曾程初博士，北京工业大学教授，博士生导师，全国有机电化学与工业联合会副理事长。目前主要研究方向为功能有机分子的绿色电化学合成方法、技术及工业化应用。已先后主持国家重点研发计划课题、国家自然科学基金(No.**, No. **，**, **)，北京市自然科学基金（No.**，**）以及北京市科技新星计划(No. 2005B10)等研究项目。已在Org. Lett., Angew. Chem., Org. Biomol. Chem., J. Org. Chem.，Eur. J. Org. Chem., Electrochim. Acta, Tetrahedron, Tetrahedron letter，J. Electroanal. Chem. 等国内外有机化学和电化学刊物上共发表SCI论文六十余篇。
一、个人情况简介：
?1995/09-1998/07，华中师范大学有机合成研究所攻读硕士学位（有机合成专业）。
?1998/09-2001/07，中国科学院化学研究所攻读博士学位（有机合成专业），获理学博士学位。
?2001/10-2003/04，以色列Ben-Gurion大学，博士后。
?2003/09—现在，北京工业大学生命学院，教师，副研究员，硕士导师，教授，博士生导师。
?2011/04-2011/08美国加州大学圣塔-芭芭拉分校（UCSB）化学与生物化学系，访问。

二、主要研究方向：
有机电化学合成：将有机化学、电化学和绿色化学的概念、方法和技术引入到化学键的电化学活化及其原位转化中，研究功能有机分子的绿色电化学合成的机理与工业化应用。主要体现在：
1.有机电催化剂的创制及其在合成中的应用
2.电化学原位产生的碱诱导的反应及其在有机合成中的应用
3.基于卤素离子为电催化剂的化学键的电化学形成与断裂的机制及工业化应用
4.高附加值精细化学品的电化学制备：参与开发了某香料中间体的电化学合成新工艺研究，2011年已投产，年产54吨。该工艺经鉴定达到国际领先水平,并获2013年度教育部科技进步二等奖；研发了二酮类系列香料的电化学合成新技术，现正进行工业化开发中。此外还有其他几个产品正在进行中试实验中。
三、主持的研究课题：
1.国家重点研发计划课题：基于卤素离子的间接电催化氧化合成关键技术及其示范（2017YFB**），457万（2017/07-2020/12）
2.国家重点研发计划子课题：食用香料香精和配料绿色制造关键技术研究（2011BAD23B01），113万（2016/7-2020/12）
3.企业委托项目：香料的电化学合成研究，150万（2015/01-2019/12）
4.国家自然科学基金（**）：卤素离子为媒介的电化学氧化偶联形成新的C-C键或C-N键的研究，90万（2015/01-2018/12）
5.国家自然科学基金（**）：新型三芳基咪唑类有机电催化剂的创制及其电氧化活化C-H键和C-C键研究，80万（2013/01-2016/12）
6.国家自然科学基金（**）水相中邻苯醌衍生物的电化学合成与原位转化。 28万（2008/01-2010/12）
7.国家自然科学基金（**）磺酰胺苯乙烯基喹啉: 新型HIV整合酶抑制剂的设计、合成及其构效关系研究。 23万（2005/01-2007/12）
8.北京市科技新星: 以HIV-1整合酶为靶的吡啶（喹喏）酮羧酸衍生物的设计与合成。29万（2005/06-2008/06）
9.北京市自然科学基金：基于“点击化学”的HIV-1整合酶抑制剂的设计与合成 (No. **)，11万（2011/01-2013/12）
10.北京市自然科学基金: HIV整合酶抑制剂：吡啶（喹喏）酮羧酸衍生物的合成 (No. **)， 13万（2006/01-2008/12）

四、参加的研究课题：

1.重大科学研究计划项目：载药纳米颗粒的药效学、生物利用度及其机理研究(No. 2009CB930203）
2.“十二五”科技支撑计划项目：食品香料香精制备关键技术研究及产业化（No: 2011BAD23B01）
3.International associate, the Center for Sustainable Use of Renewable Feedstocks (CenSURF)：http://censurf.chem.ucsb.edu/people/affiliated
4.Participating Chinese member in the PIRE-ECCI program: http://pireecci.ucsb.edu/)

五、学术报告(部分)

1.Invited oral presentation at 68th ISE meeting: Electrochemically oxidative formation of new chemical bonds mediated by halide ions, Providence, Rohde Island, USA, Aug. 27-Sept. 1, 2017
2.Oral presentation at 231 ECS meeting: Electrochemically initiated formation of sulfonyl radicals: synthesis of oxindoles via difunctionalization of acrylamides mediated by bromide ion, New Orleans, Louisiana, USA, may 28-June 1, 2017
3.邀请报告（武汉大学）：Electrocatalytic oxidation in organic synthesis，武汉，2017/05/09
4.邀请报告（北京大学医学部）：Electrocatalytic oxidation in organic synthesis，北京，2017/04/27
5.授课专家（第四届有机化学前沿高级研修班）：Organic electrochemistry (OEC): Fundamentals and applications, 合肥，中国科技大学，2016/12/03
6.邀请报告（江西师范大学）：Organic redox catalysts: synthesis, kinetics and application，江西南昌，2016/10/17
7.邀请报告（井冈山大学）：Organic redox catalysts: synthesis, kinetics and application，江西吉安，2016/10/17
8.Oral presentation at 66th ISE annual meeting: Electrochemically Induced Friedel-Crafts Arylation of Enamides and Chalcone Epoxides by Organic Mediators, Oct. 3-9, 2015, Taipei, Taiwan.
9.Oral presentation at 227 ECS meeting: Electrocatalytic Aziridination of Alkenes in an Undivided Cell Mediated by Iodide，Chicago, Illinois, USA, may 24-28, 2015
10.邀请报告(浙江工业大学寿恒讲坛105讲)：Organic redox catalysts: synthesis, kinetics and application，浙江杭州，Oct. 13, 2015
11.Invited oral presentation at The 12^th international symposium on organic reactions and the 6^th German-Japanese symposium on electrosynthesis: Electrochemical Synthesis of Heterocycles Mediated by Iodide Ion, April 22-24, Kyoto, Japan
12.邀请报告（中国科学院化学研究所）: Organic redox catalysts: synthesis, kinetics and application, 北京, Oct. 30, 2015
13.Keynote Speaker, Electrochemical Conference on Energy & the Environment, Electrochemistry Society (ECS) “Redox catalysts: Metal-free activations of C-H and N-H bonds” Shanghai, China, March 13-16, 2014.
14.Keynote Speaker, PIRE-ECCI annual meeting “Electrochemical synthesis of heterocycles mediated by iodine anion” Shanghai & Hangzhou, China, June 25-29, 2014.
15.大会报告，第十四届全国有机电化学与工业学术会议，“C-H键的间接电化学氧化活化” 海南海口，July 26-29, 2014.
16.Keynote Speaker, PIRE-ECCI annual meeting “Metal-free, electrochemically oxidative functionalization of C-H bonds” Santa Barbara, CA, USA, Dec. 17-20, 2013.

六、研究论文(近五年)

1.Jiang Yang-Ye.; Xu, Kun.; Zeng, Cheng-Chu, * The use of electrochemistry in the synthesis of heterocyclic structures: construction and mechanism, Chem. Rev. (invited and submitted revision)
2.Wang, Qing Qing.; Xu, Kun.; Jiang, Yang-ye; Liu, Yong-Guo.; Sun, Bao-Guo.; and Zeng, ChengChu, * Electrocatalytic Minisci acylation reaction of α-keto acids with N-heteroarenes mediated by NH₄I: Control generation of acyl radical for the selective monoacylation (submitted to Org. Lett.)
3.Yan, Wei-Qing.; Lin, Meng-Ying; R. Daniel Little, Cheng-Chu Zeng* Electrochemical regioselective azidoiodination of alkenes, Tetrahedron 2017, 73, 764-770.
4.Wei-Jing Gao, Chiu Marco Lam, Bao-Guo Sun, R. Daniel Little, Cheng-Chu Zeng* Selective electrochemical C-O bond cleavage of β-O-4 lignin model compounds mediated by iodide ion, Tetrahedron 2017, 73, 2447-2454.
5.Kui-Yong Zhang, Nan-ning Lu, Seung Joon Yoo, Li-Ming Hu, R. Daniel Little, Cheng-Chu Zeng,* Electrochemical analysis of the triarylimidazole-type organic redox catalysts: Chemical stability and homogeneous electron transfer kinetics for the oxidation of 4-methoxybenzyl alcohol Electrochimica Acta 2016, 199, 357-365.
6.Yang-ye Jiang, Qing-Qing Wang, Sen Liang, Li-Ming Hu, R. Daniel Little,* Cheng-Chu Zeng* Electrochemical Oxidative Amination of Sodium Sulfinates: Synthesis of Sulfonamides Mediated by NH4I as a Redox Catalyst J. Org. Chem., 2016, 81, 4713-4719.
7.Sen Liang, Cheng-Chu Zeng,* Hong-Yu Tian, Bao-Guo Sun,* Xu-Gang Luo, Fa-zheng Ren Electrochemically Oxidative α?C?H Functionalization of Ketones: A Cascade Synthesis of α?Amino Ketones Mediated by NH4I J. Org. Chem., 2016, 81, 11565-11573.
8.Sen Liang, Cheng-Chu Zeng,* Xu-Gang Luo, Fa-zheng Ren, Hong-Yu Tian, Bao-Guo Sun* and R. Daniel Little Electrochemically catalyzed amino-oxygenation of styrenes: n-Bu4NI induced C–N followed by a C–O bond formation cascade for the synthesis of indolines Green Chem., 2016, 18, 2222-2230.
9.Yang-Ye Jiang, Sen Liang, Cheng-Chu Zeng,* Li-Ming Hu, Bao-Guo Sun* Electrochemically initiated formation of sulfonyl radicals: synthesis of oxindoles via difunctionalization of acrylamides mediated by bromide ion Green Chem., 2016, 18, 6311-6319.
10.Li-Shuo Kang, Mi-Hai Luo, Chiu Marco Lam, Li-Ming Hu, R. Daniel Little, Cheng-Chu Zeng* Electrochemical C–H functionalization and subsequent C–S and C–N bond formation: paired electrosynthesis of 3-amino-2-thiocyanato-α,β-unsaturated carbonyl derivatives mediated by bromide ions Green Chem., 2016, 18, 3767-3774.
11.Li-Shuo Kang, Huan-lan Xiao, Cheng-Chu Zeng,? Li-Ming Hu, R. Daniel Little, Electrochemical synthesis of benzoxazoles mediated by 2,3-dichloro-5,6-dicyano-p-hydroquinone (DDH) as a redox catalyst, J. Electroanal. Chem., 2016, 767, 13-17.
12.Jie Chen, Wei-Qing Yan, Chiu Marco Lam, Cheng-Chu Zeng,* Li-Ming Hu, and R. Daniel Little*, Electrocatalytic aziridination of alkenes mediated by n-Bu4NI: a radical pathway Org. Lett. 2015, 17, 986-989.
13.Long-Ji Li, Yang-Ye Jiang, Chiu Marco Lam, Cheng-Chu Zeng, * Li-Ming Hu and R. Daniel Little,* Aromatic C-H bond functionalization induced by electrochemically in situ generated tris(p-bromophenyl)aminium (TBPA) radical cation: cationic chain reactions of electron-rich aromatics with enamides J. Org. Chem., 2015, 80, 11021-11030.
14.Jie Chen, Cheng-Fu Liu, Cheng-Wen Yang, Cheng-Chu Zeng*, Wei Liu, Li-Ming Hu, Design and synthesis of 5-chloro-2-hydroxy-3-triazolylbenzoic acids as HIV integrase inhibitors Med. Chem. Res. 2015, 24, 2950-2959.
15.Seung Joon Yoo, Long-Ji Li, Cheng-Chu Zeng, R. Daniel Little* Polymeric Ionic Liquid and Carbon Black Composite as a Reusable Supporting Electrolyte: Modification of the Electrode Surface Angew. Chem. Int. Ed. 2015, 54, 3744-3747.
16.Nan-ning Lu, Ni-tao Zhang, Cheng-Chu Zeng,* Li-Ming Hu, Seung Joon Yoo, R. Daniel Little* Electrochemically induced ring-opening/Friedel-Crafts arylation of chalcone epoxides catalyzed by a triarylimidazole redox mediator J. Org. Chem., 2015, 80, 781-789.
17.Yue-Xia Bai, Long ji Li, Xiao-Li Wang, Cheng-Chu Zeng*, Li-Ming Hu, Design and synthesis of N-hydroxy-triazole-4-carboxamides as HIV integrase inhibitors Med. Chem. Res. 2015, 24, 423-429.
18.Nan-ning Lu, Seung Joon Yoo, Long-Jie Li, Cheng-Chu Zeng, * R. Daniel Little * A comparative study of organic electron transfer redox mediators: electron transfer kinetics for triarylimidazole and triarylamine mediators in the oxidation of 4-methoxybenzyl alcohol Electrochim. Acta, 2014. 142, 254-260.
19.Wei-Jing Gao, Wei-Cui Li, Cheng-Chu Zeng,* Hong-Yu Tian, Li-Ming Hu, R. Daniel Little* Electrochemically initiated oxidative amination of benzoxazoles using tetraalkylammonium halides as redox catalysts J. Org. Chem. 2014, 79，9613-9618.
20.Huan-Lan Xiao, Cheng-Chu Zeng,* Hong-Yu Tian, Li-Ming Hu, R. Daniel Little Electrochemical synthesis of 3,5-disubstituted isoxazoles J. Electroanal. Chem. 2014, 727, 120-124.
21.Yong Dong Liu,* Meric Selbes, Chengchu Zeng, Rugang Zhong, Tanju Karanfil Formation Mechanism of NDMA from Ranitidine, Trimethylamine and Other Tertiary Amines during Chloramination: A Computational Study Environ. Sci. Technol. 2014, 48, 8653?8663.
22.Wei-Cui Li, Zheng-Zheng Zhang, Cheng-Chu Zeng,* Li-Ming Hu, Hong-Yu Tian Electrogenerated Base Induced Dehydrodimerization and Dehydrotrimerization of PyrazolonesCurr. Org. Synth. 2014, 11, 454-460.
23.Xiao-Guang Gao, Ni-Tao Zhang, Cheng-Chu Zeng *, Yong-Dong Liu, Li-Ming Hu, Hong-Yu Tian Electrochemical Synthesis of Polyfunctionalized Indoles in Aqueous Medium from Catechols and Ketene N,S-acetals Curr. Org. Synth. 2014, 11, 141-148.
24.Wei-Cui Li, Cheng-Chu Zeng,* Li-Ming Hu, Hong-Yu Tian, R. Daniel Little Efficient indirect electrochemical synthesis of 2-substituted benzoxazoles using NaI as a mediator Adv. Synth. Cat. 2013, 355, 2884-2890.
25.Chao Li, Cheng-Chu Zeng,* Li-Ming Hu, Feng-Lin Yang, Seung Joon Yoo, R. Daniel Little Electrochemically induced C-H functionalization using bromide ion/TEMPO dual redox catalysts in a two-phase electrolytic system Electrochimica Acta 2013, 114，560-566.
26.Huan-Lan Xiao, Cheng-Wen Yang, Ni-Tao Zhang, Cheng-Chu Zeng*, Li-Ming Hu, Hong-Yu Tian, R. Daniel Little Electrochemical oxidation of aminophenols in the presence of benzenesulfinate Tetrahedron, 2013, 69, 658-663.
27.Ni-tao Zhang, Cheng-chu Zeng,* Chiu Marco Lam, Randi K. Gbur, R. Daniel Little* Triarylimidazole Redox Catalysts: Electrochemical Analysis and Empirical Correlations J. Org. Chem. 2013, 78, 2104-2110.
28.Efrat Korin, Beny Cohen, * Yong-Dong Liu, Cheng-Chu Zeng, * Alexander I. Shames, James Y. Becker* Examining the binding mechanism of 3,4-dihydro-3-(2-oxo-2-phenylethylidene)-quinoxalin-2(1H)-one and its fragments to Cu2+ J. Coord. Chem. 2013, 66, 2351-2366.
29.Zeng, Cheng-Chu*; Zhang Ni-tao; Lam, C. M.; Little, R. D.* Novel triarylimidazole redox catalysts: synthesis, electrochemical properties and applicability to electrooxidative C-H activation Org. Lett. 2012, 14, 1314-1317.
30.Cheng-Wen Yang, Yue-Xia Bai, Ni-Tao Zhang, Cheng-Chu Zeng*, Li-Ming Hu, Hong-Yu Tian One-pot sequential combination of multi-component and multi-catalyst: synthesis of 5-aminobenzofurans from aminophenol and ketene acetals Tetrahedron 2012, 68, 10201-10208.
31.Zhang, Ni-Tao; Gao, Xiao-Guang; Zeng, Cheng-Chu*; Hu, Li-Ming; Tian, Hong-Yu; She, Yuan-Bin Electrochemical oxidation of catechols in the presence of enaminone: exclusive a-arylation RSC Advances, 2012, 2, 298-306.
32.Efrat Korin, Beny Cohen,*, Yue-Xia Bai, Cheng-Chu Zeng,* James Y. Becker,*The effect of substituents on the response of 3,4-dihydro-3-(2-oxo-2-phenylethylidene)-quinoxalin-2(1H)-one derivatives toward binding of Cu2+ Tetrahedron 2012, 68, 7450-7455.
33.Liming Hu,* Song Yan, Zaigang Luo, Xiao Han, Yujie Wang, Zhanyang Wang, Chengchu Zeng Design, Practical Synthesis, and Biological Evaluation of Novel 6-(Pyrazolylmethyl)-4-quinoline-3-carboxylic Acid Derivatives as HIV-1 Integrase Inhibitors Molecules 2012, 17, 10652-10666.

七、授权专利

1.曾程初、李嘉树、田玉福、胡利明邻苯二甲酰肼电化学氧化制备邻苯二甲酸的方法
2.曾程初、张铮铮、钟儒刚、胡利明 5,5’-二羟基- 4,4’-双吡唑类化合物的电化学制备方法中国发明专利，专利号ZL4X.
3.曾程初、张倪涛、白月霞、胡利明三芳基咪唑化合物在电有机合成中作为催化剂的应用，专利号 ZL9.7
4.曾程初、李维翠、高卫静、胡利明2-N-取代苯并噁唑类化合物的电化学催化合成方法，专利号 ZL9.1
5.曾程初、陈杰、陆楠宁、胡利明氮杂环丙烷类化合物的电化学催化合成方法，专利号 ZL7.0
6.胡利明、黄雅理、徐雪梅、曾程初、何红秋、王存新取代苯丙烯基哌嗪基烷基多羟基苯甲酰胺化合物及其制备方法和应用，专利号 ZL 9
7.胡利明、杨磊夫、黄雅理、曾程初1-乙酰基-N-苯基-N-(3-(4-(3-苯基-1-H-吡唑-5-基)哌啶-1-基)丙基)-4-酰胺衍生物及其制备方法，专利号 ZL 2

八、研究生招生方向

博士研究生招生方向：
06药物合成与新技术应用
硕士研究生招生方向：
0710 生物学04 药物化学与化学生物学-05环境生物学与食品安全
085230 生物医学工程（专业学位）04 药物新技术与食品安全

九、联系方式
曾程初博士
北京工业大学生命科学与生物工程学院
北京市朝阳区平乐园100号
Tel.:
E-mail: zengcc@bjut.edu.cn