刘海燕，教授，博士生导师。1990年本科博士毕业于中国科学技术大学生物系。1996年博士毕业于中国科学技术大学，获郭沫若奖。1993-1995年作为联合培养研究生在瑞士苏黎世高等理工学院物理化学实验室学习。1998-2000年在杜克大学和北卡罗来纳大学博士后。现为我校生命科学学院教授、博士生导师。在生物分子计算机模拟与设计方法和酶催化模拟领域发表研究论文六十余篇。2001年获“国家****基金”资助。2004年获安徽省青年科技奖。
实验室主页：http://biocomp.ustc.edu.cn/
主要研究兴趣：
1) 蛋白质空间结构和动力学的计算机模拟方法与应用；
2) 蛋白质设计理论与实验方法及其在合成生物学中的应用。
近期代表性论文:
1. Wei Zhao, Meng Xu, Zhi Liang, Bo Ding, Liwen Niu, Haiyan Liu*, and Maikun Teng*, Structure-based de novo prediction of zinc-binding sites in proteins of unknown function,Bioinformatics2011 27: 1262-1268.
2. Jian Zhan, Bo Ding, Rui Ma, Xiaoyu Ma, Xiaofeng Su, Yun Zhao, Ziqing Liu, Jiarui Wu,Haiyan Liu*, Develop Reusable and Combinable Designs for Transcriptional Logic Gates,Mol Syst Biol2010,6:388.
3. Quan Li, Changhai Zhou, Haiyan Liu*, Fragment-based local statistical potentials derived by combining an alphabet of protein local structures with secondary structures and solvent accessibilities. Proteins. 2009, 74, 820-36.
4. Zanxia Cao, Haiyan Liu*; Using free energy perturbation to predict effects of changing force field parameters on computed conformational equilibriums of peptides;J Chem Phys, 2008, 129, 015101.
5. Cao Xu, Jun Wang,Haiyan Liu*, A Hamiltonian replica exchange approach and its application to the study of side chain type and neighbor effects on peptide backbone conformations, J Chem Theor Comput, 2008,4,1348-1359.
6. Jun Wang, Yan Gu, Haiyan Liu*; Determination of conformational free energies of peptides by multidimensional adaptive umbrella sampling; J Chem Phys2006,125, 094907.
7. Sanmei Cheng, Yuedong Yang, Wenrui Wang, Haiyan Liu*; Transition State Ensemble for the Folding of B Domain of Protein A: A Comparison of Distributed Molecular Dynamics Simulations with Experiments;J Phys Chem B. 2005,109, 23645-23654.
8. Li Xie,Haiyan Liu*, Yang Weitao*; Adapting the nudged elastic band method for determining minimum-energy paths of chemical reactions in enzymes,J Chem Phys, 2004, 120,8039.
9. Jiang Zhu, Qianqian Zhu, Yunyu Shi and Haiyan Liu*; How Good can we predict native contacts in proteins based on decoy structures and their energies? Proteins, 2003,52, 598.
10. Zhiyong Zhang, Yunyu Shi*, andHaiyan Liu*; Molecular dynamics simulations of peptides and proteins with amplified collective motions,Biophys J, 2003, 84, 3583.
联系方式：
Tel: 86-
Fax: 86-
e-mail: hyliu@ustc.edu.cn