国血液净化杂志常务编委
11. 第五届肾脏疾病专业委员会委员
12. 中华医学会肾脏病学分会第十届委员会委员
13. 北京医学会血液净化学分会第一届委员会副主任委员
14. 北京医学会肾脏病学分会第九届委员会副主任委员
15. 中国医药教育协会泌尿与血液净化专业委员会副主任委员兼秘书长
16. 北京血液净化委员会候任主委
个人简历
1. 197909-198407:河北医科大学医学系 学习
2. 198408-198708:河北医科大学 助教
3. 198709-199008:河北医科大学 硕士学习
4. 199008-199708:河北医科大学附属第四医院肾内科 主治医师/副主任医师
5. 199709-200007:军医进修学院 博士学习
6. 200007-200212:首都医科大学附属北京友谊医院肾内科 副主任医师／副教授
7. 200212-200303:首都医科大学附属北京友谊医院肾内科 主任医师／副教授
8. 200303-200512:首都医科大学附属北京友谊医院肾内科 主任医师／副教授/科主任
9. 200512-:首都医科大学附属北京友谊医院肾内科 教授／主任医师/科主任
10. 200804-201804:首都医科大学肾病学系 系主任
11. 201804-:首都医科大学肾病学系 系主任
重要学术论文
1. Zhang AH, Guo WK, Yu L, Liu WH*.Relationship of Serum Soluble Klotho Levels and Echocardiographic Parameters in Patients on Maintenance Hemodialysis. KIDNEY & BLOOD PRESSURE RESEARCH. 2019,44(3):396-404.SCI
2. Chen Xinpan, Wu Yiru, Diao Zongli, Han Xue, Li Dishan, Ruan Xiongzhong,Liu Wenhu*.C1q/tumor necrosis factor‐related protein‐3 improves renal fibrosis via inhibiting notch signaling pathways. JOURNAL OF CELLULAR PHYSIOLOGY. 2019,2019(0):1-13.SCI
3. Liu Y, Wu Y, Diao Z, Guo W, Liu W*.Resveratrol inhibits parathyroid hormone-induced apoptosis in human aortic smooth muscle cells by upregulating sirtuin 1. RENAL FAILURE. 2019,41(1):401-407.SCI
4. Tao Yang, Yanhong Lai, Rui Cui, Yuzhu Wang, Wenhu Liu*.Emergence of Hemodialysis Access-induced Didtal Ischemia in The Maturity Stage of Arteriovenous Fistula. Acta Medica Mediterranea. 2018,34:1085-1090.SCI
5. Yiru Wu, Liyan Wang, Xiaoqi Wang, Yahui Wang, Qidong Zhang, Wenhu Liu*.Renalase contributes to protection against renal fbrosis via inhibiting oxidative stress in rats. INTERNATIONAL UROLOGY AND NEPHROLOGY. 2018,50(7):1347-1354.SCI
6. Xu Z#,Diao Z*,Liu R,Liu W*.The Molecular Mechanism of Smurf2 on Regulating SnoN Expression in Diabetic Nephropathy. . Mol Med Rep. 2017,15(5):2560-2566.SCI
7. Guo W, Diao Z, Liu W*.Asymmetric dimethylarginine downregulates sarco/endoplasmic reticulum calcium‑ATPase 3 and induces endoplasmic reticulum stress in human umbilical vein endothelial cells. Molecular Medicine Reports. 2017,0(0):7541-7547.SCI
8. Wang LY, Diao ZL, Zheng JF, Wu YR, Zhang QD, Liu WH*..Apelin attenuates TGF-β1-induced epithelial to mesenchymal transition via activation of PKC-ε in human renal tubular epithelial cells. PEPTIDES . 2017,96(C):44-52.SCI
9. Yiru Wu, Liyan Wang, Dai Deng, Qidong Zhang and Wenhu Liu *.Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways. Int. J. Mol. Sci.. 2017,18:855.SCI
10. Han X #, Wang LY, Diao ZL , Liu WH*..Apelin: A novel inhibitor of vascular calcification in chronic kidney disease.. Atherosclerosis. 2016,244:1-8.SCI
11. Diao Z#,Liu X,Qian L,Liu J,Liu S,Liu W*. Efficacy and its predictor in microwave ablation for severe secondary hyperparathyroidism in patients undergoing haemodialysis.. Int J Hyperthermia. 2016,32(6):614-622.SCI
12. Li X, Diao Z, Ding J, Liu R, Wang L, Huang W, Liu W*.The downregulation of SnoN expression in human renal proximal tubule epithelial cells under high-glucose conditions is mediated by an increase in Smurf2 expression through TGF-β1 signaling.. Int J Mol Med. 2016,37（2）:415-422.SCI
13. 郭维康, 刁宗礼, 刘文虎*.ADMA 通过引起脐静脉内皮细胞内质网应激而诱导细胞凋亡. 临床和实验医学杂志. 2016,(3):201-203..核心期刊
14. 韩雪, 刘文虎*.Angiotensin Ⅱ/AT1及Apelin/APJ系统与血管钙化关系的研究进展. 北京医学. 2016, 38(1):57-59.核心期刊
15. Liu S, Guo W, Han X, Dai W, Diao Z, Liu W*.Role of UBIAD1 in Intracellular Cholesterol Metabolism and Vascular Cell Calcification.. PLoS One. 2016,11(2):e**.SCI
16. 代文迪, 王丽妍, 刘文虎*. MiR-133和 MiR-294的功能研究进展. 临床和实验医学杂志. 2016,(3):201-203.核心期刊
17. 吴逸如, 刁宗礼, 刘文虎*.硫酸吲哚酚对肾脏和心血管毒性作用的研究新进展.. 临床和实验医学杂志. 2015,（1）:69-72.SCI
18. 刁宗礼, 刘莎, 郭王, 刘旭, 刘文虎*.慢性肾脏病继发性甲状旁腺功能亢进的发病机制研究进展.. 现代生物医学进展. 2015,15（31）:6186-6189.核心期刊
19. 王小琪, 刁宗礼, 郭王, 刘旭, 崔文英, 刘文虎*.维持性血液透析患者原发病变化分析. 北京医学. 2015,37(10):928-931.核心期刊
20. 刁宗礼, 郭维康, 刘莎, 刘文虎*.继发性甲状旁腺功能亢进的药物治疗进展. 中国全科医学. 2015,26:3245-3247,3252.核心期刊
21. 刘旭, 刁宗礼, 刘文虎*. 慢性肾脏疾病肾脏损伤生物标志物的研究进展.. 临床和实验医学杂志. 2015,（20）:1743-1746.核心期刊
22. 丁嘉祥, 郭王, 韩雪, 张金凤, 刘文虎*.不同钙浓度枸橼酸透析液对血钙和甲状旁腺激素水平的影响.. 中华肾脏病杂志. 2015,31（2）:109-114.核心期刊
23. 刘静, 王丽妍, 尹道馨, 冷雪飞, 刘文虎*.血压控制水平对慢性肾脏病患者肾功能的影响研究. 中国全科医学. 2015,(25）:3054-3058.核心期刊
24. Guo W;Ding J;Zhang A;Dai W;Liu S;Diao Z;Wang L;Han X;Liu W.The inhibitory effect of quercetin on asymmetric dimethylarginine-induced apoptosis is mediated by the endoplasmic reticulum stress pathway in glomerular endothelial cells.. Int J Mol Sci. 2014,15（1）:484-503.SCI
25. Liu S,Zhang D,Zhang Q,Liu W*.Interferon-α for IgM nephropathy?. Clinical Nephrology. 2014,82(2):133-137.SCI
26. 郭维康，刘文虎*.司维拉姆与慢性肾脏病高磷血症患者的临床预后. 中国血液净化. 2014,13(6):469-471.核心期刊
27. 韩雪，丁嘉祥，郭王，刘静，刘文虎*.不同缓冲剂碳酸盐透析液对维持性血液透析患者血压及血钙的影响. 中国血液净化. 2014,13（8）:573-576.核心期刊
28. Wang LY,Diao ZL,Zhang DL,Zheng JF,Zhang QD,Ding JX,Liu WH*.The regulatory peptide apelin: a novel inhibitor of renal interstitial fibrosis. Amino Acid. 2014,46(12):2693-2704.SCI
29. Liu S,Diao Z,Zhang D,Ding J,Cui W,Liu W*.Preservation of residual renal function by not removing water in new hemodialysis patients: a randomized, controlled study.. International Urology and Nephrology. 2014,46(1):83-90.SCI
30. Diao Z;Ding J;Yin C;Wang L;Liu W.Purified hepatitis B virus induces human mesangial cell proliferation and extracellular matrix expression in vitro.. Virol J. 2013,10:300.SCI
31. Wang LY;Yin DX;Zhang DL;Xu R;Cui WY;Liu WH.Improvement and influencing factors of blood pressure control by nephrologist referral in chronic kidney disease patients in China: a cohort study.. Int Urol Nephrol. 2013,45（5）:1345-1353.SCI
32. Han X;Zhang DL;Yin DX;Zhang QD;Liu WH.Apelin-13 deteriorates hypertension in rats after damage of the vascular endothelium by ADMA.. Can J Physiol Pharmacol. 2013,91（9）:708-714.SCI
33. Liu S, Zhang DL, Guo W, Cui WY, Liu WH*..LVMI and AoACS are independent mortality predictors of hemodialysis patients: HD compared with HDF. Hemodial Int. . 2012,16(4):504-511.SCI
34. Zhang AH, Wang G, Zhang DL, Zhang QD, Liu S, Liao Y, Yin Y, Liu WH*..Association between VEGF receptors and baseline peritoneal transport status in new peritoneal dialysis patients. Ren Fail. . 2012,34(5):582-589.SCI
35. Dai WD, Liu WH*, Zhang DL..One hemodialysis patient with headache,blurred vision,and hypotension induced by pituitary prolactinoma. Chin Med J (Engl).. 2012,125(15):2787-2789.SCI
36. 张爱华,张东亮,尹道馨,丁嘉祥,刁宗礼,崔文英,赵伟,徐睿,刘文虎*.急性心血管事件是慢性肾脏病相关医疗费用的重要影响因素. 中华肾脏病杂志. 2012,28(8):587-591.核心期刊
37. 代文迪, 张东亮, 刘文虎*.长时程透析对血液透析患者睡眠质量的影响. 中国血液净化. 2012,11(5):249-251.核心期刊
38. Wang L, Zhang D, Zheng J, Feng Y, Zhang Y, Liu W*..Actin cytoskeleton-dependent pathways for ADMA-induced NF-kB activation and TGF-b high expression in human renal glomerular endothelial cells. Acta Biochim Biophys Sin (Shanghai). . 2012,44(11):918-923.SCI
39. Sha Liu,Qi-Dong Zhang,Dong-Liang Zhang,Wen-Hu Liu*.An unusual cause of renomegaly and renal infufficiency: A case report of renal involvement in common variable immunodeficiency disease. Renal Failure. 2011,33(1):92-95.SCI
40. Wei-Kang G, Dong-Liang Z, Xin-Xin W, Wei K, Zhang Y, Qi-Dong Z, Wen-Hu L*. .Actin cytoskeleton modulates ADMA-induced NF-kappaB nuclear translocation and ICAM-1 expression in endothelial cells.. Med Sci Monit. 2011,17(9):242-247.SCI
41. Zhang DL, Liu J, Cui WY, Ji DY, Zhang Y, Liu WH*.. Differences in bio-incompatibility among four biocompatible dialyzer membranes using in maintenance hemodialysis patients.. Ren Fail. 2011,33(7):682-691.SCI
42. Diao Z, Zhang D, Dai W, Ding J, Zhang A, Liu W*..Preservation of residual renal function with limited water removal in hemodialysis patients.. Ren Fail. 2011,33(9) :875-877.SCI
43. Wang LY, Zhang DL, Zheng JF, Zhang Y, Zhang QD, Liu WH*..Apelin-13 passes through the ADMA-damaged endothelial barrier and acts on vascular smooth muscle cells.. Peptides. 2011,32(12):2436-2443.SCI
44. Dong-Liang Zhang,Jing Liu,Sha Liu,Yu Zhang,Wen-Hu Liu*.The differences of asymmetric dimethylarginine removal by different dialysis teatments. Renal Failure. 2010,32(6):935-940.SCI
45. Liu Wen-hu, Tang Ni-na, Zhang Qi-dong.Could mycophenolate mofetil combined with benazapril delay tubulointerstitial fibrosis in 5/6 nephrectomized rats?. Chinese medical journal. 2009,122（2）:199-204.SCI
46. 刘莎，张东亮，代文迪，尹道馨，刘文虎*.糖尿病腹膜透析患者动脉僵硬度及其影响因素. 中国血液净化. 2009,8（4）:192-195.核心期刊
47. 张东亮，廖华，张莉，刘文虎*.非对称性二甲基精氨酸对人阻力血管EDVD的抑制作用. 首都医科大学学报. 2009,30（2）:121-125.核心期刊
48. 于旭芳,周云飞,丰玲,张东亮,刘文虎*.Original article Influence of peritoneal transfer status on fasting blood glucose in non-diabetic nephropathy patients on continuous ambulatory peritoneal dialysis. Chinese Medical Journal. 2009,122(24):2977-2980.SCI
49. 林雅慧，刘静，张东亮，刘文虎*.维持性血液透析患者脆性骨折及骨密度检查情况分析. 中国医药导报. 2008,5（16）:20-22.核心期刊
50. 张东亮，张育，魏媛媛，刘文虎*.血液透析对ADMA的清除作用及与NO生成的相关性研究. 中国血液净化. 2008,7（11）:599-602.核心期刊
51. 权正洪，张东亮，路英华，刘文虎*.220例维持性血液透析患者主动脉弓钙化相关因素分析. 临床荟萃. 2008,23(24):1765.核心期刊
52. 张东亮, 尹道馨，郭王，林雅慧，刘文虎*.鲑鱼降钙素治疗维持性血液透析骨量减少的患者. 中华肾脏病杂志. 2008,24（10）:690-694.核心期刊
主编或副主编的著作/译著
1. 《肾脏病学高级教程》,副主编,人民军医出版社,201409
2. 《实用肾内科查房医嘱手册》,主编,北京大学医学出版社,201201
3. 《临床药物治疗学手册》,副主编,人民卫生出版社,200806
4. 《血液净化通路》,副主编,人民军医出版社,200804
5. 《肾内科患者的治疗与保健》,主编,科学出版社,200606
重要奖项