王育才博士、教授
中国科学技术大学生命科学学院
中国科学院天然免疫与慢性疾病重点实验
电子邮件：yucaiwang@ustc.edu.cn

王育才，男，教授，博士生导师，2005年于中国科学技术大学获得学士学位；2010年于中国科学技术大学获得博士学位；2011年1月起先后于圣路易斯华盛顿大学生物医学工程系、佐治亚理工学院生物医学工程系及芝加哥大学James Franck研究所从事博士后研究。2015年9月入职中国科学技术大学生命科学学院任教，主持或参与科技部重点研发、基金委重点项目、面上项目等。多年来一直从事纳米材料在癌症治疗及成像领域的研究，在Nat Mater、Nat Commun、PNAS、Nano Letters、ACS Nano国际学术期刊发表研究论文70余篇，引用次数超过5000次，H-index 为39。


工作经历： 2015.9-至今，中国科学技术大学生命科学学院，教授


学习经历： 2001-2005，中国科学技术大学，学士，高分子化学与物理，导师：王均教授
2005-2010，中国科学技术大学，博士，高分子化学与物理，导师：王均教授
2010，美国华盛顿圣路易斯大学生物医学工程系，博士后，导师：夏幼南教授
2011，美国佐治亚理工学院生物医学工程系，博士后，导师：夏幼南教授
2012-2015，美国芝加哥大学James Franck研究所，博士后，导师：田博之教授

所获奖励： 2016年，中-韩生物材料协会青年科学家奖
2018年，全球纳米生物领域45位45岁以下（45 under 45）青年科学家奖

研究方向： 纳米药物，生物材料，生物医用高分子，显微活体成像


获资助国家项目
[1] 聚磷酸酯为亲水壳层的抗肿瘤纳米药物研究，国家自然科学基金面上项目，**，主持，2018.1-2022.12
[2] 基于肿瘤微环境调控的纳米药物研究，“纳米科技”重点专项，2017YFA**，参与
[3] 高分子纳米药物的表面特性控制及其对细胞免疫功能的干预，国家自然科学基金重点项目，**，参与，2017.1-2021.12，
[4] 基于药物分子引发聚合的聚磷酸酯大分子前药的可控合成及其用于癌症治疗，国家自然科学基金面上项目，**，主持，2015.10-2019.10

发表论文(^#为第一作者，^*为通讯作者):
[1]S. Li, Q. Wang, Y. Shen, M. Hassan, J. Shen, W. Jiang, Y. Su, J. Chen, L. Bai, W. C. Zhou,Y. C. Wang.* Pseudoneutrophil Cytokine Sponges Disrupt Myeloid Expansion and Tumor Trafficking to Improve Cancer Immunotherapy.Nano Letters, 2019, in press.
[2]Y.Ma,^#Y. Zhang,^#;X. Li,^#Y. Zhao, M. Li, W. Jiang, X. Tang, J. Dou, L. Lu, F. Wang,*Y. C. Wang.* Near-Infrared II Phototherapy Induces Deep Tissue Immunogenic Cell Death and Potentiates Cancer Immunotherapy.ACS Nano, 2019, 13, 11967-11980.
[3]Y. Ma,^#Y. Zhao,^#N. K. Bejjanki,^#X. Tang, W. Jiang, J. Dou, M. I. Khan, Q. Wang, J. Xia, H. Liu, Y. You, G. Zhang,Y. C. Wang,* J. Wang.Nanoclustered Cascaded Enzymes for Targeted Tumor Starvation and Deoxygenation-Activated Chemotherapy without Systemic Toxicity.ACS Nano, 2019, 13, 8890-8902.
[4]P. Chen,^#Y. Ma,^#Z. Zheng,^#C. Wu,Y. C. Wang,* G. L. Liang,* Facile Syntheses of Conjugated Polymers for Photothermal Tumour Therapy.Nature Communications, 2019, 10:1192.
[5]Y. Zhang,^#Y. Zhao,^#J. Shen,^#X. Sun, Y. Liu, L. Hang, H. Liu,Y. C. Wang,* J. Wang&Nanoenabled Modulation of Acidic Tumor Microenvironment Reverses Anergy of Infiltrating T Cells and Potentiates Anti-PD-1 Therapy.Nano Letters, 2019, 19, 2774-2783.
[6]W.Jiang,^#;Z. Zhang,^#Q. Wang,^# J. Dou, Y. Zhao, Y. Ma, H. Liu, H. X. Xu,*Y. C. Wang.* Tumor Reoxygenation and Blood Perfusion Enhanced Photodynamic Therapy using Ultrathin Graphdiyne Oxide Nanosheets.Nano Letters, 2019, 19, 4060-4067.
[7]Y. Liu,^# N. K. Bejjanki,^#W. Jiang, Y. Zhao, L. Wang, X. Sun, X. Tang, H. Liu,*Y. C. Wang.* Controlled Syntheses of Well-Defined Poly(thionophosphoester)s that Undergo Peroxide-Triggered Degradation.Macromolecules, 2019, 52, 4306-4316.
[8]H. Wang, Y. Hou, Y. Hu, J. Dou, Y. Shen,Y. C. Wang,* H. Lu.* Enzyme-Activatable Interferon-Poly(α-amino acid) Conjugates for Tumor Microenvironment Potentiation.Biomacromolecules,2019, 20, 3000-3008.
[9]L Yang, X Chen, L Wang, Z Hu, N Xin, M Hippler, W Zhu, Y Hu, J Li,Y. C. Wang, L Zhang, D Wu, J Chu. Targeted Single-Cell Therapeutics with Magnetic Tubular Micromotor by One-Step Exposure of Structured Femtosecond Optical Vortices.Advanced Functional Materials, 2019, in press.
[10]W. Huang, X. Zhang, B. Chen, H. Miao, C. O. Trindle,Y. C. Wang, Y. Luo, G. Zhang.* Boosting the Triplet Activity of Heavy-Atom-Free Difluoroboron Dibenzoylmethaneviasp3 Oxygen-Bridged Electron Donors.Chemical Communications, 2019, 55, 67-70
[11]Huang, T. Wu, H. Shi, Y. Wu, H. Yang, K. Zhong,Y. C. Wang, Y. Liu.* Modular Design of Nanobody-Drug Conjugates for Targeted-Delivery of Platinum Anticancer Drug with MRI Contrast Agent.Chemical Communications, 2019, 55, 5175-5178.
[12]B.Chen,X. Zhang,Y. C. Wang, H. Miao, G. Zhang.* Aggregation-Induced Emission with Long-Lived Room-Temperature Phosphorescence from Methylene-Linked Organic Donor-Acceptor Structures,Chemistry-An Asian Journal, 2019, 14, 751-754.
2018
[13]W. Jiang,^#Q. Li,^#L. Xiao,^# J. Dou, Y. Liu, W. Yu, Y. Ma, X. Li, Y. You, Z. Tong, H. Liu, H. Liang, L. Lu, X. Xu, Y. Yao,*G. Zhang,*Y. C. Wang,*J. Wang. Hierarchical Multiplexing Nanodroplets for Imaging-Guided Cancer RadiotherapyviaDNA Damage Enhancement and Concomitant DNA Repair Prevention.ACS Nano, 2018, 12, 5684-5698.
[14]X.Wang,^#Y.Ma,^#X.Sheng,Y.C.Wang,*H.Xu.*Ultrathin Polypyrrole Nanosheets via Space-Confined Synthesis for Efficient Photothermal Therapy in the Second Near-Infrared Window.Nano Letters, 2018, 18, 2217-2225.
[15]W. Jiang,^#Q. Li,^#Z. Zhu,^#Q. Wang, J. Dou, Y. Zhao, W. Lv, F. Zhong, Y. Yao, G. Zhang, H. Liu,*Y. C. Wang,*J. Wang. Cancer Chemoradiotherapy Duo: Nano-Enabled Targeting of DNA Lesion Formation and DNA Damage Response.ACS Applied Materials Interfaces, 2018, 10, 35734-35744.
[16]Z. Ruan,^#Y. Zhao,^#P. Yuan, L. Liu,Y. C. Wang,*L. Yan.*PEG Conjugated BODIPY-Br₂as Macrophotosensitizer for Efficient Imaging-Guided Photodynamic Therapy.Journal of Materials Chemistry B, 2018, 6, 753-762.
[17]L. Huang, B. Chen, X. Zhang, C. Trindle, F. Liao,Y. C. Wang, H. Miao, Y. Luo, G. Zhang.* Proton-Activated Off-On Room-Temperature Phosphorescence from Purely Organic Thioethers.Angewandte Chemie International Edition, 2018, 57, 16046-16050.
[18]X. Du, J.Wang,S Iqbal, H. Li, Z. Cao,Y. C. Wang, J. Du, J Wang.* The Effect of Surface Charge on Oral Absorption of Polymeric Nanoparticles.Biomaterials Science, 2018, 6, 642-650.
[19]Z. Zhao,^#J Long,^#Y. Zhao,J. Yang,W Jiang,Q. Liu,K Yan,L Li,Y. C. Wang.* andZ. X. Lian.* Adaptive Immune Cells are Necessary for the Enhanced Therapeutic Effect of Sorafenib-Loaded Nanoparticles.Biomaterials Science,2018, 6, 893-900.
[20W.Jiang, J. Wang, J. Yang, Z. He, G.Zhang, F. Huang, X. Zhou, L.F. Yan,*X. Z. Yang,*Y. C. Wang,*J. Wang. Acidity-Triggered TAT-Presenting Nanocarriers Augment Tumor Retention and Nuclear Translocation of Drugs.Nano Research,2018, 11, 5716-5734.
2017
[21]J. Yi,^#Y. C. Wang,* Y. Jiang, I. Jung, W. Liu,V. Andrade, R. Xu, R. Parameswaran, I. Peters, R.Divan,X. Xiao, T. Sun, Y. Lee, W. Park,*B. Tian.*3D Calcite Heterostructures for Dynamic and Deformable Mineralized Matrices.Nature Communications, 2017, 8:509.
[22]D.Li,^#G. Zhang,^#W. Xu,^#J. Wang,Y. C. Wang,*L. Qiu, J. Ding,*X. Yang.*Investigating the Effect of Chemical Structure of Semiconducting Polymer Nanoparticle on Photothermal Therapy and Photoacoustic Imaging.Theranostics, 2017, 7, 4029-4040.
[23]J.Chen,^#S. Li,^# Y. Zhang, W. Wang,X. Zhang, Y. Zhao,Y. C. Wang,*H. Bi.*A Reloadable Self-Healing Hydrogel Enabling Diffusive Transport of C-Dots Across Gel-Gel Interface for Scavenging Reactive Oxygen Species.Advanced Healthcare Materials, 2017, 6,**.
[24]Y.Xia,J.Shen,H.Alamri,N.Hadjichristidis,J.P.Zhao,*Y.C.Wang,*and G. Zhang. Revealing the Cytotoxicity of Residues of Phosphazene Catalysts Used for the Synthesis of Poly(ethylene oxide).Biomacromolecules, 2017, 18, 3233-3237.
[25]S. Li,^# F.Wang,^#,*J.Chen, X. Zhang,Y. C. Wang,*;J. Liu.*Dipole Orientation Matters: Longer-circulating Choline Phosphate than Phosphocholine Liposomes for Enhanced Tumor Targeting.ACS Applied Materials Interfaces, 2017,9, 17736-17744.
[26]Y. Zhu, C. Sun, S. Shen, M. I. U. Khan, Y. Zhao, Y. Liu,Y. C. Wang,*J. Wang. A Micellar Cisplatin Prodrug Simultaneously Eliminates both Cancer Cells and Cancer Stem Cells in Lung Cancer.Biomaterials Science, 2017, 5, 1612-1621 (Invited contribution as one of the Emerging Investigators in Biomaterials)
[27]J. Chen, J.Ding,*Y. C. Wang, J. Cheng,*S. Ji, X. Zhuang, X. Chen.*Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors.Advanced Materials, 2017, 29, **.
[28]S. Shen,^#H. Li,^#K. Chen,Y. C. Wang, X Yang,Z Lian, J Du,* J. Wang.* Spatial Targeting of Tumor-Associated Macrophages and Tumor Cells with a pH-Sensitive Cluster Nanocarrier for Cancer Chemoimmunotherapy.Nano Letters, 2017, 17, 3822-3829.
[29]H Huang, H Shi, J Liu, Y Min,Y. C. Wang, A. Z. Wang, J. Wang and Y. Liu*. Co-Delivery of All-Trans-Retinoic Acid Enhances the Anti-Metastasis Effect of Albumin-Bound Paclitaxel Nanoparticles.Chemical Communications,2017, 53, 212-215.
[30]Y. Wang, K. Uetani, S. Liu, X. Zhang,Y. C. Wang, P. Lu, T. Wei, Z Fan, Jing Shen, H. Yu,* S. Li, Q. Zhang, Q. Li, J. Fan, N. Yang, Q. Wang, Y. Liu, J. Cao, J. Li, W. Chen.* Multifunctional Bionanocomposite Foams with a Chitosan Matrix Reinforced by Nanofibrillated Cellulose.ChemNanoMat, 2017, 3, 98-108.
[31]C. Wu,H. Chen,X Wu,X. Cong,L Wang,Y. C. Wang,Y. Yang,W.Li* andT. M. Sun.* The Influence of Tumor-Induced Immune Dysfunction on the Immune Cell Distribution of Gold NanoparticlesIn Vivo.Biomaterials Science,2017, 5, 1531-1536.
2016
[32]M.Zhang*,S.Li,X.Yan,Z.Zhou,M. L. Saha,Y. C. Wang,*P. J. Stang.* Fluorescent Metallacycle-Cored Polymers via Covalent Linkage and Their Use as Contrast Agents for Cell Imaging. Proceedings of the National Academy of Science,2016, 113, 11100-11105.
[33]H. Wang, Z. Zuo, J. Du,Y. C. Wang,* R. Sun, Z. Cao, X. Ye, J. Wang, K. W. Leong,* J. Wang.* Surface Charge Critically Affects Tumor Penetration and Therapeutic Efficacy of Cancer Nanomedicines.Nano Today, 2016, 11, 133-144.
[34]Z. Cao, Z. Chen, C. Sun, H. Li, H. Wang, Q. Cheng, Z. Zuo, J. Wang, Y. Liu,Y. C. Wang,* J. Wang.*Overcoming Tumor Resistance to Cisplatin by Cationic Lipid-Assisted Prodrug Nanoparticles.Biomaterials, 2016,94, 9-19.
[35]Y. Jiang^#, J. C. Souza^#, R. Wong^#, Z. Luo, D. Isheim, X. Zuo, A. Nicholls, I. Jung, J. Yue, D. Liu,Y. C. Wang, V. De Andrade, X. Xiao, L. Navrazhnykh, D. Weiss, X. Wu, D. Seidman, F. Bezanilla,* B. Tian.*Heterogeneous Silicon Mesostructures for Lipid-Supported Bioelectric Interfaces.Nature Materials, 2016,15, 1023-1030.
[36]J.Zimmerman,R. Parameswaran, G.Murray,Y. C. Wang, M. Burke, B. Tian.*Cellular Uptake and Dynamics of Unlabeled Free Standing Silicon Nanowires.Science Advances,2016, 2, e**.
[37]J. Wang, Y. Liu, Y. Ma, C. Sun, W. Tao,Y. C. Wang, X. Yang,*J. Wang. NIR-Activated Super-Sensitive Drug Release Using Nanoparticles with A Flow Core.Advanced Functional Materials, 2016, 26, 7516-7516.
[38]Z. Zuo, K. Chen, X. Yu, G. Zhao, S. Shen, Z. Cao, Y. Luo,Y. C. Wang, J. Wang.*Promoting Tumor Penetration of Nanoparticles for Cancer Stem Cell Therapy by TGF-β Signaling Pathway Inhibition.Biomaterials, 2016, 82, 48-59.
[39]N. Zhou, L. Tian,Y. C. Wang, D. Li, P. Li, X. Zhang, H. Q. Yu.* Extracellular Biosynthesis of Copper SulfideNanoparticles by Shewanella Oneidensis MR-1 as aPhotothermal Agent.Enzyme and Microbial Technology, 2016, 95, 230-235.
2015
[40]Z. Luo,^#Y. Jiang,^#B. Myers, D. Isheim, J. Wu, J. Zimmerman, Z. Wang, Q. Li,Y. C. Wang, X. Chen, V. P. Dravid, D. N. Seidman, B. Tian.*Atomic Gold–Enabled Three-Dimensional Lithography for Silicon Mesostructures.Science, 2015, 348, 1451-1455.
[41]J.Zimmerman, M. Murray,Y. C. Wang, J. Jumper, J. Austin, B. Tian.*Free-Standing Kinked Silicon Nanowires for Probing Inter-and Intracellular Force Dynamics.Nano Letters, 2015, 15, 5492-5498.
2014
[42]Y. C. Wang,^#M. S. Shim,^#N. S. Levinson, H-W. Sung, Y. Xia.*Stimuli-Responsive Materials for Controlled Release of Theranostic Agents.Advanced Functional Materials,2014, 24, 4206-4220.
[43]K. C. L. Black,^#Y. C. Wang,^#H. P. Luehmann, X. Cai, W. X. Xing, B. Pang, Y. F. Zhao, C. S. Cutler, L. V. Wang, Y. Liu,*Y. Xia.*Radioactive¹⁹⁸Au-Doped Nanostructures with Different Shapes forAnalyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution.ACS Nano, 2014, 8, 4385-4394.
[44]. Sun,^#Y. C. Wang,^#F. Wang, J. Du, C. Mao, C. Sun, R. Tang, Y. Liu, J. Zhu, Y.. Zhu, X. Yang, J. Wang.*Cancer Stem Cell Therapy Using Doxorubicin Conjugated to Gold Nanoparticles via Hydrazone Bonds.Biomaterials,2014, 35, 836-845.
[45]T. Sun, Y. Wang,Y. C. Wang, Y. Xia.*Using SV119-Gold Nanocage Conjugates to Eradicate Cancer Stem Cells through a Combination of Photothermal and Chemo Therapies.Advanced Healthcare Materials, 2014, 3, 1283-1291.
2013
[46]Y. C. Wang, Y. Liu,*H. Luehamn, X. Xia, D. Wan, C. Cutler, Y. Xia.*Radioluminescent Gold Nanocages with Controlled Radioactivity for Real-Time in Vivo Imaging.Nano Letters, 2013, 13, 581-585.
[47]Y. C. Wang,^#K. C. L. Black,^# H. Luehmann, W. Li, Y. Zhang, X. Cai, D. Wan, S. Liu, M. Li, P. Kim, Z. Li, L. V. Wang, Y. Liu,*Y. Xia.*Comparison Study of Gold Nanohexapods, Nanorods, and Nanocages for Photothermal Cancer Treatment.ACS Nano, 2013, 7, 2068-2077.
[48]D. Wan, X. Xia,Y. C. Wang,Y. Xia.*Robust Synthesis of Gold Cubic Nanoframes through a Combination of Galvanic Replacement, Gold Deposition, and SilverDealloying.Small, 2013, 9, 3111-7
[49]W. Li, C. Sun, F. Wang,Y. C. Wang, Y. Zhai, M. Liang, W. Liu, Z. Liu, J. Wang,*F. Sun.*Achieving a New Controllable Male Contraception by the Photothermal Effect of Gold Nanorods.Nano Letters,2013, 13, 2477-2484.
[50]K. J. Chen, H. Liang, H. Chen;Y. C. Wang; P. Cheng; Liu, H. L. Liu; Y. Xia,*H. W. Sung.*A Thermoresponsive Bubble-Generating Liposomal System for Triggering Localized Extracellular Drug Delivery.ACS Nano, 2013, 7, 438-446.
[51]Y. Zhang, Y. Wang, L. Wang,Y. C.Wang, X. Cai, C. Zhang, L. V. Wang, Y. Xia.*Labeling Human Mesenchymal Stem Cells with Au Nanocages forin vitroandin Tracking by Two-Photon Microscopy and PhotoacousticMicroscopy. Theranostics, 2013, 3, 532-543.
[52]W. Li, F. Wang, Z. Liu,Y. C. Wang, J. Wang,*F. Sun.*Gold Nanoparticles Elevate Plasma Testosterone Levels in Male Mice without Affecting Fertility.Small,2013, 9, 1708-1714.
[53]H. Wang, M. Xiong,Y. C. Wang,J. Zhu. J. Wang.*N-Acetylgalactosamine Functionalized Mixed Micellar Nanoparticles for Targeted Delivery of siRNA to Liver.Journal of Controlled Release, 2013, 166, 106-114.
[54]J. Wu, T. Sun, X. Yang, J. Zhu, X. Du, Y. Yao, M. Xiong, H. Wang,Y. C. Wang, J. Wang.*Enhanced Drug Delivery to Hepatocellular Carcinoma with a Galactosylated Core–Shell PolyphosphoesterNanogel.Biomaterial Sciences, 2013, 1, 1143-1150.
2012
[55]Y. C. Wang, Y. Liu,*H. Luehmann, X. Xia, P. Brown, C. Jarreau, M. Welch, Y. Xia.*Evaluating the Pharmacokinetics andIn VivoCancer Targeting Capability of Au Nanocages by Positron Emission Tomography Imaging.ACS Nano,2012, 6, 5880-5888.
[56]Y. C. Wang, Y. Wang, F. Zhou, P. Kim, Y. Xia.*Protein-Protected Au Clusters as a New Class of Nanoscale Biosensor for Label-Free Fluorescence Detection of Proteases.Small, 2012, 8, 3769-3773.
[57]S. Xie, M. Jin, J. Tao,Y. C. Wang, Z. Xie, Y. Zhu, Y. Xia.*Synthesis and Characterization of Pd@MxCu1-x (M=Au, Pd, and Pt) Nanocages with Porous Walls and a Yolk-Shell Structure through Galvanic Replacement Reactions.Chemistry of Materials, 2012, 18, 14974-14980.
[58]X. Xia, M. Yang,Y. C. Wang, Y. Zheng, Q. Li, J. Cheng,*Y. Xia.*Quantifying the Coverage Density of Poly(ethylene glycol) Chains on the Surface of Gold Nanostructures.ACS Nano,2012, 6, 512-522.
[59]X. Yang, S. Dou,Y. C. Wang, H. Long, M. Xiong, C. Mao, Y. Yao. J. Wang.*Single-Step Assembly of Cationic Lipid-Polymer Hybrid Nanoparticles for Systemic Delivery of siRNA.ACS Nano,2012, 6, 4955-4965.
[60]M. Xiong, Y. Bao, X. Yang,Y. C. Wang, B. Sun,*J. Wang.*Lipase-Sensitive Polymeric Triple-Layered Nanogel for On-Demand Drug Delivery.Journal of the American Chemical Society, 2012, 134, 4355-4362.
2011
[61]Y. C. Wang, P. Brown, Y. Xia.*;Swarming to the Target.Nature Materials, 2011, 10, 482-483
[62]Y. C. Wang, J. Xu, X. Xia, M. Yang, S. Vangverarong, J. Chen, R. H. Mach, Y. Xia.*SV119-Gold Nanocage Conjugates: a New Platform for Targeting Cancer CellsviaSigma-2 Receptors.Nanoscale, 2011, 4, 421-424.
[63]Y. C. Wang,^#F. Wang,^#T. Sun, J. Wang.*Redox-Responsive Nanoparticles from the Single Disulfide Bond-Bridged Block Copolymer as Drug Carriers for Overcoming Multi-Drug Resistance in Cancer Cells.Bioconjugate Chemistry, 2011, 22, 1939-1945(Most Accessed Articles in Oct.2011)
[64]F.Wang,^#;Y.C.Wang,^#S. Dou, M. Xiong, T. Sun, J. Wang.*Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells.ACS Nano,2011, 5, 3679-3692.
[65]P. Rujitanaroj,Y. C. Wang, J. Wang,and C. S. Yian.*Nanofiber-Mediated Controlled Release of siRNA Complexes for Long Term Gene-Silencing Applications.Biomaterials, 2011, 32, 5915-5923.
;
2010
[66]Y. C. Wang, J. Wu, Y. Li, J. Du, Y. Yuan, J. Wang.*Engineering Nanoscopic Hydrogels via Photo-Crosslinking Salt-Induced Polymer Assembly for Targeted Drug Delivery.Chemical Communications, 2010, 46, 3520-3522.
[67]P.Zhang,L.Hu,Y.C.Wang, J. Wang, L. Feng, Y. P. Li.*Poly(ε-caprolactone)-block-Poly(ethyl Ethylene Phosphate) Micelles for Brain-Targeting Drug Delivery:In Vitro andIn VivoEvaluation.Pharmaceutical Research, 2010, 27, 2657-2669.
[68]Y. C. Wang, Y. Li, T. Sun, M. Xiong, J. Wu, Y. Yang, J. Wang.*Core-Shell-Corona Micelle Stabilized by Reversible Cross-Linkage for Intracellular Drug Delivery.Macromolecular Rapid Communications, 2010, 31, 1201-1206.
[69]Y. C. Wang,Y. Yuan, F. Wang, J. Wang.*Syntheses and Characterization of Block Copolymers of Poly(aliphatic ester) with Clickable Polyphosphoester.Journal of Polymer Science Part A: Polymer Chemistry, 2011, 49, 487-494.
[70]Y. Yuan, Q. Du,Y. C. Wang, J. Wang.*One-Pot Syntheses of Amphiphilic Centipede-Like Brush Copolymers via Combination of Ring-Opening Polymerization and “Click” Chemistry.Macromolecules, 2010, 43, 1739-1746.
2009
[71]L. Tang,Y. C. Wang,*Y. Li, J. Du, J. Wang^*. Shell-Detachable Micelles Based on Disulfide-Linked Block Copolymer as Potential Carrier for Intracellular Drug Delivery.Bioconjugate Chemistry, 2009, 20, 1095-1099.
[72]X.Yang, T. Sun, S. Dou, J. Wu,Y. C. Wang,J. Wang.*Block Copolymer of Polyphosphoester and Poly(L-lactic Acid) Modified Surface for Enhancing Osteoblast Adhesion, Proliferation, and Function.Biomacromolecules, 2009,10, 2213-2220.
[73]Y. C. Wang, Y. Yuan , J. Du, X. Yang, J. Wang.*Recent Progress in Polyphosphoesters: From Controlled Synthesis to Biomedical Applications.Macromolecular Bioscience, 2009, 9, 1154-1164.(Invited Feature Article)
[74]Y. C. Wang, Y. Li, X. Yang, Y. Yuan, L. Yan, J. Wang.*Tunable Thermosensitivity of Biodegradable Polymer Micelles of Poly(ε-caprolactone) and Polyphosphoester Block Copolymers.Macromolecules, 2009, 42, 3026-3032.
[75]Y. C. Wang, L. Tang, J. Wang.*Thermoresponsive Block Copolymers of Poly(ethylene glycol) and Polyphosphoester: Thermo-Induced Self-Assembly, Biocompatibility and Hydrolytic Degradation.Biomacromolecules, 2009, 10, 66-73.
[76]Y. C. Wang, H. Xia, X. Z. Yang, J. Wang.*Synthesis and Thermoresponsive Behaviors of Biodegradable Pluronic Analogs.Journal of Polymer Science Part A: Polymer Chemistry, 2009, 47, 6168-6179.
[77]F. Wang,Y. C. Wang, L. Yan, J. Wang.*Biodegradable Vesicular Nanoparticles Based on Block Copolymer of Poly(e-caprolactone) and Poly(ethyl ethylene phosphate) for Drug Delivery.Polymer, 2009, 50, 5048-5054.
[78]J. Wu, X. Liu,Y. C. Wang, J. Wang.*Template-Free Synthesis of Biodegradable Nanogels with Tunable Sizes as Potential Carriers for Drug Delivery.Journal of Materials Chemistry, 2009, 19, 7856-7863.
[79]Y.Yuan, X. Liu,Y. C. Wang, J. Wang.*Gold Nanoparticles Stabilized by Thermosensitive Diblock Copolymers of Poly(ethylene glycol) and Polyphosphoester.Langmuir, 2009, 25, 10298-10304.
[80]M. Xiong, J. Wu,Y. C. Wang, L. Li, X. Liu, G. Zhang, L. Yan, J. Wang.*Synthesis of PEG-Armed and Polyphosphoester Core-Cross-Linked Nanogel by One-Step Ring-Opening Polymerization.Macromolecules, 2009, 42, 893-896.
2008
[81]J. Cheng, J. Ding,Y. C. Wang, J. Wang.*Synthesis and Characterization of Star-Shaped Block Copolymer of Poly(e-caprolactone) and Poly(ethyl ethylene phosphate) as Drug Carrier.Polymer, 2008, 49, 4784-4790.
[82]Y. C. Wang, L. Tang, T. Sun, C. Li, M. Xiong, J. Wang.*Self-assembled Micelles of Biodegradable Triblock Copolymers Based on Poly(ethyl ethylene phosphate) and Poly(e-caprolactone) as Drug Carriers.Biomacromolecules, 2008, 9, 388-395.
[83]Y. C. Wang, X. Liu, T. Sun, M. Xiong, J. Wang.*Functionalized Micelles from Polyphosphoester and Poly(e-caprolactone) Block Copolymer for Receptor-Mediated Drug Delivery.Journal of Controlled Release, 2008, 128, 32-40.
[84]Y. Yuan, Y. C. Wang, J. Du, J. Wang.*Synthesis of Amphiphilic ABC 3-Miktoarm Star Terpolymer by Combination of Ring Opening Polymerization and “Click” Chemistry.Macromolecules,2008, 41, 8620-8625.
[85]X.Yang,Y.C.Wang, L.Tang, H. Xia, J. Wang.*Synthesis and Characterization of Amphiphilic Block Copolymer of Polyphosphoester and Poly(L-lactic acid).Journal of Polymer Science Part A: Polymer Chemistry, 2008, 46, 6425-6434.
2006
[86]Y. C. Wang, S. Shen, Q. Wu, D. Chen, J. Wang.Gustav Steinhoff, Nan Ma.Block Copolymerization of ε-Caprolactone and 2-Methoxyethyl Ethylene Phosphate Initiated by Aluminum Isopropoxide: Synthesis, Characterization, and Kinetics.Macromolecules,2006, 39, 8992-8998.
[87]C.Xiao,Y.C.Wang,J.Du,X.Chen,J.Wang.*Kineticsand Mechanism of 2-Ethoxy-2-oxo-1,3,2-dioxaphospholane Polymerization Initiated by Stannous Octoate.Macromolecules, 2006, 39, 6825-6831.
[88]J. Du, D. Chen,Y. C. Wang, C. Xiao, Y. Lu, J. Wang,*G. Zhang.Synthesis and Micellization of Amphiphilic Brush-Coil Block Copolymer Based on Poly(ε-caprolactone) and PEGylated Polyphosphoester.Biomacromolecules, 2006, 7, 1898-1963.